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The map label for this gene is dppE [H]

Identifier: 218234625

GI number: 218234625

Start: 1200216

End: 1201871

Strand: Direct

Name: dppE [H]

Synonym: BCB4264_A1234

Alternate gene names: 218234625

Gene position: 1200216-1201871 (Clockwise)

Preceding gene: 218233810

Following gene: 218233900

Centisome position: 22.15

GC content: 33.33

Gene sequence:

>1656_bases
ATGAAGAAAAAGATACCGTTATTACTTGCATCAACTTTAACTGCAAGTATGTTGCTTAGCGCGTGTAGCTACCAAAAAGA
TGACGCAAAAGCAAAAGGGAAAGAGAACGCTACGAGTAGTAGTAACGGAAAACAGATTCTTAATTTAACAGAGTTATCTG
AAATTCCGTCAATGGATGCATCATTGGCATCTGATTCTTCATCTTCTACAGCATTAAATAATACGATGGAAGGTTTATAT
CGTATTGGCAAAGATCAAAAGAGAATGCCTGGAGTTGCAGAAGATGTCGAAAAGCTAGATGATGGGAAGAAATACATATT
TAAATTAAGAAAAGATGCGAAATGGTCGAATGGGGAACCTGTAACAGCTAAAGATTTTGTGTATTCATGGAAAAGAGCAG
TAAATCCAGATACAAAAGCAACGTATTCGTACATTATGTTCGATATTAAAAATGCAGAGAAAATTCATAAAAAAGAATTA
CCTGCTGACCAATTAGGTGTAAAAGCGATTGATGATTATACATTAGAAGTAGAATTAGACAATCCCGTTCCTTACTTTAT
CGATTTAACAGTTTATCCAGTATTTTACCCACTAAATGAAAACTTTGTAAAAGCACAAGGTGATAAATTTGGTTTAGAGG
CAAATACAACATTATATAACGGTCCATTCGTTATGAGTGATTGGAAACATGAACAAAGTTTCCAATTCAAGAAGAATCCT
TCATATTGGGATAATAAAACGGTTAAAATCGAAGAAATCAACTTTAATATTGTAAAAAATACAGCAACTGATGTAAATTT
ATATGAGACAAACGCGATTGACCGAGCGGCTTTAACGTCTGAATTTGTTGATAAGTTTAGAAAAAGTCCAGAGTTCCAAA
CAAGAAAAGAAGCAGGGGTTGCTTACTTAAGATTTAATCAAAGTAATCAGTACTTAAGTAATAAAAACTTAAGAAAAGCA
ATTTCAATGTCCTTTGACCGTGATAACATTGCAAAAGTTATTTTAAATAACGGTGCAATTGGAGCTTACGGATTTGTTGG
AAAAGATTTCGCTGAAGGTCCGAATAAAAAAGATTTCCGAGCTGAAAATGGAAAGCTAGTTGAAACAAATCCAAAAGAAG
CGAAAAAGCTTTGGGAAACAGCGAAGAAAGAGCTTGGAACTGATAAAATCGAACTAGAATTCTTAAACTTTGATAATGAA
GATGCTAAAAAGGTTGGGGAATTCTTAAAAGGTGAGATGGAAAAGAACTTACCAGGTTTATCAATTAAAATTAAACAGCA
ACCATTCGCACAAAAAAATAAATTAGAAGATTCTCAGCAATATGATATTGCGTTTGGTATTTGGGGACCAGATTTCCCAG
ATCCAATCTCATATTTAGATATGTTTGTTACGAATGGTTCTCAAAATAAAACAGGGTATTCTAATCAGAAATATGATGAG
TTAATCCTAAAAGCTAAAACAGATACAAAAGATTTACAAGCTCGCTGGGACAACCTTCTAGAAGTAGAGAAGATGTTAAT
TAAAGAGGATGCAGTTATCACTCCAATCTTCCAAAAAGGTTCAGCGTATGTAGTAAAAGGTGCCGTAAAAGATATTATCC
CAATTAACTATGGTGGTAAATTAACTTACAAATGGGCATCTGTTGAACAAAAATAA

Upstream 100 bases:

>100_bases
TATGTATAATGAAAATTGTAGAAACTTGGAGATTATTCTTTCAATTCTACTTTTTAACAAGTGAGGGTACAGGAAGTGCA
ATTAGGGGAGGCAACACAAC

Downstream 100 bases:

