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The map label for this gene is uvrA [H]

Identifier: 213692766

GI number: 213692766

Start: 2072150

End: 2074738

Strand: Reverse

Name: uvrA [H]

Synonym: Blon_1901

Alternate gene names: 213692766

Gene position: 2074738-2072150 (Counterclockwise)

Preceding gene: 213692767

Following gene: 213692765

Centisome position: 73.24

GC content: 64.27

Gene sequence:

>2589_bases
ATGACCAACAATCAACGGCCGCAGGCGATTGAGGTGCGCGGTGCGCGCGTGCATAACCTCAAGAACATCGACATTGACAT
TCCGCTGTGTGAACTGGTGGGCGTGGCCGGCGTCTCCGGTTCGGGCAAAAGCTCTCTGGCGCTCGGCGTGCTGTATGCGG
AAGGTTCGCGGCGCTACTTGGAAGCGCTGTCCACGTACACGCGCCGTCGACTGACCCAGGCCAGCCGCGCCCAGGTGGAC
GAAGTGCTGCACGTGCCGGCCGCGCTGGCTCTGCACCAGCGGCCCACGGTGCCCGGCATCCGCTCGACGTTCGGCACGAT
GACCGAATTGCTCAACAGCCTGCGACTCCTGTTCTCCCGCGTCGCCTCGCACGTGTGCTCGCATTGCGGGGCGCGCAACG
AGCCCACGCTGAACGTGGCGGCCGGACTGCCCATTACTTGCGTCAGCTGTGGCAAGGAATTCCATGCGCCCGGTGCTGAA
TCGCTCGCCTTCAACTCGGCCGGCGCCTGCCCGACCTGCTCCGGCAACGGCATCGTGCGCGAAGTAAACCGCGCGGCCCT
GGTCCCGGACGAGTCGAAACGCATCGACGACGGCGCTGTGCTGCCATGGGGCTCGCTCATGTGGGACCTCATGAAACAGG
TGTGCGGTGCGATGGGCGTGCGCACCAACGTGCCGTTCAGCGAGCTCACGCCCGAAGAACGCGACATCGTATTCAACGGG
CCAGCCGTCAAAAAGCACATCCTCTACAAGCCGAAGAAAGGCGACGATTTCGCCGAACTCGACTTCACCTACTTCAACGC
CGTGTACACGGTGGAGAATGCGCTCGCCAAAGCCAAGGACGAGAAGGGCCTGAAGCGTGTGGCCCGGTTCCTCAAGGAGG
GGCCGTGCGCCGACTGCAGTGGCACCCGACTGAGCGCCGTCGCCCGGGCTCCGCACGTGCGCGGGCTGAACTTGGCCGAA
GCCGGCGCGATGACCTTGGACGCGGCGGCGGATTGGGTGCGCGGAGTGCCGGAATCCCTGCGCCCCGACATGCGGCCGAT
GGCCACCAACATCTGCGAATCGTTCCTAGACGTGGCCCGACGACTGCTGGATCTGGGGCTCGGCTATCTGGCGCTTGATC
GCGCCGGCGCCACACTGTCGACCGGAGAACGCCAACGTGTGCAGCTCGCCCGGGCCGTGCGCAACCGCACCACCGGCGTG
CTGTATGTGCTCGACGAGCCATCCATCGGTCTGCATCCCTCGAACGTGGACGGGCTGCTCGGCGTGATGTATGACTTGGT
GGCGGACGGCAATTCCGTGGTGGTCGTGGACCATGACGTGCGTGTGCTCAAGGCGTGTGACCATCTCATTGAAATGGGGC
TGGTCGCCGGTGCCGAAGGTGGGCATGTGATCGTGCAAGGCACGGTCGGCGAGGTGGCGGCGAATCCCAGTAGTCGCATT
GCGCCGTTCCTATCTGATCAGGTGAGCGCGCGTATACGTGAGCGTGTGGCTGAATCACAGGTGTTCAGCCTTGGCCACAT
ACGCATGACAACCAGCCAGCTGCATACAGTCAAGCCGCTGGACGTTGATATCCCGCGCGGCCGGCTCGTGGCGGTGACCG
GCGTCTCCGGCTCAGGCAAGACCACGGTGGTGCTTGAATCGCTGATTCCCGCGCTCAAAGCGCAGGCAGCGGGGGAGCGG
TTGCCGGAACACGTGCTCGAGCTTAAAGCCGAGGGCATCAATCGCGCGAATCTCATCGACGCCACGCCGATTGGCGCAAA
TGTGCGTTCCACTGTGGCCACCTATGCCGATATTCACGACGAATTGCGCCGCGCCTTCGCCCGCGCGGACGACGCCAAAG
CGGGCGGCTGGAAGGCTGGCGATTTCTCGTACAACACCGGCAGACTGCGTTGCCCCACGTGCGACGGCACCGGTTCGATC
TCGCTCGATGTGCAGTTCCTGCCGGACGTGACCATCGAATGCCCGGATTGTGGAGGCTCCCGCTATGCGTCCGAAGCCGA
CGCGATTCGGCGTGCGGTTAAAGCGGCTAAGGGCAAAGCGGCGAAGATGAAGGTCCCGGATAAGCGCAAAGCTGCCAAGG
AAAAATTGAGTGAGGCGACGGGTCAGGGTGGCGGCAACATTTCCCTGAGCCTGCCTCAACTCATGGCAATGAGCGTGGAC
CAGGCGCTGGCCGTGACCAGCGACCTCAAGAAGGTTCACGCACGTCTGACCACCCTGCACGACTTGGGCCTCGGCTACTT
GACGCTCGGCGAACCGACTCCGGCGCTTTCGGGCGGCGAAGCCCAGCGGCTGAAACTCGCCAGCGAAATGGGCAAGGCCC
AATCGGACGCGGTATTCGTGTTCGATGAGCCGACCATCGGTCTGCACCCGTTCGACGTGCGCGTGCTGCTGGGCGTGTTC
GACCGGCTCGTGGCGAGCGGCGCAACAGTCGTGGTCATCGAACATGACCTTGACGTGATCGCCAATGCGGACTGGATCAT
CGACATGGGTCCGGGCGGCGGCGAAAGCGGCGGACGCATCGTCGCCACCGGAACGCCGGAACAAATCGCGGCCAATCCGA
ACAGCATCACCGGGCGGTATCTGTGCTGA

Upstream 100 bases:

>100_bases
GAAGCTCAGGCGGCGGCAGCCAAGGGCGAAGTCGAGAAAGAGGTGACGGCGTGACACTTGAACAGAGGTCAGATAGCGCG
GCGGCGGAGCAGTGCCGAGC

Downstream 100 bases:

>100_bases
CTCGTATGGCGGTCACGCGCCTTCGCATAGGACCCTGCGCGAGTAGGATAGCCGTCCATGGTGCAGATTCATGGCGTTAG
ACGCGCAAGCGCGGACGCGA

Product: ABC transporter

Products: NA

Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]

Number of amino acids: Translated: 862; Mature: 861

Protein sequence:

>862_residues
MTNNQRPQAIEVRGARVHNLKNIDIDIPLCELVGVAGVSGSGKSSLALGVLYAEGSRRYLEALSTYTRRRLTQASRAQVD
EVLHVPAALALHQRPTVPGIRSTFGTMTELLNSLRLLFSRVASHVCSHCGARNEPTLNVAAGLPITCVSCGKEFHAPGAE
SLAFNSAGACPTCSGNGIVREVNRAALVPDESKRIDDGAVLPWGSLMWDLMKQVCGAMGVRTNVPFSELTPEERDIVFNG
PAVKKHILYKPKKGDDFAELDFTYFNAVYTVENALAKAKDEKGLKRVARFLKEGPCADCSGTRLSAVARAPHVRGLNLAE
AGAMTLDAAADWVRGVPESLRPDMRPMATNICESFLDVARRLLDLGLGYLALDRAGATLSTGERQRVQLARAVRNRTTGV
LYVLDEPSIGLHPSNVDGLLGVMYDLVADGNSVVVVDHDVRVLKACDHLIEMGLVAGAEGGHVIVQGTVGEVAANPSSRI
APFLSDQVSARIRERVAESQVFSLGHIRMTTSQLHTVKPLDVDIPRGRLVAVTGVSGSGKTTVVLESLIPALKAQAAGER
LPEHVLELKAEGINRANLIDATPIGANVRSTVATYADIHDELRRAFARADDAKAGGWKAGDFSYNTGRLRCPTCDGTGSI
SLDVQFLPDVTIECPDCGGSRYASEADAIRRAVKAAKGKAAKMKVPDKRKAAKEKLSEATGQGGGNISLSLPQLMAMSVD
QALAVTSDLKKVHARLTTLHDLGLGYLTLGEPTPALSGGEAQRLKLASEMGKAQSDAVFVFDEPTIGLHPFDVRVLLGVF
DRLVASGATVVVIEHDLDVIANADWIIDMGPGGGESGGRIVATGTPEQIAANPNSITGRYLC

Sequences:

>Translated_862_residues
MTNNQRPQAIEVRGARVHNLKNIDIDIPLCELVGVAGVSGSGKSSLALGVLYAEGSRRYLEALSTYTRRRLTQASRAQVD
EVLHVPAALALHQRPTVPGIRSTFGTMTELLNSLRLLFSRVASHVCSHCGARNEPTLNVAAGLPITCVSCGKEFHAPGAE
SLAFNSAGACPTCSGNGIVREVNRAALVPDESKRIDDGAVLPWGSLMWDLMKQVCGAMGVRTNVPFSELTPEERDIVFNG
PAVKKHILYKPKKGDDFAELDFTYFNAVYTVENALAKAKDEKGLKRVARFLKEGPCADCSGTRLSAVARAPHVRGLNLAE
AGAMTLDAAADWVRGVPESLRPDMRPMATNICESFLDVARRLLDLGLGYLALDRAGATLSTGERQRVQLARAVRNRTTGV
LYVLDEPSIGLHPSNVDGLLGVMYDLVADGNSVVVVDHDVRVLKACDHLIEMGLVAGAEGGHVIVQGTVGEVAANPSSRI
APFLSDQVSARIRERVAESQVFSLGHIRMTTSQLHTVKPLDVDIPRGRLVAVTGVSGSGKTTVVLESLIPALKAQAAGER
LPEHVLELKAEGINRANLIDATPIGANVRSTVATYADIHDELRRAFARADDAKAGGWKAGDFSYNTGRLRCPTCDGTGSI
SLDVQFLPDVTIECPDCGGSRYASEADAIRRAVKAAKGKAAKMKVPDKRKAAKEKLSEATGQGGGNISLSLPQLMAMSVD
QALAVTSDLKKVHARLTTLHDLGLGYLTLGEPTPALSGGEAQRLKLASEMGKAQSDAVFVFDEPTIGLHPFDVRVLLGVF
DRLVASGATVVVIEHDLDVIANADWIIDMGPGGGESGGRIVATGTPEQIAANPNSITGRYLC
>Mature_861_residues
TNNQRPQAIEVRGARVHNLKNIDIDIPLCELVGVAGVSGSGKSSLALGVLYAEGSRRYLEALSTYTRRRLTQASRAQVDE
VLHVPAALALHQRPTVPGIRSTFGTMTELLNSLRLLFSRVASHVCSHCGARNEPTLNVAAGLPITCVSCGKEFHAPGAES
LAFNSAGACPTCSGNGIVREVNRAALVPDESKRIDDGAVLPWGSLMWDLMKQVCGAMGVRTNVPFSELTPEERDIVFNGP
AVKKHILYKPKKGDDFAELDFTYFNAVYTVENALAKAKDEKGLKRVARFLKEGPCADCSGTRLSAVARAPHVRGLNLAEA
GAMTLDAAADWVRGVPESLRPDMRPMATNICESFLDVARRLLDLGLGYLALDRAGATLSTGERQRVQLARAVRNRTTGVL
YVLDEPSIGLHPSNVDGLLGVMYDLVADGNSVVVVDHDVRVLKACDHLIEMGLVAGAEGGHVIVQGTVGEVAANPSSRIA
PFLSDQVSARIRERVAESQVFSLGHIRMTTSQLHTVKPLDVDIPRGRLVAVTGVSGSGKTTVVLESLIPALKAQAAGERL
PEHVLELKAEGINRANLIDATPIGANVRSTVATYADIHDELRRAFARADDAKAGGWKAGDFSYNTGRLRCPTCDGTGSIS
LDVQFLPDVTIECPDCGGSRYASEADAIRRAVKAAKGKAAKMKVPDKRKAAKEKLSEATGQGGGNISLSLPQLMAMSVDQ
ALAVTSDLKKVHARLTTLHDLGLGYLTLGEPTPALSGGEAQRLKLASEMGKAQSDAVFVFDEPTIGLHPFDVRVLLGVFD
RLVASGATVVVIEHDLDVIANADWIIDMGPGGGESGGRIVATGTPEQIAANPNSITGRYLC

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h

COG id: COG0178

COG function: function code L; Excinuclease ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Escherichia coli, GI2367343, Length=726, Percent_Identity=31.5426997245179, Blast_Score=351, Evalue=1e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR013815
- InterPro:   IPR003593
- InterPro:   IPR004602 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 91651; Mature: 91520

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNNQRPQAIEVRGARVHNLKNIDIDIPLCELVGVAGVSGSGKSSLALGVLYAEGSRRYL
CCCCCCCCEEEECCCEECCCCCCEECCCHHHHHHCCCCCCCCCCCEEEEEEEECCCHHHH
EALSTYTRRRLTQASRAQVDEVLHVPAALALHQRPTVPGIRSTFGTMTELLNSLRLLFSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VASHVCSHCGARNEPTLNVAAGLPITCVSCGKEFHAPGAESLAFNSAGACPTCSGNGIVR
HHHHHHHHCCCCCCCCEEEECCCCEEEECCCHHHCCCCCCCEECCCCCCCCCCCCCCHHH
EVNRAALVPDESKRIDDGAVLPWGSLMWDLMKQVCGAMGVRTNVPFSELTPEERDIVFNG
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEECC
PAVKKHILYKPKKGDDFAELDFTYFNAVYTVENALAKAKDEKGLKRVARFLKEGPCADCS
CCHHHHHEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTRLSAVARAPHVRGLNLAEAGAMTLDAAADWVRGVPESLRPDMRPMATNICESFLDVAR
CCHHHHHHCCCCCCCCCHHHCCCEEHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHH
RLLDLGLGYLALDRAGATLSTGERQRVQLARAVRNRTTGVLYVLDEPSIGLHPSNVDGLL
HHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHH
GVMYDLVADGNSVVVVDHDVRVLKACDHLIEMGLVAGAEGGHVIVQGTVGEVAANPSSRI
HHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCCCCHHC
APFLSDQVSARIRERVAESQVFSLGHIRMTTSQLHTVKPLDVDIPRGRLVAVTGVSGSGK
CHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCEECCCCCCCCCCCEEEEEECCCCCC
TTVVLESLIPALKAQAAGERLPEHVLELKAEGINRANLIDATPIGANVRSTVATYADIHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHH
ELRRAFARADDAKAGGWKAGDFSYNTGRLRCPTCDGTGSISLDVQFLPDVTIECPDCGGS
HHHHHHHCCCCCCCCCEECCCCCCCCCEEECCCCCCCCCEEEEEEECCCCEEECCCCCCC
RYASEADAIRRAVKAAKGKAAKMKVPDKRKAAKEKLSEATGQGGGNISLSLPQLMAMSVD
CCCHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHH
QALAVTSDLKKVHARLTTLHDLGLGYLTLGEPTPALSGGEAQRLKLASEMGKAQSDAVFV
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEE
FDEPTIGLHPFDVRVLLGVFDRLVASGATVVVIEHDLDVIANADWIIDMGPGGGESGGRI
ECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCEEEECCCCCCCCCCEE
VATGTPEQIAANPNSITGRYLC
EECCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TNNQRPQAIEVRGARVHNLKNIDIDIPLCELVGVAGVSGSGKSSLALGVLYAEGSRRYL
CCCCCCCEEEECCCEECCCCCCEECCCHHHHHHCCCCCCCCCCCEEEEEEEECCCHHHH
EALSTYTRRRLTQASRAQVDEVLHVPAALALHQRPTVPGIRSTFGTMTELLNSLRLLFSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VASHVCSHCGARNEPTLNVAAGLPITCVSCGKEFHAPGAESLAFNSAGACPTCSGNGIVR
HHHHHHHHCCCCCCCCEEEECCCCEEEECCCHHHCCCCCCCEECCCCCCCCCCCCCCHHH
EVNRAALVPDESKRIDDGAVLPWGSLMWDLMKQVCGAMGVRTNVPFSELTPEERDIVFNG
HCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCEEECC
PAVKKHILYKPKKGDDFAELDFTYFNAVYTVENALAKAKDEKGLKRVARFLKEGPCADCS
CCHHHHHEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GTRLSAVARAPHVRGLNLAEAGAMTLDAAADWVRGVPESLRPDMRPMATNICESFLDVAR
CCHHHHHHCCCCCCCCCHHHCCCEEHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHH
RLLDLGLGYLALDRAGATLSTGERQRVQLARAVRNRTTGVLYVLDEPSIGLHPSNVDGLL
HHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHH
GVMYDLVADGNSVVVVDHDVRVLKACDHLIEMGLVAGAEGGHVIVQGTVGEVAANPSSRI
HHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHCCCCCHHC
APFLSDQVSARIRERVAESQVFSLGHIRMTTSQLHTVKPLDVDIPRGRLVAVTGVSGSGK
CHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHCEECCCCCCCCCCCEEEEEECCCCCC
TTVVLESLIPALKAQAAGERLPEHVLELKAEGINRANLIDATPIGANVRSTVATYADIHD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHH
ELRRAFARADDAKAGGWKAGDFSYNTGRLRCPTCDGTGSISLDVQFLPDVTIECPDCGGS
HHHHHHHCCCCCCCCCEECCCCCCCCCEEECCCCCCCCCEEEEEEECCCCEEECCCCCCC
RYASEADAIRRAVKAAKGKAAKMKVPDKRKAAKEKLSEATGQGGGNISLSLPQLMAMSVD
CCCHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHH
QALAVTSDLKKVHARLTTLHDLGLGYLTLGEPTPALSGGEAQRLKLASEMGKAQSDAVFV
HHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEE
FDEPTIGLHPFDVRVLLGVFDRLVASGATVVVIEHDLDVIANADWIIDMGPGGGESGGRI
ECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCEEEECCCCCCCCCCEE
VATGTPEQIAANPNSITGRYLC
EECCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]