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The map label for this gene is glpD [H]

Identifier: 218234213

GI number: 218234213

Start: 1041527

End: 1043209

Strand: Direct

Name: glpD [H]

Synonym: BCB4264_A1067

Alternate gene names: 218234213

Gene position: 1041527-1043209 (Clockwise)

Preceding gene: 218235134

Following gene: 218231006

Centisome position: 19.22

GC content: 40.64

Gene sequence:

>1683_bases
ATGAAATTTTCAAGTAAACAACGTAAAGACGTATTAAACGGAGTAAATAAACAAGAGTTAGATGTGATCGTAATTGGTGG
AGGTATTACTGGTTCTGGTATTGCATTAGATGGAGCAACACGCGGGTTATCAACAATTGTGTTTGAAATGCAGGACTTTG
CAGCAGGTACATCAAGTCGTTCAACGAAGCTTGTACACGGTGGTCTACGTTATTTAAAACAACTTGAAGTGAAAATGGTA
GCAGAGGTGGGGAAAGAGCGTGCGATCGTATATGAGAACGGTCCCCATGTAACAACACCAGAGTGGATGTTACTTCCGTT
CCATACAGGCGGTACGTTCGGATCATTTAGTACATCAATTGGTCTTCGTGTATACGACTTCTTAGCAGGTGTAAAACGAA
GCGAGCGCAGAAAGATGTTTAACCGTGAAGAAACGCTAAACAAAGAGCCTCTTGTAAAAAAAGAAGGATTAAAAGGCGGC
GGTTACTACGTAGAATATCGTACAGACGATGCGCGTCTTACAATTGAAGTAATGAAAGAAGCAATTGAGCATGGTGCGAA
AGCTGTTAACTACGCAAAAGTAGACAGTTTCTTATATAAAGATGGAAATGTATGCGGTGTACGTGTAATCGATTTACTAG
ACGGTGAAGTGTACGAAGTTTACGGTAAGAAAATTGTAAACGCAGCTGGTCCTTGGGTAGATACACTTCGTGAAAAAGAT
AACTCGAAAAAAGGAAAAGTACTTCAGTTATCAAAAGGTGTTCACTTAGTAATTGATCAAAAACGTTTCCCATTAGGTCA
AGCGATTTACTTCGATACACCAGATAAACGTATGGTGTTCGCGATTCCTCGCGGCGGAAAAACATACGTAGGTACAACAG
ATACGTTCTATGATAAAGATGCAGCTGTACCACAAATGACGACAGAAGATCGCACATACATCATTAATGCGATTAACTAC
ATGTTCCCAAGTGTAAAAATTACGGAAAAAGACATCGAATCAAGCTGGGCTGGTGTACGTCCGTTAATTTATGAAGAAGG
TAAGAGTGCATCTGAAATTTCTCGTAAAGATGAAATTTGGACTTCTGAATCTGGTTTAATTACAATCGCAGGTGGTAAAT
TAACTGGATACCGCAAAATGGCTGAAATGGTAGTAGATTACGTAACGAACTTACTACAAAAAGAAGGCCATAGTGCATAT
CCGAAGAGTACAACGAAACATATGCCAATCTCTGGTGGACATGTAGATGGTTCACACGGATTCCCAGCATTCGTTGCGAA
AAAAGCTGGCGAAGGTACGAAATATGGTTTAACAACAGCACAAGCAGAAGAATTCGCGAAATTCTACGGCTCTAACGTTG
ACGTACTATTTGATTTAGCGAAAAAACATAAAGACGAAGCGAAAGAATACAACATGCCACTAGACGTTCTAATCCCGCTT
GTATACGCAATGGATTACGAAATGACAGCAAAACCAGTTGACTTCTTCGTACGCCGCAGAGGCGCTGTATTCTTCAACAT
CCACTGGGTATACGAGTGGAAAGAAGCAGTAATCAACTACATGGCTGCGAAACTAGGCTGGAGCAAAGAAGAGCAAATGA
AATACACAGCTGAATTAGAAAAAGCATTAACAGACGCTGTCATTCCTGTAGATCAACAAGAACAGGCAGCTGCGTTAGCG
TAA

Upstream 100 bases:

>100_bases
AATTCGGTAGGAGATTTGGAGAGACCACAACGCGCTATAGAGGCGAAATCTATAGCGGAGTTTGTGGTCTCTTTTTTCGT
TATCAAAGGGAGGAATTACC

Downstream 100 bases:

>100_bases
AATAGAGAACCACCTGAAGGGGAGCCTTTAGGTGGTTCTTTTTTTTATGGAATATTCTTCTAACTATATTGCATAACGAC
ATATGTTGTTATACGATGTA

Product: glycerol-3-phosphate dehydrogenase, aerobic

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 560

Protein sequence:

>560_residues
MKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSRSTKLVHGGLRYLKQLEVKMV
AEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSIGLRVYDFLAGVKRSERRKMFNREETLNKEPLVKKEGLKGG
GYYVEYRTDDARLTIEVMKEAIEHGAKAVNYAKVDSFLYKDGNVCGVRVIDLLDGEVYEVYGKKIVNAAGPWVDTLREKD
NSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKDAAVPQMTTEDRTYIINAINY
MFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIWTSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAY
PKSTTKHMPISGGHVDGSHGFPAFVAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEAKEYNMPLDVLIPL
VYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELEKALTDAVIPVDQQEQAAALA

Sequences:

>Translated_560_residues
MKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSRSTKLVHGGLRYLKQLEVKMV
AEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSIGLRVYDFLAGVKRSERRKMFNREETLNKEPLVKKEGLKGG
GYYVEYRTDDARLTIEVMKEAIEHGAKAVNYAKVDSFLYKDGNVCGVRVIDLLDGEVYEVYGKKIVNAAGPWVDTLREKD
NSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKDAAVPQMTTEDRTYIINAINY
MFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIWTSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAY
PKSTTKHMPISGGHVDGSHGFPAFVAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEAKEYNMPLDVLIPL
VYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELEKALTDAVIPVDQQEQAAALA
>Mature_560_residues
MKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSRSTKLVHGGLRYLKQLEVKMV
AEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSIGLRVYDFLAGVKRSERRKMFNREETLNKEPLVKKEGLKGG
GYYVEYRTDDARLTIEVMKEAIEHGAKAVNYAKVDSFLYKDGNVCGVRVIDLLDGEVYEVYGKKIVNAAGPWVDTLREKD
NSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKDAAVPQMTTEDRTYIINAINY
MFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIWTSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAY
PKSTTKHMPISGGHVDGSHGFPAFVAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEAKEYNMPLDVLIPL
VYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELEKALTDAVIPVDQQEQAAALA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=548, Percent_Identity=33.2116788321168, Blast_Score=261, Evalue=2e-69,
Organism=Homo sapiens, GI285002231, Length=548, Percent_Identity=33.2116788321168, Blast_Score=261, Evalue=2e-69,
Organism=Escherichia coli, GI2367226, Length=466, Percent_Identity=29.8283261802575, Blast_Score=165, Evalue=9e-42,
Organism=Escherichia coli, GI1788574, Length=371, Percent_Identity=26.6846361185984, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17509253, Length=574, Percent_Identity=32.5783972125435, Blast_Score=253, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI115534726, Length=542, Percent_Identity=32.1033210332103, Blast_Score=218, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6322036, Length=610, Percent_Identity=28.8524590163934, Blast_Score=214, Evalue=3e-56,
Organism=Drosophila melanogaster, GI161077125, Length=562, Percent_Identity=33.4519572953737, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24653942, Length=562, Percent_Identity=33.4519572953737, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24653944, Length=562, Percent_Identity=33.4519572953737, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI20130025, Length=562, Percent_Identity=33.4519572953737, Blast_Score=263, Evalue=3e-70,
Organism=Drosophila melanogaster, GI24586295, Length=558, Percent_Identity=28.3154121863799, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI19921278, Length=550, Percent_Identity=26.5454545454545, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI45550977, Length=401, Percent_Identity=24.1895261845387, Blast_Score=96, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 62479; Mature: 62479

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSR
CCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCC
STKLVHGGLRYLKQLEVKMVAEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSI
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHC
GLRVYDFLAGVKRSERRKMFNREETLNKEPLVKKEGLKGGGYYVEYRTDDARLTIEVMKE
CHHHHHHHHHCHHHHHHHHHCHHHHCCCCCCCHHCCCCCCCEEEEEECCCCEEEHHHHHH
AIEHGAKAVNYAKVDSFLYKDGNVCGVRVIDLLDGEVYEVYGKKIVNAAGPWVDTLREKD
HHHHHHHHCCHHHHHHHHCCCCCEEEEEEEEHHCCHHHHHHHHHHHHCCCCHHHHHHHCC
NSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKD
CCCCCCEEEECCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCEEECCCCCCCCCC
AAVPQMTTEDRTYIINAINYMFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIW
CCCCCCCCCCCEEEEEEHHHHCCCCEEEHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCE
TSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAYPKSTTKHMPISGGHVDGSHG
ECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
FPAFVAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEAKEYNMPLDVLIPL
CHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELE
HHHCCCCCCCCHHHHHHHCCCEEEEEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KALTDAVIPVDQQEQAAALA
HHHHHHCCCCCCCHHHHCCC
>Mature Secondary Structure
MKFSSKQRKDVLNGVNKQELDVIVIGGGITGSGIALDGATRGLSTIVFEMQDFAAGTSSR
CCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCC
STKLVHGGLRYLKQLEVKMVAEVGKERAIVYENGPHVTTPEWMLLPFHTGGTFGSFSTSI
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHC
GLRVYDFLAGVKRSERRKMFNREETLNKEPLVKKEGLKGGGYYVEYRTDDARLTIEVMKE
CHHHHHHHHHCHHHHHHHHHCHHHHCCCCCCCHHCCCCCCCEEEEEECCCCEEEHHHHHH
AIEHGAKAVNYAKVDSFLYKDGNVCGVRVIDLLDGEVYEVYGKKIVNAAGPWVDTLREKD
HHHHHHHHCCHHHHHHHHCCCCCEEEEEEEEHHCCHHHHHHHHHHHHCCCCHHHHHHHCC
NSKKGKVLQLSKGVHLVIDQKRFPLGQAIYFDTPDKRMVFAIPRGGKTYVGTTDTFYDKD
CCCCCCEEEECCCEEEEEECCCCCCCCEEEEECCCCEEEEEECCCCCEEECCCCCCCCCC
AAVPQMTTEDRTYIINAINYMFPSVKITEKDIESSWAGVRPLIYEEGKSASEISRKDEIW
CCCCCCCCCCCEEEEEEHHHHCCCCEEEHHHHHHCCCCCCCEEEECCCCHHHHHHHHCCE
TSESGLITIAGGKLTGYRKMAEMVVDYVTNLLQKEGHSAYPKSTTKHMPISGGHVDGSHG
ECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
FPAFVAKKAGEGTKYGLTTAQAEEFAKFYGSNVDVLFDLAKKHKDEAKEYNMPLDVLIPL
CHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VYAMDYEMTAKPVDFFVRRRGAVFFNIHWVYEWKEAVINYMAAKLGWSKEEQMKYTAELE
HHHCCCCCCCCHHHHHHHCCCEEEEEEEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHH
KALTDAVIPVDQQEQAAALA
HHHHHHCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2127799; 9579061; 9384377; 1809833 [H]