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The map label for this gene is ykgC [H]

Identifier: 213693041

GI number: 213693041

Start: 2426489

End: 2428132

Strand: Direct

Name: ykgC [H]

Synonym: Blon_2188

Alternate gene names: 213693041

Gene position: 2426489-2428132 (Clockwise)

Preceding gene: 213693040

Following gene: 213693043

Centisome position: 85.66

GC content: 61.56

Gene sequence:

>1644_bases
ATGTCCACCAGCACACCCAATGCCATCAGCACGCCCGACACCATCAGCACGCCCAGCACCTCTCCCACTATCACCACCGA
CGCCCTGATCATTGGATTCGGCAAGGGCGGCAAAACCTTGGCCGCCAAGCTCAGCGCAGCCGGCCGCAAGGTCGTCGTCG
CCGAGGCAAGCGCCAACATGTACGGCGGCACCTGCATCAATATCGGATGCTTGCCGTCCAAGTCACTGATTTTGTCCGCC
GAACAGGCGCGGCGGGATGGCGCGAACAGTACTCCCGAAACCCGCGAAGCAGCGTTCGAGGCTGCTATCAAGGAGAAGCG
CCGCGTCACTTCGATGCTGCGCGACAAGAACTATCACAAGCTCGCCGACCAAGACAACATCACCGTAATCACCGGCCACG
CTCACTTCACCGGCCCTCATAGCGTGGAAATCGCCACCGCTGAGGGCCCGGTCGCCGTGACCGCCAGCAAGATCTTCATC
AATACCGGCGCCACGCCGCGCATTCCGGATATTCCCGGTATCCGCACTACGCCCGGCGTCTACACCAGCACTGGACTGAT
GGATCTCGACGATATGCCGCAGCGACTGGCGATTATCGGTTCAGGATTCATTGGACTTGAGTTTGCCTCGATGTTTGCCG
ATTTCGGCACGGCGGTTACCGTGCTGCAGCACAATGCCGAGTTCCTGCCGCGCGAGGATGCGGATGTGGCGGCCGCGATT
CGCGCACAGCTGGAAGCGCAGGGCGTCAAGTTCCTGTTCAACGCGGATACCAAGGCCATCACGCCTGCTGCTGACGGCGG
CGTCAGGTTGTCCGTTGCGGTGAAGGGTATGACTCGCGGTGCATCGCAAGCTTGCGATTCCACCCCCGCCGGCACCGGGA
ACGCTCATACCGATATCACCGGTGCCACCGGCACCACCGACACTGCAACAACCACCAGCCCCACTAGCAACCCGACCGAT
CACGCCACGATGTCACACGTTCAAACGAAACCATCAGACGATGGCGAGCCGCGGTTCGCCGAACCGGCTGAAGCCCGATT
CTGCCTGACCACCGACGCGGTACTGGTGGCCACCGGACGTACGCCGAACGTCGAGGGACTGCATCTTGAGGCGGCTGGCG
TGGAGCTCACCGAACGCGGCGCCGTGAAAGTCGACGAGCTTCTGCGCACCACAGCAGCCGACATTTGGGCTCTGGGCGAT
GTGAACGGCGGCCCGCAGCACACGTACATTTCACTGGACGACTATCGCGTGGTGTGGTCGCAGCTCAATGGTTCCGCCCG
TCCGTACACGGTGAAGGACCGCAAGCATGTGCCGTCGAGCACATTCCTCGCCACGCCTTACTCTCGCGTGGGATTGAATG
AGCGCGAGGCGAAGGCGGCCGGATTGGATTATGTGGTCAAGCGATTGCCGGTGGCCGCTGTGCCGAAGGCCCAGGTAATG
CGGCGACCGGATGGTCTGATGAAGGCGATTGTGGAACGCAATACTGGCCGCATTCTGGGTGCGATGCTGCTTTCCGTCGA
GTCGCACGAGGTGATCAATATCGTCAAGTTGGCGATGGATCTTGACGCGCCGGCCAGCACGTTGCGCGATATAGTGTTCA
CGCATCCGACGATTGCCGAGGCACTGAACGACTTGTTCGCGTAG

Upstream 100 bases:

>100_bases
CGACAACGCTTCGGCAGTCAAAGAAGAAAATCGGCACAGCACGGCGCACAACACATCAGCACAACACACTCTTACCACTC
GAATACGTAAGGAAGTAACC

Downstream 100 bases:

>100_bases
TTTGTCCGCAGAGCACGCCCGCGTAGTGCGACCCGCGTAGTGCGACCCGCGTAGTGCGACCCGCAACAGACTCCCCTAAT
GCGCGCGAAGGTCCTCATCG

Product: pyridine nucleotide-disulphide oxidoreductase dimerisation region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 546

Protein sequence:

>547_residues
MSTSTPNAISTPDTISTPSTSPTITTDALIIGFGKGGKTLAAKLSAAGRKVVVAEASANMYGGTCINIGCLPSKSLILSA
EQARRDGANSTPETREAAFEAAIKEKRRVTSMLRDKNYHKLADQDNITVITGHAHFTGPHSVEIATAEGPVAVTASKIFI
NTGATPRIPDIPGIRTTPGVYTSTGLMDLDDMPQRLAIIGSGFIGLEFASMFADFGTAVTVLQHNAEFLPREDADVAAAI
RAQLEAQGVKFLFNADTKAITPAADGGVRLSVAVKGMTRGASQACDSTPAGTGNAHTDITGATGTTDTATTTSPTSNPTD
HATMSHVQTKPSDDGEPRFAEPAEARFCLTTDAVLVATGRTPNVEGLHLEAAGVELTERGAVKVDELLRTTAADIWALGD
VNGGPQHTYISLDDYRVVWSQLNGSARPYTVKDRKHVPSSTFLATPYSRVGLNEREAKAAGLDYVVKRLPVAAVPKAQVM
RRPDGLMKAIVERNTGRILGAMLLSVESHEVINIVKLAMDLDAPASTLRDIVFTHPTIAEALNDLFA

Sequences:

>Translated_547_residues
MSTSTPNAISTPDTISTPSTSPTITTDALIIGFGKGGKTLAAKLSAAGRKVVVAEASANMYGGTCINIGCLPSKSLILSA
EQARRDGANSTPETREAAFEAAIKEKRRVTSMLRDKNYHKLADQDNITVITGHAHFTGPHSVEIATAEGPVAVTASKIFI
NTGATPRIPDIPGIRTTPGVYTSTGLMDLDDMPQRLAIIGSGFIGLEFASMFADFGTAVTVLQHNAEFLPREDADVAAAI
RAQLEAQGVKFLFNADTKAITPAADGGVRLSVAVKGMTRGASQACDSTPAGTGNAHTDITGATGTTDTATTTSPTSNPTD
HATMSHVQTKPSDDGEPRFAEPAEARFCLTTDAVLVATGRTPNVEGLHLEAAGVELTERGAVKVDELLRTTAADIWALGD
VNGGPQHTYISLDDYRVVWSQLNGSARPYTVKDRKHVPSSTFLATPYSRVGLNEREAKAAGLDYVVKRLPVAAVPKAQVM
RRPDGLMKAIVERNTGRILGAMLLSVESHEVINIVKLAMDLDAPASTLRDIVFTHPTIAEALNDLFA
>Mature_546_residues
STSTPNAISTPDTISTPSTSPTITTDALIIGFGKGGKTLAAKLSAAGRKVVVAEASANMYGGTCINIGCLPSKSLILSAE
QARRDGANSTPETREAAFEAAIKEKRRVTSMLRDKNYHKLADQDNITVITGHAHFTGPHSVEIATAEGPVAVTASKIFIN
TGATPRIPDIPGIRTTPGVYTSTGLMDLDDMPQRLAIIGSGFIGLEFASMFADFGTAVTVLQHNAEFLPREDADVAAAIR
AQLEAQGVKFLFNADTKAITPAADGGVRLSVAVKGMTRGASQACDSTPAGTGNAHTDITGATGTTDTATTTSPTSNPTDH
ATMSHVQTKPSDDGEPRFAEPAEARFCLTTDAVLVATGRTPNVEGLHLEAAGVELTERGAVKVDELLRTTAADIWALGDV
NGGPQHTYISLDDYRVVWSQLNGSARPYTVKDRKHVPSSTFLATPYSRVGLNEREAKAAGLDYVVKRLPVAAVPKAQVMR
RPDGLMKAIVERNTGRILGAMLLSVESHEVINIVKLAMDLDAPASTLRDIVFTHPTIAEALNDLFA

Specific function: Unknown

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI91199540, Length=534, Percent_Identity=26.5917602996255, Blast_Score=171, Evalue=2e-42,
Organism=Homo sapiens, GI50301238, Length=250, Percent_Identity=29.2, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI33519430, Length=197, Percent_Identity=27.4111675126904, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI33519428, Length=197, Percent_Identity=27.4111675126904, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI33519426, Length=197, Percent_Identity=27.4111675126904, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI148277065, Length=197, Percent_Identity=27.4111675126904, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI148277071, Length=197, Percent_Identity=27.4111675126904, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI291045268, Length=226, Percent_Identity=26.1061946902655, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI291045266, Length=226, Percent_Identity=26.1061946902655, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI87081717, Length=199, Percent_Identity=54.7738693467337, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI1786307, Length=530, Percent_Identity=25.8490566037736, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87082354, Length=210, Percent_Identity=30, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1789915, Length=229, Percent_Identity=27.9475982532751, Blast_Score=86, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI32565766, Length=539, Percent_Identity=25.6029684601113, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71982272, Length=245, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71983429, Length=189, Percent_Identity=26.984126984127, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI71983419, Length=189, Percent_Identity=26.984126984127, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17557007, Length=267, Percent_Identity=25.0936329588015, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6325240, Length=268, Percent_Identity=29.1044776119403, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321091, Length=196, Percent_Identity=27.5510204081633, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6325166, Length=246, Percent_Identity=28.4552845528455, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI21358499, Length=196, Percent_Identity=31.6326530612245, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17737741, Length=302, Percent_Identity=26.8211920529801, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24640551, Length=275, Percent_Identity=28.3636363636364, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640549, Length=275, Percent_Identity=28.3636363636364, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24640553, Length=275, Percent_Identity=28.3636363636364, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: NA

Molecular weight: Translated: 57640; Mature: 57508

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00076 PYRIDINE_REDOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTSTPNAISTPDTISTPSTSPTITTDALIIGFGKGGKTLAAKLSAAGRKVVVAEASANM
CCCCCCCCCCCCCCCCCCCCCCCEEECEEEEEECCCCCHHHHHHHCCCCEEEEEECCCCC
YGGTCINIGCLPSKSLILSAEQARRDGANSTPETREAAFEAAIKEKRRVTSMLRDKNYHK
CCCEEEEEECCCCCCEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LADQDNITVITGHAHFTGPHSVEIATAEGPVAVTASKIFINTGATPRIPDIPGIRTTPGV
CCCCCCEEEEECCCEECCCCEEEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCC
YTSTGLMDLDDMPQRLAIIGSGFIGLEFASMFADFGTAVTVLQHNAEFLPREDADVAAAI
EECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHH
RAQLEAQGVKFLFNADTKAITPAADGGVRLSVAVKGMTRGASQACDSTPAGTGNAHTDIT
HHHHHHCCEEEEEECCCCEECCCCCCCEEEEEEEECCCCCHHHHCCCCCCCCCCCCCEEC
GATGTTDTATTTSPTSNPTDHATMSHVQTKPSDDGEPRFAEPAEARFCLTTDAVLVATGR
CCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECEEEEEECC
TPNVEGLHLEAAGVELTERGAVKVDELLRTTAADIWALGDVNGGPQHTYISLDDYRVVWS
CCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHEEEECCCCCCCCEEEEEECCHHHHHH
QLNGSARPYTVKDRKHVPSSTFLATPYSRVGLNEREAKAAGLDYVVKRLPVAAVPKAQVM
HCCCCCCCEEECCCCCCCCCCEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
RRPDGLMKAIVERNTGRILGAMLLSVESHEVINIVKLAMDLDAPASTLRDIVFTHPTIAE
HCCHHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHH
ALNDLFA
HHHHHCC
>Mature Secondary Structure 
STSTPNAISTPDTISTPSTSPTITTDALIIGFGKGGKTLAAKLSAAGRKVVVAEASANM
CCCCCCCCCCCCCCCCCCCCCCEEECEEEEEECCCCCHHHHHHHCCCCEEEEEECCCCC
YGGTCINIGCLPSKSLILSAEQARRDGANSTPETREAAFEAAIKEKRRVTSMLRDKNYHK
CCCEEEEEECCCCCCEEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LADQDNITVITGHAHFTGPHSVEIATAEGPVAVTASKIFINTGATPRIPDIPGIRTTPGV
CCCCCCEEEEECCCEECCCCEEEEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCC
YTSTGLMDLDDMPQRLAIIGSGFIGLEFASMFADFGTAVTVLQHNAEFLPREDADVAAAI
EECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHHHH
RAQLEAQGVKFLFNADTKAITPAADGGVRLSVAVKGMTRGASQACDSTPAGTGNAHTDIT
HHHHHHCCEEEEEECCCCEECCCCCCCEEEEEEEECCCCCHHHHCCCCCCCCCCCCCEEC
GATGTTDTATTTSPTSNPTDHATMSHVQTKPSDDGEPRFAEPAEARFCLTTDAVLVATGR
CCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECEEEEEECC
TPNVEGLHLEAAGVELTERGAVKVDELLRTTAADIWALGDVNGGPQHTYISLDDYRVVWS
CCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHEEEECCCCCCCCEEEEEECCHHHHHH
QLNGSARPYTVKDRKHVPSSTFLATPYSRVGLNEREAKAAGLDYVVKRLPVAAVPKAQVM
HCCCCCCCEEECCCCCCCCCCEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHH
RRPDGLMKAIVERNTGRILGAMLLSVESHEVINIVKLAMDLDAPASTLRDIVFTHPTIAE
HCCHHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHH
ALNDLFA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]