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The map label for this gene is dppE [H]

Identifier: 218231654

GI number: 218231654

Start: 1774241

End: 1775869

Strand: Direct

Name: dppE [H]

Synonym: BCB4264_A1867

Alternate gene names: 218231654

Gene position: 1774241-1775869 (Clockwise)

Preceding gene: 218233043

Following gene: 218236009

Centisome position: 32.74

GC content: 33.82

Gene sequence:

>1629_bases
ATGAAGCGAAAAAAGAGCCATTTAATGGTAATGGCACTTGTTACATCTTTATTATTAACAGCTTGTAATAATAAAGCGGA
TAAAAGTGACATAGAGGTTAAAAAACAAGTGTTAAATGTAACAGTATCAGAAGAAGTTCCTTCTCTGGACACTGTGAAAA
CAACAGATGGTACATCAGCACACATTATGCAGAATATATTTGAAGGGTTATATGTATTAAACGATCAAGATCAGCCTACT
CCAGCCATAGCAAAATCGTTTAAAAGAAGTGAAGATGGTAAAAAATATACATTTGACTTGCGTAAAGATGCAAAATGGTC
AAATGGGGATAATGTAACAGCAAATGATTTTATATTTGCTTGGAAACGTGCAATTAACCCTGAAACAGCCTCTCAATATG
CGTCCATGCTCTTTTATGTAAAAAATGCGAAAGAGATCAATAAGGGAACAATGCCTCTTGATGCACTTGGGGTTAAAGCG
ATAAATAATTATACGTTAGAAGTTGAACTCGAACAGCCAGTTCCGTATTTTTTACAGTTGTTAGCACTACCTATATACTT
ACCACAGCATGAATCATTTTTGAAAGAACAAGGAAACAATTATGCATTGGAACCTAGTAATCTCATATATAACGGTCCAT
TTGTATTAGAAAAATGGAAGCATGAACAAGAGTTTCAATTAAAGAAAAATACTACATATTGGGATCGAAAGAAAGTGAAA
TTAGATGAAATAAACTTTCATATCCTAAAGGATACAATGACAGCTGTAAATTTATATGAAGCCGGAGATTTGGATCGAGT
ACCTATTAATTCGCAAGTTGTAGACAAGTATAAAGGGAATAAGGAATTACATATGTCGAGTGATCCTGGAATTGCTATGC
TTCGTTTTAATGAAAAAAATAACGCGTTAGCAAATAAAAAGGTGCGTCAATCTATTTCATTAGCGTTAAATAAAGATGAT
TTCGTTGCTCACTTTATTAATAACGGAGCAAAACCTGCAAGTGGACTTGTACCAGTTGGTCATGTAAATGAAGTGACTGG
TAAAGATTTTAGAAAAGAAAATGGAGATATTTCCTCATATGATTTGCAAAATGCGAAAAAACTTTGGGAAGAAGCGAAAA
AAGAGCTTGGGGTAGAACAAGTAAACCTAGGGTTCTTAACGTTCGAACAAGATAACGCAATACGTATGGCAGAATATATA
AAAGGTGATTTAGAGAAGAATTTGCAAGGACTCGCGATACAAATTAAACAACAGCCATTTAAGCAAAAATTACAGTTAGA
ACAAATAGGTGATTACGATATAACTATGGCAAATTGGGGACCTGACTATAAAGACCCAATTAGTTATTTAGAGTTATTTA
CGACAGGGAATCCGAATAATAAAATGAATTATTCTAATGTTCGTTACGATGAATTAATAAAGAAAGCGAAAACGGATTTT
GTACTAGATACGGAAAAACGATGGGAAGCGTTGCGAGAAGCCGAGCAGGTATTATTAGAAGATGCTGCGGTGGCGCCGCT
TTATCATATTGGCTCAGCATATGTACAAAAGGATTATGTAAAAGGAATTGAAAAGCATCAATTTGGTGGTATTTATACTT
ATAAGAATGCTTATATTGCTAATGAATAA

Upstream 100 bases:

>100_bases
TGAACGAATAAATATTCAAAAGAATGTCGCATCTTTCTGTTAGTATTTCTGCTATAATATATTACGCTTTATAATATTTT
ATATTTAAGGAGAACAACTC

Downstream 100 bases:

>100_bases
ATACAAAAAACCTTACTTTTTAAAAGTAAGGTTTTTTACACATAAATTCTATTAAACTGATTTTAATAAAGCGTAAAAAT
TCGTATCATATGGGATATCA

Product: putative oligopeptide ABC transporter, oligopeptide-binding protein

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MKRKKSHLMVMALVTSLLLTACNNKADKSDIEVKKQVLNVTVSEEVPSLDTVKTTDGTSAHIMQNIFEGLYVLNDQDQPT
PAIAKSFKRSEDGKKYTFDLRKDAKWSNGDNVTANDFIFAWKRAINPETASQYASMLFYVKNAKEINKGTMPLDALGVKA
INNYTLEVELEQPVPYFLQLLALPIYLPQHESFLKEQGNNYALEPSNLIYNGPFVLEKWKHEQEFQLKKNTTYWDRKKVK
LDEINFHILKDTMTAVNLYEAGDLDRVPINSQVVDKYKGNKELHMSSDPGIAMLRFNEKNNALANKKVRQSISLALNKDD
FVAHFINNGAKPASGLVPVGHVNEVTGKDFRKENGDISSYDLQNAKKLWEEAKKELGVEQVNLGFLTFEQDNAIRMAEYI
KGDLEKNLQGLAIQIKQQPFKQKLQLEQIGDYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNVRYDELIKKAKTDF
VLDTEKRWEALREAEQVLLEDAAVAPLYHIGSAYVQKDYVKGIEKHQFGGIYTYKNAYIANE

Sequences:

>Translated_542_residues
MKRKKSHLMVMALVTSLLLTACNNKADKSDIEVKKQVLNVTVSEEVPSLDTVKTTDGTSAHIMQNIFEGLYVLNDQDQPT
PAIAKSFKRSEDGKKYTFDLRKDAKWSNGDNVTANDFIFAWKRAINPETASQYASMLFYVKNAKEINKGTMPLDALGVKA
INNYTLEVELEQPVPYFLQLLALPIYLPQHESFLKEQGNNYALEPSNLIYNGPFVLEKWKHEQEFQLKKNTTYWDRKKVK
LDEINFHILKDTMTAVNLYEAGDLDRVPINSQVVDKYKGNKELHMSSDPGIAMLRFNEKNNALANKKVRQSISLALNKDD
FVAHFINNGAKPASGLVPVGHVNEVTGKDFRKENGDISSYDLQNAKKLWEEAKKELGVEQVNLGFLTFEQDNAIRMAEYI
KGDLEKNLQGLAIQIKQQPFKQKLQLEQIGDYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNVRYDELIKKAKTDF
VLDTEKRWEALREAEQVLLEDAAVAPLYHIGSAYVQKDYVKGIEKHQFGGIYTYKNAYIANE
>Mature_542_residues
MKRKKSHLMVMALVTSLLLTACNNKADKSDIEVKKQVLNVTVSEEVPSLDTVKTTDGTSAHIMQNIFEGLYVLNDQDQPT
PAIAKSFKRSEDGKKYTFDLRKDAKWSNGDNVTANDFIFAWKRAINPETASQYASMLFYVKNAKEINKGTMPLDALGVKA
INNYTLEVELEQPVPYFLQLLALPIYLPQHESFLKEQGNNYALEPSNLIYNGPFVLEKWKHEQEFQLKKNTTYWDRKKVK
LDEINFHILKDTMTAVNLYEAGDLDRVPINSQVVDKYKGNKELHMSSDPGIAMLRFNEKNNALANKKVRQSISLALNKDD
FVAHFINNGAKPASGLVPVGHVNEVTGKDFRKENGDISSYDLQNAKKLWEEAKKELGVEQVNLGFLTFEQDNAIRMAEYI
KGDLEKNLQGLAIQIKQQPFKQKLQLEQIGDYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNVRYDELIKKAKTDF
VLDTEKRWEALREAEQVLLEDAAVAPLYHIGSAYVQKDYVKGIEKHQFGGIYTYKNAYIANE

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation [H]

COG id: COG4166

COG function: function code E; ABC-type oligopeptide transport system, periplasmic component

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787495, Length=547, Percent_Identity=30.7129798903108, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI87081878, Length=535, Percent_Identity=27.8504672897196, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1789397, Length=523, Percent_Identity=27.3422562141491, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI1789966, Length=479, Percent_Identity=27.348643006263, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787762, Length=467, Percent_Identity=23.3404710920771, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1787052, Length=338, Percent_Identity=25.7396449704142, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787551, Length=578, Percent_Identity=22.4913494809689, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1789887, Length=324, Percent_Identity=25, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: 760 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2360 Molecules/Cell In: Stationary-Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 61843; Mature: 61843

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKKSHLMVMALVTSLLLTACNNKADKSDIEVKKQVLNVTVSEEVPSLDTVKTTDGTSA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCCCEECCCCCHH
HIMQNIFEGLYVLNDQDQPTPAIAKSFKRSEDGKKYTFDLRKDAKWSNGDNVTANDFIFA
HHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHH
WKRAINPETASQYASMLFYVKNAKEINKGTMPLDALGVKAINNYTLEVELEQPVPYFLQL
HHHHCCCHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHEECCEEEEEEECCCCHHHHHH
LALPIYLPQHESFLKEQGNNYALEPSNLIYNGPFVLEKWKHEQEFQLKKNTTYWDRKKVK
HHHHHCCCCHHHHHHHCCCCEEECCCCEEECCCCHHHHCCCCCCEEECCCCCCCCCCCEE
LDEINFHILKDTMTAVNLYEAGDLDRVPINSQVVDKYKGNKELHMSSDPGIAMLRFNEKN
EECCCEEEEEHHHHHHEEEECCCCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEECCCC
NALANKKVRQSISLALNKDDFVAHFINNGAKPASGLVPVGHVNEVTGKDFRKENGDISSY
CCHHHHHHHHHHHHEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHH
DLQNAKKLWEEAKKELGVEQVNLGFLTFEQDNAIRMAEYIKGDLEKNLQGLAIQIKQQPF
HHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCHH
KQKLQLEQIGDYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNVRYDELIKKAKTDF
HHHHHHHHCCCEEEEECCCCCCCCCHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHCCCE
VLDTEKRWEALREAEQVLLEDAAVAPLYHIGSAYVQKDYVKGIEKHQFGGIYTYKNAYIA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEC
NE
CC
>Mature Secondary Structure
MKRKKSHLMVMALVTSLLLTACNNKADKSDIEVKKQVLNVTVSEEVPSLDTVKTTDGTSA
CCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHEEECCCCCCCCCEECCCCCHH
HIMQNIFEGLYVLNDQDQPTPAIAKSFKRSEDGKKYTFDLRKDAKWSNGDNVTANDFIFA
HHHHHHHCCEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHH
WKRAINPETASQYASMLFYVKNAKEINKGTMPLDALGVKAINNYTLEVELEQPVPYFLQL
HHHHCCCHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHEECCEEEEEEECCCCHHHHHH
LALPIYLPQHESFLKEQGNNYALEPSNLIYNGPFVLEKWKHEQEFQLKKNTTYWDRKKVK
HHHHHCCCCHHHHHHHCCCCEEECCCCEEECCCCHHHHCCCCCCEEECCCCCCCCCCCEE
LDEINFHILKDTMTAVNLYEAGDLDRVPINSQVVDKYKGNKELHMSSDPGIAMLRFNEKN
EECCCEEEEEHHHHHHEEEECCCCCCCCCCHHHHHHHCCCCEEEECCCCCEEEEEECCCC
NALANKKVRQSISLALNKDDFVAHFINNGAKPASGLVPVGHVNEVTGKDFRKENGDISSY
CCHHHHHHHHHHHHEECCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHH
DLQNAKKLWEEAKKELGVEQVNLGFLTFEQDNAIRMAEYIKGDLEKNLQGLAIQIKQQPF
HHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCHHHHHHHHHHHHCCCCCEEEEEECCHH
KQKLQLEQIGDYDITMANWGPDYKDPISYLELFTTGNPNNKMNYSNVRYDELIKKAKTDF
HHHHHHHHCCCEEEEECCCCCCCCCHHHHHHEEECCCCCCCCCCCCCCHHHHHHHHCCCE
VLDTEKRWEALREAEQVLLEDAAVAPLYHIGSAYVQKDYVKGIEKHQFGGIYTYKNAYIA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEC
NE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1766370; 9384377 [H]