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The map label for this gene is pip [H]

Identifier: 213692559

GI number: 213692559

Start: 1845065

End: 1846543

Strand: Reverse

Name: pip [H]

Synonym: Blon_1691

Alternate gene names: 213692559

Gene position: 1846543-1845065 (Counterclockwise)

Preceding gene: 213692562

Following gene: 213692558

Centisome position: 65.19

GC content: 63.42

Gene sequence:

>1479_bases
ATGACAATGCTGAGCAAATACCACGTGCCCGGACTGGCCATAGAGGACCATTCCATCGATGTTCCGCTCGACTGGACCGG
CCACGAGCCCGGACGGGCATTCGACGGGGAAACCATCAAACTGTTCTATCGCGTGGTCACCGCGCCCGAACACGTGCATG
ACGACCTGCCCCTGCTGATCTTCCTGCAAGGCGGTCCCGGCGGTGCCGGCCCGCGCCTCAACAGCCCGACCTCCGACGGA
TGGATCGAGGAGGCCATCAGGCACTTCCGGGTGATCCTGCCCGACCAGCGCGGCACCGGCCGCTCCTCGCGCGTGGACAC
GCACGCCATGGCCCGCATCGCCGCCGCGCACGACGATGATGCCGTGGCAGGCGCCCGAGCCCAGGCCGACTACCTGAAGA
AGTTCCTTGCCGATTCCATCGTGCGTGACTTCGAACATCTGCGCCTGACCGAATTCGGTGGCCGCAAGTGGGTGACGATG
GGCCAAAGCTACGGCGGCTTCCTGACCCTGACCACACTGTCCCTGTTCCCGGCCGGCGTAATCGCCAGCTTCACCACCGG
CGGCATCCCGCACGTGCCGGCCGACGCCGCTGAAGTGTACGAGCATACCTTCCCGCGCATGGTGCGCAAGACGACTCAGT
TCTACGAGCGCTACCCACAGGACAAGGAGCGCGTGGCCGCCATCGCCGACAAGCTGCCGACTACTGCGGAAGTCGCCGAA
TTCGTTGGCAAACTCACCGATTCCGTACTGAATCCGATGGCTGGTACCGATGTGGAGCATCGACTTGGCGTGATCGCCGG
CATGGCCGCCCACGGCTTCCCGCTGCTGCCGAACGGCGACCCACTCACCGTCGAACGGTTCCAGTGCCTTGGCGGTGACT
TCGGCATGAAACCCAGCTTCGAGCGCGTCCACTGGATTCTCGACGACGCCTTCCTCGACGGCGACGGCACCGTGCGTGAC
GGATCGCCGCTGTCCGACGAATTCCTGTCCAAGGTGATGGCCGCCACGTCGTCGCGCCCGCTGTATTGGCCGTTGCAGGA
ATTCATCTACGCCAACGGCGAGCTTGACGAGCCCATTCGCTGGGCCGCCCAGCGCGTGCGCGATGGCAAGCCCGAATTCG
ATGCCGTTGCGCGTCCGCTCAACTTCACCGGCGAGGCCATGTTCCCGTGGATGTTCGAACAGGAGTCTGCGTTACGCCCG
TTCAGGCCGGCCATGGACCTGCTCATGGAAGACACGCACTTCGGCGTGATCTATGACGAAGAACAGCTGGCCCGCAATGA
GGTGCCGTTGCAGGCCGCCGTCTATTTCGACGATATGTACGTCGATTCCGGCCTGCAGCTCGACACCTTGAGCCGCGTGG
GTAACAGCCACTACTGGACCACCAACGAATTCGAGCATGATGGTCTGCACGGCCCGCTCGTCTTCAAGCATCTCTATGAC
GAAGCCCTCAACCGGGGCGATCTTGAAGCATTGTTCTGA

Upstream 100 bases:

>100_bases
TCATCTCCATAACGCACAAGGCTAGCGTGTCCGGAGACGAACCGGTATCACTCTTCAGGAGGATTTGTGGACTAGAGTTT
GTGGACTAGAGTCTTGAACC

Downstream 100 bases:

>100_bases
CTCAAGGAAGCAAGCTCCCTCTGATGAGGGAGCTCTGTATACATGCACGAAAGGAAAACGTATGACTCAGAACCTCACCA
TCGGTTTTATCGGATATGGC

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 492; Mature: 491

Protein sequence:

>492_residues
MTMLSKYHVPGLAIEDHSIDVPLDWTGHEPGRAFDGETIKLFYRVVTAPEHVHDDLPLLIFLQGGPGGAGPRLNSPTSDG
WIEEAIRHFRVILPDQRGTGRSSRVDTHAMARIAAAHDDDAVAGARAQADYLKKFLADSIVRDFEHLRLTEFGGRKWVTM
GQSYGGFLTLTTLSLFPAGVIASFTTGGIPHVPADAAEVYEHTFPRMVRKTTQFYERYPQDKERVAAIADKLPTTAEVAE
FVGKLTDSVLNPMAGTDVEHRLGVIAGMAAHGFPLLPNGDPLTVERFQCLGGDFGMKPSFERVHWILDDAFLDGDGTVRD
GSPLSDEFLSKVMAATSSRPLYWPLQEFIYANGELDEPIRWAAQRVRDGKPEFDAVARPLNFTGEAMFPWMFEQESALRP
FRPAMDLLMEDTHFGVIYDEEQLARNEVPLQAAVYFDDMYVDSGLQLDTLSRVGNSHYWTTNEFEHDGLHGPLVFKHLYD
EALNRGDLEALF

Sequences:

>Translated_492_residues
MTMLSKYHVPGLAIEDHSIDVPLDWTGHEPGRAFDGETIKLFYRVVTAPEHVHDDLPLLIFLQGGPGGAGPRLNSPTSDG
WIEEAIRHFRVILPDQRGTGRSSRVDTHAMARIAAAHDDDAVAGARAQADYLKKFLADSIVRDFEHLRLTEFGGRKWVTM
GQSYGGFLTLTTLSLFPAGVIASFTTGGIPHVPADAAEVYEHTFPRMVRKTTQFYERYPQDKERVAAIADKLPTTAEVAE
FVGKLTDSVLNPMAGTDVEHRLGVIAGMAAHGFPLLPNGDPLTVERFQCLGGDFGMKPSFERVHWILDDAFLDGDGTVRD
GSPLSDEFLSKVMAATSSRPLYWPLQEFIYANGELDEPIRWAAQRVRDGKPEFDAVARPLNFTGEAMFPWMFEQESALRP
FRPAMDLLMEDTHFGVIYDEEQLARNEVPLQAAVYFDDMYVDSGLQLDTLSRVGNSHYWTTNEFEHDGLHGPLVFKHLYD
EALNRGDLEALF
>Mature_491_residues
TMLSKYHVPGLAIEDHSIDVPLDWTGHEPGRAFDGETIKLFYRVVTAPEHVHDDLPLLIFLQGGPGGAGPRLNSPTSDGW
IEEAIRHFRVILPDQRGTGRSSRVDTHAMARIAAAHDDDAVAGARAQADYLKKFLADSIVRDFEHLRLTEFGGRKWVTMG
QSYGGFLTLTTLSLFPAGVIASFTTGGIPHVPADAAEVYEHTFPRMVRKTTQFYERYPQDKERVAAIADKLPTTAEVAEF
VGKLTDSVLNPMAGTDVEHRLGVIAGMAAHGFPLLPNGDPLTVERFQCLGGDFGMKPSFERVHWILDDAFLDGDGTVRDG
SPLSDEFLSKVMAATSSRPLYWPLQEFIYANGELDEPIRWAAQRVRDGKPEFDAVARPLNFTGEAMFPWMFEQESALRPF
RPAMDLLMEDTHFGVIYDEEQLARNEVPLQAAVYFDDMYVDSGLQLDTLSRVGNSHYWTTNEFEHDGLHGPLVFKHLYDE
ALNRGDLEALF

Specific function: Higher activity toward long peptides. Acts on hydroxyproline beta-naphthylamide with almost as high an activity as on proline beta-naphthylamide [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 54898; Mature: 54767

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMLSKYHVPGLAIEDHSIDVPLDWTGHEPGRAFDGETIKLFYRVVTAPEHVHDDLPLLI
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHEEHHHHHCCHHHHCCCCCEEE
FLQGGPGGAGPRLNSPTSDGWIEEAIRHFRVILPDQRGTGRSSRVDTHAMARIAAAHDDD
EEECCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHCCCCC
AVAGARAQADYLKKFLADSIVRDFEHLRLTEFGGRKWVTMGQSYGGFLTLTTLSLFPAGV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHH
IASFTTGGIPHVPADAAEVYEHTFPRMVRKTTQFYERYPQDKERVAAIADKLPTTAEVAE
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
FVGKLTDSVLNPMAGTDVEHRLGVIAGMAAHGFPLLPNGDPLTVERFQCLGGDFGMKPSF
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCH
ERVHWILDDAFLDGDGTVRDGSPLSDEFLSKVMAATSSRPLYWPLQEFIYANGELDEPIR
HHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECHHHHHCCCCCCCHHHH
WAAQRVRDGKPEFDAVARPLNFTGEAMFPWMFEQESALRPFRPAMDLLMEDTHFGVIYDE
HHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECH
EQLARNEVPLQAAVYFDDMYVDSGLQLDTLSRVGNSHYWTTNEFEHDGLHGPLVFKHLYD
HHHHHCCCCEEEEEEEEHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EALNRGDLEALF
HHCCCCCHHHCC
>Mature Secondary Structure 
TMLSKYHVPGLAIEDHSIDVPLDWTGHEPGRAFDGETIKLFYRVVTAPEHVHDDLPLLI
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHHEEHHHHHCCHHHHCCCCCEEE
FLQGGPGGAGPRLNSPTSDGWIEEAIRHFRVILPDQRGTGRSSRVDTHAMARIAAAHDDD
EEECCCCCCCCCCCCCCCCHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHCCCCC
AVAGARAQADYLKKFLADSIVRDFEHLRLTEFGGRKWVTMGQSYGGFLTLTTLSLFPAGV
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHH
IASFTTGGIPHVPADAAEVYEHTFPRMVRKTTQFYERYPQDKERVAAIADKLPTTAEVAE
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHH
FVGKLTDSVLNPMAGTDVEHRLGVIAGMAAHGFPLLPNGDPLTVERFQCLGGDFGMKPSF
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCCH
ERVHWILDDAFLDGDGTVRDGSPLSDEFLSKVMAATSSRPLYWPLQEFIYANGELDEPIR
HHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECHHHHHCCCCCCCHHHH
WAAQRVRDGKPEFDAVARPLNFTGEAMFPWMFEQESALRPFRPAMDLLMEDTHFGVIYDE
HHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECH
EQLARNEVPLQAAVYFDDMYVDSGLQLDTLSRVGNSHYWTTNEFEHDGLHGPLVFKHLYD
HHHHHCCCCEEEEEEEEHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EALNRGDLEALF
HHCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7883756 [H]