>100_bases
TCTTTTTTTCCATCGTTTACAAGGGTATATGCCTATGATGGGCATATGCTCTTATTTTAAAAAAATAAAAGTAAGAATAT
TTTAAACTATCTTATTGCTT

Product: oligopeptide-binding protein OppA

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 551; Mature: 551

Protein sequence:

>551_residues
MKKKIPLLLASTLTASMLLSACSYQKDDAKAKGKENATSSSNGKQILNLTELSEIPSMDASLASDSSSSTALNNTMEGLY
RIGKDQKRMPGVAEDVEKLDDGKKYIFKLRKDAKWSNGEPVTAKDFVYSWKRAVNPDTKATYSYIMFDIKNAEKIHKKEL
PADQLGVKAIDDYTLEVELDNPVPYFIDLTVYPVFYPLNENFVKAQGDKFGLEANTTLYNGPFVMSDWKHEQSFQFKKNP
SYWDNKTVKIEEINFNIVKNTATDVNLYETNAIDRAALTSEFVDKFRKSPEFQTRKEAGVAYLRFNQSNQYLSNKNLRKA
ISMSFDRDNIAKVILNNGAIGAYGFVGKDFAEGPNKKDFRAENGKLVETNPKEAKKLWETAKKELGTDKIELEFLNFDNE
DAKKVGEFLKGEMEKNLPGLSIKIKQQPFAQKNKLEDSQQYDIAFGIWGPDFPDPISYLDMFVTNGSQNKTGYSNQKYDE
LILKAKTDTKDLQARWDNLLEVEKMLIKEDAVITPIFQKGSAYVVKGAVKDIIPINYGGKLTYKWASVEQK

Sequences:

>Translated_551_residues
MKKKIPLLLASTLTASMLLSACSYQKDDAKAKGKENATSSSNGKQILNLTELSEIPSMDASLASDSSSSTALNNTMEGLY
RIGKDQKRMPGVAEDVEKLDDGKKYIFKLRKDAKWSNGEPVTAKDFVYSWKRAVNPDTKATYSYIMFDIKNAEKIHKKEL
PADQLGVKAIDDYTLEVELDNPVPYFIDLTVYPVFYPLNENFVKAQGDKFGLEANTTLYNGPFVMSDWKHEQSFQFKKNP
SYWDNKTVKIEEINFNIVKNTATDVNLYETNAIDRAALTSEFVDKFRKSPEFQTRKEAGVAYLRFNQSNQYLSNKNLRKA
ISMSFDRDNIAKVILNNGAIGAYGFVGKDFAEGPNKKDFRAENGKLVETNPKEAKKLWETAKKELGTDKIELEFLNFDNE
DAKKVGEFLKGEMEKNLPGLSIKIKQQPFAQKNKLEDSQQYDIAFGIWGPDFPDPISYLDMFVTNGSQNKTGYSNQKYDE
LILKAKTDTKDLQARWDNLLEVEKMLIKEDAVITPIFQKGSAYVVKGAVKDIIPINYGGKLTYKWASVEQK
>Mature_551_residues
MKKKIPLLLASTLTASMLLSACSYQKDDAKAKGKENATSSSNGKQILNLTELSEIPSMDASLASDSSSSTALNNTMEGLY
RIGKDQKRMPGVAEDVEKLDDGKKYIFKLRKDAKWSNGEPVTAKDFVYSWKRAVNPDTKATYSYIMFDIKNAEKIHKKEL
PADQLGVKAIDDYTLEVELDNPVPYFIDLTVYPVFYPLNENFVKAQGDKFGLEANTTLYNGPFVMSDWKHEQSFQFKKNP
SYWDNKTVKIEEINFNIVKNTATDVNLYETNAIDRAALTSEFVDKFRKSPEFQTRKEAGVAYLRFNQSNQYLSNKNLRKA
ISMSFDRDNIAKVILNNGAIGAYGFVGKDFAEGPNKKDFRAENGKLVETNPKEAKKLWETAKKELGTDKIELEFLNFDNE
DAKKVGEFLKGEMEKNLPGLSIKIKQQPFAQKNKLEDSQQYDIAFGIWGPDFPDPISYLDMFVTNGSQNKTGYSNQKYDE
LILKAKTDTKDLQARWDNLLEVEKMLIKEDAVITPIFQKGSAYVVKGAVKDIIPINYGGKLTYKWASVEQK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=494, Percent_Identity=30.5668016194332, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI87081878, Length=489, Percent_Identity=28.2208588957055, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1789397, Length=483, Percent_Identity=25.2587991718427, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1787762, Length=451, Percent_Identity=25.0554323725055, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1789966, Length=488, Percent_Identity=22.5409836065574, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1789887, Length=407, Percent_Identity=22.6044226044226, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1787551, Length=483, Percent_Identity=20.703933747412, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787052, Length=340, Percent_Identity=20.8823529411765, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 62412; Mature: 62412

Theoretical pI: Translated: 8.55; Mature: 8.55

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKIPLLLASTLTASMLLSACSYQKDDAKAKGKENATSSSNGKQILNLTELSEIPSMDA
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCEEEEHHHHHHCCCCCH
SLASDSSSSTALNNTMEGLYRIGKDQKRMPGVAEDVEKLDDGKKYIFKLRKDAKWSNGEP
HHCCCCCCCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
VTAKDFVYSWKRAVNPDTKATYSYIMFDIKNAEKIHKKELPADQLGVKAIDDYTLEVELD
CCHHHHHHHHHHHCCCCCCCEEEEEEEEECCHHHHHHHCCCHHHCCCEEECCEEEEEEEC
NPVPYFIDLTVYPVFYPLNENFVKAQGDKFGLEANTTLYNGPFVMSDWKHEQSFQFKKNP
CCCCEEEEEEEEEEEEECCCCEEEECCCEECCEECCEEECCCEEECCCCCCCCCCCCCCC
SYWDNKTVKIEEINFNIVKNTATDVNLYETNAIDRAALTSEFVDKFRKSPEFQTRKEAGV
CCCCCCEEEEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHCCE
AYLRFNQSNQYLSNKNLRKAISMSFDRDNIAKVILNNGAIGAYGFVGKDFAEGPNKKDFR
EEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCEEECCCCCCHHHCCCCCCCCC
AENGKLVETNPKEAKKLWETAKKELGTDKIELEFLNFDNEDAKKVGEFLKGEMEKNLPGL
CCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCC
SIKIKQQPFAQKNKLEDSQQYDIAFGIWGPDFPDPISYLDMFVTNGSQNKTGYSNQKYDE
EEEECCCCCCHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHH
LILKAKTDTKDLQARWDNLLEVEKMLIKEDAVITPIFQKGSAYVVKGAVKDIIPINYGGK
EEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCHHHEEEECCCCE
LTYKWASVEQK
EEEEECCCCCC
>Mature Secondary Structure
MKKKIPLLLASTLTASMLLSACSYQKDDAKAKGKENATSSSNGKQILNLTELSEIPSMDA
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCEEEEHHHHHHCCCCCH
SLASDSSSSTALNNTMEGLYRIGKDQKRMPGVAEDVEKLDDGKKYIFKLRKDAKWSNGEP
HHCCCCCCCHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCHHHHHHHHHCCCCCCCCC
VTAKDFVYSWKRAVNPDTKATYSYIMFDIKNAEKIHKKELPADQLGVKAIDDYTLEVELD
CCHHHHHHHHHHHCCCCCCCEEEEEEEEECCHHHHHHHCCCHHHCCCEEECCEEEEEEEC
NPVPYFIDLTVYPVFYPLNENFVKAQGDKFGLEANTTLYNGPFVMSDWKHEQSFQFKKNP
CCCCEEEEEEEEEEEEECCCCEEEECCCEECCEECCEEECCCEEECCCCCCCCCCCCCCC
SYWDNKTVKIEEINFNIVKNTATDVNLYETNAIDRAALTSEFVDKFRKSPEFQTRKEAGV
CCCCCCEEEEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHCCE
AYLRFNQSNQYLSNKNLRKAISMSFDRDNIAKVILNNGAIGAYGFVGKDFAEGPNKKDFR
EEEEECCCCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCEEECCCCCCHHHCCCCCCCCC
AENGKLVETNPKEAKKLWETAKKELGTDKIELEFLNFDNEDAKKVGEFLKGEMEKNLPGL
CCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCC
SIKIKQQPFAQKNKLEDSQQYDIAFGIWGPDFPDPISYLDMFVTNGSQNKTGYSNQKYDE
EEEECCCCCCHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHH
LILKAKTDTKDLQARWDNLLEVEKMLIKEDAVITPIFQKGSAYVVKGAVKDIIPINYGGK
EEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCHHHEEEECCCCE
LTYKWASVEQK
EEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]