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The map label for this gene is dppE [H]

Identifier: 218232913

GI number: 218232913

Start: 186635

End: 188245

Strand: Direct

Name: dppE [H]

Synonym: BCB4264_A0214

Alternate gene names: 218232913

Gene position: 186635-188245 (Clockwise)

Preceding gene: 218231314

Following gene: 218235537

Centisome position: 3.44

GC content: 33.33

Gene sequence:

>1611_bases
ATGAAGAAGTTTTTACTGTTTGTCATTATGACTGTTTTAGCGATTACTTCTGTCGCTTGCGGTAAGAAAGAGACGCAAAA
GGCGAGTGCTGGTAAGGGAGAAGGAGATCGATTAGTAACGAATATTAGTAGTGATCCATATACACTTGATTCTGCTATTG
CAACAGATAGCACGTCAGGTTATATAATTGGGCAGTTGTTTTCAAGTTTATATACGCAAGATAGTAATGGGAAATATCAA
AATGAATTAGCGGAGAAAGAAGAAGTAAATGCTGATGGAACTGAATATACAATCCATTTGAAGAAAGATATTAAATGGTC
AGATGGTTCTCCTATTACAGCAAATGATTTTGAATTTGCATGGAAGCGATTATTAAATCCGAAAACGGGTTCTATGAATG
CGACAGAAATGTATTTTATTAAAGGGGCAGAGGCGTATAATACTGGAAAAGGTGAAGAGGGACAAGTTGGTATTCAAGTT
GTTGATCCTCAAACATTAAAGGTAACCCTTGAACACCCAGTTGCTTCTATTAAACAAAAACTAGCAAGCTCACTATTTAT
TCCATTAGCTAAAAAGTCGATTGATGATAATAATAAATTAAAAACAGATCCAAAAGAGTTAATTACGAATGGGCCATTCA
CGTTAAAAGAGTGGAAGCATAACCAAGCTATTACAGTACAAAAAAATAAAGAATTCTATGATAAAAAGGTAACTCTAAAA
GAAATTGAGTTTCGTATTATTCCAGACTCTAAAACAGCGTATCAATTATTTAAATCCAAAGAATTAGATTTACTAAGTGG
TTTACCACAAGAGATGATCGAAAAAGAAAAAGGAAATAAAGAATATAAGCGTGTTGCAGGGTTCTCTTCTTATATTTATT
CGTTTAACGTAGAAAAAGAGCCGTTTACAAATGCGAAGGTACGTAAAGCATTTTCATTAGCGGTTGATCGTAAATTTATC
GTTGAAAAATTGTATAAAAATAATGCGCAAGAAGCATATGCATTCGTTCCAGAAGGAGCAAAAACACAAAGTGGCCGTGA
TTTCCGTAAAGAAAAAGGTGATTACGTTAAATTTGATCCAGCGGAAGCGAAAAAGTTATTAGAAGAAGGCATGAAAGAAC
AAGGCTGGTCTACATTACCTGAAGTAACATTAAAATTCACTACAGATACACAACATAAAAAAGTAGCAGAAGCAATGCAA
GAAATGTTTAAGAAAAATCTTGGCGTAGATATTAAATTAGAAAATAAAGAGTGGAAGAGTTACATCGACACATACAAGCA
AAGTGATTTCCAATTAGCTTATATGGGATGGGGCGGCTCTTTATTAGATCCAATTACTAAACTAGATTTATATGCGGGTG
ATGGTCCAAATAACTATGCAAAATGGCATAATAAAGAATTTGACGCTTTAATAAAAGAAGCAAAAGTTGAACAAAACGAG
GATAAGCGTTTTGAATTATTGCATAAAGCGGAAGATATTATGTTTACAGATTCACCATTAATCCCAATTATTTTCCCAAG
TGCTTCCTATTTACAAAAATCATCAGTATCCGGTGTCCAATTCATTATTGGTTCTAGTCCAGAATTAAGATACGCAAAAA
TTAAAAAATAA

Upstream 100 bases:

>100_bases
TTTGGAAATACGGACGAAGTATTCCGTAATCCACAACATTCTTATACAAAAACATTATTAGCATCAACACCAAAAATTTC
AGGTTAAAGGAGAATGTAGG

Downstream 100 bases:

>100_bases
AGAAGTAGGCAACGGCCTACTTCTTTATTTTATTTCTCTTTTATATTCTTTTTTCGTTCCATCAGAGAAGACAACTTCTA
AATCGAATTTTTGATAGTCT

Product: oligopeptide ABC transporter, oligopeptide-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 536

Protein sequence:

>536_residues
MKKFLLFVIMTVLAITSVACGKKETQKASAGKGEGDRLVTNISSDPYTLDSAIATDSTSGYIIGQLFSSLYTQDSNGKYQ
NELAEKEEVNADGTEYTIHLKKDIKWSDGSPITANDFEFAWKRLLNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQV
VDPQTLKVTLEHPVASIKQKLASSLFIPLAKKSIDDNNKLKTDPKELITNGPFTLKEWKHNQAITVQKNKEFYDKKVTLK
EIEFRIIPDSKTAYQLFKSKELDLLSGLPQEMIEKEKGNKEYKRVAGFSSYIYSFNVEKEPFTNAKVRKAFSLAVDRKFI
VEKLYKNNAQEAYAFVPEGAKTQSGRDFRKEKGDYVKFDPAEAKKLLEEGMKEQGWSTLPEVTLKFTTDTQHKKVAEAMQ
EMFKKNLGVDIKLENKEWKSYIDTYKQSDFQLAYMGWGGSLLDPITKLDLYAGDGPNNYAKWHNKEFDALIKEAKVEQNE
DKRFELLHKAEDIMFTDSPLIPIIFPSASYLQKSSVSGVQFIIGSSPELRYAKIKK

Sequences:

>Translated_536_residues
MKKFLLFVIMTVLAITSVACGKKETQKASAGKGEGDRLVTNISSDPYTLDSAIATDSTSGYIIGQLFSSLYTQDSNGKYQ
NELAEKEEVNADGTEYTIHLKKDIKWSDGSPITANDFEFAWKRLLNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQV
VDPQTLKVTLEHPVASIKQKLASSLFIPLAKKSIDDNNKLKTDPKELITNGPFTLKEWKHNQAITVQKNKEFYDKKVTLK
EIEFRIIPDSKTAYQLFKSKELDLLSGLPQEMIEKEKGNKEYKRVAGFSSYIYSFNVEKEPFTNAKVRKAFSLAVDRKFI
VEKLYKNNAQEAYAFVPEGAKTQSGRDFRKEKGDYVKFDPAEAKKLLEEGMKEQGWSTLPEVTLKFTTDTQHKKVAEAMQ
EMFKKNLGVDIKLENKEWKSYIDTYKQSDFQLAYMGWGGSLLDPITKLDLYAGDGPNNYAKWHNKEFDALIKEAKVEQNE
DKRFELLHKAEDIMFTDSPLIPIIFPSASYLQKSSVSGVQFIIGSSPELRYAKIKK
>Mature_536_residues
MKKFLLFVIMTVLAITSVACGKKETQKASAGKGEGDRLVTNISSDPYTLDSAIATDSTSGYIIGQLFSSLYTQDSNGKYQ
NELAEKEEVNADGTEYTIHLKKDIKWSDGSPITANDFEFAWKRLLNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQV
VDPQTLKVTLEHPVASIKQKLASSLFIPLAKKSIDDNNKLKTDPKELITNGPFTLKEWKHNQAITVQKNKEFYDKKVTLK
EIEFRIIPDSKTAYQLFKSKELDLLSGLPQEMIEKEKGNKEYKRVAGFSSYIYSFNVEKEPFTNAKVRKAFSLAVDRKFI
VEKLYKNNAQEAYAFVPEGAKTQSGRDFRKEKGDYVKFDPAEAKKLLEEGMKEQGWSTLPEVTLKFTTDTQHKKVAEAMQ
EMFKKNLGVDIKLENKEWKSYIDTYKQSDFQLAYMGWGGSLLDPITKLDLYAGDGPNNYAKWHNKEFDALIKEAKVEQNE
DKRFELLHKAEDIMFTDSPLIPIIFPSASYLQKSSVSGVQFIIGSSPELRYAKIKK

