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The map label for this gene is copZ [H]

Identifier: 218233766

GI number: 218233766

Start: 3741681

End: 3741887

Strand: Reverse

Name: copZ [H]

Synonym: BCB4264_A3830

Alternate gene names: 218233766

Gene position: 3741887-3741681 (Counterclockwise)

Preceding gene: 218232830

Following gene: 218234304

Centisome position: 69.05

GC content: 38.65

Gene sequence:

>207_bases
ATGGAACAGTTAACATTACAGGTTGAAGGTATGTCTTGTGGACATTGTGTAAATGCTATCGAAAGCAGTGTGAAAGAGCT
AAACGGTGTTGAACAAGTGAAGGTTCAATTAGCAGAAGGAACTGTTGAAGTTACTATCGACTCGTCTGCCGTAACATTAA
AAGATATCGTTGCTGTAATCGAAGACCAAGGATACGATGTTCAATAA

Upstream 100 bases:

>100_bases
ATTGAAAAATCATGATATAAAACCATTGATTACCTTAGGGGGGTATGGTAAGATGTAATTGTGATTAACAAACAATGAAT
AAACAAGAGGAGGATTTTAA

Downstream 100 bases:

>100_bases
TTATTTTTAGATATGGAAATAAATCGTACTTTAAATGAAGTACGATTTATTTTGCTAATCATTATACCTCATAAGGGTAT
ATAGAGGTGAGAGACATGAA

Product: copper-ion-binding protein

Products: ADP; Orthophosphate. [C]

Alternate protein names: Copper-ion-binding protein [H]

Number of amino acids: Translated: 68; Mature: 68

Protein sequence:

>68_residues
MEQLTLQVEGMSCGHCVNAIESSVKELNGVEQVKVQLAEGTVEVTIDSSAVTLKDIVAVIEDQGYDVQ

Sequences:

>Translated_68_residues
MEQLTLQVEGMSCGHCVNAIESSVKELNGVEQVKVQLAEGTVEVTIDSSAVTLKDIVAVIEDQGYDVQ
>Mature_68_residues
MEQLTLQVEGMSCGHCVNAIESSVKELNGVEQVKVQLAEGTVEVTIDSSAVTLKDIVAVIEDQGYDVQ

Specific function: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-transporting ATPase CopA [H]

COG id: COG2608

COG function: function code P; Copper chaperone

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HMA domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001757
- InterPro:   IPR000428
- InterPro:   IPR006122
- InterPro:   IPR017969
- InterPro:   IPR006121 [H]

Pfam domain/function: PF00403 HMA [H]

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 7279; Mature: 7279

Theoretical pI: Translated: 3.79; Mature: 3.79

Prosite motif: PS01047 HMA_1 ; PS50846 HMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLTLQVEGMSCGHCVNAIESSVKELNGVEQVKVQLAEGTVEVTIDSSAVTLKDIVAVI
CCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHEEEECCCEEEEEECCCCHHHHHHHHHH
EDQGYDVQ
HCCCCCCC
>Mature Secondary Structure
MEQLTLQVEGMSCGHCVNAIESSVKELNGVEQVKVQLAEGTVEVTIDSSAVTLKDIVAVI
CCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHEEEECCCEEEEEECCCCHHHHHHHHHH
EDQGYDVQ
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12644235; 12600214; 14621987 [H]