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The map label for this gene is apt

Identifier: 213692042

GI number: 213692042

Start: 1341261

End: 1341842

Strand: Direct

Name: apt

Synonym: Blon_1160

Alternate gene names: 213692042

Gene position: 1341261-1341842 (Clockwise)

Preceding gene: 213692041

Following gene: 213692043

Centisome position: 47.35

GC content: 64.09

Gene sequence:

>582_bases
ATGGCACAGTCGGACATCACCATCGACGCATTGGACAAGGTGGGACGGCAGGACGCCGAATATCTGGTGTCGTTGGTGCG
TTCCATACCCGGGTTCCCCAAGGAAGGCATCATCTTCCGTGATTTCATTCCGGTGTTCGCCGATCCCAAGGGCCTGAGAA
TCCTGCTCGAGGCGCTTGAGGCGGCCCTGCCGGTGCCCGCGAGCGAATTCGATTCCATCGCCGGCCTCGAGTCGCGCGGA
TTCCTGTTCGGCCCGGCTCTGGCCGCCCGCATGGGCAAGGGGTTCATCGCCGTACGCAAGGCCGGCAAGCTGCCGCCCGA
GACCATCGGCGAATCCTATGATCTCGAATACGGCTCGGCGCGCGTCGAAATCGAGACGGATGCCGTGCAGGCGGGGGAGC
GGGTACTTATCGTCGATGACCTCATCGCCACGGGCGGCACCGCCAAGGCCGCCACCGATCTTATCGACAAGGTGGGAGGC
ACCGTGGCGGGTTATGGTTTCGTGATGCGGCTCGAAGGCCTCGACGGCATCGACAAGCTTGGCGGCAAGCCCGTCAGCTC
GCTGATGGCGATGCCGGCCTGA

Upstream 100 bases:

>100_bases
CGAGGACATCGACTCCCCGGCCGCCGCAGACGGGACCGCCACGAAGTAGGCCGTACGATTTGGCGGCGTCGCAGCACATC
AGTACAGGAGGGTGAATATT

Downstream 100 bases:

>100_bases
GCGTTCGTCTCACCCAACATACATTCGGTTTTTAAGGTCCGTCATGTACTGTGTACAGTTACATGACGGACCAATTACAT
AGTCAGGGAAGGATCGATGG

Product: adenine phosphoribosyltransferase

Products: NA

Alternate protein names: APRT

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MAQSDITIDALDKVGRQDAEYLVSLVRSIPGFPKEGIIFRDFIPVFADPKGLRILLEALEAALPVPASEFDSIAGLESRG
FLFGPALAARMGKGFIAVRKAGKLPPETIGESYDLEYGSARVEIETDAVQAGERVLIVDDLIATGGTAKAATDLIDKVGG
TVAGYGFVMRLEGLDGIDKLGGKPVSSLMAMPA

Sequences:

>Translated_193_residues
MAQSDITIDALDKVGRQDAEYLVSLVRSIPGFPKEGIIFRDFIPVFADPKGLRILLEALEAALPVPASEFDSIAGLESRG
FLFGPALAARMGKGFIAVRKAGKLPPETIGESYDLEYGSARVEIETDAVQAGERVLIVDDLIATGGTAKAATDLIDKVGG
TVAGYGFVMRLEGLDGIDKLGGKPVSSLMAMPA
>Mature_192_residues
AQSDITIDALDKVGRQDAEYLVSLVRSIPGFPKEGIIFRDFIPVFADPKGLRILLEALEAALPVPASEFDSIAGLESRGF
LFGPALAARMGKGFIAVRKAGKLPPETIGESYDLEYGSARVEIETDAVQAGERVLIVDDLIATGGTAKAATDLIDKVGGT
VAGYGFVMRLEGLDGIDKLGGKPVSSLMAMPA

Specific function: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family

Homologues:

Organism=Homo sapiens, GI4502171, Length=165, Percent_Identity=45.4545454545455, Blast_Score=140, Evalue=6e-34,
Organism=Homo sapiens, GI71773201, Length=121, Percent_Identity=50.4132231404959, Blast_Score=121, Evalue=4e-28,
Organism=Escherichia coli, GI1786675, Length=176, Percent_Identity=43.1818181818182, Blast_Score=143, Evalue=9e-36,
Organism=Caenorhabditis elegans, GI17509087, Length=165, Percent_Identity=43.6363636363636, Blast_Score=137, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6323619, Length=166, Percent_Identity=47.5903614457831, Blast_Score=139, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6320649, Length=178, Percent_Identity=35.9550561797753, Blast_Score=100, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136334, Length=183, Percent_Identity=43.7158469945355, Blast_Score=132, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): APT_BIFLI (B7GR20)

Other databases:

- EMBL:   CP001095
- RefSeq:   YP_002322628.1
- ProteinModelPortal:   B7GR20
- GeneID:   7053326
- GenomeReviews:   CP001095_GR
- KEGG:   bln:Blon_1160
- HOGENOM:   HBG703830
- ProtClustDB:   PRK02304
- GO:   GO:0005737
- HAMAP:   MF_00004
- InterPro:   IPR005764
- InterPro:   IPR000836
- TIGRFAMs:   TIGR01090

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.7

Molecular weight: Translated: 20298; Mature: 20166

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSDITIDALDKVGRQDAEYLVSLVRSIPGFPKEGIIFRDFIPVFADPKGLRILLEALE
CCCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEHHHCHHHHCCCHHHHHHHHHHH
AALPVPASEFDSIAGLESRGFLFGPALAARMGKGFIAVRKAGKLPPETIGESYDLEYGSA
HHCCCCHHHHHHHCCCCCCCCEEHHHHHHHHCCCEEEEHHCCCCCHHHCCCCCCCCCCCE
RVEIETDAVQAGERVLIVDDLIATGGTAKAATDLIDKVGGTVAGYGFVMRLEGLDGIDKL
EEEEEHHHHHCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCEECCEEEEEECCCCCHHHH
GGKPVSSLMAMPA
CCCCHHHHHCCCC
>Mature Secondary Structure 
AQSDITIDALDKVGRQDAEYLVSLVRSIPGFPKEGIIFRDFIPVFADPKGLRILLEALE
CCCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEHHHCHHHHCCCHHHHHHHHHHH
AALPVPASEFDSIAGLESRGFLFGPALAARMGKGFIAVRKAGKLPPETIGESYDLEYGSA
HHCCCCHHHHHHHCCCCCCCCEEHHHHHHHHCCCEEEEHHCCCCCHHHCCCCCCCCCCCE
RVEIETDAVQAGERVLIVDDLIATGGTAKAATDLIDKVGGTVAGYGFVMRLEGLDGIDKL
EEEEEHHHHHCCCEEEEEEHHHHCCCCHHHHHHHHHHHCCCEECCEEEEEECCCCCHHHH
GGKPVSSLMAMPA
CCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA