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The map label for this gene is lip2 [H]

Identifier: 213692804

GI number: 213692804

Start: 2124250

End: 2125347

Strand: Direct

Name: lip2 [H]

Synonym: Blon_1942

Alternate gene names: 213692804

Gene position: 2124250-2125347 (Clockwise)

Preceding gene: 213692803

Following gene: 213692805

Centisome position: 74.99

GC content: 65.03

Gene sequence:

>1098_bases
ATGCCGATTAACGAAGCATTGCTCGCCGCGATGAAGGCCGCCACCCTCATCAAACCCAACGTGAGGAAAACCTATAGGAT
CCAACGCGCTGCCGAGGCGCTGGTCGCCAAGCAGACGCCGCCGAACCCGAAATGCCGCATCGAAGACGCCGCCGTCCCCA
TGCCGGACGGGCACGAGGTGCCGCTGCGCACGTTCACGCCGATCGCCCCGTATGGGACGGCCTTCCCCGGCGCCGATGCC
GTCGGTGCCATCGTTGCCGGCGCTTCGGCCGATGACGCCGGCAACATCACGCCACGGGGCACGATCCTGTTCGTCCACGG
CGGTGGCTGGTGCACCGGAGGCATCGACCTGTACGCGCAGGCGTGCGCCCATATGGCGGTTCGGCTGCAGCGTCGAGTGG
TCGCGGTCGAGTACCGTCTGTCCCCCGAGTACCGGTTCCCCGTGGCGGTCGAGGAATGTTATGAGGTGGCGCGGCGTCTA
TGCCGCGAACGGTCGTCGTCATCCGCGTCCGGCACCGACGGCATCACCTTGTTCGGCGACAGCGCCGGCGGCAATATCGT
GGCCGCCGTATCGCTCATGGCCCGCGACCGCGGCGAGTTCATGCCGCAGGCGCAGATGCTGCTGTATCCGGTGGTCGGCA
ACGACTACAATCCCGAGACCAGCCCATTCGAATCGGTGCGGACCAACGGCACCGACTACATCCTCACCGCACAGGACATG
GCCGACTACATCGACATGTACCGTTCGTCCGTGGCCGACCTGACCAATCCGTATTTCGCGCCGCTCACCGCGCATGACCT
GAGCAATCAGCCGCGCACGCTGGTGTTGTCCGCCGAATACTGCCCGCTCAGAGACGAGGACGAAGCGTACGCCCGTCGTC
TGCAATTGGTGAACGACAACGTCTCCTGTTACAGGATTCACGATGGCATCCACGGCTACCTACTCAACACGTCGGCCGTG
GGACTGGTGGCCACCACCTACCGAATCATCGAGCATTTCCTCGACGGCACACCGCTGGAACCGGCTCCCGGCACCGGCAC
CACCGCCAACGCACCGGAGGGAGGCGACGCGTGGCAAGACGTACTTGGTACCGACTAG

Upstream 100 bases:

>100_bases
CCGATGGACAGCCAGGGGGAGGAAGCCCGATCGGGTTTCCTCCCCCTGTCGTTGCCGAATCGTATGCACCGCGAACCCGA
CGTTGAAAGGACCTGCCGTC

Downstream 100 bases:

>100_bases
ACAACATCGGCAAGTTCTACTCCTCCCAGGCTGGCCGCTCCTCGCAGACCGTGTTCCGCTATTCGGCTGAGCTGGAGGAC
GACATCGCCCCGGACATCCT

Product: Alpha/beta hydrolase fold-3 domain protein

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 365; Mature: 364

Protein sequence:

>365_residues
MPINEALLAAMKAATLIKPNVRKTYRIQRAAEALVAKQTPPNPKCRIEDAAVPMPDGHEVPLRTFTPIAPYGTAFPGADA
VGAIVAGASADDAGNITPRGTILFVHGGGWCTGGIDLYAQACAHMAVRLQRRVVAVEYRLSPEYRFPVAVEECYEVARRL
CRERSSSSASGTDGITLFGDSAGGNIVAAVSLMARDRGEFMPQAQMLLYPVVGNDYNPETSPFESVRTNGTDYILTAQDM
ADYIDMYRSSVADLTNPYFAPLTAHDLSNQPRTLVLSAEYCPLRDEDEAYARRLQLVNDNVSCYRIHDGIHGYLLNTSAV
GLVATTYRIIEHFLDGTPLEPAPGTGTTANAPEGGDAWQDVLGTD

Sequences:

