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The map label for this gene is adcA [H]

Identifier: 218234150

GI number: 218234150

Start: 1935341

End: 1936291

Strand: Reverse

Name: adcA [H]

Synonym: BCB4264_A2025

Alternate gene names: 218234150

Gene position: 1936291-1935341 (Counterclockwise)

Preceding gene: 218233239

Following gene: 218234692

Centisome position: 35.73

GC content: 33.12

Gene sequence:

>951_bases
ATGCCTAAAAGATTGACTATATTTTCATTCTTACTTATTTTTACCTTAATTTTCGCTGGCTGCTCAAATAAAAAAGAAAG
TAATGCCAAGAAAGATGGAAAGCTAACAGTTTATACAACGATTTTCCCACTTGCTGATTTCGCAAAGAAAATTGGTGGCG
ACTATGTAAATGTTGAAGCAATTTACCCACCTGGTGCAGATTCACATACATTTGAACCAAGTCAAAAACAAACAGTACAA
GTTGCAAAAGCCGATTTATTTGTTTATAACGGCGCTGAATTAGAACCATTTGCTGAAAAAATGGAAAAAACATTACAAAA
AGAAAATGTTAAAATTGTAAATGCATCTAAAGGTATTGAGCTTCGTGCTTCTACTGAAGAAGAGCATCATGATCATGGAG
ATGGCCATAAAGAAGATGAACATCATCACGATAAAGACCCACATGTTTGGTTAGATCCTACTCTAGCAATGAAACAAGCA
GAAAAAATTAAAAATGCACTTGTAGAATTACAACCTGAACATAAAAAAGAATTCGAAAAAAACTTTGCAGCACTTCAAAC
TAAATTTACTGATTTAGACGATGGATTTAAGGCAGCTGTAGCGAACGCAAAAACGAAAGAAATTTTAGTTTCTCATGCTG
CCTATGGTTACTGGGAACAACGATACGGCCTAAAACAAATTCCTATCGCTGGAATTTCAGCTTCTGATGAACCATCTCAA
AAGCAGCTTGCTGACATTACAAAAACAGTAAAAGAACATAATCTAAAATATATTTTATTCGAAACGTTCTCTACTCCAAA
AGTAGCATCCGTAATTCAAAAAGAAACTGGTACAAAAGTTTTACGCTTAAATCACTTAGCTACTATTTCTGAAGATGATG
CAAAAAATAATAAAGATTACTTCACTTTAATGGAAGAAAACGTAAATACATTGAAAGAAGCAACAAACTAA

Upstream 100 bases:

>100_bases
TCGCAAACTAAAACGTAATTATTCCGTTTTGTATTAAAATGATATTTTTCTTCTATAATTGGGGAAAATATATCCGTAAA
AAAGAAAAGAGGAGAACTTC

Downstream 100 bases:

>100_bases
TCCATTATATTTTCTAGGCAGCTGAATCTGTTATTCAGCTGCCTTTTTATGTATTTATCCTTGACTTGACCAAAATAACA
AGTAAAATTATCCATATTAG

Product: putative adhesion lipoprotein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MPKRLTIFSFLLIFTLIFAGCSNKKESNAKKDGKLTVYTTIFPLADFAKKIGGDYVNVEAIYPPGADSHTFEPSQKQTVQ
VAKADLFVYNGAELEPFAEKMEKTLQKENVKIVNASKGIELRASTEEEHHDHGDGHKEDEHHHDKDPHVWLDPTLAMKQA
EKIKNALVELQPEHKKEFEKNFAALQTKFTDLDDGFKAAVANAKTKEILVSHAAYGYWEQRYGLKQIPIAGISASDEPSQ
KQLADITKTVKEHNLKYILFETFSTPKVASVIQKETGTKVLRLNHLATISEDDAKNNKDYFTLMEENVNTLKEATN

Sequences:

>Translated_316_residues
MPKRLTIFSFLLIFTLIFAGCSNKKESNAKKDGKLTVYTTIFPLADFAKKIGGDYVNVEAIYPPGADSHTFEPSQKQTVQ
VAKADLFVYNGAELEPFAEKMEKTLQKENVKIVNASKGIELRASTEEEHHDHGDGHKEDEHHHDKDPHVWLDPTLAMKQA
EKIKNALVELQPEHKKEFEKNFAALQTKFTDLDDGFKAAVANAKTKEILVSHAAYGYWEQRYGLKQIPIAGISASDEPSQ
KQLADITKTVKEHNLKYILFETFSTPKVASVIQKETGTKVLRLNHLATISEDDAKNNKDYFTLMEENVNTLKEATN
>Mature_315_residues
PKRLTIFSFLLIFTLIFAGCSNKKESNAKKDGKLTVYTTIFPLADFAKKIGGDYVNVEAIYPPGADSHTFEPSQKQTVQV
AKADLFVYNGAELEPFAEKMEKTLQKENVKIVNASKGIELRASTEEEHHDHGDGHKEDEHHHDKDPHVWLDPTLAMKQAE
KIKNALVELQPEHKKEFEKNFAALQTKFTDLDDGFKAAVANAKTKEILVSHAAYGYWEQRYGLKQIPIAGISASDEPSQK
QLADITKTVKEHNLKYILFETFSTPKVASVIQKETGTKVLRLNHLATISEDDAKNNKDYFTLMEENVNTLKEATN

Specific function: Part of the ATP-driven transport system AdcABC for zinc. Required for transformability [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=273, Percent_Identity=24.5421245421245, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR012674
- InterPro:   IPR011038
- InterPro:   IPR006128
- InterPro:   IPR015304 [H]

Pfam domain/function: PF01297 SBP_bac_9; PF09223 YodA [H]

EC number: NA

Molecular weight: Translated: 35607; Mature: 35475

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKRLTIFSFLLIFTLIFAGCSNKKESNAKKDGKLTVYTTIFPLADFAKKIGGDYVNVEA
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCEEEEEE
IYPPGADSHTFEPSQKQTVQVAKADLFVYNGAELEPFAEKMEKTLQKENVKIVNASKGIE
ECCCCCCCCCCCCCHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEECCCCEE
LRASTEEEHHDHGDGHKEDEHHHDKDPHVWLDPTLAMKQAEKIKNALVELQPEHKKEFEK
EEECCCHHHCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NFAALQTKFTDLDDGFKAAVANAKTKEILVSHAAYGYWEQRYGLKQIPIAGISASDEPSQ
HHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHH
KQLADITKTVKEHNLKYILFETFSTPKVASVIQKETGTKVLRLNHLATISEDDAKNNKDY
HHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEHHEECCCCCCCCCCCE
FTLMEENVNTLKEATN
EEEHHHHHHHHHHCCC
>Mature Secondary Structure 
PKRLTIFSFLLIFTLIFAGCSNKKESNAKKDGKLTVYTTIFPLADFAKKIGGDYVNVEA
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCEEEEEE
IYPPGADSHTFEPSQKQTVQVAKADLFVYNGAELEPFAEKMEKTLQKENVKIVNASKGIE
ECCCCCCCCCCCCCHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHCCEEEEECCCCEE
LRASTEEEHHDHGDGHKEDEHHHDKDPHVWLDPTLAMKQAEKIKNALVELQPEHKKEFEK
EEECCCHHHCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NFAALQTKFTDLDDGFKAAVANAKTKEILVSHAAYGYWEQRYGLKQIPIAGISASDEPSQ
HHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCHH
KQLADITKTVKEHNLKYILFETFSTPKVASVIQKETGTKVLRLNHLATISEDDAKNNKDY
HHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHCCCEEEEEEHHEECCCCCCCCCCCE
FTLMEENVNTLKEATN
EEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11463916 [H]