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The map label for this gene is hemN [H]

Identifier: 213692358

GI number: 213692358

Start: 1654634

End: 1655812

Strand: Reverse

Name: hemN [H]

Synonym: Blon_1485

Alternate gene names: 213692358

Gene position: 1655812-1654634 (Counterclockwise)

Preceding gene: 213692359

Following gene: 213692357

Centisome position: 58.45

GC content: 63.1

Gene sequence:

>1179_bases
TTGACTTACGAGATCTACATTCATGTGCCGTTCTGTCTGCGGCGGTGCGGCTACTGCGATTTCAACACCTATACGGCCAC
GGACCTCGGTGCGGGCGCCTCGCGCGGTCATTACGCCCAGATGGTCATCCGGGAGATGGCTCTGATCAGGCAATGGCAGT
GCGATCACGGCATCGAGGAGCCTGCCGCTTCCACCGTGTTCTTCGGCGGAGGCACTCCCACGGTTCTCGCCGCCGCCGAT
CTGGTGGCCGTGGTGGATGCCATCCGCGCGATCTGGGGTCTGACGCCCGACGCCGAGATCACCACCGAAGCCAACCCGGA
TACGGTCGATGAGGCTTACATAGCCGAGCTTGCCGACGGCGGTTTCACCCGCATATCCTTCGGCATGCAGTCAGCCGTGC
CGCACGTGCTGGCGACGCTCGACCGCACGCACACGCCGTCCAACGTGGCCGCCGGCGTCGACGCCGCCACCATGGCCGGA
CTGCGTTCCAGCGTGGATCTGATCTACGGCGCGCCGGGGGAGAGCCTTGAGGATTGGCGCACTTCGGTTGAGGCCGCTCT
CGATCTCGGTGTGCATCATATCTCCGCTTATGCGCTGACCGTGGAACCCACCACGAAAATGGGCCGTCGGATCGCCGCCG
GCACCTTGCCCAAGCCGGATGACGATGATGAGGCCGCCAAATACGAGCTCGCCGACGAGCTGTTCACCCAAGCCGGTCTT
GATTGGTATGAGATTTCCAACTGGGCCCGCCCCGGATACGAGAGCCGGCATAATCTCGGGTATTGGCGCAACGTCGATTG
GGCGGGGCTGGGTCCCGGCGCCCATTCCCATTACCGTTGCCATGCGATGTCTTCCAATGGGTACGGCCTGCGCAGTTGGG
ACATCGCCCACCCCCGTCTCTGGGGAGTCGCCATTAATGAACACCGTGTGCCATGGGCCGATAGTGAGCGGATCACCGCC
GAGGAGAACCTCGAGGAACTGATCATGCTTGGTCTGCGTATGCGTGAAGGGCTCGATCTGGAGCGCATCGATCGCGTCAT
TGCCGTGGATCGGCTTACGCCGATGATCGAAGAGGGCCTGGTCACCGTGGTCGATGGACGCCGGGTGGTGCCCACGCGGC
GCGGCAGGCTCATCAATGACACGGTCATCGAACGGTTCTTCGATCTCGCCGGTATCTAG

Upstream 100 bases:

>100_bases
AGACAAGATTCGCGCCGCGCAGAAGACGGAAGGCTGAGCGGGTGCCGGAGGCTCGCCTCGCCGGGGAGTCTTCGGCACGG
ATGGCTGAGGGGAGTGACGG

Downstream 100 bases:

>100_bases
GACCGGAGCGTCGTGGAGTATGCTCGAATCATGACGCGCTACCTATGCGCCCCCGACTCCTTCAAAGAGAGCTTGACCGC
CATGCAGGCGGCCGAGGCGA

Product: oxygen-independent coproporphyrinogen III oxidase

Products: NA

Alternate protein names: Coprogen oxidase; Coproporphyrinogenase [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTYEIYIHVPFCLRRCGYCDFNTYTATDLGAGASRGHYAQMVIREMALIRQWQCDHGIEEPAASTVFFGGGTPTVLAAAD
LVAVVDAIRAIWGLTPDAEITTEANPDTVDEAYIAELADGGFTRISFGMQSAVPHVLATLDRTHTPSNVAAGVDAATMAG
LRSSVDLIYGAPGESLEDWRTSVEAALDLGVHHISAYALTVEPTTKMGRRIAAGTLPKPDDDDEAAKYELADELFTQAGL
DWYEISNWARPGYESRHNLGYWRNVDWAGLGPGAHSHYRCHAMSSNGYGLRSWDIAHPRLWGVAINEHRVPWADSERITA
EENLEELIMLGLRMREGLDLERIDRVIAVDRLTPMIEEGLVTVVDGRRVVPTRRGRLINDTVIERFFDLAGI

Sequences:

>Translated_392_residues
MTYEIYIHVPFCLRRCGYCDFNTYTATDLGAGASRGHYAQMVIREMALIRQWQCDHGIEEPAASTVFFGGGTPTVLAAAD
LVAVVDAIRAIWGLTPDAEITTEANPDTVDEAYIAELADGGFTRISFGMQSAVPHVLATLDRTHTPSNVAAGVDAATMAG
LRSSVDLIYGAPGESLEDWRTSVEAALDLGVHHISAYALTVEPTTKMGRRIAAGTLPKPDDDDEAAKYELADELFTQAGL
DWYEISNWARPGYESRHNLGYWRNVDWAGLGPGAHSHYRCHAMSSNGYGLRSWDIAHPRLWGVAINEHRVPWADSERITA
EENLEELIMLGLRMREGLDLERIDRVIAVDRLTPMIEEGLVTVVDGRRVVPTRRGRLINDTVIERFFDLAGI
>Mature_391_residues
TYEIYIHVPFCLRRCGYCDFNTYTATDLGAGASRGHYAQMVIREMALIRQWQCDHGIEEPAASTVFFGGGTPTVLAAADL
VAVVDAIRAIWGLTPDAEITTEANPDTVDEAYIAELADGGFTRISFGMQSAVPHVLATLDRTHTPSNVAAGVDAATMAGL
RSSVDLIYGAPGESLEDWRTSVEAALDLGVHHISAYALTVEPTTKMGRRIAAGTLPKPDDDDEAAKYELADELFTQAGLD
WYEISNWARPGYESRHNLGYWRNVDWAGLGPGAHSHYRCHAMSSNGYGLRSWDIAHPRLWGVAINEHRVPWADSERITAE
ENLEELIMLGLRMREGLDLERIDRVIAVDRLTPMIEEGLVTVVDGRRVVPTRRGRLINDTVIERFFDLAGI

Specific function: Anaerobic transformation of coproporphyrinogen-III into protoporphyrinogen-IX [H]

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=275, Percent_Identity=33.4545454545455, Blast_Score=159, Evalue=4e-39,
Organism=Escherichia coli, GI1789325, Length=397, Percent_Identity=31.9899244332494, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI87082341, Length=253, Percent_Identity=25.6916996047431, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: =1.3.99.22 [H]

Molecular weight: Translated: 43258; Mature: 43127

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYEIYIHVPFCLRRCGYCDFNTYTATDLGAGASRGHYAQMVIREMALIRQWQCDHGIEE
CEEEEEEECHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PAASTVFFGGGTPTVLAAADLVAVVDAIRAIWGLTPDAEITTEANPDTVDEAYIAELADG
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHCCC
GFTRISFGMQSAVPHVLATLDRTHTPSNVAAGVDAATMAGLRSSVDLIYGAPGESLEDWR
CCEEEHHCHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHCCEEEECCCCCCHHHHH
TSVEAALDLGVHHISAYALTVEPTTKMGRRIAAGTLPKPDDDDEAAKYELADELFTQAGL
HHHHHHHHHHHHEEEEEEEEECCHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DWYEISNWARPGYESRHNLGYWRNVDWAGLGPGAHSHYRCHAMSSNGYGLRSWDIAHPRL
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCEE
WGVAINEHRVPWADSERITAEENLEELIMLGLRMREGLDLERIDRVIAVDRLTPMIEEGL
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
VTVVDGRRVVPTRRGRLINDTVIERFFDLAGI
EEEECCCEECCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TYEIYIHVPFCLRRCGYCDFNTYTATDLGAGASRGHYAQMVIREMALIRQWQCDHGIEE
EEEEEEECHHHHHHCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PAASTVFFGGGTPTVLAAADLVAVVDAIRAIWGLTPDAEITTEANPDTVDEAYIAELADG
CCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHCCC
GFTRISFGMQSAVPHVLATLDRTHTPSNVAAGVDAATMAGLRSSVDLIYGAPGESLEDWR
CCEEEHHCHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHCCEEEECCCCCCHHHHH
TSVEAALDLGVHHISAYALTVEPTTKMGRRIAAGTLPKPDDDDEAAKYELADELFTQAGL
HHHHHHHHHHHHEEEEEEEEECCHHHHCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHCC
DWYEISNWARPGYESRHNLGYWRNVDWAGLGPGAHSHYRCHAMSSNGYGLRSWDIAHPRL
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEECCCCCEE
WGVAINEHRVPWADSERITAEENLEELIMLGLRMREGLDLERIDRVIAVDRLTPMIEEGL
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
VTVVDGRRVVPTRRGRLINDTVIERFFDLAGI
EEEECCCEECCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]