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The map label for this gene is rnhB [H]

Identifier: 218233890

GI number: 218233890

Start: 3858475

End: 3859248

Strand: Reverse

Name: rnhB [H]

Synonym: BCB4264_A3935

Alternate gene names: 218233890

Gene position: 3859248-3858475 (Counterclockwise)

Preceding gene: 218236121

Following gene: 218234588

Centisome position: 71.22

GC content: 36.82

Gene sequence:

>774_bases
ATGCAAACTATGACGATAAAAGAAGCGGAAAATGTATTGAAAGAAATTATGAATGAAGAAGATGATCGCTTTCAACTGTT
AATGAAAGATGATCGAAAAGGTGTTCAAAAGCTCGTTTTGAAGTGGTATAAACAAAAAGAGTTAGAACAGAAAGAAAAAG
AGAAGTTTTTTGAAATGTCCAAGTATGAAAATGCTTTGCGTGAAAAAGGGATCACATATATCGCGGGTATTGATGAAGTA
GGGCGTGGGCCATTGGCTGGGCCTGTTGTGACGGCAGCTGTCGTTCTTCCTGAGGATTTTTATATTCCAGGGTTAAATGA
CTCGAAAAAGTTGAGTGAAGCGAAACGTGAGCGTTTTTATGATGAAATAAAAGTACAAGCAATTGCAATTGGAGTAGGAA
TTGTATCACCGCAAGTTATTGATGATATTAATATTTACCAAGCAACGAAACAAGCGATGTTAGATGCAGTTGCAAATTTA
TCTTGTACACCCCAACATTTATTAATTGATGCGATGAAGCTTCCTACACCAATTCCGCAAACATCAATTATTAAAGGTGA
TGCGAAAAGTGTTTCGATTTCAGCAGCATCCATTATAGCAAAAGTAACGAGAGATCGTATGATGAAAGAACTGGGAGAGA
AGTATCCTGAATATGGATTTGAGCAACATATGGGATATGGCACAAAGCAACATTTAGAGGCAATTGAAGTGCATGGAGTA
CTAGATGAACACCGCAAGTCATTCGCACCAATTAAAGATATGATTCAAAAATAA

Upstream 100 bases:

>100_bases
TTGGAGAGCAAGTGGAAGATGTGGAAAAAATAGAAGAAGTATAAGACGTGCGTTTGTGCGTCTTTTCTTTTTGGATATGT
TTAAAAAGGAGCTTGTATAA

Downstream 100 bases:

>100_bases
GCTGTAAATATACAGCTTATTTTTTTATTTTGGCATATAAACATTACTATTTTCGAAAAAGAATAAAGCGATTTCAGTTT
TCTGACACTTTATTGTAGAC

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII [H]

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MQTMTIKEAENVLKEIMNEEDDRFQLLMKDDRKGVQKLVLKWYKQKELEQKEKEKFFEMSKYENALREKGITYIAGIDEV
GRGPLAGPVVTAAVVLPEDFYIPGLNDSKKLSEAKRERFYDEIKVQAIAIGVGIVSPQVIDDINIYQATKQAMLDAVANL
SCTPQHLLIDAMKLPTPIPQTSIIKGDAKSVSISAASIIAKVTRDRMMKELGEKYPEYGFEQHMGYGTKQHLEAIEVHGV
LDEHRKSFAPIKDMIQK

Sequences:

>Translated_257_residues
MQTMTIKEAENVLKEIMNEEDDRFQLLMKDDRKGVQKLVLKWYKQKELEQKEKEKFFEMSKYENALREKGITYIAGIDEV
GRGPLAGPVVTAAVVLPEDFYIPGLNDSKKLSEAKRERFYDEIKVQAIAIGVGIVSPQVIDDINIYQATKQAMLDAVANL
SCTPQHLLIDAMKLPTPIPQTSIIKGDAKSVSISAASIIAKVTRDRMMKELGEKYPEYGFEQHMGYGTKQHLEAIEVHGV
LDEHRKSFAPIKDMIQK
>Mature_257_residues
MQTMTIKEAENVLKEIMNEEDDRFQLLMKDDRKGVQKLVLKWYKQKELEQKEKEKFFEMSKYENALREKGITYIAGIDEV
GRGPLAGPVVTAAVVLPEDFYIPGLNDSKKLSEAKRERFYDEIKVQAIAIGVGIVSPQVIDDINIYQATKQAMLDAVANL
SCTPQHLLIDAMKLPTPIPQTSIIKGDAKSVSISAASIIAKVTRDRMMKELGEKYPEYGFEQHMGYGTKQHLEAIEVHGV
LDEHRKSFAPIKDMIQK

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family [H]

Homologues:

Organism=Escherichia coli, GI1786380, Length=180, Percent_Identity=51.6666666666667, Blast_Score=182, Evalue=2e-47,
Organism=Caenorhabditis elegans, GI17536263, Length=241, Percent_Identity=31.5352697095436, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337 [H]

Pfam domain/function: PF01351 RNase_HII [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 29101; Mature: 29101

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTMTIKEAENVLKEIMNEEDDRFQLLMKDDRKGVQKLVLKWYKQKELEQKEKEKFFEMS
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYENALREKGITYIAGIDEVGRGPLAGPVVTAAVVLPEDFYIPGLNDSKKLSEAKRERFY
HHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
DEIKVQAIAIGVGIVSPQVIDDINIYQATKQAMLDAVANLSCTPQHLLIDAMKLPTPIPQ
HHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
TSIIKGDAKSVSISAASIIAKVTRDRMMKELGEKYPEYGFEQHMGYGTKQHLEAIEVHGV
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHH
LDEHRKSFAPIKDMIQK
HHHHHHHCCCHHHHHCC
>Mature Secondary Structure
MQTMTIKEAENVLKEIMNEEDDRFQLLMKDDRKGVQKLVLKWYKQKELEQKEKEKFFEMS
CCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KYENALREKGITYIAGIDEVGRGPLAGPVVTAAVVLPEDFYIPGLNDSKKLSEAKRERFY
HHHHHHHHCCCEEEECCHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
DEIKVQAIAIGVGIVSPQVIDDINIYQATKQAMLDAVANLSCTPQHLLIDAMKLPTPIPQ
HHHHHHHHEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
TSIIKGDAKSVSISAASIIAKVTRDRMMKELGEKYPEYGFEQHMGYGTKQHLEAIEVHGV
CCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHH
LDEHRKSFAPIKDMIQK
HHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA