Click here to switch to the map view.

The map label for this gene is ygcA [C]

Identifier: 218233353

GI number: 218233353

Start: 356301

End: 357665

Strand: Direct

Name: ygcA [C]

Synonym: BCB4264_A0381

Alternate gene names: 218233353

Gene position: 356301-357665 (Clockwise)

Preceding gene: 218232725

Following gene: 218235838

Centisome position: 6.57

GC content: 40.88

Gene sequence:

>1365_bases
ATGACGCCACCAGTTGAGAAAAACGAGTTTATAGATGTAGTATTTGAAGATTTAACACATGATGGTGCCGGTGTTGCGAA
AGTAAAGGGCTATCCTATTTTCGTTAAAAACGGATTACCAGGTGAAGAAGCGCAAATTAAAATTATTAAAGTGAAGAAAA
ACTTCGCATTTGGTCGTTTAATGAAGCTTCATACAGAAAGTCCATATCGTAAAGATGCTGAATGCCCAGTATATAATCAG
TGCGGCGGTTGTCAGCTTCAGCACTTATCATATGAGGGACAATTACAGGCGAAAGAAAAGCAAGTACGTGACGTTATGCA
ACGCATTGGAGGACTAGCTGATGTTCCTGTTCATCCTGTACTTGGCATGCAAAATCCGTGGGTATACCGTAATAAAGCAC
AAGTACCAATCGGAGAACGTGAAGGCGGACTTGTAGCTGGTTTTTATCGCCAAGGAACGCATGACATCATTAATATGGAA
TCATGCTTAATTCAGGCAGAAGAAAACGATACATTAATCCAAGAAGTAAAACGTATTTGTGAAAAGCACGGTATCACTGC
GTACAACGAAGAGCGTAACAAAGGAACACTTCGTCACGTAATGGCTCGTTACGGACAAGTAACAGGGGAAATTATGCTTG
TCTTCATTACGCGTACAGCAGAATTGCCGAACAAAAAAGCAATCATTGAAGAAATTGCAGCGAAATTCCCAGAAGTAAAA
TCAATCGTTCAAAACGTAAATACGAAGCGTACAAACGTAATTTTCGGAGACAAAACGACAGTATTATACGGATCAGAATA
TATTTATGACTTTATCGGTGACATTAAATTTGCGATTTCAGCACGTTCATTCTATCAAGTAAACCCAGAGCAAACGAAAG
TGCTTTACGATAAAACGTTAGAATACGCAAAATTAAATGGTAACGAAACAGTAATCGATGCCTATTGCGGAATCGGATCA
ATCTCGTTATTCCTAGCGCAAAAAGCGAAAAAAGTGTACGGCGTTGAAATCGTCCCAGAAGCAATCGAAGACGCAAACCG
AAACGCAGCACTAAACAACATGACAAACGCTGAATTTGGCGTAGGAGAAGCAGAAGTAGTCATTCCAAAATGGTACAAAG
AAGGCGTAATCGCCGACACAATGGTCGTAGACCCACCGCGTAAAGGCTGTGACGAAGCATTACTAAACACAATCATCGAC
ATGAAGCCAAACCGCGTCGTATACGTATCATGTAACCCAGCAACATTAGCACGTGATTTAAAAGTACTAGAAGAAGGCGG
ATATAAAACGCAGGAAGTACAACCTGTCGATATGTTCCCGCATACGACTCATGTGGAGTGTGTGGCTTGGCTTAAGTTGG
TATAA

Upstream 100 bases:

>100_bases
CGTCAATAGCTTTTTTTCTTCCAATAGAAAAAGACCATATAAGTATGATAAAATGTAACGCAGTGTTATGAAAAAGAGAG
GTCGGAAAATGAGTACTAAA

Downstream 100 bases:

>100_bases
TAGGAAAGCAGTTGATATAGGAAAATCTATACCATCTGCTTTTTGGTTTACAAAAATACCATTCATAAGCGATTTTAGTT
AAAATAAATATTGCTGATTT

Product: RNA methyltransferase, TrmA family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MTPPVEKNEFIDVVFEDLTHDGAGVAKVKGYPIFVKNGLPGEEAQIKIIKVKKNFAFGRLMKLHTESPYRKDAECPVYNQ
CGGCQLQHLSYEGQLQAKEKQVRDVMQRIGGLADVPVHPVLGMQNPWVYRNKAQVPIGEREGGLVAGFYRQGTHDIINME
SCLIQAEENDTLIQEVKRICEKHGITAYNEERNKGTLRHVMARYGQVTGEIMLVFITRTAELPNKKAIIEEIAAKFPEVK
SIVQNVNTKRTNVIFGDKTTVLYGSEYIYDFIGDIKFAISARSFYQVNPEQTKVLYDKTLEYAKLNGNETVIDAYCGIGS
ISLFLAQKAKKVYGVEIVPEAIEDANRNAALNNMTNAEFGVGEAEVVIPKWYKEGVIADTMVVDPPRKGCDEALLNTIID
MKPNRVVYVSCNPATLARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV

Sequences:

>Translated_454_residues
MTPPVEKNEFIDVVFEDLTHDGAGVAKVKGYPIFVKNGLPGEEAQIKIIKVKKNFAFGRLMKLHTESPYRKDAECPVYNQ
CGGCQLQHLSYEGQLQAKEKQVRDVMQRIGGLADVPVHPVLGMQNPWVYRNKAQVPIGEREGGLVAGFYRQGTHDIINME
SCLIQAEENDTLIQEVKRICEKHGITAYNEERNKGTLRHVMARYGQVTGEIMLVFITRTAELPNKKAIIEEIAAKFPEVK
SIVQNVNTKRTNVIFGDKTTVLYGSEYIYDFIGDIKFAISARSFYQVNPEQTKVLYDKTLEYAKLNGNETVIDAYCGIGS
ISLFLAQKAKKVYGVEIVPEAIEDANRNAALNNMTNAEFGVGEAEVVIPKWYKEGVIADTMVVDPPRKGCDEALLNTIID
MKPNRVVYVSCNPATLARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV
>Mature_453_residues
TPPVEKNEFIDVVFEDLTHDGAGVAKVKGYPIFVKNGLPGEEAQIKIIKVKKNFAFGRLMKLHTESPYRKDAECPVYNQC
GGCQLQHLSYEGQLQAKEKQVRDVMQRIGGLADVPVHPVLGMQNPWVYRNKAQVPIGEREGGLVAGFYRQGTHDIINMES
CLIQAEENDTLIQEVKRICEKHGITAYNEERNKGTLRHVMARYGQVTGEIMLVFITRTAELPNKKAIIEEIAAKFPEVKS
IVQNVNTKRTNVIFGDKTTVLYGSEYIYDFIGDIKFAISARSFYQVNPEQTKVLYDKTLEYAKLNGNETVIDAYCGIGSI
SLFLAQKAKKVYGVEIVPEAIEDANRNAALNNMTNAEFGVGEAEVVIPKWYKEGVIADTMVVDPPRKGCDEALLNTIIDM
KPNRVVYVSCNPATLARDLKVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI34222389, Length=346, Percent_Identity=27.4566473988439, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI51173878, Length=346, Percent_Identity=27.4566473988439, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI269784680, Length=427, Percent_Identity=25.5269320843091, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI269784676, Length=427, Percent_Identity=25.5269320843091, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI20149688, Length=427, Percent_Identity=25.5269320843091, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI269784678, Length=205, Percent_Identity=33.1707317073171, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1789148, Length=455, Percent_Identity=30.5494505494506, Blast_Score=202, Evalue=5e-53,
Organism=Escherichia coli, GI1787083, Length=386, Percent_Identity=26.9430051813472, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790403, Length=181, Percent_Identity=29.8342541436464, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI71997438, Length=163, Percent_Identity=33.1288343558282, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322909, Length=430, Percent_Identity=25.5813953488372, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24666579, Length=410, Percent_Identity=30, Blast_Score=160, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR002792
- InterPro:   IPR010280
- InterPro:   IPR003402 [H]

Pfam domain/function: PF02475 Met_10; PF01938 TRAM; PF05958 tRNA_U5-meth_tr [H]

EC number: NA

Molecular weight: Translated: 50867; Mature: 50736

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50926 TRAM ; PS01230 TRMA_1 ; PS01231 TRMA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPPVEKNEFIDVVFEDLTHDGAGVAKVKGYPIFVKNGLPGEEAQIKIIKVKKNFAFGRL
CCCCCCCCHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCCCEEEEEEEECCCCHHHH
MKLHTESPYRKDAECPVYNQCGGCQLQHLSYEGQLQAKEKQVRDVMQRIGGLADVPVHPV
HEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
LGMQNPWVYRNKAQVPIGEREGGLVAGFYRQGTHDIINMESCLIQAEENDTLIQEVKRIC
CCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCHHEECHHHEEEECCCCHHHHHHHHHH
EKHGITAYNEERNKGTLRHVMARYGQVTGEIMLVFITRTAELPNKKAIIEEIAAKFPEVK
HHCCCEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCHHHH
SIVQNVNTKRTNVIFGDKTTVLYGSEYIYDFIGDIKFAISARSFYQVNPEQTKVLYDKTL
HHHHCCCCCCCEEEECCCEEEEECCHHHHHHHCCEEEEEEECEEEEECHHHHHHHHHHCH
EYAKLNGNETVIDAYCGIGSISLFLAQKAKKVYGVEIVPEAIEDANRNAALNNMTNAEFG
HEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCEEECCHHHHCCCCCCHHCCCCCCCCC
VGEAEVVIPKWYKEGVIADTMVVDPPRKGCDEALLNTIIDMKPNRVVYVSCNPATLARDL
CCCEEEEEECHHCCCCEECEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHH
KVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TPPVEKNEFIDVVFEDLTHDGAGVAKVKGYPIFVKNGLPGEEAQIKIIKVKKNFAFGRL
CCCCCCCHHHHHHHHHHCCCCCCEEEECCEEEEEECCCCCCCCEEEEEEEECCCCHHHH
MKLHTESPYRKDAECPVYNQCGGCQLQHLSYEGQLQAKEKQVRDVMQRIGGLADVPVHPV
HEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
LGMQNPWVYRNKAQVPIGEREGGLVAGFYRQGTHDIINMESCLIQAEENDTLIQEVKRIC
CCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCHHEECHHHEEEECCCCHHHHHHHHHH
EKHGITAYNEERNKGTLRHVMARYGQVTGEIMLVFITRTAELPNKKAIIEEIAAKFPEVK
HHCCCEEECCCCCCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCHHHH
SIVQNVNTKRTNVIFGDKTTVLYGSEYIYDFIGDIKFAISARSFYQVNPEQTKVLYDKTL
HHHHCCCCCCCEEEECCCEEEEECCHHHHHHHCCEEEEEEECEEEEECHHHHHHHHHHCH
EYAKLNGNETVIDAYCGIGSISLFLAQKAKKVYGVEIVPEAIEDANRNAALNNMTNAEFG
HEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCEEECCHHHHCCCCCCHHCCCCCCCCC
VGEAEVVIPKWYKEGVIADTMVVDPPRKGCDEALLNTIIDMKPNRVVYVSCNPATLARDL
CCCEEEEEECHHCCCCEECEEEECCCCCCHHHHHHHHHHCCCCCEEEEEECCHHHHHHHH
KVLEEGGYKTQEVQPVDMFPHTTHVECVAWLKLV
HHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA