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The map label for this gene is tadA [H]

Identifier: 218234516

GI number: 218234516

Start: 24541

End: 25041

Strand: Direct

Name: tadA [H]

Synonym: BCB4264_A0022

Alternate gene names: 218234516

Gene position: 24541-25041 (Clockwise)

Preceding gene: 218230771

Following gene: 218233931

Centisome position: 0.45

GC content: 37.92

Gene sequence:

>501_bases
ATGGAACAAGATCAAGATATTTATTTTATGCAATTAGCGATAGAAGAAGCTAAAAAGGCAGAGGAAATACAGGAAGTACC
AATTGGAGCAGTTATAGTGTTAGATGGTGAGGTAATTAGTGTTGCCCATAATTTAAGGGAAACTGAGCAAAGATCAATAG
CTCATGCTGAGTTGCTAGCGATAGATGATGCATGTAAAAAATTAGGGACATGGCGTTTAGAAGATGCAACATTGTATGTA
ACATTAGAACCTTGCCCAATGTGTGCGGGTGGAATTGTTTTATCACGAGTGAAGCGAGTTGTATATGGTGCAAGTGATCC
GAAGGGCGGATGTGCAGGGACATTGATGAATCTTTTAACGGATGACCGCTTCAATCATCAATGTGAAGTAGTATCTGGTG
TACTAGAGGAAGAATGCGGTACGTTGTTAACAAACTTTTTTAGAGAGCTTCGTAAAAAAAGAAAAGCAATAAAAAAATTA
GAGAAGAATACTGGGAACTAA

Upstream 100 bases:

>100_bases
CCTCTCTTTTTTCTTTTAGGGTGGATTGAATTTGTAAAAGTTATCCCCTGTGTAGTAAATGGAAATAAGTGTACTTTATT
TGTAATGAAAGGACTATGTT

Downstream 100 bases:

>100_bases
CGTATTTGCATTTTCTAAAGAAACAAGTTATACTGATAATGCCTTTAATGAAGGCAACCGAATATTGGTTTTAACTTTGC
CGTGCTAAGCGGGGAGGTAG

Product: cytidine/deoxycytidylate deaminase zinc-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MEQDQDIYFMQLAIEEAKKAEEIQEVPIGAVIVLDGEVISVAHNLRETEQRSIAHAELLAIDDACKKLGTWRLEDATLYV
TLEPCPMCAGGIVLSRVKRVVYGASDPKGGCAGTLMNLLTDDRFNHQCEVVSGVLEEECGTLLTNFFRELRKKRKAIKKL
EKNTGN

Sequences:

>Translated_166_residues
MEQDQDIYFMQLAIEEAKKAEEIQEVPIGAVIVLDGEVISVAHNLRETEQRSIAHAELLAIDDACKKLGTWRLEDATLYV
TLEPCPMCAGGIVLSRVKRVVYGASDPKGGCAGTLMNLLTDDRFNHQCEVVSGVLEEECGTLLTNFFRELRKKRKAIKKL
EKNTGN
>Mature_166_residues
MEQDQDIYFMQLAIEEAKKAEEIQEVPIGAVIVLDGEVISVAHNLRETEQRSIAHAELLAIDDACKKLGTWRLEDATLYV
TLEPCPMCAGGIVLSRVKRVVYGASDPKGGCAGTLMNLLTDDRFNHQCEVVSGVLEEECGTLLTNFFRELRKKRKAIKKL
EKNTGN

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=151, Percent_Identity=33.7748344370861, Blast_Score=85, Evalue=4e-17,
Organism=Escherichia coli, GI145693172, Length=157, Percent_Identity=45.2229299363057, Blast_Score=142, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=46.9387755102041, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17541138, Length=162, Percent_Identity=30.8641975308642, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17555996, Length=98, Percent_Identity=39.7959183673469, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=178, Percent_Identity=29.2134831460674, Blast_Score=73, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325319, Length=105, Percent_Identity=34.2857142857143, Blast_Score=64, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=29.4520547945205, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18466; Mature: 18466

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQDQDIYFMQLAIEEAKKAEEIQEVPIGAVIVLDGEVISVAHNLRETEQRSIAHAELLA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
IDDACKKLGTWRLEDATLYVTLEPCPMCAGGIVLSRVKRVVYGASDPKGGCAGTLMNLLT
HHHHHHHHCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DDRFNHQCEVVSGVLEEECGTLLTNFFRELRKKRKAIKKLEKNTGN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MEQDQDIYFMQLAIEEAKKAEEIQEVPIGAVIVLDGEVISVAHNLRETEQRSIAHAELLA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHH
IDDACKKLGTWRLEDATLYVTLEPCPMCAGGIVLSRVKRVVYGASDPKGGCAGTLMNLLT
HHHHHHHHCCEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DDRFNHQCEVVSGVLEEECGTLLTNFFRELRKKRKAIKKLEKNTGN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]