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The map label for this gene is mepA [H]

Identifier: 213692765

GI number: 213692765

Start: 2070734

End: 2072092

Strand: Reverse

Name: mepA [H]

Synonym: Blon_1900

Alternate gene names: 213692765

Gene position: 2072092-2070734 (Counterclockwise)

Preceding gene: 213692766

Following gene: 213692764

Centisome position: 73.15

GC content: 61.22

Gene sequence:

>1359_bases
ATGGTGCAGATTCATGGCGTTAGACGCGCAAGCGCGGACGCGAAATATCGGCAGATGACCGGGCAGCCGGTCAAGCCGCT
GATTCTCAAACTGTGCTTGCCGGCCGTCATCTCCAACTTGGTGACCACCGCCTACAGTCTCACGGACACGTTCTTTATTG
GTCAGCTCGGCACCGCGCAGTCCGGTGCTATCGGCATCGCGTTCTCCGTCATGACCGTGATGCAGGCGCTCGGCTTCTTC
TTCGGCAACGGCGCGGGCAACTCGATGAGTCGCGAACTCGGCAAGCAAAACAATGATCGCGCCTCCCGACTACTGGCCGT
GGGCTTTGCGGGCGCGGTGATCTCCGGTTTGGTGATTGCCGCAATCGGGTTGCTGACCCTGCGGCCACTTGTCGTCATGC
TGGGCTCGACCTCGACGATTGCCCCATACGCCGTGCAATATCTGACGCCGTTGCTGGTCGCCGCACCCTGCGTGTGCGGT
TCGTTCGCACTCAACGGACTGCTGCGATACCAAGGGCAATCGACGTTCGGCATGATCGGGCTGGTTTCCGGCGCATTGCT
GAATTTCCTGCTTGCGCCATTGTTCATTTTCGTGGCCGGTCTGGGGATTTTCGGTGCCGGCCTCGCCACCGCCATCTGCC
AGACGGTGAGCTTTACGATTCTGACCACGATGAGCCGCAAATTCGGCGTGATGAAACTGTCCCTGCGCAATTGCAAGCCG
GATGTGCTGCTCATGCGCGAAGTGGCTGGCGGCGGCCTGCCTTCGCTGATCCGCCAAGGCGCCGGCTCGATTTCCGTGAC
TTGCGTGAACATCGCCGCCAACCCGTTCGGCGACGCGGCCATCGCCGGCATGGCCATCGTGATGCGCATCATGTTGGGCG
CCAATTCGGTGATCGTGGGTCTCGGCCAAGGCTTTCAGCCGGTGTGCGGCTACAACTACGGTGCCGGCCTGTTCGCGCGA
GTCAAAGAGGGATATTGGTTCTGCGTGCGGCTCACCACCTGCGTGCTCGTGGCGTTGGCAGCGCTGCTGTGGATTTTCGC
GCCGCAACTGGTCGAGATCTTCCGTTCCGACCCGGCCGTGGTGGCGGTGGGCGTGGCAGCGCTGCATATTCAATGCTGCA
CGGTGATTCTCAACGGCTTCAACATGATGGGCAATATGATGACCCAGACCATGGGCCGCACCGGCATCGCCTCGTTCCTG
GCCTTGTGCAGGCAAGGCCTGTTCCTGGCGCCAATCGTGCTGATTCTGCCGATGATGTTCGGCGTGCTCGGCGTGGAAAT
GGCCCAATCGGTGTCCGACGTGCTGACATTCGTGGTCACCATCCCGTTCATGCGGCGAATCCTGCACGAATTGCGGTAG

Upstream 100 bases:

>100_bases
CGCGGCCAATCCGAACAGCATCACCGGGCGGTATCTGTGCTGACTCGTATGGCGGTCACGCGCCTTCGCATAGGACCCTG
CGCGAGTAGGATAGCCGTCC

Downstream 100 bases:

>100_bases
ATGTCATCAAGATTTTCGACTTCCAGACCAGGTGGACCGAGCATATCTCGCTGAATCTCTGTAGTTTTTCCTTACCGTTG
CGTTCATTAGGTCGATTATG

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MVQIHGVRRASADAKYRQMTGQPVKPLILKLCLPAVISNLVTTAYSLTDTFFIGQLGTAQSGAIGIAFSVMTVMQALGFF
FGNGAGNSMSRELGKQNNDRASRLLAVGFAGAVISGLVIAAIGLLTLRPLVVMLGSTSTIAPYAVQYLTPLLVAAPCVCG
SFALNGLLRYQGQSTFGMIGLVSGALLNFLLAPLFIFVAGLGIFGAGLATAICQTVSFTILTTMSRKFGVMKLSLRNCKP
DVLLMREVAGGGLPSLIRQGAGSISVTCVNIAANPFGDAAIAGMAIVMRIMLGANSVIVGLGQGFQPVCGYNYGAGLFAR
VKEGYWFCVRLTTCVLVALAALLWIFAPQLVEIFRSDPAVVAVGVAALHIQCCTVILNGFNMMGNMMTQTMGRTGIASFL
ALCRQGLFLAPIVLILPMMFGVLGVEMAQSVSDVLTFVVTIPFMRRILHELR

Sequences:

>Translated_452_residues
MVQIHGVRRASADAKYRQMTGQPVKPLILKLCLPAVISNLVTTAYSLTDTFFIGQLGTAQSGAIGIAFSVMTVMQALGFF
FGNGAGNSMSRELGKQNNDRASRLLAVGFAGAVISGLVIAAIGLLTLRPLVVMLGSTSTIAPYAVQYLTPLLVAAPCVCG
SFALNGLLRYQGQSTFGMIGLVSGALLNFLLAPLFIFVAGLGIFGAGLATAICQTVSFTILTTMSRKFGVMKLSLRNCKP
DVLLMREVAGGGLPSLIRQGAGSISVTCVNIAANPFGDAAIAGMAIVMRIMLGANSVIVGLGQGFQPVCGYNYGAGLFAR
VKEGYWFCVRLTTCVLVALAALLWIFAPQLVEIFRSDPAVVAVGVAALHIQCCTVILNGFNMMGNMMTQTMGRTGIASFL
ALCRQGLFLAPIVLILPMMFGVLGVEMAQSVSDVLTFVVTIPFMRRILHELR
>Mature_452_residues
MVQIHGVRRASADAKYRQMTGQPVKPLILKLCLPAVISNLVTTAYSLTDTFFIGQLGTAQSGAIGIAFSVMTVMQALGFF
FGNGAGNSMSRELGKQNNDRASRLLAVGFAGAVISGLVIAAIGLLTLRPLVVMLGSTSTIAPYAVQYLTPLLVAAPCVCG
SFALNGLLRYQGQSTFGMIGLVSGALLNFLLAPLFIFVAGLGIFGAGLATAICQTVSFTILTTMSRKFGVMKLSLRNCKP
DVLLMREVAGGGLPSLIRQGAGSISVTCVNIAANPFGDAAIAGMAIVMRIMLGANSVIVGLGQGFQPVCGYNYGAGLFAR
VKEGYWFCVRLTTCVLVALAALLWIFAPQLVEIFRSDPAVVAVGVAALHIQCCTVILNGFNMMGNMMTQTMGRTGIASFL
ALCRQGLFLAPIVLILPMMFGVLGVEMAQSVSDVLTFVVTIPFMRRILHELR

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47647; Mature: 47647

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQIHGVRRASADAKYRQMTGQPVKPLILKLCLPAVISNLVTTAYSLTDTFFIGQLGTAQ
CEEECCCCHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGAIGIAFSVMTVMQALGFFFGNGAGNSMSRELGKQNNDRASRLLAVGFAGAVISGLVIA
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AIGLLTLRPLVVMLGSTSTIAPYAVQYLTPLLVAAPCVCGSFALNGLLRYQGQSTFGMIG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LVSGALLNFLLAPLFIFVAGLGIFGAGLATAICQTVSFTILTTMSRKFGVMKLSLRNCKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHCCCCC
DVLLMREVAGGGLPSLIRQGAGSISVTCVNIAANPFGDAAIAGMAIVMRIMLGANSVIVG
HHHHHHHHCCCCHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEE
LGQGFQPVCGYNYGAGLFARVKEGYWFCVRLTTCVLVALAALLWIFAPQLVEIFRSDPAV
CCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VAVGVAALHIQCCTVILNGFNMMGNMMTQTMGRTGIASFLALCRQGLFLAPIVLILPMMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GVLGVEMAQSVSDVLTFVVTIPFMRRILHELR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVQIHGVRRASADAKYRQMTGQPVKPLILKLCLPAVISNLVTTAYSLTDTFFIGQLGTAQ
CEEECCCCHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SGAIGIAFSVMTVMQALGFFFGNGAGNSMSRELGKQNNDRASRLLAVGFAGAVISGLVIA
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
AIGLLTLRPLVVMLGSTSTIAPYAVQYLTPLLVAAPCVCGSFALNGLLRYQGQSTFGMIG
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LVSGALLNFLLAPLFIFVAGLGIFGAGLATAICQTVSFTILTTMSRKFGVMKLSLRNCKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEHHCCCCC
DVLLMREVAGGGLPSLIRQGAGSISVTCVNIAANPFGDAAIAGMAIVMRIMLGANSVIVG
HHHHHHHHCCCCHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEE
LGQGFQPVCGYNYGAGLFARVKEGYWFCVRLTTCVLVALAALLWIFAPQLVEIFRSDPAV
CCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VAVGVAALHIQCCTVILNGFNMMGNMMTQTMGRTGIASFLALCRQGLFLAPIVLILPMMF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GVLGVEMAQSVSDVLTFVVTIPFMRRILHELR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA