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The map label for this gene is trpS [H]

Identifier: 218232880

GI number: 218232880

Start: 3230471

End: 3231469

Strand: Reverse

Name: trpS [H]

Synonym: BCB4264_A3353

Alternate gene names: 218232880

Gene position: 3231469-3230471 (Counterclockwise)

Preceding gene: 218234805

Following gene: 218235672

Centisome position: 59.63

GC content: 37.64

Gene sequence:

>999_bases
GTGAGTGAAAAAATAATGTTAACAGGAATTAAGCCGACAGGTTATCCACATTTAGGAAATTATATTGGTGCGATTAAACC
TGCATTACAAATGTCAAAGAATAATGAAGGAAAAGCATTGTACTTTATAGCTGATTATCATGCATTAAATGCTGTTCATG
ATTCAGAAAAGTTCAGCAGTTATACGAAAGAGGTAGCAGCTACTTGGTTATCGCTTGGATTTGGGGAAGATGTTGTTTTT
TATCGGCAAACAGAAGTACCGGAAATTCTAGAATTATCTTGGATTTTAGCTTGCCTAACTCCGAAAGGTCTTATGAACCG
TGCTCATGCGTATAAAGCGAAGGTGGAGCAAAATAAAGAAGCAGGGTTAGAGGTCGATGCGGGAGTGAACATGGGGGTAT
ATACGTACCCGATCTTAATGGCAGCTGACATATTACTATTTCAAGCTACACATGTACCTGTCGGAAAAGACCAAATTCAA
CATATTGAAATTGCGCGTGATATTGCGACGTATTTTAATCATACATTTGGCACGACATTTACACTACCGGAGTATGTCAT
ACAAGAAGAAGGAGCTATTTTACCTGGTCTTGATGGAAGGAAGATGAGTAAAAGTTACGGAAATGTAATCCCATTATTTG
CAGAGCAAGAAAAACTTCGAAAGTTAATATTTAAAATCAAAACAGACTCTTCACTTCCAAATGAACCGAAAGAACTAGAA
ACCTTATTTACAATTTATAAAGAATTTGCGACAGAAGACGAAGTACAGTCATTACGTGAAAAATATGAGACTGGAATCGG
ATGGGGCGATGTGAAAAAAGAGTTGTTTCGCGTTGTAGATCGTGAGTTAGCTGGACCTCGTGAAAAGTACGCAATGTATA
TGAATGAGCCGGATTTATTATATGAAGCATTAGAAAACGGTGCTGAGAAGGCACGCGCTATTGCAAAGGTAAATTTAGCG
GAAATTAAAAAACGGATTGGATTTGAGAGGGAACGTTAA

Upstream 100 bases:

>100_bases
GAAGTGAGCTAATGATAGCTAATTAAGGTGGTACCGCGGGAGTCTCTCGTCCTTTTTTAGGATGAGGGGCTCTTTTTATT
TTGAGAAAGGAGGAGTTAGT

Downstream 100 bases:

>100_bases
GCGTTCCCTTATTTTTTTAGATAATCTGTAATAATCTTCTCGATAACAGGAGGAAGATTATTAGGTAATTCATTAAGTGA
AAAGAAGCGTAGTTCTTTCG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSEKIMLTGIKPTGYPHLGNYIGAIKPALQMSKNNEGKALYFIADYHALNAVHDSEKFSSYTKEVAATWLSLGFGEDVVF
YRQTEVPEILELSWILACLTPKGLMNRAHAYKAKVEQNKEAGLEVDAGVNMGVYTYPILMAADILLFQATHVPVGKDQIQ
HIEIARDIATYFNHTFGTTFTLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELE
TLFTIYKEFATEDEVQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPDLLYEALENGAEKARAIAKVNLA
EIKKRIGFERER

Sequences:

>Translated_332_residues
MSEKIMLTGIKPTGYPHLGNYIGAIKPALQMSKNNEGKALYFIADYHALNAVHDSEKFSSYTKEVAATWLSLGFGEDVVF
YRQTEVPEILELSWILACLTPKGLMNRAHAYKAKVEQNKEAGLEVDAGVNMGVYTYPILMAADILLFQATHVPVGKDQIQ
HIEIARDIATYFNHTFGTTFTLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELE
TLFTIYKEFATEDEVQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPDLLYEALENGAEKARAIAKVNLA
EIKKRIGFERER
>Mature_331_residues
SEKIMLTGIKPTGYPHLGNYIGAIKPALQMSKNNEGKALYFIADYHALNAVHDSEKFSSYTKEVAATWLSLGFGEDVVFY
RQTEVPEILELSWILACLTPKGLMNRAHAYKAKVEQNKEAGLEVDAGVNMGVYTYPILMAADILLFQATHVPVGKDQIQH
IEIARDIATYFNHTFGTTFTLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELET
LFTIYKEFATEDEVQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPDLLYEALENGAEKARAIAKVNLAE
IKKRIGFERER

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=342, Percent_Identity=30.9941520467836, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI41352700, Length=187, Percent_Identity=37.4331550802139, Blast_Score=142, Evalue=6e-34,
Organism=Escherichia coli, GI1789786, Length=341, Percent_Identity=33.4310850439883, Blast_Score=169, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI71982800, Length=338, Percent_Identity=31.9526627218935, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI71982793, Length=338, Percent_Identity=31.9526627218935, Blast_Score=146, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320474, Length=349, Percent_Identity=34.3839541547278, Blast_Score=165, Evalue=8e-42,
Organism=Drosophila melanogaster, GI24666151, Length=335, Percent_Identity=30.4477611940298, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37604; Mature: 37472

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50237 HECT ; PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKIMLTGIKPTGYPHLGNYIGAIKPALQMSKNNEGKALYFIADYHALNAVHDSEKFSS
CCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHH
YTKEVAATWLSLGFGEDVVFYRQTEVPEILELSWILACLTPKGLMNRAHAYKAKVEQNKE
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHH
AGLEVDAGVNMGVYTYPILMAADILLFQATHVPVGKDQIQHIEIARDIATYFNHTFGTTF
CCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
TLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELE
CCHHHHHHCCCCCCCCCCCCHHHHHHCCEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
TLFTIYKEFATEDEVQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPDLL
HHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHEEECCCHHHH
YEALENGAEKARAIAKVNLAEIKKRIGFERER
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
SEKIMLTGIKPTGYPHLGNYIGAIKPALQMSKNNEGKALYFIADYHALNAVHDSEKFSS
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHHH
YTKEVAATWLSLGFGEDVVFYRQTEVPEILELSWILACLTPKGLMNRAHAYKAKVEQNKE
HHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHH
AGLEVDAGVNMGVYTYPILMAADILLFQATHVPVGKDQIQHIEIARDIATYFNHTFGTTF
CCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEE
TLPEYVIQEEGAILPGLDGRKMSKSYGNVIPLFAEQEKLRKLIFKIKTDSSLPNEPKELE
CCHHHHHHCCCCCCCCCCCCHHHHHHCCEECCCCCHHHHHHHHHHHCCCCCCCCCHHHHH
TLFTIYKEFATEDEVQSLREKYETGIGWGDVKKELFRVVDRELAGPREKYAMYMNEPDLL
HHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHEEECCCHHHH
YEALENGAEKARAIAKVNLAEIKKRIGFERER
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]