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The map label for this gene is dppB [H]

Identifier: 213692870

GI number: 213692870

Start: 2194810

End: 2195775

Strand: Reverse

Name: dppB [H]

Synonym: Blon_2011

Alternate gene names: 213692870

Gene position: 2195775-2194810 (Counterclockwise)

Preceding gene: 213692871

Following gene: 213692869

Centisome position: 77.51

GC content: 68.74

Gene sequence:

>966_bases
ATGCGGTTCTTGATGCAACGCTTGCTGCTGTTCGCGGCGGCGCTGTTCGGCATTTCGGTGCTGGTGTTCGCGATGCTGCG
CATCCTGCCGGGCGACGTGGCGGTCGTGATGGCCGGCATGAACGCATCGCCGGCGCGTGTGGCGGCCCTGCGCGCCGAAT
TCGGCCTTGACCGGCCGTATGTCGTGCAGTATCTCGACTGGGCCGGAGGGCTGCTGCACGGTGACCTCGGCGTGTCGGCG
CTGACCGGGCGGGCGGTGACCTCCCAGGTCGGCCAACGTGCGACGATCACGTTCCCGCTGATCGTGATGAGTCTGGCCAT
CGCGCTCACCCTCGGCTTGTCCATGGGCGCCGCCGCCGTGATCTCCCGGTCGCCGGCCGTGCGCGGTTTCCTGCGCGTGC
TGTCCATCGTGGGCGGCGCCGTACCGGCCCTGTGGAGCGGCCTGATGCTCATCCTTCTGTTCGCACGGGGCGTGGGCCTT
GTCGGTCTGCTGCCCTCGCAGGGGTTCCCCGCCGCTGGGTGGGGCGCTCCCGGGCGGGCGGTCTCGTCCCTGATCCTGCC
GGCGCTTGCCACCGGATTCGTGTCCGGTGCGGGCATCATGCGTTACACGCGCTCCATTCTGGAAGGCATCGCCGATGAGG
GAGGTCCGATCGATATGGCCATGTCCTGCGGCATGACCCGCACCCAGGCGTTGGTGCGCGTGGGATTGCGGTTGGCGGCT
CCGCAACTCGTCTCGGTGGTGGGGCTGGCGTTCGCCTCGATGATCACCGGCGTGATGGTGGTGGAGAACCTGTTCGCCCT
GCCCGGTCTGGGCGCCCTGCTGGTGGGCGACGTCGGCAACCGCGATCTGGTGGCCGTGCAAAGCGAGCTGTTCCTGCTCG
CCGCGTTCTTCCTGCTGATCGGCCTGGCGGTGGATCTGCTGCACGCGCTGCTTGACCCGCGTCTGGCCGCCGGAAAGGAG
GAATGA

Upstream 100 bases:

>100_bases
GCGCGGCGCGGGAGTGATTCCGTGGCGCGCCCGACCGTGGACGGCCCATCCGGCCGGTGACGCCACGGGCGGTGGCGAGG
GAATCGATAAGGGAGGCGTT

Downstream 100 bases:

>100_bases
TGGTTGATCGCAATGGTCGATGGCGTCGTTCGGGCGTGGTTCTGGGCACCATCTGGTCCCGTGGCACCGGCCGCTACTCG
CTGATCGTGCTGGGGTTGTG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MRFLMQRLLLFAAALFGISVLVFAMLRILPGDVAVVMAGMNASPARVAALRAEFGLDRPYVVQYLDWAGGLLHGDLGVSA
LTGRAVTSQVGQRATITFPLIVMSLAIALTLGLSMGAAAVISRSPAVRGFLRVLSIVGGAVPALWSGLMLILLFARGVGL
VGLLPSQGFPAAGWGAPGRAVSSLILPALATGFVSGAGIMRYTRSILEGIADEGGPIDMAMSCGMTRTQALVRVGLRLAA
PQLVSVVGLAFASMITGVMVVENLFALPGLGALLVGDVGNRDLVAVQSELFLLAAFFLLIGLAVDLLHALLDPRLAAGKE
E

