Click here to switch to the map view.

The map label for this gene is namA [H]

Identifier: 218233239

GI number: 218233239

Start: 1937511

End: 1938548

Strand: Reverse

Name: namA [H]

Synonym: BCB4264_A2028

Alternate gene names: 218233239

Gene position: 1938548-1937511 (Counterclockwise)

Preceding gene: 218234727

Following gene: 218234150

Centisome position: 35.77

GC content: 39.6

Gene sequence:

>1038_bases
ATGAATTCCAAGCTTTTTTCACCTTATACAATTAAGAACGTTACACTAAAAAATCGTATCGTTATGTCGCCTATGTGTAT
GTATTCCTCGGGGAATGAGGATGGCAGCGTTACGAATTTTCATCTCATTCATTATGGAACTCGCGCTGCTGGCCAAGTAG
GTTTAGTTATGGTTGAAGCAACTGCGGTGTTAGCTGAAGGACGAATTTCTAACAAAGACTTAGGTATTTGGGATGACAAC
CTAATTGAAGGCTTACATAAAACGACTACTTTTATACATGATAACGGCGCAAAAGCTGCCATTCAACTCGCTCACGCCGG
AAGAAAAGCTGAATTAGATACGAATGCTTTCGCTCCTTCTGCAATTCCTTTTAATGATAAGATGAAGATACCAGTAGAAA
TGAATATACAGCAAATCAAAGAGACTATATTAGCTTTTCAGAGGGCCGCGTTACGTTCAAAACAAGCCGGATTTGATGTT
ATCGAATTACATGGCGCTCACGGTTACCTTATCAATGAATTCCTATCACCACTTACTAATAAACGAACGGATAAATACGG
CGGCTCACCTGAAAACCGCTATCGTTTCTTACGCGAAATTATCGACTCTGTAAATGAAGTTTGGGACGGACCAATATTCG
TTCGTATTTCAGCAAATGATTATCACCCTGACGGGCTAACGGTTCAAGATTATGTTCAGTATACAAAGTGGATGAAAGAA
CAGGGAATAGATTTAATAGATTGTAGTTCTGGCGCAGTTGTACCAGCACATATTGATGTGTATCCCGGTTATCAAGTACA
ATACGCCAAACATATTAAAGAGCATACTAAGATTGCAACTGGTGCAGTTGGATTGATTACGACTGGGTCACAAGCAGAGC
AAATTTTAAATAATAACGAAGCTGATTTAATTTTCATCGGACGTGAGTTACTTCGCAATCCGTACTTCCCGAGAATAGCG
GCCAATGAACTTGGCTTTGAATTGCAAGAACCATATCAATACAAGCGAGCGCCAGGGAAAATTCATACGAATAAATAA

Upstream 100 bases:

>100_bases
TGTAACACGAATATACAAAATTTTTCGTATAAGCGTTTTATTAGAGAAACAAAAAAGAGAATGGTAAAATATAAGAAAAT
TCAATCAAGGAGGCTATTTG

Downstream 100 bases:

>100_bases
AACCGAGAAGTCATTCTTCTCGGTTTTATTTATTCTATCGTTGTAATTTCATTTGAATTATAAGTATGGATACCCGATTC
TTCTCGCAGCGCGGTTATAT

Product: NADPH dehydrogenase NamA

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MNSKLFSPYTIKNVTLKNRIVMSPMCMYSSGNEDGSVTNFHLIHYGTRAAGQVGLVMVEATAVLAEGRISNKDLGIWDDN
LIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELDTNAFAPSAIPFNDKMKIPVEMNIQQIKETILAFQRAALRSKQAGFDV
IELHGAHGYLINEFLSPLTNKRTDKYGGSPENRYRFLREIIDSVNEVWDGPIFVRISANDYHPDGLTVQDYVQYTKWMKE
QGIDLIDCSSGAVVPAHIDVYPGYQVQYAKHIKEHTKIATGAVGLITTGSQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELQEPYQYKRAPGKIHTNK

Sequences:

>Translated_345_residues
MNSKLFSPYTIKNVTLKNRIVMSPMCMYSSGNEDGSVTNFHLIHYGTRAAGQVGLVMVEATAVLAEGRISNKDLGIWDDN
LIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELDTNAFAPSAIPFNDKMKIPVEMNIQQIKETILAFQRAALRSKQAGFDV
IELHGAHGYLINEFLSPLTNKRTDKYGGSPENRYRFLREIIDSVNEVWDGPIFVRISANDYHPDGLTVQDYVQYTKWMKE
QGIDLIDCSSGAVVPAHIDVYPGYQVQYAKHIKEHTKIATGAVGLITTGSQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELQEPYQYKRAPGKIHTNK
>Mature_345_residues
MNSKLFSPYTIKNVTLKNRIVMSPMCMYSSGNEDGSVTNFHLIHYGTRAAGQVGLVMVEATAVLAEGRISNKDLGIWDDN
LIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELDTNAFAPSAIPFNDKMKIPVEMNIQQIKETILAFQRAALRSKQAGFDV
IELHGAHGYLINEFLSPLTNKRTDKYGGSPENRYRFLREIIDSVNEVWDGPIFVRISANDYHPDGLTVQDYVQYTKWMKE
QGIDLIDCSSGAVVPAHIDVYPGYQVQYAKHIKEHTKIATGAVGLITTGSQAEQILNNNEADLIFIGRELLRNPYFPRIA
ANELGFELQEPYQYKRAPGKIHTNK

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=236, Percent_Identity=33.0508474576271, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1789463, Length=316, Percent_Identity=29.746835443038, Blast_Score=118, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17565138, Length=207, Percent_Identity=32.8502415458937, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=172, Percent_Identity=35.4651162790698, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17540738, Length=248, Percent_Identity=32.258064516129, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI72001454, Length=248, Percent_Identity=29.8387096774194, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559804, Length=173, Percent_Identity=34.6820809248555, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17564188, Length=248, Percent_Identity=28.6290322580645, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17566914, Length=245, Percent_Identity=28.9795918367347, Blast_Score=95, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6325086, Length=223, Percent_Identity=30.9417040358744, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6321973, Length=223, Percent_Identity=32.2869955156951, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 38567; Mature: 38567

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSKLFSPYTIKNVTLKNRIVMSPMCMYSSGNEDGSVTNFHLIHYGTRAAGQVGLVMVEA
CCCCCCCCEEEEEEEECCEEEECCEEEECCCCCCCCEEEEEEEEECCCCCCCEEEEEEEE
TAVLAEGRISNKDLGIWDDNLIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELDTNAFAPS
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCCCCCCCCC
AIPFNDKMKIPVEMNIQQIKETILAFQRAALRSKQAGFDVIELHGAHGYLINEFLSPLTN
CCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
KRTDKYGGSPENRYRFLREIIDSVNEVWDGPIFVRISANDYHPDGLTVQDYVQYTKWMKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QGIDLIDCSSGAVVPAHIDVYPGYQVQYAKHIKEHTKIATGAVGLITTGSQAEQILNNNE
CCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCC
ADLIFIGRELLRNPYFPRIAANELGFELQEPYQYKRAPGKIHTNK
CCEEEECHHHHCCCCCCCEEHHHCCCCCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MNSKLFSPYTIKNVTLKNRIVMSPMCMYSSGNEDGSVTNFHLIHYGTRAAGQVGLVMVEA
CCCCCCCCEEEEEEEECCEEEECCEEEECCCCCCCCEEEEEEEEECCCCCCCEEEEEEEE
TAVLAEGRISNKDLGIWDDNLIEGLHKTTTFIHDNGAKAAIQLAHAGRKAELDTNAFAPS
HHHHHCCCCCCCCCCCCCHHHHHHHHHHHEEEECCCCCEEEEEECCCCCCCCCCCCCCCC
AIPFNDKMKIPVEMNIQQIKETILAFQRAALRSKQAGFDVIELHGAHGYLINEFLSPLTN
CCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHC
KRTDKYGGSPENRYRFLREIIDSVNEVWDGPIFVRISANDYHPDGLTVQDYVQYTKWMKE
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHH
QGIDLIDCSSGAVVPAHIDVYPGYQVQYAKHIKEHTKIATGAVGLITTGSQAEQILNNNE
CCCCEEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCC
ADLIFIGRELLRNPYFPRIAANELGFELQEPYQYKRAPGKIHTNK
CCEEEECHHHHCCCCCCCEEHHHCCCCCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA