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The map label for this gene is frdB [H]

Identifier: 213692570

GI number: 213692570

Start: 1862996

End: 1863961

Strand: Direct

Name: frdB [H]

Synonym: Blon_1702

Alternate gene names: 213692570

Gene position: 1862996-1863961 (Clockwise)

Preceding gene: 213692569

Following gene: 213692571

Centisome position: 65.77

GC content: 66.67

Gene sequence:

>966_bases
ATGGCTGAGGCGAGCAACACGACGGTTACCCTGCAAGTGCATCGTTTCACGCCGCGACCCGAGCGCGCCGAACGTGCACG
CGGCGGCAGCCCGTTCGCCAAGAAAAACTCCCCGTTCGGCGGCGGCTCGGATTCGGCGGCACGCCGTCGTCCGCGCGGCA
AGCAGTGGGTGCAGGAATACACGATTCCCGCGCGCCCCTCGGACACCGTGCTCGACTGCCTGCTGACCATCAAACGCACC
GTCGACCCGACGCTGGCCTTCCGCTATTCGTGCGGTCACGGCATGTGCGGTTCGGACGCCGTGGCCATCAACGGCACCCC
CACCCTGCTGTGCACGGCCACCATCCGCGATTGGGCCAAGCAGCCCGGCGCCATCCCCGAAGTCGATGACGAAGGGTTCC
GGCACACCGGCACCGAGTCCGAAGAATCCGACGATTCCGCGGAAAACGACGCAAACGCGGCAGCCGACCAGGACTCGGCC
GCAAACGGCTCGCTGGGAGTCATCGAACTGGCATCCCTGCCCGGCTTCCCGCCGCAGCGCGACCTCATCGCCGACATCGA
CCCGATGCTCAACCAAATAAGGAAGCTCACCCCATATCTTCAGGCGGACGGCGTGCTCGCCACCACCGCCGAAGGCAAGG
TGGACGTGTTCGAATACCTGCAGAACCCCGAACAACTCGCCAAATACGAGCTGCTGAGCAACTGCATCGCCTGCGGCGTG
TGCGAAGGCGCCTGCCCGGTGTACGCCGGCGGCGACGCTTTCATCGGCCCGGCCGCGCTGATTTGGGCCTCCCGTTTCGT
CAACGATTCTCGCGACACCAAGGCCATGGAGCGTATGGACGCCATCGACACCGCCGACGGCGTGGCCGCCTGCCAGTCCG
TGCGCGCCTGCTCCCGCCACTGCCCGCGCGGCATCGATGTGGGCGAGGAGATGTGGCAGATCGTGGCCAAGGTCCGCGAG
CGCTAA

Upstream 100 bases:

>100_bases
ACTGATCCGCTGGTGGTAATACCAAGCCGCCTAGGGCTTGTGGCACAATAGGTTGGCTGATTATTGGACTTGACATCCCA
CTGTTTCATGGAGGCAGAAC

Downstream 100 bases:

>100_bases
GCCGCGCCGCGGCTGGCTGCGGCGATCGTCTAAGCACATGCGTCGATGCATCCGCCGGGTGCCCGCACGAGAGAAGACAT
GAAGGAACGAATTATGGACA

Product: succinate dehydrogenase and fumarate reductase iron-sulfur protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MAEASNTTVTLQVHRFTPRPERAERARGGSPFAKKNSPFGGGSDSAARRRPRGKQWVQEYTIPARPSDTVLDCLLTIKRT
VDPTLAFRYSCGHGMCGSDAVAINGTPTLLCTATIRDWAKQPGAIPEVDDEGFRHTGTESEESDDSAENDANAAADQDSA
ANGSLGVIELASLPGFPPQRDLIADIDPMLNQIRKLTPYLQADGVLATTAEGKVDVFEYLQNPEQLAKYELLSNCIACGV
CEGACPVYAGGDAFIGPAALIWASRFVNDSRDTKAMERMDAIDTADGVAACQSVRACSRHCPRGIDVGEEMWQIVAKVRE
R

Sequences:

>Translated_321_residues
MAEASNTTVTLQVHRFTPRPERAERARGGSPFAKKNSPFGGGSDSAARRRPRGKQWVQEYTIPARPSDTVLDCLLTIKRT
VDPTLAFRYSCGHGMCGSDAVAINGTPTLLCTATIRDWAKQPGAIPEVDDEGFRHTGTESEESDDSAENDANAAADQDSA
ANGSLGVIELASLPGFPPQRDLIADIDPMLNQIRKLTPYLQADGVLATTAEGKVDVFEYLQNPEQLAKYELLSNCIACGV
CEGACPVYAGGDAFIGPAALIWASRFVNDSRDTKAMERMDAIDTADGVAACQSVRACSRHCPRGIDVGEEMWQIVAKVRE
R
>Mature_320_residues
AEASNTTVTLQVHRFTPRPERAERARGGSPFAKKNSPFGGGSDSAARRRPRGKQWVQEYTIPARPSDTVLDCLLTIKRTV
DPTLAFRYSCGHGMCGSDAVAINGTPTLLCTATIRDWAKQPGAIPEVDDEGFRHTGTESEESDDSAENDANAAADQDSAA
NGSLGVIELASLPGFPPQRDLIADIDPMLNQIRKLTPYLQADGVLATTAEGKVDVFEYLQNPEQLAKYELLSNCIACGVC
EGACPVYAGGDAFIGPAALIWASRFVNDSRDTKAMERMDAIDTADGVAACQSVRACSRHCPRGIDVGEEMWQIVAKVRER

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=256, Percent_Identity=30.859375, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI1790596, Length=247, Percent_Identity=28.7449392712551, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1786943, Length=268, Percent_Identity=31.3432835820896, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17533915, Length=266, Percent_Identity=27.4436090225564, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322987, Length=266, Percent_Identity=27.8195488721804, Blast_Score=99, Evalue=6e-22,
Organism=Drosophila melanogaster, GI17137106, Length=316, Percent_Identity=28.7974683544304, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24643156, Length=246, Percent_Identity=28.4552845528455, Blast_Score=109, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 34566; Mature: 34435

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEASNTTVTLQVHRFTPRPERAERARGGSPFAKKNSPFGGGSDSAARRRPRGKQWVQEY
CCCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHC
TIPARPSDTVLDCLLTIKRTVDPTLAFRYSCGHGMCGSDAVAINGTPTLLCTATIRDWAK
CCCCCCCHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCEEEECCCCCEEEEHHHHHHHH
QPGAIPEVDDEGFRHTGTESEESDDSAENDANAAADQDSAANGSLGVIELASLPGFPPQR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCH
DLIADIDPMLNQIRKLTPYLQADGVLATTAEGKVDVFEYLQNPEQLAKYELLSNCIACGV
HHHHHHHHHHHHHHHHCCHHHCCCEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHC
CEGACPVYAGGDAFIGPAALIWASRFVNDSRDTKAMERMDAIDTADGVAACQSVRACSRH
CCCCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CPRGIDVGEEMWQIVAKVRER
CCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEASNTTVTLQVHRFTPRPERAERARGGSPFAKKNSPFGGGSDSAARRRPRGKQWVQEY
CCCCCCEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHC
TIPARPSDTVLDCLLTIKRTVDPTLAFRYSCGHGMCGSDAVAINGTPTLLCTATIRDWAK
CCCCCCCHHHHHHHHHHHHHCCCHHEEEECCCCCCCCCCEEEECCCCCEEEEHHHHHHHH
QPGAIPEVDDEGFRHTGTESEESDDSAENDANAAADQDSAANGSLGVIELASLPGFPPQR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCH
DLIADIDPMLNQIRKLTPYLQADGVLATTAEGKVDVFEYLQNPEQLAKYELLSNCIACGV
HHHHHHHHHHHHHHHHCCHHHCCCEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHC
CEGACPVYAGGDAFIGPAALIWASRFVNDSRDTKAMERMDAIDTADGVAACQSVRACSRH
CCCCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CPRGIDVGEEMWQIVAKVRER
CCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]