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The map label for this gene is kipR [H]

Identifier: 213693176

GI number: 213693176

Start: 2586273

End: 2587073

Strand: Direct

Name: kipR [H]

Synonym: Blon_2326

Alternate gene names: 213693176

Gene position: 2586273-2587073 (Clockwise)

Preceding gene: 213693172

Following gene: 213693178

Centisome position: 91.3

GC content: 63.92

Gene sequence:

>801_bases
ATGACTGATTCCCAAGAAGAACCATTGAACAACAGCTTGACCGAGTCCGAGACGGTTGAAGACACCACCACCAAGGACGA
TGGGGAAATCCATTCCGGCGTTGGCGTCCTTGATAAAACCGTAAAGATTCTTGACGCACTGGAGTCCGGTCCGTCCACGC
TGGGACAGCTTGTGGCCGCCACCGGTCTCGCCCGACCGACCGCACATCGTTTGGCTATTGCACTGGAACGCCACCGTTTC
GTACTGCGCGACCAGCATGGCCGATTCGTACTCGGCTCCCGTTTCGCCGAACTTGCCGCCGCAGCAGGCGAGGATCGTCT
GCTGACCGCCGCCGGCCCTATCCTGCAGACACTGCTCGATCGCACTGGCGAGTCTGCGCAGATTTACCGCCGCCAAGGCG
ATCAGCGCGTGTGCATCGCCGCTGTGGAACGCGCCTCCGGCCTGCGTGATTCCATTCCCGTGGGTGCCATGCTGTCGATG
GAAGCCGGTTCCGCCGCCCAGATTCTTCTGGCTTGGGAGGATTCCGACCGTCTGCACCAGGGATTGCGCCACGCCAAGTT
CACCGCCACCAAGCTGGCCGCCGTACGCAAGCGCGGCTGGTCCGAGTCCGTGAACGAGCGCGAAGAGGGCGTGTGCTCGA
TTTCCGCCCCGATCCGCAACGCCTCCGGCCAGGTCATCGCCGCCATCTCGATTTCTGGCCCGACCGGCCGCATGGGCGCC
GCCCCCGGACGCCGCTATGCGCCGCTGGTGATGGCCGCCGGCAAGTACCTCACCGAGGCACTGGTCAAAGCCGTTCGCTG
A

Upstream 100 bases:

>100_bases
CTTCGGCATCCACGAACGCCCTTTCAACTTCATGACCACCCTGTGAGACACTTCCCTAATTTGCCATTTCACTATGTGAG
ATGGCATAATCGCCCTTATT

Downstream 100 bases:

>100_bases
AACATACCAGTCAATCCAACCGATAGCCCAACCGGCAGAAATCCCGCGTCACAACGAAAGAGACGCGGGATTTCTGCCAC
TAATCGTCCAACACAGCGGA

Product: regulatory protein, IclR

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTDSQEEPLNNSLTESETVEDTTTKDDGEIHSGVGVLDKTVKILDALESGPSTLGQLVAATGLARPTAHRLAIALERHRF
VLRDQHGRFVLGSRFAELAAAAGEDRLLTAAGPILQTLLDRTGESAQIYRRQGDQRVCIAAVERASGLRDSIPVGAMLSM
EAGSAAQILLAWEDSDRLHQGLRHAKFTATKLAAVRKRGWSESVNEREEGVCSISAPIRNASGQVIAAISISGPTGRMGA
APGRRYAPLVMAAGKYLTEALVKAVR

Sequences:

>Translated_266_residues
MTDSQEEPLNNSLTESETVEDTTTKDDGEIHSGVGVLDKTVKILDALESGPSTLGQLVAATGLARPTAHRLAIALERHRF
VLRDQHGRFVLGSRFAELAAAAGEDRLLTAAGPILQTLLDRTGESAQIYRRQGDQRVCIAAVERASGLRDSIPVGAMLSM
EAGSAAQILLAWEDSDRLHQGLRHAKFTATKLAAVRKRGWSESVNEREEGVCSISAPIRNASGQVIAAISISGPTGRMGA
APGRRYAPLVMAAGKYLTEALVKAVR
>Mature_265_residues
TDSQEEPLNNSLTESETVEDTTTKDDGEIHSGVGVLDKTVKILDALESGPSTLGQLVAATGLARPTAHRLAIALERHRFV
LRDQHGRFVLGSRFAELAAAAGEDRLLTAAGPILQTLLDRTGESAQIYRRQGDQRVCIAAVERASGLRDSIPVGAMLSME
AGSAAQILLAWEDSDRLHQGLRHAKFTATKLAAVRKRGWSESVNEREEGVCSISAPIRNASGQVIAAISISGPTGRMGAA
PGRRYAPLVMAAGKYLTEALVKAVR

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786715, Length=227, Percent_Identity=30.8370044052863, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI87082359, Length=246, Percent_Identity=28.4552845528455, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788581, Length=217, Percent_Identity=28.110599078341, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788131, Length=236, Percent_Identity=26.6949152542373, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786468, Length=242, Percent_Identity=24.7933884297521, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28345; Mature: 28213

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSQEEPLNNSLTESETVEDTTTKDDGEIHSGVGVLDKTVKILDALESGPSTLGQLVAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
TGLARPTAHRLAIALERHRFVLRDQHGRFVLGSRFAELAAAAGEDRLLTAAGPILQTLLD
HCCCCCHHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHCCCCCEEEHHHHHHHHHHH
RTGESAQIYRRQGDQRVCIAAVERASGLRDSIPVGAMLSMEAGSAAQILLAWEDSDRLHQ
CCCCHHHHHHHCCCCEEHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEECCCHHHHH
GLRHAKFTATKLAAVRKRGWSESVNEREEGVCSISAPIRNASGQVIAAISISGPTGRMGA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEECCCCCCCCCEEEEEEECCCCCCCCC
APGRRYAPLVMAAGKYLTEALVKAVR
CCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDSQEEPLNNSLTESETVEDTTTKDDGEIHSGVGVLDKTVKILDALESGPSTLGQLVAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
TGLARPTAHRLAIALERHRFVLRDQHGRFVLGSRFAELAAAAGEDRLLTAAGPILQTLLD
HCCCCCHHHHHHHHHHHHHHEEECCCCCEEHHHHHHHHHHHCCCCCEEEHHHHHHHHHHH
RTGESAQIYRRQGDQRVCIAAVERASGLRDSIPVGAMLSMEAGSAAQILLAWEDSDRLHQ
CCCCHHHHHHHCCCCEEHHHHHHHHCCCCCCCCCCEEEEECCCCCEEEEEEECCCHHHHH
GLRHAKFTATKLAAVRKRGWSESVNEREEGVCSISAPIRNASGQVIAAISISGPTGRMGA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCEEEEECCCCCCCCCEEEEEEECCCCCCCCC
APGRRYAPLVMAAGKYLTEALVKAVR
CCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]