>Translated_365_residues
MPINEALLAAMKAATLIKPNVRKTYRIQRAAEALVAKQTPPNPKCRIEDAAVPMPDGHEVPLRTFTPIAPYGTAFPGADA
VGAIVAGASADDAGNITPRGTILFVHGGGWCTGGIDLYAQACAHMAVRLQRRVVAVEYRLSPEYRFPVAVEECYEVARRL
CRERSSSSASGTDGITLFGDSAGGNIVAAVSLMARDRGEFMPQAQMLLYPVVGNDYNPETSPFESVRTNGTDYILTAQDM
ADYIDMYRSSVADLTNPYFAPLTAHDLSNQPRTLVLSAEYCPLRDEDEAYARRLQLVNDNVSCYRIHDGIHGYLLNTSAV
GLVATTYRIIEHFLDGTPLEPAPGTGTTANAPEGGDAWQDVLGTD
>Mature_364_residues
PINEALLAAMKAATLIKPNVRKTYRIQRAAEALVAKQTPPNPKCRIEDAAVPMPDGHEVPLRTFTPIAPYGTAFPGADAV
GAIVAGASADDAGNITPRGTILFVHGGGWCTGGIDLYAQACAHMAVRLQRRVVAVEYRLSPEYRFPVAVEECYEVARRLC
RERSSSSASGTDGITLFGDSAGGNIVAAVSLMARDRGEFMPQAQMLLYPVVGNDYNPETSPFESVRTNGTDYILTAQDMA
DYIDMYRSSVADLTNPYFAPLTAHDLSNQPRTLVLSAEYCPLRDEDEAYARRLQLVNDNVSCYRIHDGIHGYLLNTSAVG
LVATTYRIIEHFLDGTPLEPAPGTGTTANAPEGGDAWQDVLGTD

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Homo sapiens, GI68299767, Length=301, Percent_Identity=25.9136212624585, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17540028, Length=279, Percent_Identity=26.1648745519713, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71996133, Length=279, Percent_Identity=26.1648745519713, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17567059, Length=160, Percent_Identity=28.125, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI72001146, Length=114, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094
- InterPro:   IPR002168 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 39404; Mature: 39273

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPINEALLAAMKAATLIKPNVRKTYRIQRAAEALVAKQTPPNPKCRIEDAAVPMPDGHEV
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCC
PLRTFTPIAPYGTAFPGADAVGAIVAGASADDAGNITPRGTILFVHGGGWCTGGIDLYAQ
CCCCCCCCCCCCCCCCCCHHHHHHEECCCCCCCCCCCCCCEEEEEECCCEEECCHHHHHH
ACAHMAVRLQRRVVAVEYRLSPEYRFPVAVEECYEVARRLCRERSSSSASGTDGITLFGD
HHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
SAGGNIVAAVSLMARDRGEFMPQAQMLLYPVVGNDYNPETSPFESVRTNGTDYILTAQDM
CCCCCEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHCCCCCEEEEHHHH
ADYIDMYRSSVADLTNPYFAPLTAHDLSNQPRTLVLSAEYCPLRDEDEAYARRLQLVNDN
HHHHHHHHHHHHHHCCCCCCCEEHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCC
VSCYRIHDGIHGYLLNTSAVGLVATTYRIIEHFLDGTPLEPAPGTGTTANAPEGGDAWQD
CEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
VLGTD
HHCCC
>Mature Secondary Structure 
PINEALLAAMKAATLIKPNVRKTYRIQRAAEALVAKQTPPNPKCRIEDAAVPMPDGHEV
CHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCC
PLRTFTPIAPYGTAFPGADAVGAIVAGASADDAGNITPRGTILFVHGGGWCTGGIDLYAQ
CCCCCCCCCCCCCCCCCCHHHHHHEECCCCCCCCCCCCCCEEEEEECCCEEECCHHHHHH
ACAHMAVRLQRRVVAVEYRLSPEYRFPVAVEECYEVARRLCRERSSSSASGTDGITLFGD
HHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEC
SAGGNIVAAVSLMARDRGEFMPQAQMLLYPVVGNDYNPETSPFESVRTNGTDYILTAQDM
CCCCCEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHCCCCCEEEEHHHH
ADYIDMYRSSVADLTNPYFAPLTAHDLSNQPRTLVLSAEYCPLRDEDEAYARRLQLVNDN
HHHHHHHHHHHHHHCCCCCCCEEHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCC
VSCYRIHDGIHGYLLNTSAVGLVATTYRIIEHFLDGTPLEPAPGTGTTANAPEGGDAWQD
CEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
VLGTD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1907455 [H]