Sequences:

>Translated_321_residues
MRFLMQRLLLFAAALFGISVLVFAMLRILPGDVAVVMAGMNASPARVAALRAEFGLDRPYVVQYLDWAGGLLHGDLGVSA
LTGRAVTSQVGQRATITFPLIVMSLAIALTLGLSMGAAAVISRSPAVRGFLRVLSIVGGAVPALWSGLMLILLFARGVGL
VGLLPSQGFPAAGWGAPGRAVSSLILPALATGFVSGAGIMRYTRSILEGIADEGGPIDMAMSCGMTRTQALVRVGLRLAA
PQLVSVVGLAFASMITGVMVVENLFALPGLGALLVGDVGNRDLVAVQSELFLLAAFFLLIGLAVDLLHALLDPRLAAGKE
E
>Mature_321_residues
MRFLMQRLLLFAAALFGISVLVFAMLRILPGDVAVVMAGMNASPARVAALRAEFGLDRPYVVQYLDWAGGLLHGDLGVSA
LTGRAVTSQVGQRATITFPLIVMSLAIALTLGLSMGAAAVISRSPAVRGFLRVLSIVGGAVPALWSGLMLILLFARGVGL
VGLLPSQGFPAAGWGAPGRAVSSLILPALATGFVSGAGIMRYTRSILEGIADEGGPIDMAMSCGMTRTQALVRVGLRLAA
PQLVSVVGLAFASMITGVMVVENLFALPGLGALLVGDVGNRDLVAVQSELFLLAAFFLLIGLAVDLLHALLDPRLAAGKE
E

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=340, Percent_Identity=33.2352941176471, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787053, Length=313, Percent_Identity=31.9488817891374, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1789888, Length=318, Percent_Identity=29.559748427673, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787497, Length=318, Percent_Identity=28.9308176100629, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787761, Length=340, Percent_Identity=30.8823529411765, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1787550, Length=269, Percent_Identity=24.907063197026, Blast_Score=98, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33158; Mature: 33158

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLMQRLLLFAAALFGISVLVFAMLRILPGDVAVVMAGMNASPARVAALRAEFGLDRPY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCHHHHHHHHHHHCCCCHH
VVQYLDWAGGLLHGDLGVSALTGRAVTSQVGQRATITFPLIVMSLAIALTLGLSMGAAAV
HHHHHHHHCCHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISRSPAVRGFLRVLSIVGGAVPALWSGLMLILLFARGVGLVGLLPSQGFPAAGWGAPGRA
HHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHH
VSSLILPALATGFVSGAGIMRYTRSILEGIADEGGPIDMAMSCGMTRTQALVRVGLRLAA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHH
PQLVSVVGLAFASMITGVMVVENLFALPGLGALLVGDVGNRDLVAVQSELFLLAAFFLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
GLAVDLLHALLDPRLAAGKEE
HHHHHHHHHHHCCHHCCCCCC
>Mature Secondary Structure
MRFLMQRLLLFAAALFGISVLVFAMLRILPGDVAVVMAGMNASPARVAALRAEFGLDRPY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECCCCCHHHHHHHHHHHCCCCHH
VVQYLDWAGGLLHGDLGVSALTGRAVTSQVGQRATITFPLIVMSLAIALTLGLSMGAAAV
HHHHHHHHCCHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ISRSPAVRGFLRVLSIVGGAVPALWSGLMLILLFARGVGLVGLLPSQGFPAAGWGAPGRA
HHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHH
VSSLILPALATGFVSGAGIMRYTRSILEGIADEGGPIDMAMSCGMTRTQALVRVGLRLAA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHH
PQLVSVVGLAFASMITGVMVVENLFALPGLGALLVGDVGNRDLVAVQSELFLLAAFFLLI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHH
GLAVDLLHALLDPRLAAGKEE
HHHHHHHHHHHCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]