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The map label for this gene is sucC [H]

Identifier: 213692043

GI number: 213692043

Start: 1341939

End: 1343141

Strand: Direct

Name: sucC [H]

Synonym: Blon_1161

Alternate gene names: 213692043

Gene position: 1341939-1343141 (Clockwise)

Preceding gene: 213692042

Following gene: 213692044

Centisome position: 47.37

GC content: 62.93

Gene sequence:

>1203_bases
ATGGATCTTTACGAATATCAGGCGCGTCAGCTGCTCGAGGAACAGGACATTCCCACCCCGAGCGCCATCTTCGCCCAGAA
CTCCCATGAAGTCGCGGAAGCGGCGGACGCAATCGGCTATCCATGCGTGATCAAGGCGCAGGTCAAGATCGGCCATCGCG
GTCAGGCTGGCGGCGTCAAGATCGCCCACAACCGCGACGAGGCCATTGTCGAATCCGAGTCCATTCTTCCGATGACCATA
CACGGCCACAAGGTCTCCGGCGTGCTCGTGGCCGAAGCCAAGAACATCCTGCATGAGTACTATGTGTCCATCTCCGTGGA
TCGCACCTCGCGCGACTTCGATGTGCTGGCCACCGCCAACGGCGGCACCGAGGTGGAGGAGATCGCCAAGGAGCATCCGG
AATCCGTCAAACGCCTGCACATCGACGCGCTCGGCGATTTCGATCTGGCCGCGGCCACCGAGATGGCCCGCAGCATCGGC
TTCTACCATGCCGACGTCGATCAGGCCGCGCAGATTCTGCTGAAGATGTGGCGCGTCTTCAAAGACAACGACGCCACACT
CGTGGAGATCAACCCTCTGGCCAAGATCGGCGACCCGGACGACGAGTCCACCAAGCAGCTGAGCGCCTTGGACGCCAAGA
TTTCCCTGGACGACAACGCCGCCTTCCGGCATGGTGGCTGGGAGCGATTCGTGGATTCCGTCGTCCCCGACCCCTTCGAG
CAGCGCGCCCGTGAGCACGGACTGCATTACGTGCATCTGCACGGCGAGGTCGGCGTGATCGGCAACGGTGCTGGACTCGT
CATGAGTTCCCTGGACGCCGTCTCCGGCGCCGGCGAGGAGCAGGGCAGCGATGTCAAACCCGCCAACTTCCTGGACATCG
GCGGCGGCGCCTCCGCCGCGGTCATGGCCGAGAGCCTGCAGATCGTCCTGTCCGACCCGCAGGTCGAATCCGTATTCATC
AACATATACGGCGGCATTACTTCCTGCGTGGAGGTCGCCAACGGCATTCTCGACGCCGTCGCCAAGCTCGGCGGTTCCAA
ACCCATCGTCGTGCGCTTCGACGGCAACGCGGCGGCCGAGGGTCTGCATATCCTCGCCTCCGCGAACAAACCGAATATCC
ATGTGTCCGAAACCATGGAAGACGCGGCGGCCAAGGCCGCGCAGCTCGCCGGTGAGGCGATTCAGTCCAAGGAGGTTCTC
TGA

Upstream 100 bases:

>100_bases
CTGAGCGTTCGTCTCACCCAACATACATTCGGTTTTTAAGGTCCGTCATGTACTGTGTACAGTTACATGACGGACCAATT
ACATAGTCAGGGAAGGATCG

Downstream 100 bases:

>100_bases
TGCTGTTCATCGAAGACGGCGCTCCGGTCATCGTCCAGGGCATGACCGGCCATCAGGGCATGACCCATACGGCGCGCATG
CTCAATGCCGGCACCAATAT

Product: Succinate--CoA ligase (ADP-forming)

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MDLYEYQARQLLEEQDIPTPSAIFAQNSHEVAEAADAIGYPCVIKAQVKIGHRGQAGGVKIAHNRDEAIVESESILPMTI
HGHKVSGVLVAEAKNILHEYYVSISVDRTSRDFDVLATANGGTEVEEIAKEHPESVKRLHIDALGDFDLAAATEMARSIG
FYHADVDQAAQILLKMWRVFKDNDATLVEINPLAKIGDPDDESTKQLSALDAKISLDDNAAFRHGGWERFVDSVVPDPFE
QRAREHGLHYVHLHGEVGVIGNGAGLVMSSLDAVSGAGEEQGSDVKPANFLDIGGGASAAVMAESLQIVLSDPQVESVFI
NIYGGITSCVEVANGILDAVAKLGGSKPIVVRFDGNAAAEGLHILASANKPNIHVSETMEDAAAKAAQLAGEAIQSKEVL

Sequences:

>Translated_400_residues
MDLYEYQARQLLEEQDIPTPSAIFAQNSHEVAEAADAIGYPCVIKAQVKIGHRGQAGGVKIAHNRDEAIVESESILPMTI
HGHKVSGVLVAEAKNILHEYYVSISVDRTSRDFDVLATANGGTEVEEIAKEHPESVKRLHIDALGDFDLAAATEMARSIG
FYHADVDQAAQILLKMWRVFKDNDATLVEINPLAKIGDPDDESTKQLSALDAKISLDDNAAFRHGGWERFVDSVVPDPFE
QRAREHGLHYVHLHGEVGVIGNGAGLVMSSLDAVSGAGEEQGSDVKPANFLDIGGGASAAVMAESLQIVLSDPQVESVFI
NIYGGITSCVEVANGILDAVAKLGGSKPIVVRFDGNAAAEGLHILASANKPNIHVSETMEDAAAKAAQLAGEAIQSKEVL
>Mature_400_residues
MDLYEYQARQLLEEQDIPTPSAIFAQNSHEVAEAADAIGYPCVIKAQVKIGHRGQAGGVKIAHNRDEAIVESESILPMTI
HGHKVSGVLVAEAKNILHEYYVSISVDRTSRDFDVLATANGGTEVEEIAKEHPESVKRLHIDALGDFDLAAATEMARSIG
FYHADVDQAAQILLKMWRVFKDNDATLVEINPLAKIGDPDDESTKQLSALDAKISLDDNAAFRHGGWERFVDSVVPDPFE
QRAREHGLHYVHLHGEVGVIGNGAGLVMSSLDAVSGAGEEQGSDVKPANFLDIGGGASAAVMAESLQIVLSDPQVESVFI
NIYGGITSCVEVANGILDAVAKLGGSKPIVVRFDGNAAAEGLHILASANKPNIHVSETMEDAAAKAAQLAGEAIQSKEVL

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI157779135, Length=386, Percent_Identity=32.1243523316062, Blast_Score=198, Evalue=8e-51,
Organism=Homo sapiens, GI294862256, Length=401, Percent_Identity=31.1720698254364, Blast_Score=195, Evalue=8e-50,
Organism=Homo sapiens, GI11321583, Length=390, Percent_Identity=32.3076923076923, Blast_Score=194, Evalue=1e-49,
Organism=Escherichia coli, GI1786948, Length=393, Percent_Identity=37.1501272264631, Blast_Score=223, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17567829, Length=404, Percent_Identity=32.9207920792079, Blast_Score=201, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17539378, Length=406, Percent_Identity=31.2807881773399, Blast_Score=198, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6321683, Length=405, Percent_Identity=32.8395061728395, Blast_Score=216, Evalue=5e-57,
Organism=Drosophila melanogaster, GI21356231, Length=403, Percent_Identity=32.5062034739454, Blast_Score=204, Evalue=8e-53,
Organism=Drosophila melanogaster, GI281361397, Length=389, Percent_Identity=32.9048843187661, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI281361395, Length=389, Percent_Identity=32.9048843187661, Blast_Score=195, Evalue=4e-50,
Organism=Drosophila melanogaster, GI161078106, Length=389, Percent_Identity=32.6478149100257, Blast_Score=194, Evalue=9e-50,
Organism=Drosophila melanogaster, GI24645208, Length=389, Percent_Identity=32.6478149100257, Blast_Score=194, Evalue=9e-50,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 42608; Mature: 42608

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLYEYQARQLLEEQDIPTPSAIFAQNSHEVAEAADAIGYPCVIKAQVKIGHRGQAGGVK
CCCHHHHHHHHHHHCCCCCCHHEEECCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEE
IAHNRDEAIVESESILPMTIHGHKVSGVLVAEAKNILHEYYVSISVDRTSRDFDVLATAN
EEECCCCHHEECCCEEEEEEECCEECEEEHHHHHHHHHHHEEEEEEECCCCCEEEEEECC
GGTEVEEIAKEHPESVKRLHIDALGDFDLAAATEMARSIGFYHADVDQAAQILLKMWRVF
CCCHHHHHHHHCHHHHHHEEHHCCCCCHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHH
KDNDATLVEINPLAKIGDPDDESTKQLSALDAKISLDDNAAFRHGGWERFVDSVVPDPFE
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHCEEEEECCCCCHHCCCHHHHHHHHCCCHHH
QRAREHGLHYVHLHGEVGVIGNGAGLVMSSLDAVSGAGEEQGSDVKPANFLDIGGGASAA
HHHHHCCCEEEEEECCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHH
VMAESLQIVLSDPQVESVFINIYGGITSCVEVANGILDAVAKLGGSKPIVVRFDGNAAAE
HHHHHHEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
GLHILASANKPNIHVSETMEDAAAKAAQLAGEAIQSKEVL
CEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDLYEYQARQLLEEQDIPTPSAIFAQNSHEVAEAADAIGYPCVIKAQVKIGHRGQAGGVK
CCCHHHHHHHHHHHCCCCCCHHEEECCCHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEE
IAHNRDEAIVESESILPMTIHGHKVSGVLVAEAKNILHEYYVSISVDRTSRDFDVLATAN
EEECCCCHHEECCCEEEEEEECCEECEEEHHHHHHHHHHHEEEEEEECCCCCEEEEEECC
GGTEVEEIAKEHPESVKRLHIDALGDFDLAAATEMARSIGFYHADVDQAAQILLKMWRVF
CCCHHHHHHHHCHHHHHHEEHHCCCCCHHHHHHHHHHHHCCEECCHHHHHHHHHHHHHHH
KDNDATLVEINPLAKIGDPDDESTKQLSALDAKISLDDNAAFRHGGWERFVDSVVPDPFE
CCCCCEEEEECCCCCCCCCCCHHHHHHHHHCEEEEECCCCCHHCCCHHHHHHHHCCCHHH
QRAREHGLHYVHLHGEVGVIGNGAGLVMSSLDAVSGAGEEQGSDVKPANFLDIGGGASAA
HHHHHCCCEEEEEECCEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCHHH
VMAESLQIVLSDPQVESVFINIYGGITSCVEVANGILDAVAKLGGSKPIVVRFDGNAAAE
HHHHHHEEEECCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCC
GLHILASANKPNIHVSETMEDAAAKAAQLAGEAIQSKEVL
CEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA