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The map label for this gene is gntP2 [H]

Identifier: 218232976

GI number: 218232976

Start: 3260702

End: 3262027

Strand: Reverse

Name: gntP2 [H]

Synonym: BCB4264_A3385

Alternate gene names: 218232976

Gene position: 3262027-3260702 (Counterclockwise)

Preceding gene: 218234004

Following gene: 218233576

Centisome position: 60.2

GC content: 36.27

Gene sequence:

>1326_bases
ATGAATATGTACCTTTTAATGATTACATTATTATCAATCGTAATTGTTATTTTAGGGGTGTCGTGGTGGAGATGGCATGC
GTTTATTAGTTTAACGGTTGCAAGTTTGTTTTTAGCAATTATGTCTGGAATGCCAATGGATAAAATAGTGAGTGCTTATG
AAACAGGAGTGGGGAGTGTTCTAGGGCATTTAGTAGGTATTTTAGTATTAGGTACAATTTTAGGGAAAATGATGGCAGAG
TCAGGTGCTGGAATGCAAGTGGCAGAGTTCTTTATTAAATCCTTTGGGATAAAAAACTTACCATGGGCTATGTTAATTGC
AGGTTTTATTATTGGAATCCCGGTGTTTTTTGAAGTAGGCATTTTAATATTACTGCCGTTAGTAATTTCAATTCATAAAA
CAACGAAACAAAATATTTTATTAATAGCATTACCAGCAATTGCTGGGCTATCTGTCGTGCACGGTCTTGTTCCTCCGCAT
CCAGGGGCCATAGTTGCAATTGGTATTTATAAAGCGAATCTTGGGAAGGTACTAATGTATTCACTCATTATTACATTTTT
TGCAGCGATTATTGCAGGTCCTATATTTGCGAAATGGATTCACAAACGTGTAATTCCTGAAAATGAGCCAGAATTGATTC
GTGTAAATACAAAATCAACGAAATTACCAGGAATAGGAGTTTCATTTTTAGTTATATTGTTACCTGTTATGTTAATGGTT
TTAGCTGCAGCAGCTCCTTATGTGCCTCTTTCTAATACTTTGATGAAGATTATCACATTAATCGGTAGTCCTATCATTGC
ACTATTGATTGCATGTTTTGCGGCGTTCTATTTTCTTGGATTTCGTCAAGGTATCGATAAAAAAGCTATTAAGAAGATAA
CAGAAGATAGCTTATTACCAATCGGTTCAATTGTTGCGATTATTGGTGCCGGCGGGGGTTTTAAGCAAATTCTTATCGAT
AGTGGGGTAGGGAATGCTATTGCTCAAATGTCTGAACATTTAGCTCTATCTCCAATTGTATTAGCATTTATAGTAGCTGG
TTTAATTCGAATTGCGACAGGGTCAGCGACAGTCGCCTTAACAACAGCAGCGGGTATCGTTTCGCCAATCGTTGAAAATA
CAACAGGTGTGAACTTAGAATTACTCGTTATTGCAACAGGTGCAGGAGCATTAATGTTTTCACACGTAAACGATGCTGGT
TTTTGGATGGTAAAAGAATACCTAGGTTTAACAGTGAAAGAAACATTTAAAACATGGACAGTATTAGAAACGTTACTTTC
ATTTATTGCTTTTGGAGGCGTTTTACTACTCGATATGTTTGTTTAA

Upstream 100 bases:

>100_bases
GTATATCGATATATAAATTCTTACTCATGAAAGAACGATATAGGTTCTCTTAATTGTATAGTAATTTTGAAAGGGTTTAC
ATAAAGGGGTGGAACTGAGT

Downstream 100 bases:

>100_bases
GATAAAGATGTTTCTATTTAGATAATTGTGGCATACAACGTTATCAATAGATAAAAGGAATGTATTTTTATGGTGGGATA
CTGTAACAATTTTTTGTTAG

Product: gluconate permease

Products: gluconate [Cytoplasm]; L-idonate [Cytoplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MNMYLLMITLLSIVIVILGVSWWRWHAFISLTVASLFLAIMSGMPMDKIVSAYETGVGSVLGHLVGILVLGTILGKMMAE
SGAGMQVAEFFIKSFGIKNLPWAMLIAGFIIGIPVFFEVGILILLPLVISIHKTTKQNILLIALPAIAGLSVVHGLVPPH
PGAIVAIGIYKANLGKVLMYSLIITFFAAIIAGPIFAKWIHKRVIPENEPELIRVNTKSTKLPGIGVSFLVILLPVMLMV
LAAAAPYVPLSNTLMKIITLIGSPIIALLIACFAAFYFLGFRQGIDKKAIKKITEDSLLPIGSIVAIIGAGGGFKQILID
SGVGNAIAQMSEHLALSPIVLAFIVAGLIRIATGSATVALTTAAGIVSPIVENTTGVNLELLVIATGAGALMFSHVNDAG
FWMVKEYLGLTVKETFKTWTVLETLLSFIAFGGVLLLDMFV

Sequences:

>Translated_441_residues
MNMYLLMITLLSIVIVILGVSWWRWHAFISLTVASLFLAIMSGMPMDKIVSAYETGVGSVLGHLVGILVLGTILGKMMAE
SGAGMQVAEFFIKSFGIKNLPWAMLIAGFIIGIPVFFEVGILILLPLVISIHKTTKQNILLIALPAIAGLSVVHGLVPPH
PGAIVAIGIYKANLGKVLMYSLIITFFAAIIAGPIFAKWIHKRVIPENEPELIRVNTKSTKLPGIGVSFLVILLPVMLMV
LAAAAPYVPLSNTLMKIITLIGSPIIALLIACFAAFYFLGFRQGIDKKAIKKITEDSLLPIGSIVAIIGAGGGFKQILID
SGVGNAIAQMSEHLALSPIVLAFIVAGLIRIATGSATVALTTAAGIVSPIVENTTGVNLELLVIATGAGALMFSHVNDAG
FWMVKEYLGLTVKETFKTWTVLETLLSFIAFGGVLLLDMFV
>Mature_441_residues
MNMYLLMITLLSIVIVILGVSWWRWHAFISLTVASLFLAIMSGMPMDKIVSAYETGVGSVLGHLVGILVLGTILGKMMAE
SGAGMQVAEFFIKSFGIKNLPWAMLIAGFIIGIPVFFEVGILILLPLVISIHKTTKQNILLIALPAIAGLSVVHGLVPPH
PGAIVAIGIYKANLGKVLMYSLIITFFAAIIAGPIFAKWIHKRVIPENEPELIRVNTKSTKLPGIGVSFLVILLPVMLMV
LAAAAPYVPLSNTLMKIITLIGSPIIALLIACFAAFYFLGFRQGIDKKAIKKITEDSLLPIGSIVAIIGAGGGFKQILID
SGVGNAIAQMSEHLALSPIVLAFIVAGLIRIATGSATVALTTAAGIVSPIVENTTGVNLELLVIATGAGALMFSHVNDAG
FWMVKEYLGLTVKETFKTWTVLETLLSFIAFGGVLLLDMFV

Specific function: Transport Of Gluconate And L-Idonate. [C]

COG id: COG2610

COG function: function code GE; H+/gluconate symporter and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gntP permease family [H]

Homologues:

Organism=Escherichia coli, GI48994935, Length=440, Percent_Identity=39.3181818181818, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI1790716, Length=421, Percent_Identity=40.6175771971496, Blast_Score=299, Evalue=2e-82,
Organism=Escherichia coli, GI2367370, Length=414, Percent_Identity=37.6811594202899, Blast_Score=267, Evalue=9e-73,
Organism=Escherichia coli, GI1788707, Length=443, Percent_Identity=36.7945823927765, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI48994939, Length=433, Percent_Identity=36.9515011547344, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1790776, Length=425, Percent_Identity=35.0588235294118, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1789097, Length=444, Percent_Identity=34.009009009009, Blast_Score=221, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003474 [H]

Pfam domain/function: PF02447 GntP_permease [H]

EC number: NA

Molecular weight: Translated: 46900; Mature: 46900

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMYLLMITLLSIVIVILGVSWWRWHAFISLTVASLFLAIMSGMPMDKIVSAYETGVGSV
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGHLVGILVLGTILGKMMAESGAGMQVAEFFIKSFGIKNLPWAMLIAGFIIGIPVFFEVG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ILILLPLVISIHKTTKQNILLIALPAIAGLSVVHGLVPPHPGAIVAIGIYKANLGKVLMY
HHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHH
SLIITFFAAIIAGPIFAKWIHKRVIPENEPELIRVNTKSTKLPGIGVSFLVILLPVMLMV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
LAAAAPYVPLSNTLMKIITLIGSPIIALLIACFAAFYFLGFRQGIDKKAIKKITEDSLLP
HHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
IGSIVAIIGAGGGFKQILIDSGVGNAIAQMSEHLALSPIVLAFIVAGLIRIATGSATVAL
HHHHHHHHCCCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TTAAGIVSPIVENTTGVNLELLVIATGAGALMFSHVNDAGFWMVKEYLGLTVKETFKTWT
HHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
VLETLLSFIAFGGVLLLDMFV
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNMYLLMITLLSIVIVILGVSWWRWHAFISLTVASLFLAIMSGMPMDKIVSAYETGVGSV
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LGHLVGILVLGTILGKMMAESGAGMQVAEFFIKSFGIKNLPWAMLIAGFIIGIPVFFEVG
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHH
ILILLPLVISIHKTTKQNILLIALPAIAGLSVVHGLVPPHPGAIVAIGIYKANLGKVLMY
HHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHH
SLIITFFAAIIAGPIFAKWIHKRVIPENEPELIRVNTKSTKLPGIGVSFLVILLPVMLMV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHH
LAAAAPYVPLSNTLMKIITLIGSPIIALLIACFAAFYFLGFRQGIDKKAIKKITEDSLLP
HHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCC
IGSIVAIIGAGGGFKQILIDSGVGNAIAQMSEHLALSPIVLAFIVAGLIRIATGSATVAL
HHHHHHHHCCCCCHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
TTAAGIVSPIVENTTGVNLELLVIATGAGALMFSHVNDAGFWMVKEYLGLTVKETFKTWT
HHHHHHHHHHHCCCCCCCEEEEEEEECCCHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHH
VLETLLSFIAFGGVLLLDMFV
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: gluconate [Periplasm]; Proton [Periplasm]; L-idonate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + gluconate [Periplasm] = Proton [Cytoplasm] + gluconate [Cytoplasm] Proton [Periplasm] + L-idonate [Periplasm] = L-idonate [Cytoplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]