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The map label for this gene is schC [H]

Identifier: 218232643

GI number: 218232643

Start: 3384916

End: 3386535

Strand: Reverse

Name: schC [H]

Synonym: BCB4264_A3504

Alternate gene names: 218232643

Gene position: 3386535-3384916 (Counterclockwise)

Preceding gene: 218231910

Following gene: 218233413

Centisome position: 62.49

GC content: 37.41

Gene sequence:

>1620_bases
ATGAAATCGAATTATGTACCAGTTTTAATTGTTGGAGGGGGATTATCTGGGTTAGCGTCTGCGTTATTTCTTGCAAAACA
TAACATTGAGTACTTACTTATTGAAAGGCATCCGTCTACTGCCATTCATCCGAAAGCAGGCGGTCTCACTTTACGTACAA
TGGAGTTATTTCGAGAATTAGGCTTGAAAAAAAGAATTAAATTGGCAGGTAAAGCATTAGAGAACTGCCGAGGAAGAATA
GCGGTTCATACAATAGCTGAGGCGAATAAAGAAGAATTGGAACAAATGAGAGCGACACAATACGGAAACGATGAAGAGTT
ACTTCAAAAAATAGAAAAGATTAGTCCATCAAAACAAACTGCATGTTATCAAATTATTTTAGAAGAGATGATGTTACAAG
AAGCGAAAACATTAGGCGGGCAACTATCTTTTTATCATGAATTAGTTTCATTTGAACAAAATGAAAACGGGGTAAAAGCA
AAGATTCGAAATCGTGAAACAGAAAAAGAAAGTGTCATACATTGTGACTATGTAATTGCAGCAGATGGAGCGAAAAGTAA
AATACGTGAGCAGTTAGGGATTAAAACTGAGGGGCGTGGAACCATTGGTGGCTATTATATGAATATTTATTTTGAAGCAG
ACTTAAGTGAGTTTATACAAGGAGACGCATTCGGTTTTTCTATGGTACTTCATCCAGAGGTTCTTGGTGCACTGATCCCA
GTAGATAACGTAAAAAAATGGATTTACCATGTAGCCTACGATCCATTAAAAGGAGAGGGACCAGAGGATTTCACGATGGA
ACGTTGTAAACAAATTATTGAAATAGCAATTGGAAGTACAAATGTTGAGTCAGAAATATTAAGTGTTTTACCGTGGGAAG
CGGCCGAAAGTACAGCAATGAAATTTCAAGGAAATCGAGTCTTTCTAGTTGGAGATTCAGCACATATTATGCCGCCAACA
GGCGGATTTGGTTCAAATACAGGAATACAAGATGCGCATAACTTAGCTTGGAAATTAGCGGCTGTTATAAAAGGGAAGGC
AAAACCAAAATTGTTAGAAACATATCATGAAGAGAGACACTCTGTTGCAAAATTAACGACAGCTTATGCAAGTAGTTTAC
TGTTTCGTGCTGCGAATAGAGAGGAAGGCAGTTTGAATAATATGGATGGTTTAGCTGTTACAGTTGGATATCAGTATTGT
TCAGAGGCAATTATAGATGATTCAGTCACTCCGCATAGAATGGATAGCATAGAGTTGAACGGAAGACCTGGAACGCGCGC
GCCACATTTATGGGGAACGTATGAAGGGAAGAAAGTTTCTACATTAGACTTATTCGGTAACAGTTTTGTATTACTTACAG
GAGTAGAAAATAGTTCTTGGGCTGAGGCAGCACATGCTGTTTCAGCTAAATTAGGAATAAATATAAAAGGGTATCGTGTT
GGCTTAAGTGGAGACTTTGTTGTTCCAGAAGATATTTTTAGCAAATTATATGGTATAGAGAATGGAGGTGCTGTATTAAT
TAGACCAGATGGCTTTATCGGATGGCGTTCGGAAAAAACGGTAGTAAATCCAGATATAGTATTGGAAGAGGTAATGAGAA
ATTTATTATGTGATTTTTAA

Upstream 100 bases:

>100_bases
TATATGATAATTCAAAATGAAATATAAGTCTATATTTTAATGTTTTTTTTGATTATATTTATGTCACTGAGCTCAGAACA
ATGATTTGGAGGGGAAATAT

Downstream 100 bases:

>100_bases
GTAACTACAGAAATATTGTTTTATGTGCTTCACTCTACTGAAAAAAATATTCACAAATTTCAATAGGTTTGATATGATTA
AATTCGACAAGTTAATAGAG

Product: FAD-binding monooxygenase, PheA/TfdB family

Products: H2O; 3-(2,3-dihydroxyphenyl)propionate; NAD [C]

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 539

Protein sequence:

>539_residues
MKSNYVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGLTLRTMELFRELGLKKRIKLAGKALENCRGRI
AVHTIAEANKEELEQMRATQYGNDEELLQKIEKISPSKQTACYQIILEEMMLQEAKTLGGQLSFYHELVSFEQNENGVKA
KIRNRETEKESVIHCDYVIAADGAKSKIREQLGIKTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFSMVLHPEVLGALIP
VDNVKKWIYHVAYDPLKGEGPEDFTMERCKQIIEIAIGSTNVESEILSVLPWEAAESTAMKFQGNRVFLVGDSAHIMPPT
GGFGSNTGIQDAHNLAWKLAAVIKGKAKPKLLETYHEERHSVAKLTTAYASSLLFRAANREEGSLNNMDGLAVTVGYQYC
SEAIIDDSVTPHRMDSIELNGRPGTRAPHLWGTYEGKKVSTLDLFGNSFVLLTGVENSSWAEAAHAVSAKLGINIKGYRV
GLSGDFVVPEDIFSKLYGIENGGAVLIRPDGFIGWRSEKTVVNPDIVLEEVMRNLLCDF

Sequences:

>Translated_539_residues
MKSNYVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGLTLRTMELFRELGLKKRIKLAGKALENCRGRI
AVHTIAEANKEELEQMRATQYGNDEELLQKIEKISPSKQTACYQIILEEMMLQEAKTLGGQLSFYHELVSFEQNENGVKA
KIRNRETEKESVIHCDYVIAADGAKSKIREQLGIKTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFSMVLHPEVLGALIP
VDNVKKWIYHVAYDPLKGEGPEDFTMERCKQIIEIAIGSTNVESEILSVLPWEAAESTAMKFQGNRVFLVGDSAHIMPPT
GGFGSNTGIQDAHNLAWKLAAVIKGKAKPKLLETYHEERHSVAKLTTAYASSLLFRAANREEGSLNNMDGLAVTVGYQYC
SEAIIDDSVTPHRMDSIELNGRPGTRAPHLWGTYEGKKVSTLDLFGNSFVLLTGVENSSWAEAAHAVSAKLGINIKGYRV
GLSGDFVVPEDIFSKLYGIENGGAVLIRPDGFIGWRSEKTVVNPDIVLEEVMRNLLCDF
>Mature_539_residues
MKSNYVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGLTLRTMELFRELGLKKRIKLAGKALENCRGRI
AVHTIAEANKEELEQMRATQYGNDEELLQKIEKISPSKQTACYQIILEEMMLQEAKTLGGQLSFYHELVSFEQNENGVKA
KIRNRETEKESVIHCDYVIAADGAKSKIREQLGIKTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFSMVLHPEVLGALIP
VDNVKKWIYHVAYDPLKGEGPEDFTMERCKQIIEIAIGSTNVESEILSVLPWEAAESTAMKFQGNRVFLVGDSAHIMPPT
GGFGSNTGIQDAHNLAWKLAAVIKGKAKPKLLETYHEERHSVAKLTTAYASSLLFRAANREEGSLNNMDGLAVTVGYQYC
SEAIIDDSVTPHRMDSIELNGRPGTRAPHLWGTYEGKKVSTLDLFGNSFVLLTGVENSSWAEAAHAVSAKLGINIKGYRV
GLSGDFVVPEDIFSKLYGIENGGAVLIRPDGFIGWRSEKTVVNPDIVLEEVMRNLLCDF

