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The map label for this gene is pepC [H]

Identifier: 213693269

GI number: 213693269

Start: 2717103

End: 2718614

Strand: Direct

Name: pepC [H]

Synonym: Blon_2423

Alternate gene names: 213693269

Gene position: 2717103-2718614 (Clockwise)

Preceding gene: 213693264

Following gene: 213693270

Centisome position: 95.92

GC content: 63.29

Gene sequence:

>1512_bases
ATGACGACAGACGCCAGCGCACGGGCCATCAAACCCGAACTTCTGCGTACGTACACCGAAGACTTCAACAAGGACCGCGC
CAACCTGATCGCGGCGGACGCGGCGGTTTCGGCCGGCGTGCTCAAGGCGGCCACCGACTATCGCGGCGTACGTGCGCTGC
CGCGCGACTTCTCCATCGAACTCAAGCAGGGTTCGATCACCAATCAGGAGCGTTCCGGCCGTTGCTGGATGTTCGCCTCC
CTGAACACGCTGCGTTACGAACTCATGCATCGCTGGAATCTTGAGGATTTCGAGTTCTCCGAGACCTACCTGTTCTTCTG
GGACGCGATGGAGAAGTCGAACACTTATCTGGAGAACGTGCTGCGCACGCTCGACGAGGCGACCGATTCGCGTCTGTTCG
AAGCCATCAACTGGGGCCCGTCCGACGACGGCGGCTGGTGGCAAATGTTCGCCGCCCTGGTGAACAAGTACGGCCTGGTG
CCCAAGAGCGCCTACCCGGAGTCCGAGAACTCCCGTAATTCCGATGATTTCAAGCAGTACCTCAACTCCAAGCTGCGCGA
GTTCGCAGCCGAGCTGCGCCGCCGTTCGGTTGCGGGCGCTGGCGAGGACGAGCTGCGCACGCTGAAGGACGAGTACATGG
GCACCGTGTACCGCATCTGCGCCGTGTCGCTTGGCGAGCCGCCGGAGAAGTTCGACTTCTTCGCGCGCACCAAGGATGAT
GATGAGGATAAGAAGGGCGAGGCCTGCAAGTGCAAGGCCGAGGCCGACGCAGACGGCAAGGCCGAATCCTGCAAGTGCGG
CGACTCCTGCAAATGCGAGGGCAAATCCGACGCCAAGGCCTGCAAGTCCGACAAGCCGAAAACCGGCAAGGACGAGCGCC
CGCAGATTCGCGAGATCGGCATCACCCCGCTTGAGTTCTACAAGAAGTACGTGCCGGTGGACGTCAACGATTTCGTGACG
CTGGCCAACGCCCCGCTCAAGAACCGCCCGTTCAACCAGCGCTACCGCATCCGCTTCAGCGCGAACGTGGCCGAGGCTGG
CGATATGGAATTCGTCAACGTGCCGCTGGACGTGTTCAAGAAGGCCGCGCTTGACCAGCTCACCGCCGGCCACCCGATCT
GGCTCGCCTGCGACTGCACGCAGTTCGCGCTGCGCAAGGACGGTTTCTTCGACCAGTCCGTGGTGCGCGTCGACCAGCTG
TTCGGCACCGAATTCACCGGCGACAAGGCCCACGGCCTCGAATACGGCGACAGCCCAAGCAACCACGCGATGACCTTCAC
CGGCGTGAACCTCGGCGAGGACGGCAAGCCGAACCGCTGGAAGGTGGAGAACAGCTGGGGCAAGGACGCCGGCAAGGACG
GCTACTACGTCATGTCCGACGCCTGGTTCGACCGTTACGTCACCGAGCTCATCATCCGCAAGGAATACCTCGACGACGCC
ACCCGCGCCCTGCTCGCCGCCGAACCGGTCGAGCTCGACCCCTGGCAGCCCCTCACCCGCCGCTGCCGCTGA

Upstream 100 bases:

>100_bases
TTATACTTCCGTGTCAGTAGTCCGCCGACTCGGATGGTGACAGTCCCCGCCGCCGGCAGCAGAATATCCATCAGCATCAT
CAGCATCAGACAGGGGCATC

Downstream 100 bases:

>100_bases
CATTCCGCTGGCGGGAGCATATATTGAATGCCCCTTCTCTCTGTTCAGAGAGAAGGGGCATTACGTTATGCGAGTACGTC
CGGCCGCACCTATTCGAGAC

Product: Bleomycin hydrolase

Products: NA

Alternate protein names: Bleomycin hydrolase [H]

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MTTDASARAIKPELLRTYTEDFNKDRANLIAADAAVSAGVLKAATDYRGVRALPRDFSIELKQGSITNQERSGRCWMFAS
LNTLRYELMHRWNLEDFEFSETYLFFWDAMEKSNTYLENVLRTLDEATDSRLFEAINWGPSDDGGWWQMFAALVNKYGLV
PKSAYPESENSRNSDDFKQYLNSKLREFAAELRRRSVAGAGEDELRTLKDEYMGTVYRICAVSLGEPPEKFDFFARTKDD
DEDKKGEACKCKAEADADGKAESCKCGDSCKCEGKSDAKACKSDKPKTGKDERPQIREIGITPLEFYKKYVPVDVNDFVT
LANAPLKNRPFNQRYRIRFSANVAEAGDMEFVNVPLDVFKKAALDQLTAGHPIWLACDCTQFALRKDGFFDQSVVRVDQL
FGTEFTGDKAHGLEYGDSPSNHAMTFTGVNLGEDGKPNRWKVENSWGKDAGKDGYYVMSDAWFDRYVTELIIRKEYLDDA
TRALLAAEPVELDPWQPLTRRCR

Sequences:

>Translated_503_residues
MTTDASARAIKPELLRTYTEDFNKDRANLIAADAAVSAGVLKAATDYRGVRALPRDFSIELKQGSITNQERSGRCWMFAS
LNTLRYELMHRWNLEDFEFSETYLFFWDAMEKSNTYLENVLRTLDEATDSRLFEAINWGPSDDGGWWQMFAALVNKYGLV
PKSAYPESENSRNSDDFKQYLNSKLREFAAELRRRSVAGAGEDELRTLKDEYMGTVYRICAVSLGEPPEKFDFFARTKDD
DEDKKGEACKCKAEADADGKAESCKCGDSCKCEGKSDAKACKSDKPKTGKDERPQIREIGITPLEFYKKYVPVDVNDFVT
LANAPLKNRPFNQRYRIRFSANVAEAGDMEFVNVPLDVFKKAALDQLTAGHPIWLACDCTQFALRKDGFFDQSVVRVDQL
FGTEFTGDKAHGLEYGDSPSNHAMTFTGVNLGEDGKPNRWKVENSWGKDAGKDGYYVMSDAWFDRYVTELIIRKEYLDDA
TRALLAAEPVELDPWQPLTRRCR
>Mature_502_residues
TTDASARAIKPELLRTYTEDFNKDRANLIAADAAVSAGVLKAATDYRGVRALPRDFSIELKQGSITNQERSGRCWMFASL
NTLRYELMHRWNLEDFEFSETYLFFWDAMEKSNTYLENVLRTLDEATDSRLFEAINWGPSDDGGWWQMFAALVNKYGLVP
KSAYPESENSRNSDDFKQYLNSKLREFAAELRRRSVAGAGEDELRTLKDEYMGTVYRICAVSLGEPPEKFDFFARTKDDD
EDKKGEACKCKAEADADGKAESCKCGDSCKCEGKSDAKACKSDKPKTGKDERPQIREIGITPLEFYKKYVPVDVNDFVTL
ANAPLKNRPFNQRYRIRFSANVAEAGDMEFVNVPLDVFKKAALDQLTAGHPIWLACDCTQFALRKDGFFDQSVVRVDQLF
GTEFTGDKAHGLEYGDSPSNHAMTFTGVNLGEDGKPNRWKVENSWGKDAGKDGYYVMSDAWFDRYVTELIIRKEYLDDAT
RALLAAEPVELDPWQPLTRRCR

Specific function: Unknown

COG id: COG3579

COG function: function code E; Aminopeptidase C

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C1 family [H]

Homologues:

Organism=Homo sapiens, GI4557367, Length=502, Percent_Identity=30.0796812749004, Blast_Score=262, Evalue=7e-70,
Organism=Saccharomyces cerevisiae, GI6324090, Length=439, Percent_Identity=29.6127562642369, Blast_Score=204, Evalue=4e-53,
Organism=Drosophila melanogaster, GI161077630, Length=416, Percent_Identity=29.0865384615385, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI161077632, Length=241, Percent_Identity=32.7800829875519, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24640588, Length=241, Percent_Identity=32.7800829875519, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI20130175, Length=436, Percent_Identity=25, Blast_Score=114, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000169
- InterPro:   IPR004134 [H]

Pfam domain/function: PF03051 Peptidase_C1_2 [H]

EC number: =3.4.22.40 [H]

Molecular weight: Translated: 57123; Mature: 56992

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00139 THIOL_PROTEASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDASARAIKPELLRTYTEDFNKDRANLIAADAAVSAGVLKAATDYRGVRALPRDFSIE
CCCCCCCHHCCHHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHHHHCCCHHCCCCCCEEE
LKQGSITNQERSGRCWMFASLNTLRYELMHRWNLEDFEFSETYLFFWDAMEKSNTYLENV
EECCCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCEEEEEEECHHHCHHHHHHH
LRTLDEATDSRLFEAINWGPSDDGGWWQMFAALVNKYGLVPKSAYPESENSRNSDDFKQY
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
LNSKLREFAAELRRRSVAGAGEDELRTLKDEYMGTVYRICAVSLGEPPEKFDFFARTKDD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
DEDKKGEACKCKAEADADGKAESCKCGDSCKCEGKSDAKACKSDKPKTGKDERPQIREIG
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHCC
ITPLEFYKKYVPVDVNDFVTLANAPLKNRPFNQRYRIRFSANVAEAGDMEFVNVPLDVFK
CCHHHHHHHHCCCCHHHHHEECCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCHHHHH
KAALDQLTAGHPIWLACDCTQFALRKDGFFDQSVVRVDQLFGTEFTGDKAHGLEYGDSPS
HHHHHHHCCCCCEEEEECCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NHAMTFTGVNLGEDGKPNRWKVENSWGKDAGKDGYYVMSDAWFDRYVTELIIRKEYLDDA
CCEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
TRALLAAEPVELDPWQPLTRRCR
HHHHHHCCCCCCCCCCHHHHCCC
>Mature Secondary Structure 
TTDASARAIKPELLRTYTEDFNKDRANLIAADAAVSAGVLKAATDYRGVRALPRDFSIE
CCCCCCHHCCHHHHHHHHHHHCCCHHHEEEHHHHHHHHHHHHHHHCCCHHCCCCCCEEE
LKQGSITNQERSGRCWMFASLNTLRYELMHRWNLEDFEFSETYLFFWDAMEKSNTYLENV
EECCCCCCCCCCCCEEEEECHHHHHHHHHHHCCCCCCCCCCEEEEEEECHHHCHHHHHHH
LRTLDEATDSRLFEAINWGPSDDGGWWQMFAALVNKYGLVPKSAYPESENSRNSDDFKQY
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHH
LNSKLREFAAELRRRSVAGAGEDELRTLKDEYMGTVYRICAVSLGEPPEKFDFFARTKDD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
DEDKKGEACKCKAEADADGKAESCKCGDSCKCEGKSDAKACKSDKPKTGKDERPQIREIG
CCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCHHHCC
ITPLEFYKKYVPVDVNDFVTLANAPLKNRPFNQRYRIRFSANVAEAGDMEFVNVPLDVFK
CCHHHHHHHHCCCCHHHHHEECCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCHHHHH
KAALDQLTAGHPIWLACDCTQFALRKDGFFDQSVVRVDQLFGTEFTGDKAHGLEYGDSPS
HHHHHHHCCCCCEEEEECCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NHAMTFTGVNLGEDGKPNRWKVENSWGKDAGKDGYYVMSDAWFDRYVTELIIRKEYLDDA
CCEEEEEECCCCCCCCCCCEEECCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
TRALLAAEPVELDPWQPLTRRCR
HHHHHHCCCCCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]