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The map label for this gene is tkt1 [H]

Identifier: 218234257

GI number: 218234257

Start: 3264191

End: 3266185

Strand: Reverse

Name: tkt1 [H]

Synonym: BCB4264_A3388

Alternate gene names: 218234257

Gene position: 3266185-3264191 (Counterclockwise)

Preceding gene: 218233527

Following gene: 218232908

Centisome position: 60.27

GC content: 40.0

Gene sequence:

>1995_bases
ATGACACAAAACATAAATCAATTAGCAGTGAATACAATTCGTACGTTATCAATTGATGCTATTAATGCGGCAAATTCAGG
TCATCCAGGTCTTCCGATGGGAGCAGCACCGATGGCTTATGCATTATGGGCGAATCATTTAAATCACAATCCTAATCATC
CGAAATGGTTTAACCGTGATCGATTCGTTCTATCAGCGGGACACGGATCGAGCCTACTGTATAGCTTACTTCATTTAGCT
GGATATGACGTTTCAATTGATGACTTGAAAAACTTCAGAAAGTTAAATAGTAAAACACCAGGACATCCTGAGTTTGGTCA
TACTCCTGGAGTTGAAGCGACGACAGGCCCGTTAGGACAAGGGATTGCTAATGCTGTCGGAATGGCAATGGCAGAAGCTC
ATTTAGCAGCGAAGTTCAATAAGGATGGTCACTCTATTATAGATCACAATACGTACGCATTAGTCGGAGATGGTGACTTA
ATGGAGGGTGTCGCTTATGAAGCGATGTCAATGGCAGGACATATGAAACTTGGCAAGTTAATTGTACTGTACGATTCAAA
TGAAATTTCACTTGATGGTGAATTAGGCATTGCTTTCTCTGAAGATATTGAGAAAAGGGCAGAATCTGTACATTGGCAAT
ATGTAAGAGTTGAAGATGGAAACGATGTCGATGCTATTACAAAAGCCATTACATTAGCGAAAGAAAATACGGATCAACCT
ACTCTTATAGAAATTAGAACCATTATAGGTTATGGAAGTCCAAAAGTTGCTGGAACGAACAAAGCACATGGTAATCCGCT
TGGAGTAGAAGAGGCAACAGCGACAAAACAAGTGTATGGTTGGGATTATGAGGAAGACTTCTTTGTGCCTGAAGAAGTAA
CAGCTCATTTTAATGAACTGAAACAAAAAGGTATTGAAAAAGAGAATGAATGGAATGAGCAGTTCAACGTATACAGAGAG
TCAAACCCTGCACTAGCAGATGAATTAGAAAAAGCGATTACAGGTGAGGTTTTAATCGAAGCGAAAGACATTCTATCCTT
TGATACTGAAAAAACGATTTCTACTCGTGTTGCAAGTGGGGAAGCTATTAATCATTATGTGAAAACGATTCCTTCTATTT
TCGGTGGAAGTGCAGATCTTTCTCATTCTACGATGACAGATATAAAAGGTGAAGCAGTATATGCAGTAGAATCGTATGCT
GGCCGCAATATATACTTCGGTGTACGTGAACATGCAATGGGCGCGGCAGCGAATGGACTGGCTCTTCATGGAGGGGTAAA
ACCATTCGTAAGTACATTCTTTGTATTTAATGACTATCTTCGTCCATCGATTCGACTTGCTGCACTGCAAAAGTTACCTG
TTACTTACGTATTTACACATGATTCGATCGCTGTAGGAGAAGATGGTCCAACGCATGAACCTATTGAACATTTAGCAGCT
CTTCGTGCAATTCCTGGTTTAACAGTTATCCGCCCGTCAGATGCAAATGAAACAGCAAGTGCGTGGGCGTATGCATTACA
GCAAACGGATGGTCCAGTCGTTTTAGTACTGAGTCGTCAAAATTTACCGGTGTTTAATGAAACGAAAGCGAACATAGAGA
ATCTCTCTAAAGGAGCTTACGTATTAACGGAAACAAATGAAAATCCGGATGTAATTTTAATTGCGACAGGTTCTGAAGTA
TCTTTAGCTGCTAGTGCAAAAGCAAAACTAGAAGAAGACAATGTCTCTGTTCGCATCGTTGCAATGCCGAGCTGGGAGTT
ATTTGATCGCCAATCGAACGAATATAAAGAATCCGTTCTTCCGTCTTCTATAACGAAACGAGTATCTCTTGAGATGGGTG
TATCTCTCGGTTGGGAACGTTATGTAGGGCAAGAAGGAAAAGTACTATCAATTGAAACATTTGGAGCTTCAGGTACTGGA
GCTGAAGTCATGAATCTATTTGGATTTACGATAGAAAATGTTGTTCAAATTACAAAAAATGTGTTGAATTCTTAA

Upstream 100 bases:

>100_bases
GAATGAATTATTGCAAGAAAGTGGATTTAAATGGTGGTTAGATCAAGAAACGGAAAAATAAGTACTTTCTTTCATGAAAG
CATGTAGGGGGACGATTACT

Downstream 100 bases:

>100_bases
GCTATGACTGTGAATACCTTTCTAGATTTATCAATACTGAATGGTATTCAAAATCGTAGTGATATGAATTTTTAATAAAA
GATAATCTGAGGAGGAATTA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSSLLYSLLHLA
GYDVSIDDLKNFRKLNSKTPGHPEFGHTPGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDL
MEGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELGIAFSEDIEKRAESVHWQYVRVEDGNDVDAITKAITLAKENTDQP
TLIEIRTIIGYGSPKVAGTNKAHGNPLGVEEATATKQVYGWDYEEDFFVPEEVTAHFNELKQKGIEKENEWNEQFNVYRE
SNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGEAINHYVKTIPSIFGGSADLSHSTMTDIKGEAVYAVESYA
GRNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
LRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFNETKANIENLSKGAYVLTETNENPDVILIATGSEV
SLAASAKAKLEEDNVSVRIVAMPSWELFDRQSNEYKESVLPSSITKRVSLEMGVSLGWERYVGQEGKVLSIETFGASGTG
AEVMNLFGFTIENVVQITKNVLNS

Sequences:

>Translated_664_residues
MTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSSLLYSLLHLA
GYDVSIDDLKNFRKLNSKTPGHPEFGHTPGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDL
MEGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELGIAFSEDIEKRAESVHWQYVRVEDGNDVDAITKAITLAKENTDQP
TLIEIRTIIGYGSPKVAGTNKAHGNPLGVEEATATKQVYGWDYEEDFFVPEEVTAHFNELKQKGIEKENEWNEQFNVYRE
SNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGEAINHYVKTIPSIFGGSADLSHSTMTDIKGEAVYAVESYA
GRNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
LRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFNETKANIENLSKGAYVLTETNENPDVILIATGSEV
SLAASAKAKLEEDNVSVRIVAMPSWELFDRQSNEYKESVLPSSITKRVSLEMGVSLGWERYVGQEGKVLSIETFGASGTG
AEVMNLFGFTIENVVQITKNVLNS
>Mature_663_residues
TQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRDRFVLSAGHGSSLLYSLLHLAG
YDVSIDDLKNFRKLNSKTPGHPEFGHTPGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDLM
EGVAYEAMSMAGHMKLGKLIVLYDSNEISLDGELGIAFSEDIEKRAESVHWQYVRVEDGNDVDAITKAITLAKENTDQPT
LIEIRTIIGYGSPKVAGTNKAHGNPLGVEEATATKQVYGWDYEEDFFVPEEVTAHFNELKQKGIEKENEWNEQFNVYRES
NPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASGEAINHYVKTIPSIFGGSADLSHSTMTDIKGEAVYAVESYAG
RNIYFGVREHAMGAAANGLALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAAL
RAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFNETKANIENLSKGAYVLTETNENPDVILIATGSEVS
LAASAKAKLEEDNVSVRIVAMPSWELFDRQSNEYKESVLPSSITKRVSLEMGVSLGWERYVGQEGKVLSIETFGASGTGA
EVMNLFGFTIENVVQITKNVLNS

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=671, Percent_Identity=26.2295081967213, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI4507521, Length=671, Percent_Identity=26.2295081967213, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI133778974, Length=662, Percent_Identity=25.6797583081571, Blast_Score=163, Evalue=6e-40,
Organism=Homo sapiens, GI225637459, Length=680, Percent_Identity=21.1764705882353, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI225637463, Length=571, Percent_Identity=22.0665499124343, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI225637461, Length=571, Percent_Identity=22.0665499124343, Blast_Score=122, Evalue=1e-27,
Organism=Escherichia coli, GI48994911, Length=658, Percent_Identity=48.0243161094225, Blast_Score=638, Evalue=0.0,
Organism=Escherichia coli, GI1788808, Length=666, Percent_Identity=46.996996996997, Blast_Score=624, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17539652, Length=666, Percent_Identity=26.1261261261261, Blast_Score=166, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6325331, Length=674, Percent_Identity=46.2908011869436, Blast_Score=592, Evalue=1e-170,
Organism=Saccharomyces cerevisiae, GI6319593, Length=672, Percent_Identity=44.4940476190476, Blast_Score=559, Evalue=1e-160,
Organism=Drosophila melanogaster, GI45551847, Length=584, Percent_Identity=29.6232876712329, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI45550715, Length=584, Percent_Identity=29.6232876712329, Blast_Score=205, Evalue=1e-52,
Organism=Drosophila melanogaster, GI24645119, Length=545, Percent_Identity=29.3577981651376, Blast_Score=188, Evalue=9e-48,
Organism=Drosophila melanogaster, GI24666278, Length=586, Percent_Identity=27.8156996587031, Blast_Score=185, Evalue=8e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 72157; Mature: 72026

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRD
CCCCHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
RFVLSAGHGSSLLYSLLHLAGYDVSIDDLKNFRKLNSKTPGHPEFGHTPGVEATTGPLGQ
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
GIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDLMEGVAYEAMSMAGHMKLGKL
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHCCEEECCE
IVLYDSNEISLDGELGIAFSEDIEKRAESVHWQYVRVEDGNDVDAITKAITLAKENTDQP
EEEECCCEEEECCCCCEEEHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCC
TLIEIRTIIGYGSPKVAGTNKAHGNPLGVEEATATKQVYGWDYEEDFFVPEEVTAHFNEL
EEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
KQKGIEKENEWNEQFNVYRESNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASG
HHHCCCCCCCCCHHHCEEECCCCCHHHHHHHHHCCCEEEEEHHHHCCCCCHHHHHHHCCC
EAINHYVKTIPSIFGGSADLSHSTMTDIKGEAVYAVESYAGRNIYFGVREHAMGAAANGL
HHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEECCCCCEEEEEEHHHHCCCCCCCE
ALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
EEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHH
LRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFNETKANIENLSKGAY
HHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCEE
VLTETNENPDVILIATGSEVSLAASAKAKLEEDNVSVRIVAMPSWELFDRQSNEYKESVL
EEEECCCCCCEEEEECCCCEEEEECCHHEECCCCEEEEEEEECCHHHHCCCCHHHHHHHC
PSSITKRVSLEMGVSLGWERYVGQEGKVLSIETFGASGTGAEVMNLFGFTIENVVQITKN
CHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
VLNS
HHCC
>Mature Secondary Structure 
TQNINQLAVNTIRTLSIDAINAANSGHPGLPMGAAPMAYALWANHLNHNPNHPKWFNRD
CCCHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
RFVLSAGHGSSLLYSLLHLAGYDVSIDDLKNFRKLNSKTPGHPEFGHTPGVEATTGPLGQ
EEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHH
GIANAVGMAMAEAHLAAKFNKDGHSIIDHNTYALVGDGDLMEGVAYEAMSMAGHMKLGKL
HHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEEECCHHHHHHHHHHHHHHCCEEECCE
IVLYDSNEISLDGELGIAFSEDIEKRAESVHWQYVRVEDGNDVDAITKAITLAKENTDQP
EEEECCCEEEECCCCCEEEHHHHHHHHHHCCEEEEEEECCCCHHHHHHHHHHHCCCCCCC
TLIEIRTIIGYGSPKVAGTNKAHGNPLGVEEATATKQVYGWDYEEDFFVPEEVTAHFNEL
EEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
KQKGIEKENEWNEQFNVYRESNPALADELEKAITGEVLIEAKDILSFDTEKTISTRVASG
HHHCCCCCCCCCHHHCEEECCCCCHHHHHHHHHCCCEEEEEHHHHCCCCCHHHHHHHCCC
EAINHYVKTIPSIFGGSADLSHSTMTDIKGEAVYAVESYAGRNIYFGVREHAMGAAANGL
HHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCEEEEEECCCCCEEEEEEHHHHCCCCCCCE
ALHGGVKPFVSTFFVFNDYLRPSIRLAALQKLPVTYVFTHDSIAVGEDGPTHEPIEHLAA
EEECCHHHHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEECCCEEECCCCCCHHHHHHHHH
LRAIPGLTVIRPSDANETASAWAYALQQTDGPVVLVLSRQNLPVFNETKANIENLSKGAY
HHHCCCCEEECCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCEE
VLTETNENPDVILIATGSEVSLAASAKAKLEEDNVSVRIVAMPSWELFDRQSNEYKESVL
EEEECCCCCCEEEEECCCCEEEEECCHHEECCCCEEEEEEEECCHHHHCCCCHHHHHHHC
PSSITKRVSLEMGVSLGWERYVGQEGKVLSIETFGASGTGAEVMNLFGFTIENVVQITKN
CHHHHHHHHHHHCCCCCHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
VLNS
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]