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The map label for this gene is lacA [H]

Identifier: 213692761

GI number: 213692761

Start: 2068422

End: 2068751

Strand: Reverse

Name: lacA [H]

Synonym: Blon_1896

Alternate gene names: 213692761

Gene position: 2068751-2068422 (Counterclockwise)

Preceding gene: 213692762

Following gene: 213692760

Centisome position: 73.03

GC content: 63.64

Gene sequence:

>330_bases
ATGAAGGCGTTCTTCGGCGCTGCGGGGGAGGGCCTGTACCTCGAAGGCCCGGTGTACGCGAACTGGGGCAGCAATACGTA
CTGGGGCGAGCGCTGCTACGCCAACTTCAACCTGACGCTGGTCGACGATGGCGATATCTTCATCGGCTCCCACACCATGC
TCGGCCCCAACGTCACGCTTGTAGCCACCGGCCATCCTGTGCGTCCGGACCTGCGCTACCGGGGCGCCCAGTATTCGTGT
CCGATCCACATCGGCGAAAACGTGTGGATCGACACGTTCGCGCCGACCCACACGTTGCGCCCGAGGGCCACCGGAATGCA
ATACACGTAG

Upstream 100 bases:

>100_bases
ACGATGTGGATGGCTTCTTCGACCTGCAGGCCGCCCAGCGCACCTCCAGCTCGAACTCAACGCCACGCCGCTGACCCACC
CGAAGCGCCGTACCGAACTC

Downstream 100 bases:

>100_bases
CGGTGCTCGCGCAGCACCGGCAACACGGGGTGGCAGGCGGCTCATTAGCACGGGGAACGGTTGAACGAGAAGTGGATTGG
CATGTGGTGGTATCGAACAT

Product: galactoside O-acetyltransferase

Products: NA

Alternate protein names: GAT; Thiogalactoside acetyltransferase [H]

Number of amino acids: Translated: 109; Mature: 109

Protein sequence:

>109_residues
MKAFFGAAGEGLYLEGPVYANWGSNTYWGERCYANFNLTLVDDGDIFIGSHTMLGPNVTLVATGHPVRPDLRYRGAQYSC
PIHIGENVWIDTFAPTHTLRPRATGMQYT

Sequences:

>Translated_109_residues
MKAFFGAAGEGLYLEGPVYANWGSNTYWGERCYANFNLTLVDDGDIFIGSHTMLGPNVTLVATGHPVRPDLRYRGAQYSC
PIHIGENVWIDTFAPTHTLRPRATGMQYT
>Mature_109_residues
MKAFFGAAGEGLYLEGPVYANWGSNTYWGERCYANFNLTLVDDGDIFIGSHTMLGPNVTLVATGHPVRPDLRYRGAQYSC
PIHIGENVWIDTFAPTHTLRPRATGMQYT

Specific function: May Assist Cellular Detoxification By Acetylating Nonmetabolizable Pyranosides, Thereby Preventing Their Reentry Into The Cell. [C]

COG id: COG0110

COG function: function code R; Acetyltransferase (isoleucine patch superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1786537, Length=90, Percent_Identity=52.2222222222222, Blast_Score=99, Evalue=5e-23,
Organism=Escherichia coli, GI1786664, Length=90, Percent_Identity=35.5555555555556, Blast_Score=62, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6322243, Length=90, Percent_Identity=36.6666666666667, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00132 Hexapep [H]

EC number: =2.3.1.18 [H]

Molecular weight: Translated: 12101; Mature: 12101

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFFGAAGEGLYLEGPVYANWGSNTYWGERCYANFNLTLVDDGDIFIGSHTMLGPNVTL
CCCCCCCCCCCEEEECCEEEECCCCCCCCCEEEECCEEEEEECCCEEECCCEEECCCEEE
VATGHPVRPDLRYRGAQYSCPIHIGENVWIDTFAPTHTLRPRATGMQYT
EECCCCCCCCCEECCCCEECCEEECCCEEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKAFFGAAGEGLYLEGPVYANWGSNTYWGERCYANFNLTLVDDGDIFIGSHTMLGPNVTL
CCCCCCCCCCCEEEECCEEEECCCCCCCCCEEEECCEEEEEECCCEEECCCEEECCCEEE
VATGHPVRPDLRYRGAQYSCPIHIGENVWIDTFAPTHTLRPRATGMQYT
EECCCCCCCCCEECCCCEECCEEECCCEEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]