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The map label for this gene is gntK2 [H]

Identifier: 218233576

GI number: 218233576

Start: 3259051

End: 3260592

Strand: Reverse

Name: gntK2 [H]

Synonym: BCB4264_A3384

Alternate gene names: 218233576

Gene position: 3260592-3259051 (Counterclockwise)

Preceding gene: 218232976

Following gene: 218231889

Centisome position: 60.17

GC content: 37.42

Gene sequence:

>1542_bases
ATGGTGAGCTCAAAATATATGATTGGTGTAGACATTGGGACAACTAGTACAAAATCAGTTCTATTTTCTACTGATGGATC
TGTTATTGCTAGTCATGGAATTGAATATCCTTTATATTCTCCTACGCCTGAAACAGCAGAACAAGACCCAGAAGAAATTT
TTCGTGCAGTAATACATACGATTAAAGAAACTGTACGATCAAGTAGTGTACAGCCAAGTGATATTCTTTGTGTCTCTTTT
AGTTCGGCAATGCATAGTATCATTGCTGTAGATGAAAAGGGAAAGCCGTTAACGAGATGTATCACTTGGGCAGATAATAG
AAGTGCAAGCTGGGCGGAGAAAATAAAGAATGATATGAATGGTCATGAAATTTACCTTCGTACTGGGACACCAATTCATC
CGATGTCACCACTTTCGAAATTAGTTTGGCTACAGAATGAGAAGGCAGAGTTATTCGCAAAAAGTTATAAATTCATTTCT
ATTAAAGAATATGTTTTTTATAAGTTATATAAAGAGTATGTAATTGATTATTCTATAGCATCAGCAACAGGGATGTTTAA
TTTAAAATCTTTAAAATGGGATGAAGAGGCTTTATATGTTGCGGGAATTACAGATGAAAAGCTTTCAAAGCTTGTTCCAA
CAACGCACAGTTTAACAGGATTAGATGAAGAGCTTGCCAAAGAGATGAATGTACCTGTTTCTACGCCTTTTGTAGTAGGA
GCGAGTGATGGAGTACTATCTAATTTAGGGGTAAATGCAATAGATCCTGGCGTTGTGGCTGTTACAATTGGTACAAGCGG
TGCGATTCGTGCTGTAACAAATCGTCCTGTAACAGATCCAAAAGGGAGAATCTTTTGTTATGCGTTAACTGAAGACCATT
GGGTAATCGGTGGTCCAGTTAATAACGGTGGTATGATTTTCAGATGGGCTCGTGACCAATTGGGTACTTCAGAGATTGAA
CTTGCGAAGCGTTTAGGAAAAGATCCATATGAAGTACTTACTGAAATAGCAGCAAAAGTGAATCCTGGATCTGACGGTTT
ATTATTTCACCCGTATTTAGCAGGGGAAAGAGCTCCTTTATGGAATGCAAATGCACGAGGATCTTTCTTTGGACTCGGAT
TGCATCATAAGAAAGAACATCTGATCCGTGCTGTTTTAGAAGGAGTAATTTATAACTTATATACAGTTCTTCTCGCTTTA
AAAGAGCTAATTGGTGAACCGAAAAAAATTCAAGCGACAGGTGGTTTTGCAAGATCGGAACTTTGGAGACAGATGATGGC
AGATATTTTCCATCAAGACGTATATGTTCCGGAAAGTTTTGAAAGTTCTTGCTTAGGAGCTGCAATCCTGGGTTTATATA
GTTTAGGTGAAATAGATACGTTGCATGTAGTTTCTGAAATGGTAGGTGCAGATTTTCATCATGAGCCAAATATGGAAAGT
GTGGAAAAATATAAAGATTTAACGCCAATCTATATCCGTTTGTCCCGTCAATTGGAAGAAGAATATGAAAGTATAGCAGC
GTATCAAAAAAAGTGGGTTTAA

Upstream 100 bases:

>100_bases
GTTTCTATTTAGATAATTGTGGCATACAACGTTATCAATAGATAAAAGGAATGTATTTTTATGGTGGGATACTGTAACAA
TTTTTTGTTAGGAGGAAGAA

Downstream 100 bases:

>100_bases
AAGCTATTTACCAAGAAAATATGGTAACGTATAAAGAGGTACTCCGATTTTTTAGGATACTCTTTCAACATAAAATATTT
TAAGAAGCATGATGAACGAA

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVRSSSVQPSDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEKAELFAKSYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLKSLKWDEEALYVAGITDEKLSKLVPTTHSLTGLDEELAKEMNVPVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEIDTLHVVSEMVGADFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV

Sequences:

>Translated_513_residues
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVRSSSVQPSDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEKAELFAKSYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLKSLKWDEEALYVAGITDEKLSKLVPTTHSLTGLDEELAKEMNVPVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEIDTLHVVSEMVGADFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV
>Mature_513_residues
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHTIKETVRSSSVQPSDILCVSF
SSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMNGHEIYLRTGTPIHPMSPLSKLVWLQNEKAELFAKSYKFIS
IKEYVFYKLYKEYVIDYSIASATGMFNLKSLKWDEEALYVAGITDEKLSKLVPTTHSLTGLDEELAKEMNVPVSTPFVVG
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPVNNGGMIFRWARDQLGTSEIE
LAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPLWNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLAL
KELIGEPKKIQATGGFARSELWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEIDTLHVVSEMVGADFHHEPNMES
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI189409120, Length=462, Percent_Identity=27.7056277056277, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI4504007, Length=462, Percent_Identity=27.7056277056277, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI88196792, Length=484, Percent_Identity=26.2396694214876, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI42794763, Length=472, Percent_Identity=26.9067796610169, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI41393575, Length=453, Percent_Identity=26.4900662251656, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1789987, Length=494, Percent_Identity=27.3279352226721, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1787789, Length=501, Percent_Identity=27.7445109780439, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1790361, Length=497, Percent_Identity=26.3581488933602, Blast_Score=155, Evalue=8e-39,
Organism=Escherichia coli, GI1790005, Length=494, Percent_Identity=22.8744939271255, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789168, Length=476, Percent_Identity=21.6386554621849, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1789138, Length=475, Percent_Identity=23.3684210526316, Blast_Score=92, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17535599, Length=459, Percent_Identity=25.2723311546841, Blast_Score=120, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321755, Length=503, Percent_Identity=25.6461232604374, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24655555, Length=475, Percent_Identity=25.2631578947368, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24655560, Length=475, Percent_Identity=25.2631578947368, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24655570, Length=475, Percent_Identity=25.2631578947368, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24655574, Length=475, Percent_Identity=25.2631578947368, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24655565, Length=475, Percent_Identity=25.2631578947368, Blast_Score=125, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24656367, Length=549, Percent_Identity=22.5865209471767, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21357867, Length=562, Percent_Identity=22.4199288256228, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17864214, Length=479, Percent_Identity=24.4258872651357, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24654573, Length=423, Percent_Identity=23.8770685579196, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24657106, Length=561, Percent_Identity=23.5294117647059, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24657102, Length=561, Percent_Identity=23.5294117647059, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24656372, Length=393, Percent_Identity=21.6284987277354, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 56925; Mature: 56925

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHT
CCCCCEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IKETVRSSSVQPSDILCVSFSSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMN
HHHHHHHCCCCCCCEEEEEHHHHHHHEEEECCCCCCHHHEEEECCCCCHHHHHHHHCCCC
GHEIYLRTGTPIHPMSPLSKLVWLQNEKAELFAKSYKFISIKEYVFYKLYKEYVIDYSIA
CCEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHH
SATGMFNLKSLKWDEEALYVAGITDEKLSKLVPTTHSLTGLDEELAKEMNVPVSTPFVVG
HHCCCEEECCCCCCCCEEEEECCCHHHHHHHCCCCCHHCCCHHHHHHHCCCCCCCCEEEE
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPV
CCCCHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECEE
NNGGMIFRWARDQLGTSEIELAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPL
CCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCC
WNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLALKELIGEPKKIQATGGFARSE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
LWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEIDTLHVVSEMVGADFHHEPNMES
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHH
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSSKYMIGVDIGTTSTKSVLFSTDGSVIASHGIEYPLYSPTPETAEQDPEEIFRAVIHT
CCCCCEEEEEEECCCCCCEEEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IKETVRSSSVQPSDILCVSFSSAMHSIIAVDEKGKPLTRCITWADNRSASWAEKIKNDMN
HHHHHHHCCCCCCCEEEEEHHHHHHHEEEECCCCCCHHHEEEECCCCCHHHHHHHHCCCC
GHEIYLRTGTPIHPMSPLSKLVWLQNEKAELFAKSYKFISIKEYVFYKLYKEYVIDYSIA
CCEEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHH
SATGMFNLKSLKWDEEALYVAGITDEKLSKLVPTTHSLTGLDEELAKEMNVPVSTPFVVG
HHCCCEEECCCCCCCCEEEEECCCHHHHHHHCCCCCHHCCCHHHHHHHCCCCCCCCEEEE
ASDGVLSNLGVNAIDPGVVAVTIGTSGAIRAVTNRPVTDPKGRIFCYALTEDHWVIGGPV
CCCCHHHHCCCCCCCCCEEEEEECCCCCEEEECCCCCCCCCCCEEEEEECCCCEEEECEE
NNGGMIFRWARDQLGTSEIELAKRLGKDPYEVLTEIAAKVNPGSDGLLFHPYLAGERAPL
CCCCEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCC
WNANARGSFFGLGLHHKKEHLIRAVLEGVIYNLYTVLLALKELIGEPKKIQATGGFARSE
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHH
LWRQMMADIFHQDVYVPESFESSCLGAAILGLYSLGEIDTLHVVSEMVGADFHHEPNMES
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHH
VEKYKDLTPIYIRLSRQLEEEYESIAAYQKKWV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]