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The map label for this gene is yciL [C]

Identifier: 213692048

GI number: 213692048

Start: 1348548

End: 1349318

Strand: Direct

Name: yciL [C]

Synonym: Blon_1166

Alternate gene names: 213692048

Gene position: 1348548-1349318 (Clockwise)

Preceding gene: 213692046

Following gene: 213692049

Centisome position: 47.61

GC content: 59.92

Gene sequence:

>771_bases
ATGCCAAACGCATATTCCCGCGCTGCGAAAGCGCAAGACGATTCCAATTCCATTCGACTCCAGAAGCTGCTTGCCCAAGC
GGGATTCGGTTCCCGCCGCAAGTGCGAGGACATGATCACCGAAGGCCGTGTCGAGGTCGACGGTGAACTGGTCACCGAGC
TCGGAACTCGCGTTGACCCTCATAAGCAGCAGGTGCGCGTAGACGGTTCACGCGTACGCGTCAATCCGAACCACGTCACT
CTGGCACTGAACAAGCCCCGCAAGGTGCTCTCCGCCATGGACGATCCGAAGGGACGCTACACGTTGCGTGACATCGTGGG
CGACAAGTACGAGCGCATCTTCCACATGGGCCGTCTCGACTACGATTCCGAGGGTCTTATCCTCATGACGAACGATGGCG
AACTCTCGCAGCACGTCATGCACCCCAAGTACGAGGTCGAAAAGACCTACGTCGCCACGCTGGAGGGCAAGATCTCCGGT
ACCGTGTGCCGCCGACTCGTGACCACCGGCGTGCAGCTCGATGACGGTTGGATCAAACTCGACCACTGCGCCATCATCGA
CGCCTCCCGTGATTACACGATGGTCAAGGTCGTGCTGCACTCCGGCAAGAACCGCATCGTGCGCCGCATCTTCGGTTCGA
TCGGTTTCCCGGTCAAGCGTCTGGTGCGCACTCAGATCGGCCCGATCAAACTCGGTGATCTGAAGCCCGGTTCCTACCGC
GTGCTGTCCCAGACGGAAGTCCGTTCGCTGTCCAAGGAGGTTGGCCTGTGA

Upstream 100 bases:

>100_bases
GTTGGAATTGGCTGGGATTCCAGTCCGCCAACTCTAAAGTATGTATACAAATCGACAGTCTCTGCGATGACAGAATCTGT
CCGGCCACGTTGGGAGAACG

Downstream 100 bases:

>100_bases
TTCGCGTTGCCATCGACGGCCCCGCCGGCGTGGGCAAGTCGTCCACGTCCAAGGCGCTGGCCAAGTATTTCGGATACGCC
TACCTTGACACGGGCGCGAT

Product: pseudouridine synthase

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MPNAYSRAAKAQDDSNSIRLQKLLAQAGFGSRRKCEDMITEGRVEVDGELVTELGTRVDPHKQQVRVDGSRVRVNPNHVT
LALNKPRKVLSAMDDPKGRYTLRDIVGDKYERIFHMGRLDYDSEGLILMTNDGELSQHVMHPKYEVEKTYVATLEGKISG
TVCRRLVTTGVQLDDGWIKLDHCAIIDASRDYTMVKVVLHSGKNRIVRRIFGSIGFPVKRLVRTQIGPIKLGDLKPGSYR
VLSQTEVRSLSKEVGL

Sequences:

>Translated_256_residues
MPNAYSRAAKAQDDSNSIRLQKLLAQAGFGSRRKCEDMITEGRVEVDGELVTELGTRVDPHKQQVRVDGSRVRVNPNHVT
LALNKPRKVLSAMDDPKGRYTLRDIVGDKYERIFHMGRLDYDSEGLILMTNDGELSQHVMHPKYEVEKTYVATLEGKISG
TVCRRLVTTGVQLDDGWIKLDHCAIIDASRDYTMVKVVLHSGKNRIVRRIFGSIGFPVKRLVRTQIGPIKLGDLKPGSYR
VLSQTEVRSLSKEVGL
>Mature_255_residues
PNAYSRAAKAQDDSNSIRLQKLLAQAGFGSRRKCEDMITEGRVEVDGELVTELGTRVDPHKQQVRVDGSRVRVNPNHVTL
ALNKPRKVLSAMDDPKGRYTLRDIVGDKYERIFHMGRLDYDSEGLILMTNDGELSQHVMHPKYEVEKTYVATLEGKISGT
VCRRLVTTGVQLDDGWIKLDHCAIIDASRDYTMVKVVLHSGKNRIVRRIFGSIGFPVKRLVRTQIGPIKLGDLKPGSYRV
LSQTEVRSLSKEVGL

Specific function: Unknown

COG id: COG1187

COG function: function code J; 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787524, Length=221, Percent_Identity=38.0090497737557, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1788510, Length=234, Percent_Identity=32.9059829059829, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790453, Length=239, Percent_Identity=30.9623430962343, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI87081838, Length=204, Percent_Identity=30.3921568627451, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006145
- InterPro:   IPR000748
- InterPro:   IPR018496
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2; PF01479 S4 [H]

EC number: NA

Molecular weight: Translated: 28757; Mature: 28625

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50889 S4 ; PS01149 PSI_RSU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNAYSRAAKAQDDSNSIRLQKLLAQAGFGSRRKCEDMITEGRVEVDGELVTELGTRVDP
CCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECHHHHHHHCCCCCC
HKQQVRVDGSRVRVNPNHVTLALNKPRKVLSAMDDPKGRYTLRDIVGDKYERIFHMGRLD
CHHHEEECCCEEEECCCEEEEEECCCHHHHHHCCCCCCCEEHHHHHCHHHHHHHHHCCCC
YDSEGLILMTNDGELSQHVMHPKYEVEKTYVATLEGKISGTVCRRLVTTGVQLDDGWIKL
CCCCCEEEEECCCCHHHHHCCCCHHHCCEEEEEECCCHHHHHHHHHHHCCCEECCCEEEE
DHCAIIDASRDYTMVKVVLHSGKNRIVRRIFGSIGFPVKRLVRTQIGPIKLGDLKPGSYR
EEEEEEECCCCCEEEEEEHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCEE
VLSQTEVRSLSKEVGL
EECHHHHHHHHHHHCC
>Mature Secondary Structure 
PNAYSRAAKAQDDSNSIRLQKLLAQAGFGSRRKCEDMITEGRVEVDGELVTELGTRVDP
CCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHCCCEEECHHHHHHHCCCCCC
HKQQVRVDGSRVRVNPNHVTLALNKPRKVLSAMDDPKGRYTLRDIVGDKYERIFHMGRLD
CHHHEEECCCEEEECCCEEEEEECCCHHHHHHCCCCCCCEEHHHHHCHHHHHHHHHCCCC
YDSEGLILMTNDGELSQHVMHPKYEVEKTYVATLEGKISGTVCRRLVTTGVQLDDGWIKL
CCCCCEEEEECCCCHHHHHCCCCHHHCCEEEEEECCCHHHHHHHHHHHCCCEECCCEEEE
DHCAIIDASRDYTMVKVVLHSGKNRIVRRIFGSIGFPVKRLVRTQIGPIKLGDLKPGSYR
EEEEEEECCCCCEEEEEEHHCCCHHHHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCEE
VLSQTEVRSLSKEVGL
EECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]