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The map label for this gene is gmuR [H]

Identifier: 218231227

GI number: 218231227

Start: 3291443

End: 3292180

Strand: Reverse

Name: gmuR [H]

Synonym: BCB4264_A3412

Alternate gene names: 218231227

Gene position: 3292180-3291443 (Counterclockwise)

Preceding gene: 218233376

Following gene: 218231257

Centisome position: 60.75

GC content: 39.97

Gene sequence:

>738_bases
ATGGCAAGCGGATCAACACAAGTAAAATACCTCGGCATTTATCAAAAGATTAAACAGCAAATTTTAGGTGGTGAATATAA
AATCAACGAAAAAATTCCGAGTAGCCCCGTCCTTGCTGAAGAATTTGGTGTTTCAGCCCTTACTATTAAGAAAGCGCTGG
ATCTATTAGTTAGAGATGGCTACATCATCCGCCGGCGCGGAAGTGGAACAGTGGTGCAAGATTGGCGTCAACAGGAAAAG
GCACGAATGATTCAAACTTTAACGGGTACGAAAGCTGTATACGGCAGTGAGGTAGAAAGTAAAATTATCGAGTTTGTGAT
TGTTGGGGCTGATGAAGTAGTTGCTGAGAAATTGGGAGTTTCAATCGGTGATTTCGTCTATAAAATCATTCGCCTCCGCA
TCATTCACAGCATTCCGACGATTATGGAGCATACATGGATGCCAATTTCGGTTATCCCAGGTGTTGAGGCTTCTGTTTTA
GAGGAGTCGATATACTCACATATTCAAAATAAACTTGGTCTTGAAGTAGGGACATCTGTTGTCAGGGTTAAAGGAATTCG
CCCAGATGATAGGGAAAAGCAGTTTATGAACTTAACAAATCAGGATTTCCTAATGCGAGTTGAACAAGTAGCTTACTTAA
CGGATGGACGAACTTTTGAATATTCTTATGCAGATCATCTACCCGAAACCTTTGAGTTTGAAACAGTCATTACTGCAAAA
AATTATAAAGAGATATAA

Upstream 100 bases:

>100_bases
TAGAAAATGGATTTGCTGCCCCATCACCTTCAGTTTACAAACTTGAGGCTTTACATTTGAATGAATAGAAGAGAGTTTGC
AGTATAAAGGAGGTATGAAA

Downstream 100 bases:

>100_bases
AAATCGGTTGAGGCAAGTATTGTCTCAACTGCTCCTATTATACGTTAATAGAATGAATCCAAGACTTAACATTTGATTTA
TAGAACTGTAAAGTTTAAAA

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: Glucomannan utilization operon repressor; Glucomannan utilization protein R [H]

Number of amino acids: Translated: 245; Mature: 244

Protein sequence:

>245_residues
MASGSTQVKYLGIYQKIKQQILGGEYKINEKIPSSPVLAEEFGVSALTIKKALDLLVRDGYIIRRRGSGTVVQDWRQQEK
ARMIQTLTGTKAVYGSEVESKIIEFVIVGADEVVAEKLGVSIGDFVYKIIRLRIIHSIPTIMEHTWMPISVIPGVEASVL
EESIYSHIQNKLGLEVGTSVVRVKGIRPDDREKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVITAK
NYKEI

Sequences:

>Translated_245_residues
MASGSTQVKYLGIYQKIKQQILGGEYKINEKIPSSPVLAEEFGVSALTIKKALDLLVRDGYIIRRRGSGTVVQDWRQQEK
ARMIQTLTGTKAVYGSEVESKIIEFVIVGADEVVAEKLGVSIGDFVYKIIRLRIIHSIPTIMEHTWMPISVIPGVEASVL
EESIYSHIQNKLGLEVGTSVVRVKGIRPDDREKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVITAK
NYKEI
>Mature_244_residues
ASGSTQVKYLGIYQKIKQQILGGEYKINEKIPSSPVLAEEFGVSALTIKKALDLLVRDGYIIRRRGSGTVVQDWRQQEKA
RMIQTLTGTKAVYGSEVESKIIEFVIVGADEVVAEKLGVSIGDFVYKIIRLRIIHSIPTIMEHTWMPISVIPGVEASVLE
ESIYSHIQNKLGLEVGTSVVRVKGIRPDDREKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVITAKN
YKEI

Specific function: Transcriptional repressor of the gmuBACDREFG operon which is involved in the uptake and degradation of glucomannan [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=234, Percent_Identity=26.0683760683761, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790118, Length=218, Percent_Identity=28.8990825688073, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87082252, Length=209, Percent_Identity=24.8803827751196, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790540, Length=225, Percent_Identity=24.8888888888889, Blast_Score=67, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27722; Mature: 27591

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGSTQVKYLGIYQKIKQQILGGEYKINEKIPSSPVLAEEFGVSALTIKKALDLLVRDG
CCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCC
YIIRRRGSGTVVQDWRQQEKARMIQTLTGTKAVYGSEVESKIIEFVIVGADEVVAEKLGV
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHEEEECCHHHHHHHHCC
SIGDFVYKIIRLRIIHSIPTIMEHTWMPISVIPGVEASVLEESIYSHIQNKLGLEVGTSV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHCHHHCCCE
VRVKGIRPDDREKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVITAK
EEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECHHHCCCCCEEEEEEEECC
NYKEI
CCCCC
>Mature Secondary Structure 
ASGSTQVKYLGIYQKIKQQILGGEYKINEKIPSSPVLAEEFGVSALTIKKALDLLVRDG
CCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCC
YIIRRRGSGTVVQDWRQQEKARMIQTLTGTKAVYGSEVESKIIEFVIVGADEVVAEKLGV
EEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHEEEECCHHHHHHHHCC
SIGDFVYKIIRLRIIHSIPTIMEHTWMPISVIPGVEASVLEESIYSHIQNKLGLEVGTSV
CHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHHCHHHCCCE
VRVKGIRPDDREKQFMNLTNQDFLMRVEQVAYLTDGRTFEYSYADHLPETFEFETVITAK
EEEECCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECHHHCCCCCEEEEEEEECC
NYKEI
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377 [H]