Specific function: Involved in developmentally regulated synthesis of a compound biosynthetically related to polyketide antibiotics which is essential for spore color in Streptomyces halstedii [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=403, Percent_Identity=24.8138957816377, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.- [C]

Molecular weight: Translated: 59472; Mature: 59472

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNYVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGLTLRTMELFREL
CCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEHHHHHHHHHC
GLKKRIKLAGKALENCRGRIAVHTIAEANKEELEQMRATQYGNDEELLQKIEKISPSKQT
CHHHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
ACYQIILEEMMLQEAKTLGGQLSFYHELVSFEQNENGVKAKIRNRETEKESVIHCDYVIA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCHHCEEEEEEEEE
ADGAKSKIREQLGIKTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFSMVLHPEVLGALIP
CCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHCCCCCCEEEEECHHHHHHHCC
VDNVKKWIYHVAYDPLKGEGPEDFTMERCKQIIEIAIGSTNVESEILSVLPWEAAESTAM
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCE
KFQGNRVFLVGDSAHIMPPTGGFGSNTGIQDAHNLAWKLAAVIKGKAKPKLLETYHEERH
EECCCEEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SVAKLTTAYASSLLFRAANREEGSLNNMDGLAVTVGYQYCSEAIIDDSVTPHRMDSIELN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCCEEEEC
GRPGTRAPHLWGTYEGKKVSTLDLFGNSFVLLTGVENSSWAEAAHAVSAKLGINIKGYRV
CCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEE
GLSGDFVVPEDIFSKLYGIENGGAVLIRPDGFIGWRSEKTVVNPDIVLEEVMRNLLCDF
ECCCCEECCHHHHHHHHCCCCCCEEEECCCCCEECCCCCEEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKSNYVPVLIVGGGLSGLASALFLAKHNIEYLLIERHPSTAIHPKAGGLTLRTMELFREL
CCCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEHHHHHHHHHC
GLKKRIKLAGKALENCRGRIAVHTIAEANKEELEQMRATQYGNDEELLQKIEKISPSKQT
CHHHHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHH
ACYQIILEEMMLQEAKTLGGQLSFYHELVSFEQNENGVKAKIRNRETEKESVIHCDYVIA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCHHCEEEEEEEEE
ADGAKSKIREQLGIKTEGRGTIGGYYMNIYFEADLSEFIQGDAFGFSMVLHPEVLGALIP
CCCHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCHHHHHCCCCCCEEEEECHHHHHHHCC
VDNVKKWIYHVAYDPLKGEGPEDFTMERCKQIIEIAIGSTNVESEILSVLPWEAAESTAM
HHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCE
KFQGNRVFLVGDSAHIMPPTGGFGSNTGIQDAHNLAWKLAAVIKGKAKPKLLETYHEERH
EECCCEEEEEECCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SVAKLTTAYASSLLFRAANREEGSLNNMDGLAVTVGYQYCSEAIIDDSVTPHRMDSIELN
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCCEEEEC
GRPGTRAPHLWGTYEGKKVSTLDLFGNSFVLLTGVENSSWAEAAHAVSAKLGINIKGYRV
CCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEE
GLSGDFVVPEDIFSKLYGIENGGAVLIRPDGFIGWRSEKTVVNPDIVLEEVMRNLLCDF
ECCCCEECCHHHHHHHHCCCCCCEEEECCCCCEECCCCCEEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 3-(3-hydroxyphenyl)propionate; NADH; O2 [C]

Specific reaction: 3-(3-hydroxyphenyl)propionate + NADH + O2 = H2O + 3-(2,3-dihydroxyphenyl)propionate + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8253693; 8344517 [H]