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The map label for this gene is copA [H]

Identifier: 218234304

GI number: 218234304

Start: 3739165

End: 3741585

Strand: Reverse

Name: copA [H]

Synonym: BCB4264_A3829

Alternate gene names: 218234304

Gene position: 3741585-3739165 (Counterclockwise)

Preceding gene: 218233766

Following gene: 218234499

Centisome position: 69.05

GC content: 36.14

Gene sequence:

>2421_bases
ATGAATGAAAAAAAAGAGGCCAATCTTCAAATATCGGGAATGACATGTGCGGCATGTGCAAATAGAATTGAAAAAGGTCT
AAAAAAAGTAGAAGGTGTTCATGAGGCAAATGTAAATTTTGCACTTGAAAAAACAAAAATAATGTACGATCCAACTAAAA
CAAATCCGCAACAGTTTAAAGAAAAAGTTGAATCGTTAGGATATGGAATTGTAAGTGAAAAAGCTGAATTTACTGTTTCA
GGAATGACATGTGCAGCATGTGCAAATAGAGTTGAAAAGCGTTTAAATAAGTTAGATGGTGTGAACAAAGCGACAGTAAA
TTTTGCTTTAGAATCAGCTACAGTAGACTTTAATCCTGATGAAGTTAATGTAAATGAAATGAAGAGTGCGATTACGAAGC
TAGGATATAAATTAGAAGTCAAACCAGATGATCAAGATGCATCAACTGATCATCGATTACAAGAAATTGAAAGACAAAAG
AAGAAGTTTATTATTTCGTTTATTTTATCTTTCCCATTATTGTGGGCAATGGTTAGTCATTTCTCATTTACGTCGTTTAT
TTATTTACCAGATATGTTAATGAACCCTTGGGTGCAACTAGCACTTGCAACTCCTGTTCAATTTATCATTGGTGGACAGT
TTTATGTTGGAGCTTATAAAGCGTTACGTAATAAAAGTGCGAATATGGATGTTCTCGTGGCGCTTGGAACGTCGGCCGCG
TATTTCTATAGTGTATATTTAAGTATTCAATCTATTGGTTCTTCGAAACATATGACAGATTTATATTTTGAAACGAGTGC
GGTACTTATTACATTAATTATTTTAGGTAAATTATTTGAAGCGAAAGCAAAAGGGCGCTCATCAGAAGCAATTAAAAAAT
TGATGGGTTTACAAGCGAAGACAGCTACAGTTGTGCGAGATGGAACAGAAATAAAAATTTTGATTGAAGAAGTAGTAGCT
GGTGATATCGTCTATGTAAAGCCTGGTGAAAAAATACCAGTAGATGGTGAGATTGTAGAAGGAAAGTCAGCAATTGATGA
ATCGATGTTAACGGGTGAAAGTATTCCTGTTGATAAGTCAATTGGGGATGTAGTAATAGGTTCGACAATAAATAAAAATG
GATTTTTAAAAGTGAAAGCAACTAAGGTAGGAAGAGATACTGCATTAGCTCAAATTATTAAAGTAGTAGAAGAGGCACAA
GGTTCAAAAGCTCCTATTCAAAGGGTAGCAGATCAAATTTCAGGTATTTTCGTACCGGTTGTAGTTGTGATTGCGATTAT
CACATTTGCAGTATGGATGATATTTGTTACACCTGGTGATTTTGGCGGAGCACTTGAGAAAATGATAGCAGTACTTGTTA
TTGCTTGTCCATGTGCATTAGGTCTTGCAACGCCTACATCTATTATGGCAGGATCAGGAAGATCGGCTGAGTATGGTATT
TTATTTAAAGGTGGAGAGCATTTAGAAGCAACGCACCGATTAGATACGGTTATTTTAGATAAAACGGGTACAGTGACAAA
TGGGAAGCCGGTATTAACAGATGTAATTGTAGCAGATGGATTCAATGAAAATGAACTGCTTAGATTAGTAGGGGCAGCAG
AAAGAAATTCTGAACATCCGCTTGCAGAAGCGATTGTAGAAGGAATTAAAGAAAAGAAAATTGATATCCCAAGTTCAGAA
ACGTTTGAAGCGATTCCGGGATTTGGTATCGAATCAGTTGTAGAAGGAAAACACTTATTAATTGGTACACGTCGATTAAT
GAAGAAATTCAATATTGATATTGAAGAAGTTTCTAAATCAATGGAAGCGCTAGAACGAGAAGGAAAAACAGCAATGCTTA
TTGCAATCGATAAAGAATATGCTGGTATAGTTGCCGTTGCAGATACTGTGAAAGATACTTCAAAAGCAGCTATCGCAAGA
CTGAAAAAAATGGGTTTAGACGTTGTGATGATTACAGGAGATAATACACAAACTGCTCAGGCAATTGCAAAGCAAGTTGG
TATTGATCACGTAATTGCAGAAGTATTGCCAGAAGGAAAAGCAGAAGAAGTGAAAAAACTGCAAGCAAATGGTAAGAAAG
TAGCGATGGTTGGAGATGGGATAAATGATGCTCCTGCTCTTGCTACAGCGAACATTGGTATGGCAATTGGAACGGGAACG
GATGTAGCGATGGAAGCAGCGGATATAACGTTAATCCGCGGTGATTTAAATAGTATTGCTGATGCGATCTTTATGAGTAA
AATGACGATAAGAAATATTAAACAAAATTTATTCTGGGCATTAGCTTATAACGCGTTAGGAATTCCAATTGCGGCATTAG
GTTTCTTAGCCCCTTGGGTTGCTGGAGCAGCGATGGCATTTAGTTCTGTATCCGTTGTATTAAATGCATTACGATTACAA
AGAGTTAAATTAAAATCTTAA

Upstream 100 bases:

>100_bases
AATAATTATTTTTAGATATGGAAATAAATCGTACTTTAAATGAAGTACGATTTATTTTGCTAATCATTATACCTCATAAG
GGTATATAGAGGTGAGAGAC

Downstream 100 bases:

>100_bases
AAAGCTACATTAAGTAATTGAATAGAATTAAAAAACAATACTTTGAATAAGTATTGTTTTTTTGTTCGTATAGAAATTAA
AACGATATAATAAAGAAGAA

Product: copper-translocating P-type ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: Protein CopA [H]

Number of amino acids: Translated: 806; Mature: 806

Protein sequence:

>806_residues
MNEKKEANLQISGMTCAACANRIEKGLKKVEGVHEANVNFALEKTKIMYDPTKTNPQQFKEKVESLGYGIVSEKAEFTVS
GMTCAACANRVEKRLNKLDGVNKATVNFALESATVDFNPDEVNVNEMKSAITKLGYKLEVKPDDQDASTDHRLQEIERQK
KKFIISFILSFPLLWAMVSHFSFTSFIYLPDMLMNPWVQLALATPVQFIIGGQFYVGAYKALRNKSANMDVLVALGTSAA
YFYSVYLSIQSIGSSKHMTDLYFETSAVLITLIILGKLFEAKAKGRSSEAIKKLMGLQAKTATVVRDGTEIKILIEEVVA
GDIVYVKPGEKIPVDGEIVEGKSAIDESMLTGESIPVDKSIGDVVIGSTINKNGFLKVKATKVGRDTALAQIIKVVEEAQ
GSKAPIQRVADQISGIFVPVVVVIAIITFAVWMIFVTPGDFGGALEKMIAVLVIACPCALGLATPTSIMAGSGRSAEYGI
LFKGGEHLEATHRLDTVILDKTGTVTNGKPVLTDVIVADGFNENELLRLVGAAERNSEHPLAEAIVEGIKEKKIDIPSSE
TFEAIPGFGIESVVEGKHLLIGTRRLMKKFNIDIEEVSKSMEALEREGKTAMLIAIDKEYAGIVAVADTVKDTSKAAIAR
LKKMGLDVVMITGDNTQTAQAIAKQVGIDHVIAEVLPEGKAEEVKKLQANGKKVAMVGDGINDAPALATANIGMAIGTGT
DVAMEAADITLIRGDLNSIADAIFMSKMTIRNIKQNLFWALAYNALGIPIAALGFLAPWVAGAAMAFSSVSVVLNALRLQ
RVKLKS

Sequences:

>Translated_806_residues
MNEKKEANLQISGMTCAACANRIEKGLKKVEGVHEANVNFALEKTKIMYDPTKTNPQQFKEKVESLGYGIVSEKAEFTVS
GMTCAACANRVEKRLNKLDGVNKATVNFALESATVDFNPDEVNVNEMKSAITKLGYKLEVKPDDQDASTDHRLQEIERQK
KKFIISFILSFPLLWAMVSHFSFTSFIYLPDMLMNPWVQLALATPVQFIIGGQFYVGAYKALRNKSANMDVLVALGTSAA
YFYSVYLSIQSIGSSKHMTDLYFETSAVLITLIILGKLFEAKAKGRSSEAIKKLMGLQAKTATVVRDGTEIKILIEEVVA
GDIVYVKPGEKIPVDGEIVEGKSAIDESMLTGESIPVDKSIGDVVIGSTINKNGFLKVKATKVGRDTALAQIIKVVEEAQ
GSKAPIQRVADQISGIFVPVVVVIAIITFAVWMIFVTPGDFGGALEKMIAVLVIACPCALGLATPTSIMAGSGRSAEYGI
LFKGGEHLEATHRLDTVILDKTGTVTNGKPVLTDVIVADGFNENELLRLVGAAERNSEHPLAEAIVEGIKEKKIDIPSSE
TFEAIPGFGIESVVEGKHLLIGTRRLMKKFNIDIEEVSKSMEALEREGKTAMLIAIDKEYAGIVAVADTVKDTSKAAIAR
LKKMGLDVVMITGDNTQTAQAIAKQVGIDHVIAEVLPEGKAEEVKKLQANGKKVAMVGDGINDAPALATANIGMAIGTGT
DVAMEAADITLIRGDLNSIADAIFMSKMTIRNIKQNLFWALAYNALGIPIAALGFLAPWVAGAAMAFSSVSVVLNALRLQ
RVKLKS
>Mature_806_residues
MNEKKEANLQISGMTCAACANRIEKGLKKVEGVHEANVNFALEKTKIMYDPTKTNPQQFKEKVESLGYGIVSEKAEFTVS
GMTCAACANRVEKRLNKLDGVNKATVNFALESATVDFNPDEVNVNEMKSAITKLGYKLEVKPDDQDASTDHRLQEIERQK
KKFIISFILSFPLLWAMVSHFSFTSFIYLPDMLMNPWVQLALATPVQFIIGGQFYVGAYKALRNKSANMDVLVALGTSAA
YFYSVYLSIQSIGSSKHMTDLYFETSAVLITLIILGKLFEAKAKGRSSEAIKKLMGLQAKTATVVRDGTEIKILIEEVVA
GDIVYVKPGEKIPVDGEIVEGKSAIDESMLTGESIPVDKSIGDVVIGSTINKNGFLKVKATKVGRDTALAQIIKVVEEAQ
GSKAPIQRVADQISGIFVPVVVVIAIITFAVWMIFVTPGDFGGALEKMIAVLVIACPCALGLATPTSIMAGSGRSAEYGI
LFKGGEHLEATHRLDTVILDKTGTVTNGKPVLTDVIVADGFNENELLRLVGAAERNSEHPLAEAIVEGIKEKKIDIPSSE
TFEAIPGFGIESVVEGKHLLIGTRRLMKKFNIDIEEVSKSMEALEREGKTAMLIAIDKEYAGIVAVADTVKDTSKAAIAR
LKKMGLDVVMITGDNTQTAQAIAKQVGIDHVIAEVLPEGKAEEVKKLQANGKKVAMVGDGINDAPALATANIGMAIGTGT
DVAMEAADITLIRGDLNSIADAIFMSKMTIRNIKQNLFWALAYNALGIPIAALGFLAPWVAGAAMAFSSVSVVLNALRLQ
RVKLKS

Specific function: Involved in copper export [H]

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 HMA domains [H]

Homologues:

Organism=Homo sapiens, GI55743071, Length=871, Percent_Identity=41.1021814006889, Blast_Score=599, Evalue=1e-171,
Organism=Homo sapiens, GI115529486, Length=899, Percent_Identity=39.0433815350389, Blast_Score=597, Evalue=1e-170,
Organism=Homo sapiens, GI55743073, Length=841, Percent_Identity=36.6230677764566, Blast_Score=432, Evalue=1e-121,
Organism=Homo sapiens, GI48762689, Length=185, Percent_Identity=35.1351351351351, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI48762685, Length=185, Percent_Identity=35.1351351351351, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI48762691, Length=185, Percent_Identity=35.1351351351351, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI48762687, Length=185, Percent_Identity=35.1351351351351, Blast_Score=91, Evalue=6e-18,
Organism=Homo sapiens, GI28373103, Length=206, Percent_Identity=31.5533980582524, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI28373113, Length=206, Percent_Identity=31.5533980582524, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI28373105, Length=206, Percent_Identity=31.5533980582524, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI28373109, Length=206, Percent_Identity=31.5533980582524, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI28373115, Length=206, Percent_Identity=31.5533980582524, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI28373111, Length=206, Percent_Identity=31.5533980582524, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI28373107, Length=206, Percent_Identity=31.5533980582524, Blast_Score=90, Evalue=9e-18,
Organism=Homo sapiens, GI10835220, Length=206, Percent_Identity=30.5825242718447, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI27886529, Length=206, Percent_Identity=30.5825242718447, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI118498343, Length=171, Percent_Identity=33.9181286549708, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4502285, Length=203, Percent_Identity=29.064039408867, Blast_Score=84, Evalue=5e-16,
Organism=Homo sapiens, GI209413709, Length=203, Percent_Identity=29.064039408867, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI24638454, Length=203, Percent_Identity=29.064039408867, Blast_Score=84, Evalue=6e-16,
Organism=Homo sapiens, GI310128958, Length=195, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=8e-15,
Organism=Homo sapiens, GI297374799, Length=335, Percent_Identity=24.1791044776119, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI83700225, Length=335, Percent_Identity=24.1791044776119, Blast_Score=78, Evalue=4e-14,
Organism=Homo sapiens, GI237681111, Length=274, Percent_Identity=26.2773722627737, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI237681109, Length=274, Percent_Identity=26.2773722627737, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI21361181, Length=274, Percent_Identity=26.2773722627737, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI51944966, Length=267, Percent_Identity=25.0936329588015, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI4502271, Length=261, Percent_Identity=24.904214559387, Blast_Score=71, Evalue=4e-12,
Organism=Homo sapiens, GI22748667, Length=253, Percent_Identity=24.5059288537549, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI153946397, Length=245, Percent_Identity=24.0816326530612, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1786691, Length=841, Percent_Identity=39.5957193816885, Blast_Score=532, Evalue=1e-152,
Organism=Escherichia coli, GI1789879, Length=754, Percent_Identity=33.0238726790451, Blast_Score=350, Evalue=2e-97,
Organism=Escherichia coli, GI1786914, Length=500, Percent_Identity=32.2, Blast_Score=191, Evalue=1e-49,
Organism=Escherichia coli, GI2367363, Length=605, Percent_Identity=23.9669421487603, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17556548, Length=883, Percent_Identity=37.4858437146093, Blast_Score=531, Evalue=1e-151,
Organism=Caenorhabditis elegans, GI17557486, Length=195, Percent_Identity=30.2564102564103, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71988506, Length=206, Percent_Identity=30.0970873786408, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17554158, Length=206, Percent_Identity=30.0970873786408, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI193210130, Length=206, Percent_Identity=30.0970873786408, Blast_Score=90, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71997262, Length=186, Percent_Identity=36.0215053763441, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71997275, Length=186, Percent_Identity=36.0215053763441, Blast_Score=88, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI32566766, Length=193, Percent_Identity=29.5336787564767, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17557770, Length=193, Percent_Identity=29.5336787564767, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71997269, Length=171, Percent_Identity=36.8421052631579, Blast_Score=87, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17541776, Length=215, Percent_Identity=31.6279069767442, Blast_Score=87, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17559224, Length=303, Percent_Identity=26.0726072607261, Blast_Score=77, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17531459, Length=131, Percent_Identity=35.8778625954198, Blast_Score=71, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320475, Length=866, Percent_Identity=34.7575057736721, Blast_Score=444, Evalue=1e-125,
Organism=Saccharomyces cerevisiae, GI6319772, Length=835, Percent_Identity=28.2634730538922, Blast_Score=310, Evalue=5e-85,
Organism=Saccharomyces cerevisiae, GI6321430, Length=546, Percent_Identity=26.7399267399267, Blast_Score=145, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6325221, Length=547, Percent_Identity=26.508226691042, Blast_Score=139, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6321271, Length=188, Percent_Identity=35.1063829787234, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320243, Length=186, Percent_Identity=29.5698924731183, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320244, Length=186, Percent_Identity=29.5698924731183, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321432, Length=216, Percent_Identity=29.6296296296296, Blast_Score=81, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6320245, Length=313, Percent_Identity=25.5591054313099, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221329854, Length=622, Percent_Identity=37.459807073955, Blast_Score=373, Evalue=1e-103,
Organism=Drosophila melanogaster, GI17136664, Length=203, Percent_Identity=29.5566502463054, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24668704, Length=174, Percent_Identity=35.0574712643678, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24762455, Length=207, Percent_Identity=28.9855072463768, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24762453, Length=207, Percent_Identity=28.9855072463768, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24762447, Length=207, Percent_Identity=28.9855072463768, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24762457, Length=207, Percent_Identity=28.9855072463768, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24762449, Length=207, Percent_Identity=28.9855072463768, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24762445, Length=207, Percent_Identity=28.9855072463768, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24762451, Length=207, Percent_Identity=28.9855072463768, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24668708, Length=174, Percent_Identity=35.0574712643678, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24668696, Length=174, Percent_Identity=35.0574712643678, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI161085803, Length=171, Percent_Identity=35.0877192982456, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281366617, Length=174, Percent_Identity=35.0574712643678, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI45553441, Length=302, Percent_Identity=24.8344370860927, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648580, Length=302, Percent_Identity=24.8344370860927, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648578, Length=302, Percent_Identity=24.8344370860927, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45553435, Length=302, Percent_Identity=24.8344370860927, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45553439, Length=302, Percent_Identity=24.8344370860927, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI45553437, Length=302, Percent_Identity=24.8344370860927, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281362164, Length=302, Percent_Identity=24.8344370860927, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648576, Length=277, Percent_Identity=25.6317689530686, Blast_Score=77, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648582, Length=277, Percent_Identity=25.6317689530686, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281366676, Length=254, Percent_Identity=27.5590551181102, Blast_Score=74, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR006122
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 86770; Mature: 86770

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS00154 ATPASE_E1_E2 ; PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKKEANLQISGMTCAACANRIEKGLKKVEGVHEANVNFALEKTKIMYDPTKTNPQQFK
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHCCCEEEEEEEEEEECCCCCCHHHHH
EKVESLGYGIVSEKAEFTVSGMTCAACANRVEKRLNKLDGVNKATVNFALESATVDFNPD
HHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCC
EVNVNEMKSAITKLGYKLEVKPDDQDASTDHRLQEIERQKKKFIISFILSFPLLWAMVSH
CCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSFTSFIYLPDMLMNPWVQLALATPVQFIIGGQFYVGAYKALRNKSANMDVLVALGTSAA
HHHHHHHHHHHHHHCHHHHHHHHCCEEHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCHH
YFYSVYLSIQSIGSSKHMTDLYFETSAVLITLIILGKLFEAKAKGRSSEAIKKLMGLQAK
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCH
TATVVRDGTEIKILIEEVVAGDIVYVKPGEKIPVDGEIVEGKSAIDESMLTGESIPVDKS
HHEEEECCCEEEEEEHHHHCCCEEEECCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCC
IGDVVIGSTINKNGFLKVKATKVGRDTALAQIIKVVEEAQGSKAPIQRVADQISGIFVPV
CCCEEECCEECCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHH
VVVIAIITFAVWMIFVTPGDFGGALEKMIAVLVIACPCALGLATPTSIMAGSGRSAEYGI
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCEEE
LFKGGEHLEATHRLDTVILDKTGTVTNGKPVLTDVIVADGFNENELLRLVGAAERNSEHP
EEECCCCCHHHHHHCEEEEECCCCCCCCCCHHEEEEEECCCCHHHHHHHHHHHCCCCCCC
LAEAIVEGIKEKKIDIPSSETFEAIPGFGIESVVEGKHLLIGTRRLMKKFNIDIEEVSKS
HHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHH
MEALEREGKTAMLIAIDKEYAGIVAVADTVKDTSKAAIARLKKMGLDVVMITGDNTQTAQ
HHHHHHCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
AIAKQVGIDHVIAEVLPEGKAEEVKKLQANGKKVAMVGDGINDAPALATANIGMAIGTGT
HHHHHHCHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEECCCCEEECCCC
DVAMEAADITLIRGDLNSIADAIFMSKMTIRNIKQNLFWALAYNALGIPIAALGFLAPWV
CCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AGAAMAFSSVSVVLNALRLQRVKLKS
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNEKKEANLQISGMTCAACANRIEKGLKKVEGVHEANVNFALEKTKIMYDPTKTNPQQFK
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHCCCHHCCCEEEEEEEEEEECCCCCCHHHHH
EKVESLGYGIVSEKAEFTVSGMTCAACANRVEKRLNKLDGVNKATVNFALESATVDFNPD
HHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCC
EVNVNEMKSAITKLGYKLEVKPDDQDASTDHRLQEIERQKKKFIISFILSFPLLWAMVSH
CCCHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSFTSFIYLPDMLMNPWVQLALATPVQFIIGGQFYVGAYKALRNKSANMDVLVALGTSAA
HHHHHHHHHHHHHHCHHHHHHHHCCEEHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCHH
YFYSVYLSIQSIGSSKHMTDLYFETSAVLITLIILGKLFEAKAKGRSSEAIKKLMGLQAK
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCH
TATVVRDGTEIKILIEEVVAGDIVYVKPGEKIPVDGEIVEGKSAIDESMLTGESIPVDKS
HHEEEECCCEEEEEEHHHHCCCEEEECCCCCCCCCCEEECCHHHHHHHHHCCCCCCCCCC
IGDVVIGSTINKNGFLKVKATKVGRDTALAQIIKVVEEAQGSKAPIQRVADQISGIFVPV
CCCEEECCEECCCCEEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHH
VVVIAIITFAVWMIFVTPGDFGGALEKMIAVLVIACPCALGLATPTSIMAGSGRSAEYGI
HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCEEE
LFKGGEHLEATHRLDTVILDKTGTVTNGKPVLTDVIVADGFNENELLRLVGAAERNSEHP
EEECCCCCHHHHHHCEEEEECCCCCCCCCCHHEEEEEECCCCHHHHHHHHHHHCCCCCCC
LAEAIVEGIKEKKIDIPSSETFEAIPGFGIESVVEGKHLLIGTRRLMKKFNIDIEEVSKS
HHHHHHHHHHHCCCCCCCCCCHHHCCCCCHHHHHCCCCEEEHHHHHHHHHCCCHHHHHHH
MEALEREGKTAMLIAIDKEYAGIVAVADTVKDTSKAAIARLKKMGLDVVMITGDNTQTAQ
HHHHHHCCCEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHH
AIAKQVGIDHVIAEVLPEGKAEEVKKLQANGKKVAMVGDGINDAPALATANIGMAIGTGT
HHHHHHCHHHHHHHHCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCEEECCCCEEECCCC
DVAMEAADITLIRGDLNSIADAIFMSKMTIRNIKQNLFWALAYNALGIPIAALGFLAPWV
CCEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AGAAMAFSSVSVVLNALRLQRVKLKS
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 12644235; 11922674; 12590580 [H]