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789397, Length=484, Percent_Identity=31.8181818181818, Blast_Score=237, Evalue=2e-63,
Organism=Escherichia coli, GI87081878, Length=508, Percent_Identity=29.7244094488189, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI1787495, Length=504, Percent_Identity=30.952380952381, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1789966, Length=439, Percent_Identity=28.246013667426, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1787052, Length=505, Percent_Identity=25.1485148514851, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787762, Length=493, Percent_Identity=23.7322515212982, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787551, Length=476, Percent_Identity=21.218487394958, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789887, Length=411, Percent_Identity=24.330900243309, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60711; Mature: 60711

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS01040 SBP_BACTERIAL_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFLLFVIMTVLAITSVACGKKETQKASAGKGEGDRLVTNISSDPYTLDSAIATDSTSG
CHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEEEEECCCCCEECCHHHCCCCCCC
YIIGQLFSSLYTQDSNGKYQNELAEKEEVNADGTEYTIHLKKDIKWSDGSPITANDFEFA
EEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHH
WKRLLNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQVVDPQTLKVTLEHPVASIKQK
HHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEECCHHHHHHHH
LASSLFIPLAKKSIDDNNKLKTDPKELITNGPFTLKEWKHNQAITVQKNKEFYDKKVTLK
HHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEHHCCCCCEEEEECCCHHHHHCCEEE
EIEFRIIPDSKTAYQLFKSKELDLLSGLPQEMIEKEKGNKEYKRVAGFSSYIYSFNVEKE
EEEEEEECCCHHHHHHHHCCCCHHHHCCCHHHHHHHCCCHHHHHHHHHHHEEEEECCCCC
PFTNAKVRKAFSLAVDRKFIVEKLYKNNAQEAYAFVPEGAKTQSGRDFRKEKGDYVKFDP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHCCCCEEEECH
AEAKKLLEEGMKEQGWSTLPEVTLKFTTDTQHKKVAEAMQEMFKKNLGVDIKLENKEWKS
HHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHH
YIDTYKQSDFQLAYMGWGGSLLDPITKLDLYAGDGPNNYAKWHNKEFDALIKEAKVEQNE
HHHHHCCCCCEEEEEECCCHHHHHHHHHEEEECCCCCCCHHCCCCHHHHHHHHHHCCCCC
DKRFELLHKAEDIMFTDSPLIPIIFPSASYLQKSSVSGVQFIIGSSPELRYAKIKK
CHHHHHHHHHHHEEEECCCCCEEEECCHHHHHHCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MKKFLLFVIMTVLAITSVACGKKETQKASAGKGEGDRLVTNISSDPYTLDSAIATDSTSG
CHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCEEEEECCCCCEECCHHHCCCCCCC
YIIGQLFSSLYTQDSNGKYQNELAEKEEVNADGTEYTIHLKKDIKWSDGSPITANDFEFA
EEHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCHHHHH
WKRLLNPKTGSMNATEMYFIKGAEAYNTGKGEEGQVGIQVVDPQTLKVTLEHPVASIKQK
HHHHCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECCCEEEEEECCHHHHHHHH
LASSLFIPLAKKSIDDNNKLKTDPKELITNGPFTLKEWKHNQAITVQKNKEFYDKKVTLK
HHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCEEHHCCCCCEEEEECCCHHHHHCCEEE
EIEFRIIPDSKTAYQLFKSKELDLLSGLPQEMIEKEKGNKEYKRVAGFSSYIYSFNVEKE
EEEEEEECCCHHHHHHHHCCCCHHHHCCCHHHHHHHCCCHHHHHHHHHHHEEEEECCCCC
PFTNAKVRKAFSLAVDRKFIVEKLYKNNAQEAYAFVPEGAKTQSGRDFRKEKGDYVKFDP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCHHHHCCCCEEEECH
AEAKKLLEEGMKEQGWSTLPEVTLKFTTDTQHKKVAEAMQEMFKKNLGVDIKLENKEWKS
HHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCCEEEEECCHHHHH
YIDTYKQSDFQLAYMGWGGSLLDPITKLDLYAGDGPNNYAKWHNKEFDALIKEAKVEQNE
HHHHHCCCCCEEEEEECCCHHHHHHHHHEEEECCCCCCCHHCCCCHHHHHHHHHHCCCCC
DKRFELLHKAEDIMFTDSPLIPIIFPSASYLQKSSVSGVQFIIGSSPELRYAKIKK
CHHHHHHHHHHHEEEECCCCCEEEECCHHHHHHCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]