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The map label for this gene is dnaX [H]

Identifier: 218233931

GI number: 218233931

Start: 25518

End: 27206

Strand: Direct

Name: dnaX [H]

Synonym: BCB4264_A0024

Alternate gene names: 218233931

Gene position: 25518-27206 (Clockwise)

Preceding gene: 218234516

Following gene: 218235146

Centisome position: 0.47

GC content: 38.9

Gene sequence:

>1689_bases
GTGTCATACCAAGCGTTATACCGAACATGGAGACCGCAAAAGTTCGAAGATGTAGTCGGTCAAAAGCACGTGACAAAAAC
GTTGCAAAATGCCCTTCTTCAAGAGAAAGTTTCACATGCTTATTTATTTTCTGGCCCGAGGGGAACAGGAAAAACGACAA
TTGCAAAAGTATTTGCAAAAGCAATTAACTGTGAACATGCTCCGGTAGCTGAACCTTGTAATGAATGTCCTTCTTGTTTA
GGAATCACACAAGGATCCATTTCAGATGTATTAGAAATTGATGCGGCTTCAAATAACGGTGTAGATGAAATTCGAGATAT
TAGAGATAAAGTAAAATATGCTCCAAGTGCTGTAGAATATAAAGTATACATTATTGATGAAGTTCACATGCTTTCTATGG
GTGCATTCAATGCGCTTTTAAAAACCTTAGAAGAGCCGCCAGGACATGTTATCTTTATTTTGGCGACAACAGAACCTCAT
AAGATCCCACCTACAATCATTTCACGTTGTCAGCGCTTTGAATTCCGAAAAATATCAGTGAATGATATTGTTGAGAGATT
ATCAACGGTCGTGACAAATGAAGGTACGCAAGTGGAAGGTGAAGCATTACAAATTGTTGCGCGTGCTGCCGAAGGTGGTA
TGCGTGACGCGCTTAGTCTTATTGATCAGGCTATATCTTATAGTGATGAGATTGTTACGACAGAAGATGTATTGGCCGTA
ACAGGATCTGTTTCTCAGCAATACTTAGGCAATTTAGTAGAGTGCATACGTGAAAATGATGTATCAAGAGCATTGCAAAT
CATAGATGAAATGATGAGTAAAGGGAAGGATCCAGTTCGTTTTATGGAGGATTTCATTTACTATTATCGTGATATGCTTT
TATATCAAACTTCACCGCAACTAGAACATATGTTGGAACGAGTAATTGTAGATGATCAATTCCGTAAGTTGAGTGAAGAA
ATGCAACCGGAAGTGATCTATGAGATTATTCATACCCTTAGTAAGGGACAACAGGAAATGAAGTGGACAAATCATCCGCG
TATTTTCTTAGAAGTTGTTATGGTGCAATTGTGTCAACAGTTTATGATGCAAGCAAATGGTACAGATCGTTTGCAAGCAA
TTATGAACAGGATGCAGCAACTGGAGAAAGAGTTAGAGCAAGTCAAAAAGAACGGTGTGCCAGCTGGTGTACAACAGGAA
GTAAGAGAGACACGCGCAACACCAAAACCGGTACGAACAGGAAGTATGAAAATTCCTGTCGGACGTGTAAATGAAGTATT
AAAACAAGCGAAGCGTCAAGATTTAGAACAATTAAAAGCTGTATGGGGTGAGTTGTTAGGAAGACTCAAATCATATAACA
AAGTAGCGTTTGCCGTTTTACTTGAAAATAGTGAACCAGTGGCAGCTTCAGATGACACTTACGTTTTAGCATTTCAATAT
GAGATTCACTGTAAGATGGCGAGCGAAAATCGAGAAGCTATGGATACAGTAGAACAAGCTTTATTTGAATTGCTAAGTAA
AAGGTTAAATATGATTGCCATTCCAAAAAGTGAATGGGGTAAAATCCGTGAAGACTTTTTACAACGTGAAGGCGGAGAGT
CTGAAGAAAGCCCGGAGAAAAAGGAAGACCCTCTTATAGAAGAGGCAGTGAAGTTAGTAGGGCAAGAACTCATTGAAATA
AAAGAGTAA

Upstream 100 bases:

>100_bases
ACAAAGGTGAGTTTTTTGTATAGAAAATAACTTTTGGAATCTATAAACAGAATGGGTTATAATAAATGAGATAATAACCT
TTGAGGGAGGCCGTATTTTC

Downstream 100 bases:

>100_bases
TAATAATTAGGAGGAATTAATTATGATGCGTGGCGGAATGGGAAATATGAATAACATGATGAAACAAATGCAAAAGATGC
AAAAGGACATGGCGAAAGCA

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL
GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH
KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEGEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV
TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDQFRKLSEE
MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGTDRLQAIMNRMQQLEKELEQVKKNGVPAGVQQE
VRETRATPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAVLLENSEPVAASDDTYVLAFQY
EIHCKMASENREAMDTVEQALFELLSKRLNMIAIPKSEWGKIREDFLQREGGESEESPEKKEDPLIEEAVKLVGQELIEI
KE

Sequences:

>Translated_562_residues
MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCL
GITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPH
KIPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEGEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV
TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDQFRKLSEE
MQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGTDRLQAIMNRMQQLEKELEQVKKNGVPAGVQQE
VRETRATPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAVLLENSEPVAASDDTYVLAFQY
EIHCKMASENREAMDTVEQALFELLSKRLNMIAIPKSEWGKIREDFLQREGGESEESPEKKEDPLIEEAVKLVGQELIEI
KE
>Mature_561_residues
SYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAKAINCEHAPVAEPCNECPSCLG
ITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEYKVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHK
IPPTIISRCQRFEFRKISVNDIVERLSTVVTNEGTQVEGEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAVT
GSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQLEHMLERVIVDDQFRKLSEEM
QPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQFMMQANGTDRLQAIMNRMQQLEKELEQVKKNGVPAGVQQEV
RETRATPKPVRTGSMKIPVGRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAVLLENSEPVAASDDTYVLAFQYE
IHCKMASENREAMDTVEQALFELLSKRLNMIAIPKSEWGKIREDFLQREGGESEESPEKKEDPLIEEAVKLVGQELIEIK
E

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=266, Percent_Identity=26.6917293233083, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI194306571, Length=266, Percent_Identity=26.6917293233083, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI194306567, Length=266, Percent_Identity=26.6917293233083, Blast_Score=92, Evalue=1e-18,
Organism=Homo sapiens, GI31563534, Length=285, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4506491, Length=368, Percent_Identity=20.6521739130435, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI31881687, Length=368, Percent_Identity=20.6521739130435, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI194306569, Length=186, Percent_Identity=27.9569892473118, Blast_Score=70, Evalue=6e-12,
Organism=Escherichia coli, GI1786676, Length=356, Percent_Identity=42.9775280898876, Blast_Score=296, Evalue=2e-81,
Organism=Escherichia coli, GI1787119, Length=306, Percent_Identity=22.8758169934641, Blast_Score=67, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71986063, Length=295, Percent_Identity=24.0677966101695, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17554730, Length=222, Percent_Identity=26.5765765765766, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17541988, Length=237, Percent_Identity=28.2700421940928, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6324039, Length=309, Percent_Identity=25.2427184466019, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322528, Length=309, Percent_Identity=22.9773462783171, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324478, Length=239, Percent_Identity=25.1046025104602, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI18859927, Length=290, Percent_Identity=22.7586206896552, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17647857, Length=284, Percent_Identity=27.112676056338, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19921076, Length=226, Percent_Identity=24.7787610619469, Blast_Score=82, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 63791; Mature: 63660

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAK
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
AINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEY
HHCCCCCCCCCHHHHCHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEE
KVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISV
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCH
NDIVERLSTVVTNEGTQVEGEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHH
LEHMLERVIVDDQFRKLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQ
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
FMMQANGTDRLQAIMNRMQQLEKELEQVKKNGVPAGVQQEVRETRATPKPVRTGSMKIPV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCEECCH
GRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAVLLENSEPVAASDDTYVLAFQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCEEEEEEE
EIHCKMASENREAMDTVEQALFELLSKRLNMIAIPKSEWGKIREDFLQREGGESEESPEK
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCC
KEDPLIEEAVKLVGQELIEIKE
CCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SYQALYRTWRPQKFEDVVGQKHVTKTLQNALLQEKVSHAYLFSGPRGTGKTTIAKVFAK
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHH
AINCEHAPVAEPCNECPSCLGITQGSISDVLEIDAASNNGVDEIRDIRDKVKYAPSAVEY
HHCCCCCCCCCHHHHCHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEE
KVYIIDEVHMLSMGAFNALLKTLEEPPGHVIFILATTEPHKIPPTIISRCQRFEFRKISV
EEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCH
NDIVERLSTVVTNEGTQVEGEALQIVARAAEGGMRDALSLIDQAISYSDEIVTTEDVLAV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCHHHHHHH
TGSVSQQYLGNLVECIRENDVSRALQIIDEMMSKGKDPVRFMEDFIYYYRDMLLYQTSPQ
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHH
LEHMLERVIVDDQFRKLSEEMQPEVIYEIIHTLSKGQQEMKWTNHPRIFLEVVMVQLCQQ
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHH
FMMQANGTDRLQAIMNRMQQLEKELEQVKKNGVPAGVQQEVRETRATPKPVRTGSMKIPV
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCEECCH
GRVNEVLKQAKRQDLEQLKAVWGELLGRLKSYNKVAFAVLLENSEPVAASDDTYVLAFQY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCEEEEEEE
EIHCKMASENREAMDTVEQALFELLSKRLNMIAIPKSEWGKIREDFLQREGGESEESPEK
EEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCC
KEDPLIEEAVKLVGQELIEIKE
CCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]