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The map label for this gene is mutT1 [H]

Identifier: 213693179

GI number: 213693179

Start: 2591409

End: 2592608

Strand: Direct

Name: mutT1 [H]

Synonym: Blon_2329

Alternate gene names: 213693179

Gene position: 2591409-2592608 (Clockwise)

Preceding gene: 213693178

Following gene: 213693180

Centisome position: 91.48

GC content: 61.83

Gene sequence:

>1200_bases
ATGAGACGAATCGTGGAAGCCGCCGGCGGTATTCTGTACCGGTGGAAGGATGATGCCGAGCCGACGCAGGCATCATCTCC
ATCAGTGAAATCCAATATTGCCACCGATGGCACCATCATCGCGAACACCACGGATTCTGACGGCGAGACCACGGCAGCAC
CCGGCGCATCGGACGCGGCTCCCGCCCCGGACCCGGCACAGGCCGACAGCCCAGCCACGGCGGACAACGTACTCAACCGC
ATCGAACTGTGCGTCGTGCATCGCCCGAAATACGACGACTGGAGCTGGCCGAAAGGCAAGGTCGATCCAAACGAATCACA
CCGGCATGCCGCCGTGCGCGAGATCGGCGAGGAATCGGGCCTGTCCGTGGAGCTTGGCCCTTATCTGGGTGACATCGAGT
ACCCGCTGTCCGAAGAGGGCATCAAACAGCGCCATACCAAGGATCGGTCGGCGGACACCAAGCACATCCAGTTCTGGATG
GCCACGCCAATCAGCGCCATCGACAATCTGCGGCGCACCCATGCGTTCGGCCCGGTGCATCGGGCGGACATCGGCGAAAT
CGACGAAGTCCTGTGGTTGACGCCGGCTAAGGCCCGCAAGAAACTCAGCCATTCCACCGATAAGGACATCCTTGCGCTAT
TCGTTGACCGGGTGCAGGAGGGCGCGCTTGACGCCGTGCCGGTGATTATCGTGCGCCACGGCAAGGCAGAAGCGCGCAAG
CTGTGGAAGGGCTCGGACGAGAACCGTCCGATCACGCCGCGCGGCGCGGCTGCGGCATACGCGCTGAACCGCGAGCTGGC
GTGTTTCAATCCGACCCGACTGGCCACGTCGCCTTGGGTGCGCTGCCAGGAGACATTGGAGATGTTCGCGTGGCAGACCG
GACGAGACATGGTTCATCTCGACCCGCTCACCGAAGATGCATACGCCGCTGCGCCGGACACCGCATGGGAGTGTCTACTC
AGCGAAATCGAGTTCGCACTTGAGCGCCGTCAGCCTACAGCGATATGCATGCACCGGCCAGTGATTGGGGGTATGTTCGA
ACACCTGCGCAGCATGTGCGTTGCGCCGTCTCTGAGCAAACGCCTGATTGCCAAGACACCGTTTATGCCGACCGGCACGG
CGGTGGCGCTGTTCGTCACTCCGACGCCTCATGGTCCCAAAATCATCGATATTCAGAAGGTTCAACCGCTTGTCTACTAG

Upstream 100 bases:

>100_bases
CTCCTCTTTCGAGAGGATGCCGGGCATCGTCGTTCCATGCGCAAAACTACGTAGCAGCGGTCCAACGTGACCTACAATAC
AAGAGATGGGTACGAACAGT

Downstream 100 bases:

>100_bases
ACCCGCATTTCCTGATTCATCCAACTCCTCGGCCGCTGCCGCCGCGGCTCATGCCGCGCACAATGGTGCCGCCGGCAGTC
TGGGCCCAGGCTTCGGCTCG

Product: phosphohistidine phosphatase, SixA

Products: NA

Alternate protein names: 7,8-dihydro-8-oxoguanine-triphosphatase; 8-oxo-dGTPase; dGTP pyrophosphohydrolase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MRRIVEAAGGILYRWKDDAEPTQASSPSVKSNIATDGTIIANTTDSDGETTAAPGASDAAPAPDPAQADSPATADNVLNR
IELCVVHRPKYDDWSWPKGKVDPNESHRHAAVREIGEESGLSVELGPYLGDIEYPLSEEGIKQRHTKDRSADTKHIQFWM
ATPISAIDNLRRTHAFGPVHRADIGEIDEVLWLTPAKARKKLSHSTDKDILALFVDRVQEGALDAVPVIIVRHGKAEARK
LWKGSDENRPITPRGAAAAYALNRELACFNPTRLATSPWVRCQETLEMFAWQTGRDMVHLDPLTEDAYAAAPDTAWECLL
SEIEFALERRQPTAICMHRPVIGGMFEHLRSMCVAPSLSKRLIAKTPFMPTGTAVALFVTPTPHGPKIIDIQKVQPLVY

Sequences:

>Translated_399_residues
MRRIVEAAGGILYRWKDDAEPTQASSPSVKSNIATDGTIIANTTDSDGETTAAPGASDAAPAPDPAQADSPATADNVLNR
IELCVVHRPKYDDWSWPKGKVDPNESHRHAAVREIGEESGLSVELGPYLGDIEYPLSEEGIKQRHTKDRSADTKHIQFWM
ATPISAIDNLRRTHAFGPVHRADIGEIDEVLWLTPAKARKKLSHSTDKDILALFVDRVQEGALDAVPVIIVRHGKAEARK
LWKGSDENRPITPRGAAAAYALNRELACFNPTRLATSPWVRCQETLEMFAWQTGRDMVHLDPLTEDAYAAAPDTAWECLL
SEIEFALERRQPTAICMHRPVIGGMFEHLRSMCVAPSLSKRLIAKTPFMPTGTAVALFVTPTPHGPKIIDIQKVQPLVY
>Mature_399_residues
MRRIVEAAGGILYRWKDDAEPTQASSPSVKSNIATDGTIIANTTDSDGETTAAPGASDAAPAPDPAQADSPATADNVLNR
IELCVVHRPKYDDWSWPKGKVDPNESHRHAAVREIGEESGLSVELGPYLGDIEYPLSEEGIKQRHTKDRSADTKHIQFWM
ATPISAIDNLRRTHAFGPVHRADIGEIDEVLWLTPAKARKKLSHSTDKDILALFVDRVQEGALDAVPVIIVRHGKAEARK
LWKGSDENRPITPRGAAAAYALNRELACFNPTRLATSPWVRCQETLEMFAWQTGRDMVHLDPLTEDAYAAAPDTAWECLL
SEIEFALERRQPTAICMHRPVIGGMFEHLRSMCVAPSLSKRLIAKTPFMPTGTAVALFVTPTPHGPKIIDIQKVQPLVY

Specific function: May be involved in the GO system responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8- oxoguanine, 8-oxo-dGTP) from DNA and the nucleotide pool. 8-oxo- dGTP is inserted opposite dA and dC residues of template DNA with almost equa

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX; PF00300 PGAM [H]

EC number: NA

Molecular weight: Translated: 43937; Mature: 43937

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRIVEAAGGILYRWKDDAEPTQASSPSVKSNIATDGTIIANTTDSDGETTAAPGASDAA
CCCHHHHCCCEEEEECCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCC
PAPDPAQADSPATADNVLNRIELCVVHRPKYDDWSWPKGKVDPNESHRHAAVREIGEESG
CCCCCCCCCCCCCHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LSVELGPYLGDIEYPLSEEGIKQRHTKDRSADTKHIQFWMATPISAIDNLRRTHAFGPVH
CEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCC
RADIGEIDEVLWLTPAKARKKLSHSTDKDILALFVDRVQEGALDAVPVIIVRHGKAEARK
CCCCCCHHHHEEECCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHH
LWKGSDENRPITPRGAAAAYALNRELACFNPTRLATSPWVRCQETLEMFAWQTGRDMVHL
HHCCCCCCCCCCCCCCHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
DPLTEDAYAAAPDTAWECLLSEIEFALERRQPTAICMHRPVIGGMFEHLRSMCVAPSLSK
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCHHH
RLIAKTPFMPTGTAVALFVTPTPHGPKIIDIQKVQPLVY
HHHHCCCCCCCCCEEEEEEECCCCCCEEEEHHCCCCCCC
>Mature Secondary Structure
MRRIVEAAGGILYRWKDDAEPTQASSPSVKSNIATDGTIIANTTDSDGETTAAPGASDAA
CCCHHHHCCCEEEEECCCCCCCCCCCCCHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCC
PAPDPAQADSPATADNVLNRIELCVVHRPKYDDWSWPKGKVDPNESHRHAAVREIGEESG
CCCCCCCCCCCCCHHHHHHHEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
LSVELGPYLGDIEYPLSEEGIKQRHTKDRSADTKHIQFWMATPISAIDNLRRTHAFGPVH
CEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCC
RADIGEIDEVLWLTPAKARKKLSHSTDKDILALFVDRVQEGALDAVPVIIVRHGKAEARK
CCCCCCHHHHEEECCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHH
LWKGSDENRPITPRGAAAAYALNRELACFNPTRLATSPWVRCQETLEMFAWQTGRDMVHL
HHCCCCCCCCCCCCCCHHHHHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
DPLTEDAYAAAPDTAWECLLSEIEFALERRQPTAICMHRPVIGGMFEHLRSMCVAPSLSK
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHCCCCHHH
RLIAKTPFMPTGTAVALFVTPTPHGPKIIDIQKVQPLVY
HHHHCCCCCCCCCEEEEEEECCCCCCEEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]