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The map label for this gene is dppE [H]

Identifier: 218233091

GI number: 218233091

Start: 3613959

End: 3615662

Strand: Reverse

Name: dppE [H]

Synonym: BCB4264_A3696

Alternate gene names: 218233091

Gene position: 3615662-3613959 (Counterclockwise)

Preceding gene: 218232428

Following gene: 218231950

Centisome position: 66.72

GC content: 35.09

Gene sequence:

>1704_bases
ATGAAAAAGAAACAAATGAAAAAACTAACAGCAGTTGTAGCACCGGTTTTAGCAATGAGCATGGCGTTAACAGCATGTTC
TACATCAGGTGGAGATAAGAAGACAAGCACAAATTCTAGCTCTAGTGGAGATAGTAAATCAGGGGAAAAATTAGCAGCAA
AACAAGTGTTAAATCGTACAGAAACAAATGAGATCCCAACAATGGATACTTCAAAAAATACAGATACATTAGGTTCTCAA
ATTTTAGGGAACACAATGGAAGGGTTATATCGATTAGATAAAGATAATAAACCAATCCCAGCTGCAGCAGAATCTAGTAC
GAAAAGTGAAGATGGTAAAAAATATACATTTAAACTACGTAAAGATGCAAAATGGTCAAATGGTGATCCTGTAACAGCAA
AAGACTTTGCTTATGCATGGCAACGATTATTAGATCCAAAAACAACTGCAGAATATGCGTTTATCGCATTCCCAATTAAA
AATGCAGAGGCGATTAATAAAGGTGAAAAACCAGTAACTGAACTAGGAGTTAAGGCGGTAGATGACTATACATTAGAAGT
TGAATTAGAACAAGCGGTACCATACTTCTTAAACTTAGTAGCGTTCCCATCGTACTATCCATTAAATGAGAAGTTCGTAA
AAGAAAAAGGTGATAAATACGGTTTAGAGTCTGATACAACAGTATATAACGGACCATTCGTTCTTACTGATTGGAAGCAT
GAGCAAGGCTGGAAACTAAAGAAAAATGATCAATATTGGGATAAAAAGACTGTAAAATTAGATGAAATCAACTATAGTGT
AGTAAAAGAAATAAATACAAGGGTCAACTTATTTGATACAGGTGCAATTGATTTCGCACTTCTATCAGGTGAATTCGTTG
ACAAATATAGAAATAACAAAGAGGAGTTTGGCACATACTCACAAGTAAGTACATTCTTCTTACGTATGAATCAAAAACGT
GGTGGACAAGATACACCATTAAAGAGTCAGAAATTACGTGAAGCAATCGCGCTTTCTATCGATAAGAAAAACCTAGCAAA
CGTTATTTTAAATGACGGATCTAAACCAGCAGACTTCTTAGTACCGAAAGGGTTAGCGACTGGACCAGACGGAAAAGACT
TCCAAGAAACATTTAAAAATGGTATCAAACCAGATGCGAAAAAAGCTGCTGCAGCCTGGGAAGAAGCGAAAAAAGAACTT
GGCAAAGACCAAGTTACAATTGAGTTATTAAACTATGATACTGGTAATGCGAAAAAAGTAGGGGAATATGTAAAAGACCA
AATTGAGAAAAATTTAAAAGGTGTAACAGTTAATATTAAACTTCAGCCATTCAAACAAAAACTAAAACTAGAAACAGAGC
AAGATTATGATTTATCATATGCTGGTTGGGGACCTGACTATGCTGACCCAATGACATTCTTAGATATGTTCCAGTCTAAA
CATTCTCATAACCAAATGAGCTTCGCTGATCCAAAGTATGATGATATGATCAAAAAAGCTGGCACTGAATTAATGGGTGA
CGCGAAGAAACGTTGGGAAGAGCTAGGAAAAGCTGAGAAATTACTTCTTGAGAAAGATGTAGCACTTGTACCTTTATACC
AACGTGGTGATGCATATGTTCTAAAACAAAATATTAAAGGTATTGTAAAACATAATATCAGTCCGGAATATAGCTTTAAA
TGGGCATATGTAACTGAAAAATAA

Upstream 100 bases:

>100_bases
AATAAGAATTAGTAAGAATCGTCTGATAAATATATAGAGAAAAACAGAATTATCAGAAAATTCTTTAATAGCTATCGTTA
AGAATTAGGGAGGGTACAAA

Downstream 100 bases:

>100_bases
TAAAGTTAAAAAAGCATTTCAAAGTAGCTTAGCTACTTTGAAATGCTTTTTTTGTGAGCTTAAAATACTAATTTTTAGTA
TGGTTAAATAGAGGAGAATA

Product: putative oligopeptide ABC transporter, oligopeptide-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 567

Protein sequence:

>567_residues
MKKKQMKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSSGDSKSGEKLAAKQVLNRTETNEIPTMDTSKNTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFAYAWQRLLDPKTTAEYAFIAFPIK
NAEAINKGEKPVTELGVKAVDDYTLEVELEQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKH
EQGWKLKKNDQYWDKKTVKLDEINYSVVKEINTRVNLFDTGAIDFALLSGEFVDKYRNNKEEFGTYSQVSTFFLRMNQKR
GGQDTPLKSQKLREAIALSIDKKNLANVILNDGSKPADFLVPKGLATGPDGKDFQETFKNGIKPDAKKAAAAWEEAKKEL
GKDQVTIELLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQPFKQKLKLETEQDYDLSYAGWGPDYADPMTFLDMFQSK
HSHNQMSFADPKYDDMIKKAGTELMGDAKKRWEELGKAEKLLLEKDVALVPLYQRGDAYVLKQNIKGIVKHNISPEYSFK
WAYVTEK

Sequences:

>Translated_567_residues
MKKKQMKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSSGDSKSGEKLAAKQVLNRTETNEIPTMDTSKNTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFAYAWQRLLDPKTTAEYAFIAFPIK
NAEAINKGEKPVTELGVKAVDDYTLEVELEQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKH
EQGWKLKKNDQYWDKKTVKLDEINYSVVKEINTRVNLFDTGAIDFALLSGEFVDKYRNNKEEFGTYSQVSTFFLRMNQKR
GGQDTPLKSQKLREAIALSIDKKNLANVILNDGSKPADFLVPKGLATGPDGKDFQETFKNGIKPDAKKAAAAWEEAKKEL
GKDQVTIELLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQPFKQKLKLETEQDYDLSYAGWGPDYADPMTFLDMFQSK
HSHNQMSFADPKYDDMIKKAGTELMGDAKKRWEELGKAEKLLLEKDVALVPLYQRGDAYVLKQNIKGIVKHNISPEYSFK
WAYVTEK
>Mature_567_residues
MKKKQMKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSSGDSKSGEKLAAKQVLNRTETNEIPTMDTSKNTDTLGSQ
ILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLRKDAKWSNGDPVTAKDFAYAWQRLLDPKTTAEYAFIAFPIK
NAEAINKGEKPVTELGVKAVDDYTLEVELEQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKH
EQGWKLKKNDQYWDKKTVKLDEINYSVVKEINTRVNLFDTGAIDFALLSGEFVDKYRNNKEEFGTYSQVSTFFLRMNQKR
GGQDTPLKSQKLREAIALSIDKKNLANVILNDGSKPADFLVPKGLATGPDGKDFQETFKNGIKPDAKKAAAAWEEAKKEL
GKDQVTIELLNYDTGNAKKVGEYVKDQIEKNLKGVTVNIKLQPFKQKLKLETEQDYDLSYAGWGPDYADPMTFLDMFQSK
HSHNQMSFADPKYDDMIKKAGTELMGDAKKRWEELGKAEKLLLEKDVALVPLYQRGDAYVLKQNIKGIVKHNISPEYSFK
WAYVTEK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=550, Percent_Identity=31.4545454545455, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI87081878, Length=540, Percent_Identity=29.2592592592593, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1789397, Length=518, Percent_Identity=28.7644787644788, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1787762, Length=457, Percent_Identity=24.72647702407, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1787052, Length=318, Percent_Identity=28.3018867924528, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1789887, Length=341, Percent_Identity=27.2727272727273, Blast_Score=89, Evalue=9e-19,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 63780; Mature: 63780

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKQMKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSSGDSKSGEKLAAKQVLNRT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
ETNEIPTMDTSKNTDTLGSQILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
KDAKWSNGDPVTAKDFAYAWQRLLDPKTTAEYAFIAFPIKNAEAINKGEKPVTELGVKAV
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHCCCCCCHHHHCCCCC
DDYTLEVELEQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKH
CCEEEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEECCCC
EQGWKLKKNDQYWDKKTVKLDEINYSVVKEINTRVNLFDTGAIDFALLSGEFVDKYRNNK
CCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCEEEEEECCCEEEEECCCHHHHHHCCCH
EEFGTYSQVSTFFLRMNQKRGGQDTPLKSQKLREAIALSIDKKNLANVILNDGSKPADFL
HHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHEECCCCCCCHHC
VPKGLATGPDGKDFQETFKNGIKPDAKKAAAAWEEAKKELGKDQVTIELLNYDTGNAKKV
CCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHH
GEYVKDQIEKNLKGVTVNIKLQPFKQKLKLETEQDYDLSYAGWGPDYADPMTFLDMFQSK
HHHHHHHHHCCCCEEEEEEEECCHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHH
HSHNQMSFADPKYDDMIKKAGTELMGDAKKRWEELGKAEKLLLEKDVALVPLYQRGDAYV
CCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEE
LKQNIKGIVKHNISPEYSFKWAYVTEK
EHHHHHHHHHCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MKKKQMKKLTAVVAPVLAMSMALTACSTSGGDKKTSTNSSSSGDSKSGEKLAAKQVLNRT
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
ETNEIPTMDTSKNTDTLGSQILGNTMEGLYRLDKDNKPIPAAAESSTKSEDGKKYTFKLR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
KDAKWSNGDPVTAKDFAYAWQRLLDPKTTAEYAFIAFPIKNAEAINKGEKPVTELGVKAV
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHCCCCCCHHHHCCCCC
DDYTLEVELEQAVPYFLNLVAFPSYYPLNEKFVKEKGDKYGLESDTTVYNGPFVLTDWKH
CCEEEEEEHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCCEEECCCEEEECCCC
EQGWKLKKNDQYWDKKTVKLDEINYSVVKEINTRVNLFDTGAIDFALLSGEFVDKYRNNK
CCCCCCCCCCCCCCCCCEEEECCCHHHHHHHCCEEEEEECCCEEEEECCCHHHHHHCCCH
EEFGTYSQVSTFFLRMNQKRGGQDTPLKSQKLREAIALSIDKKNLANVILNDGSKPADFL
HHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHEECCCCCCCHHC
VPKGLATGPDGKDFQETFKNGIKPDAKKAAAAWEEAKKELGKDQVTIELLNYDTGNAKKV
CCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHH
GEYVKDQIEKNLKGVTVNIKLQPFKQKLKLETEQDYDLSYAGWGPDYADPMTFLDMFQSK
HHHHHHHHHCCCCEEEEEEEECCHHHHHCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHH
HSHNQMSFADPKYDDMIKKAGTELMGDAKKRWEELGKAEKLLLEKDVALVPLYQRGDAYV
CCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEE
LKQNIKGIVKHNISPEYSFKWAYVTEK
EHHHHHHHHHCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]