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The map label for this gene is moeZ [H]

Identifier: 213692737

GI number: 213692737

Start: 2040136

End: 2040945

Strand: Reverse

Name: moeZ [H]

Synonym: Blon_1871

Alternate gene names: 213692737

Gene position: 2040945-2040136 (Counterclockwise)

Preceding gene: 213692738

Following gene: 213692736

Centisome position: 72.05

GC content: 62.22

Gene sequence:

>810_bases
ATGGCATTGACTGATGAACAGGTGGAGCGGTACGCGCGCCATCTGATTTTGAAGGGGCTGGGCGTCAAAGGGCAGAAGCG
GTTGTTGGCCTCCAGCGTGCTCATCATTGGAGCGGGCGGGCTTGGCTCTCCGGCCGCCCTGTATCTGGCGGCGGCCGGCG
TTGGCCATATCGGACTGGTGGACGGCGATGTGGTGGATATGAGCAATCTGCAACGTCAGATCATCCATACCACCGCACGT
GTCGGAGCGCCCAAAGTGGAATCCGCGGCCACGGCCATCCGCGCGCTCAACCCAGATGTGACGGTCGACACCTACTACGA
GCTCGTCGATGCCAGCAACATCGCCGGCCTCATCGAACCGTACGATCTGGTGATCGATGCCACCGACAACTTCGCCGCAA
AATTCCTCATCAATGACGCATGTGTGCTGGCCGGCAAGCCGTATATCCATGCGGGCGTGGTCGGGTTCTCCGGCCAGGTG
ATGACCGTCATCCCAGGCGAAGGCCCCTGCTACCGCTGCATCTTCCGCGACATGCCCACCGCCGGTGAGATTCCGACCTG
CAAGGAAGCCGGCGTGCTGGGCGCGGTGGTCGGTGTGATCGGCAGTCTGGAAGCCACCGAAGCCGTGAAGTTGATTGCCG
GCGTGGGGGAGCCGTTGGTGGGGCGCATGCTCACCGTGGATGCCCTGACCATGAACATCCGCCGTGTGCCGTTGCCGAAC
CATGTGCCCGACTGCCCGGTGTGCGGTGAGCAGCCGACCATTACTGCTATTGATCCGGCCAACTATATTCAGCCGGCTTG
CGCGATTTAG

Upstream 100 bases:

>100_bases
CCGACTACGGGATATTTGCACTGACACTTTTATTAGCTCCCCTCTCTGAGGGGAGCTGGCCGCGTAGCGGACTGAGGGGA
GCTGGAAACATGGAGAAAAC

Downstream 100 bases:

>100_bases
AGCTATGTGGCACCCCTCCTTGAGGGGAGCCAAGATCGGAACGAGAGGGGAAGAACATGCCTATTGCTTTGCGTAATGCG
GTCGATGACGATGAGAGCAG

Product: thiazole biosynthesis adenylyltransferase ThiF

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MALTDEQVERYARHLILKGLGVKGQKRLLASSVLIIGAGGLGSPAALYLAAAGVGHIGLVDGDVVDMSNLQRQIIHTTAR
VGAPKVESAATAIRALNPDVTVDTYYELVDASNIAGLIEPYDLVIDATDNFAAKFLINDACVLAGKPYIHAGVVGFSGQV
MTVIPGEGPCYRCIFRDMPTAGEIPTCKEAGVLGAVVGVIGSLEATEAVKLIAGVGEPLVGRMLTVDALTMNIRRVPLPN
HVPDCPVCGEQPTITAIDPANYIQPACAI

Sequences:

>Translated_269_residues
MALTDEQVERYARHLILKGLGVKGQKRLLASSVLIIGAGGLGSPAALYLAAAGVGHIGLVDGDVVDMSNLQRQIIHTTAR
VGAPKVESAATAIRALNPDVTVDTYYELVDASNIAGLIEPYDLVIDATDNFAAKFLINDACVLAGKPYIHAGVVGFSGQV
MTVIPGEGPCYRCIFRDMPTAGEIPTCKEAGVLGAVVGVIGSLEATEAVKLIAGVGEPLVGRMLTVDALTMNIRRVPLPN
HVPDCPVCGEQPTITAIDPANYIQPACAI
>Mature_268_residues
ALTDEQVERYARHLILKGLGVKGQKRLLASSVLIIGAGGLGSPAALYLAAAGVGHIGLVDGDVVDMSNLQRQIIHTTARV
GAPKVESAATAIRALNPDVTVDTYYELVDASNIAGLIEPYDLVIDATDNFAAKFLINDACVLAGKPYIHAGVVGFSGQVM
TVIPGEGPCYRCIFRDMPTAGEIPTCKEAGVLGAVVGVIGSLEATEAVKLIAGVGEPLVGRMLTVDALTMNIRRVPLPNH
VPDCPVCGEQPTITAIDPANYIQPACAI

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=254, Percent_Identity=46.8503937007874, Blast_Score=205, Evalue=3e-53,
Organism=Homo sapiens, GI4885649, Length=156, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI13376212, Length=178, Percent_Identity=34.2696629213483, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI38327032, Length=174, Percent_Identity=33.9080459770115, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI38045942, Length=168, Percent_Identity=27.9761904761905, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI38045944, Length=180, Percent_Identity=27.7777777777778, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI23510338, Length=172, Percent_Identity=29.6511627906977, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI23510340, Length=172, Percent_Identity=29.6511627906977, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI38045948, Length=168, Percent_Identity=32.1428571428571, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787048, Length=250, Percent_Identity=44, Blast_Score=208, Evalue=4e-55,
Organism=Escherichia coli, GI87082356, Length=248, Percent_Identity=41.9354838709677, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1789177, Length=159, Percent_Identity=32.0754716981132, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17540406, Length=255, Percent_Identity=42.3529411764706, Blast_Score=210, Evalue=6e-55,
Organism=Caenorhabditis elegans, GI193203301, Length=153, Percent_Identity=29.4117647058824, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17508819, Length=178, Percent_Identity=29.2134831460674, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6321903, Length=261, Percent_Identity=37.9310344827586, Blast_Score=176, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6320598, Length=169, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322639, Length=189, Percent_Identity=30.6878306878307, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6325323, Length=170, Percent_Identity=27.0588235294118, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24582879, Length=255, Percent_Identity=44.3137254901961, Blast_Score=227, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24660640, Length=164, Percent_Identity=32.9268292682927, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24641311, Length=257, Percent_Identity=29.9610894941634, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI20129973, Length=169, Percent_Identity=30.1775147928994, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28573937, Length=176, Percent_Identity=30.1136363636364, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 28008; Mature: 27877

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALTDEQVERYARHLILKGLGVKGQKRLLASSVLIIGAGGLGSPAALYLAAAGVGHIGLV
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCEEEEEECCCCCCHHHHHHHHCCCCEEEEC
DGDVVDMSNLQRQIIHTTARVGAPKVESAATAIRALNPDVTVDTYYELVDASNIAGLIEP
CCCEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCC
YDLVIDATDNFAAKFLINDACVLAGKPYIHAGVVGFSGQVMTVIPGEGPCYRCIFRDMPT
EEEEEECCCCCEEEEEECCEEEECCCCEEEEEEEECCCEEEEEECCCCCEEEHHHHCCCC
AGEIPTCKEAGVLGAVVGVIGSLEATEAVKLIAGVGEPLVGRMLTVDALTMNIRRVPLPN
CCCCCCCHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHEEEEEHEEEEEEECCCCC
HVPDCPVCGEQPTITAIDPANYIQPACAI
CCCCCCCCCCCCCEEEECCHHHCCCCCCC
>Mature Secondary Structure 
ALTDEQVERYARHLILKGLGVKGQKRLLASSVLIIGAGGLGSPAALYLAAAGVGHIGLV
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHCEEEEEECCCCCCHHHHHHHHCCCCEEEEC
DGDVVDMSNLQRQIIHTTARVGAPKVESAATAIRALNPDVTVDTYYELVDASNIAGLIEP
CCCEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCC
YDLVIDATDNFAAKFLINDACVLAGKPYIHAGVVGFSGQVMTVIPGEGPCYRCIFRDMPT
EEEEEECCCCCEEEEEECCEEEECCCCEEEEEEEECCCEEEEEECCCCCEEEHHHHCCCC
AGEIPTCKEAGVLGAVVGVIGSLEATEAVKLIAGVGEPLVGRMLTVDALTMNIRRVPLPN
CCCCCCCHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHEEEEEHEEEEEEECCCCC
HVPDCPVCGEQPTITAIDPANYIQPACAI
CCCCCCCCCCCCCEEEECCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]