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The map label for this gene is dnaN [H]

Identifier: 213692129

GI number: 213692129

Start: 1434589

End: 1435662

Strand: Reverse

Name: dnaN [H]

Synonym: Blon_1249

Alternate gene names: 213692129

Gene position: 1435662-1434589 (Counterclockwise)

Preceding gene: 213692130

Following gene: 213692126

Centisome position: 50.68

GC content: 67.97

Gene sequence:

>1074_bases
ATGGTGAGGGTATTGGTCGATGCGAGGGAGTTCGCGAACATGGTCGCGCATGCGGCGCGCGTGCTGGAGCGCGACAACCC
GTATGTCGCGTTGGATGCCGCGGATGACGGCCTGGCGATCAGCGCGGCGGGCGACAGCCAGTGGTCGCATGGCCGTGTGG
ACGCGACCGTCCTGGAGGCGGGTTCCGCGGTCGTGTCGGGCCTGTGGCTGAACGCGTTGGCGAACGCGATGCCGTCGGGC
GAGATCGGCGTGGAGACGAATGGCGGGTATCTGACGTTGCGTGGCGGCGAGGCGTCGCTGCGCATGCGTGTCGGCGAGGA
GAAGGATCGTCCGGCCGAACCGGCCGCCCCGGAGCGGATGGTGCCCGTGGACGCGGACGCGTACGCCGCGTTGTGCGGCA
GCGTCGCCCCGGAGGCGGGCGGCACGAGGGACCAGCCGGTCCTCGCGTCCGTCAGATTCGTCGCGGCCGGCGGCCTGCTG
ACGGCGACGGCCACGAACCGGTACATGGCCGGCCGCCGGTCCATCCCGGTCGGCGGCATGCCGGACGGCGAATGGCTGGC
GGACGCGGATTGGGTGAAACGCAACGCGAAGGGGGTGAACGCGATCGGGTTCACGGACCGGATGATGGTCGTGGATACGG
GCGGGTTCACGGACGCGATCGTGCTGACCGCCGGACAGTATCCGATGGTGGACCGCCTGTTCGACAAACCGGAGGAGCCG
GCGGGCGTGGCGGTCGTGGACAGGCGCGCCCTGATGGATGCGGCGCGCATGCTGAAAAGCGTCTGCTTCGACTCGCGCAT
GGGCATTATCCCGCTGATCCTGGATGAGCGGGACGGGATGCTTCGTGTCCGGTATGCGGGCGACGGGCAGGATGCGGATT
CGCAGGGCGTGCGTCTCCTGGAGGCGGACATCACGGGGGATGTGAACGTGAAACTGAACGCGGATTACCTGCTGACCGTG
CTTGCGGGCATGGATGCGGACAGGGTGTCGGTGGTGAAGACCCGTGAGATGAAGCCCGTCCTGTTCGAACAGGACGATTC
CGCGGTGGAGCAATTGGTGATGCCCGTCTGTTAG

Upstream 100 bases:

>100_bases
CTGCCTCCCATGATCCTGTCCGTCCCCCATTTCGACGCGGGCGCGCCCGTGTGACGCATACCCGGGTCGCAAACCGTTGT
TTTCGTGTGGAAAGGACATG

Downstream 100 bases:

>100_bases
GATCGTCCCCGACATGCGGGAAAAGGGGTGTCGCGTCCGTCCGGGCGCGACACCCCTTTTTTTGTTCGGTCCGGATCGTC
AGGGGCGCGCGTCGTGCGCG

Product: DNA polymerase III, beta subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MVRVLVDAREFANMVAHAARVLERDNPYVALDAADDGLAISAAGDSQWSHGRVDATVLEAGSAVVSGLWLNALANAMPSG
EIGVETNGGYLTLRGGEASLRMRVGEEKDRPAEPAAPERMVPVDADAYAALCGSVAPEAGGTRDQPVLASVRFVAAGGLL
TATATNRYMAGRRSIPVGGMPDGEWLADADWVKRNAKGVNAIGFTDRMMVVDTGGFTDAIVLTAGQYPMVDRLFDKPEEP
AGVAVVDRRALMDAARMLKSVCFDSRMGIIPLILDERDGMLRVRYAGDGQDADSQGVRLLEADITGDVNVKLNADYLLTV
LAGMDADRVSVVKTREMKPVLFEQDDSAVEQLVMPVC

Sequences:

>Translated_357_residues
MVRVLVDAREFANMVAHAARVLERDNPYVALDAADDGLAISAAGDSQWSHGRVDATVLEAGSAVVSGLWLNALANAMPSG
EIGVETNGGYLTLRGGEASLRMRVGEEKDRPAEPAAPERMVPVDADAYAALCGSVAPEAGGTRDQPVLASVRFVAAGGLL
TATATNRYMAGRRSIPVGGMPDGEWLADADWVKRNAKGVNAIGFTDRMMVVDTGGFTDAIVLTAGQYPMVDRLFDKPEEP
AGVAVVDRRALMDAARMLKSVCFDSRMGIIPLILDERDGMLRVRYAGDGQDADSQGVRLLEADITGDVNVKLNADYLLTV
LAGMDADRVSVVKTREMKPVLFEQDDSAVEQLVMPVC
>Mature_357_residues
MVRVLVDAREFANMVAHAARVLERDNPYVALDAADDGLAISAAGDSQWSHGRVDATVLEAGSAVVSGLWLNALANAMPSG
EIGVETNGGYLTLRGGEASLRMRVGEEKDRPAEPAAPERMVPVDADAYAALCGSVAPEAGGTRDQPVLASVRFVAAGGLL
TATATNRYMAGRRSIPVGGMPDGEWLADADWVKRNAKGVNAIGFTDRMMVVDTGGFTDAIVLTAGQYPMVDRLFDKPEEP
AGVAVVDRRALMDAARMLKSVCFDSRMGIIPLILDERDGMLRVRYAGDGQDADSQGVRLLEADITGDVNVKLNADYLLTV
LAGMDADRVSVVKTREMKPVLFEQDDSAVEQLVMPVC

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped

COG id: COG0592

COG function: function code L; DNA polymerase sliding clamp subunit (PCNA homolog)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001001
- InterPro:   IPR022635
- InterPro:   IPR022637
- InterPro:   IPR022634 [H]

Pfam domain/function: PF00712 DNA_pol3_beta; PF02767 DNA_pol3_beta_2; PF02768 DNA_pol3_beta_3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 37984; Mature: 37984

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRVLVDAREFANMVAHAARVLERDNPYVALDAADDGLAISAAGDSQWSHGRVDATVLEA
CEEEEECHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEEEECC
GSAVVSGLWLNALANAMPSGEIGVETNGGYLTLRGGEASLRMRVGEEKDRPAEPAAPERM
CHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCE
VPVDADAYAALCGSVAPEAGGTRDQPVLASVRFVAAGGLLTATATNRYMAGRRSIPVGGM
ECCCCHHHHHHHCCCCCCCCCCCCCCHHHEEEEEECCCEEEEECCCHHHCCCCCCCCCCC
PDGEWLADADWVKRNAKGVNAIGFTDRMMVVDTGGFTDAIVLTAGQYPMVDRLFDKPEEP
CCCCEECCHHHHHHCCCCCEEECCCCEEEEEECCCCCEEEEEECCCCCHHHHHHCCCCCC
AGVAVVDRRALMDAARMLKSVCFDSRMGIIPLILDERDGMLRVRYAGDGQDADSQGVRLL
CCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCEEE
EADITGDVNVKLNADYLLTVLAGMDADRVSVVKTREMKPVLFEQDDSAVEQLVMPVC
EECCCCCEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHCCC
>Mature Secondary Structure
MVRVLVDAREFANMVAHAARVLERDNPYVALDAADDGLAISAAGDSQWSHGRVDATVLEA
CEEEEECHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCCCCCCEEEEECC
GSAVVSGLWLNALANAMPSGEIGVETNGGYLTLRGGEASLRMRVGEEKDRPAEPAAPERM
CHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCE
VPVDADAYAALCGSVAPEAGGTRDQPVLASVRFVAAGGLLTATATNRYMAGRRSIPVGGM
ECCCCHHHHHHHCCCCCCCCCCCCCCHHHEEEEEECCCEEEEECCCHHHCCCCCCCCCCC
PDGEWLADADWVKRNAKGVNAIGFTDRMMVVDTGGFTDAIVLTAGQYPMVDRLFDKPEEP
CCCCEECCHHHHHHCCCCCEEECCCCEEEEEECCCCCEEEEEECCCCCHHHHHHCCCCCC
AGVAVVDRRALMDAARMLKSVCFDSRMGIIPLILDERDGMLRVRYAGDGQDADSQGVRLL
CCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCEEE
EADITGDVNVKLNADYLLTVLAGMDADRVSVVKTREMKPVLFEQDDSAVEQLVMPVC
EECCCCCEEEEECCHHHHHHHHCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1577691; 12000953 [H]