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The map label for this gene is tenA [H]

Identifier: 213692335

GI number: 213692335

Start: 1621317

End: 1622051

Strand: Reverse

Name: tenA [H]

Synonym: Blon_1460

Alternate gene names: 213692335

Gene position: 1622051-1621317 (Counterclockwise)

Preceding gene: 213692338

Following gene: 213692334

Centisome position: 57.26

GC content: 60.82

Gene sequence:

>735_bases
ATGTCTTTTGACGCCGTCGCATTCGGCCCGATCACCCTGAACCACCTGCCGCCGTTCGCCCAGCGCCTGCGCCAGGCCTC
CGACCTGGTCTGGGAGGAGGGCTACCGGCAGCCGTTCCTGCGCGAGCTGGGTCACGGCACGCTTTCGCGCGAGCGCTTCG
CGTTCTACCTGCTGCAGGATTACCGCTACCTGAACGATTACGCCAAGGTGCACGCGCTGGCGTTGACCAAGACCCAGGAT
CCCGAGGTCATGCGGTTCATGGCGGATGTGCAGAACGGCATCTTCAATGTGGAATCCGCCATGCATCGTAAATACATGGC
GAGCTACGGCATCAGCGAGCAGGAGATGAACTCGGTGCGCCAGTCTGCGTTCGCCCGCGCCTACACGTCGAACATCCTGT
CGATCGCATACGGCAATCCGCTGGTTGATATCCTGGTCGCCGTGCTGCCCTGCGCCTGGGTGTACGCCGACTACGGTCAG
CGTCTCGCCGCCGAATTCGCGGACACGCTCGATGCCAACCCGTACAAGAGCTGGGTGGACATGTACAAGACCGAGGAGTT
CTGGAGTAGCTCGGCGTGGCTGATTGAACACATCGAACAGCTCGTGGAGGGTTTGAACGAAGAGCGCCGGGCCGAGCTCG
TGGACATCTTCGTGACCGGTGTGCAGAACGAATACCTGTTCTGGTCAAGCGCCTACGACATACAGTACACGTGGAAACCC
GAATGGGATGTGTGA

Upstream 100 bases:

>100_bases
GAATGCAAGCTGCCGGCCATCGTGGTGGCGAACGGGTTGAGAAAGGCGCTGTGCCTGACCCTTGGAGCCTGTTGGCCAAC
ACCATCGAAGGGGGCAAACG

Downstream 100 bases:

>100_bases
GGCGCACGATGGATGAGCGGTGGGCGCGTGCTTTGCACGCCAAGGGCATTGATATTGACGAGGCTGAAGGTGCTGGTGGG
AAACGGGCGCACGACGGCAA

Product: transcriptional activator, TenA family

Products: NA

Alternate protein names: Thiaminase II; Transcriptional activator tenA [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSFDAVAFGPITLNHLPPFAQRLRQASDLVWEEGYRQPFLRELGHGTLSRERFAFYLLQDYRYLNDYAKVHALALTKTQD
PEVMRFMADVQNGIFNVESAMHRKYMASYGISEQEMNSVRQSAFARAYTSNILSIAYGNPLVDILVAVLPCAWVYADYGQ
RLAAEFADTLDANPYKSWVDMYKTEEFWSSSAWLIEHIEQLVEGLNEERRAELVDIFVTGVQNEYLFWSSAYDIQYTWKP
EWDV

Sequences:

>Translated_244_residues
MSFDAVAFGPITLNHLPPFAQRLRQASDLVWEEGYRQPFLRELGHGTLSRERFAFYLLQDYRYLNDYAKVHALALTKTQD
PEVMRFMADVQNGIFNVESAMHRKYMASYGISEQEMNSVRQSAFARAYTSNILSIAYGNPLVDILVAVLPCAWVYADYGQ
RLAAEFADTLDANPYKSWVDMYKTEEFWSSSAWLIEHIEQLVEGLNEERRAELVDIFVTGVQNEYLFWSSAYDIQYTWKP
EWDV
>Mature_243_residues
SFDAVAFGPITLNHLPPFAQRLRQASDLVWEEGYRQPFLRELGHGTLSRERFAFYLLQDYRYLNDYAKVHALALTKTQDP
EVMRFMADVQNGIFNVESAMHRKYMASYGISEQEMNSVRQSAFARAYTSNILSIAYGNPLVDILVAVLPCAWVYADYGQR
LAAEFADTLDANPYKSWVDMYKTEEFWSSSAWLIEHIEQLVEGLNEERRAELVDIFVTGVQNEYLFWSSAYDIQYTWKPE
WDV

Specific function: Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with degS and degU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency [H]

COG id: COG0819

COG function: function code K; Putative transcription activator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiaminase-2 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324517, Length=208, Percent_Identity=23.5576923076923, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6325378, Length=207, Percent_Identity=23.1884057971014, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: =3.5.99.2 [H]

Molecular weight: Translated: 28382; Mature: 28251

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDAVAFGPITLNHLPPFAQRLRQASDLVWEEGYRQPFLRELGHGTLSRERFAFYLLQD
CCCCCEEECCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHH
YRYLNDYAKVHALALTKTQDPEVMRFMADVQNGIFNVESAMHRKYMASYGISEQEMNSVR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHH
QSAFARAYTSNILSIAYGNPLVDILVAVLPCAWVYADYGQRLAAEFADTLDANPYKSWVD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MYKTEEFWSSSAWLIEHIEQLVEGLNEERRAELVDIFVTGVQNEYLFWSSAYDIQYTWKP
HHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCEEEEEECCC
EWDV
CCCC
>Mature Secondary Structure 
SFDAVAFGPITLNHLPPFAQRLRQASDLVWEEGYRQPFLRELGHGTLSRERFAFYLLQD
CCCCEEECCEECCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHHHH
YRYLNDYAKVHALALTKTQDPEVMRFMADVQNGIFNVESAMHRKYMASYGISEQEMNSVR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHH
QSAFARAYTSNILSIAYGNPLVDILVAVLPCAWVYADYGQRLAAEFADTLDANPYKSWVD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
MYKTEEFWSSSAWLIEHIEQLVEGLNEERRAELVDIFVTGVQNEYLFWSSAYDIQYTWKP
HHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCEEEEEECCC
EWDV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1898926; 9384377 [H]