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The map label for this gene is rbsK [H]

Identifier: 213691854

GI number: 213691854

Start: 1139692

End: 1140681

Strand: Direct

Name: rbsK [H]

Synonym: Blon_0963

Alternate gene names: 213691854

Gene position: 1139692-1140681 (Clockwise)

Preceding gene: 213691853

Following gene: 213691855

Centisome position: 40.23

GC content: 60.4

Gene sequence:

>990_bases
GTGATAAGTGAAGAAGAACATAAACAGATGCCCGAGCCCGTACGGGAACGATTGGAAGCGCTGAAGGATGCGCCGGGCTC
GGTAATCGTGGTCGGCTCGATGAACGCCGATTACACCGTGACCACCAAACGACTGCCCAAGCCAGGCGAAACCGTCAATG
GTGGTGCCATGAAAGTGCTGCCGGGCGGCAAAGGCGCGAATCAGGCGTCTGCCGCTGCTCGCCTCGGTGTCAATGTCCAG
TTGCTGGGCGCGGTGGGCGAGGACTCCAACGCGGACTTCCTATTAGGCAAGCTGGATGAGGCCGGCGTCGACACCGCCGA
TATCCTGCACGTTGAAGGCCCCAGCGGCACCACGGTAATCACCGTGAGCGCTGAGGGCGAGAACACCATCGTCTATTCGC
CGGGTTCCAATGCCAAGGCAAGTGCCAGCTATGTGCAATCACATCGCACGACCATCGCCGAATGCGCGGTATTGGGACTG
TGTTTGGAGAGCCCGATTTCCACCGTTATCGCCGCCGCGCAGACCGCGCATGACGCTGGCGTGACCGTGCTGCTCAACGA
CTCGCCATTTATGGACGAGCTTCCTCACGAACTGGTGGAAGCCACGGATATTCTTCTGGTCAACCAGCATGAAGCGGCTC
AACTGCTGGGTCTACCGGACGGCGATGTGGAATCACTCGACTGGTATGAGGTCGCCGAACGATTCACCGATTACGGATTC
GACCGGGCGATAGTGACGCTTGGTGCGTCGGGGGCGGTGGTGATCGAGAACGGACGTTGGCATCGCGTATCCGCCGCGCA
AGTCAATGCGGTGGACACCACCGGTTGCGGCGACTCGTTCATGGGAACTGTGCTGGCTGGCTTGGCCGCTGGCCATACGC
TGCTGCAATCCGCGCAAATCGGCTCCTATGTCTCCGCCTATGCGGCCACCAAGCTTGGTGCCCAAAGCGCCTACGGCACC
GCCGAAGAAGTCATCGCCTACTTCAGCTGA

Upstream 100 bases:

>100_bases
CTCTTGGTGCTGATGGTGGCCATGCACGAGCGTCTTCGTAAGTTGCGCGGCTGATCATGCGCGCATTTGGGCCCGCCGCC
TACTATGCTTGGAGCCCATG

Downstream 100 bases:

>100_bases
CCTATAATCGTACATATGTACGAAACCCTGAGCCTGTTTTCCGAACCCACCAAGGTGTGGTTCGAGCATGCCTTCGGTCA
GCCGACCGAGGCACAGGCTC

Product: PfkB domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MISEEEHKQMPEPVRERLEALKDAPGSVIVVGSMNADYTVTTKRLPKPGETVNGGAMKVLPGGKGANQASAAARLGVNVQ
LLGAVGEDSNADFLLGKLDEAGVDTADILHVEGPSGTTVITVSAEGENTIVYSPGSNAKASASYVQSHRTTIAECAVLGL
CLESPISTVIAAAQTAHDAGVTVLLNDSPFMDELPHELVEATDILLVNQHEAAQLLGLPDGDVESLDWYEVAERFTDYGF
DRAIVTLGASGAVVIENGRWHRVSAAQVNAVDTTGCGDSFMGTVLAGLAAGHTLLQSAQIGSYVSAYAATKLGAQSAYGT
AEEVIAYFS

Sequences:

>Translated_329_residues
MISEEEHKQMPEPVRERLEALKDAPGSVIVVGSMNADYTVTTKRLPKPGETVNGGAMKVLPGGKGANQASAAARLGVNVQ
LLGAVGEDSNADFLLGKLDEAGVDTADILHVEGPSGTTVITVSAEGENTIVYSPGSNAKASASYVQSHRTTIAECAVLGL
CLESPISTVIAAAQTAHDAGVTVLLNDSPFMDELPHELVEATDILLVNQHEAAQLLGLPDGDVESLDWYEVAERFTDYGF
DRAIVTLGASGAVVIENGRWHRVSAAQVNAVDTTGCGDSFMGTVLAGLAAGHTLLQSAQIGSYVSAYAATKLGAQSAYGT
AEEVIAYFS
>Mature_329_residues
MISEEEHKQMPEPVRERLEALKDAPGSVIVVGSMNADYTVTTKRLPKPGETVNGGAMKVLPGGKGANQASAAARLGVNVQ
LLGAVGEDSNADFLLGKLDEAGVDTADILHVEGPSGTTVITVSAEGENTIVYSPGSNAKASASYVQSHRTTIAECAVLGL
CLESPISTVIAAAQTAHDAGVTVLLNDSPFMDELPHELVEATDILLVNQHEAAQLLGLPDGDVESLDWYEVAERFTDYGF
DRAIVTLGASGAVVIENGRWHRVSAAQVNAVDTTGCGDSFMGTVLAGLAAGHTLLQSAQIGSYVSAYAATKLGAQSAYGT
AEEVIAYFS

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=292, Percent_Identity=32.1917808219178, Blast_Score=121, Evalue=8e-28,
Organism=Escherichia coli, GI1790193, Length=304, Percent_Identity=36.5131578947368, Blast_Score=171, Evalue=9e-44,
Organism=Escherichia coli, GI87082343, Length=269, Percent_Identity=27.5092936802974, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081971, Length=265, Percent_Identity=26.4150943396226, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=300, Percent_Identity=35, Blast_Score=155, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6319884, Length=320, Percent_Identity=28.125, Blast_Score=95, Evalue=1e-20,
Organism=Drosophila melanogaster, GI20128807, Length=270, Percent_Identity=35.1851851851852, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24583886, Length=303, Percent_Identity=31.023102310231, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 34129; Mature: 34129

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISEEEHKQMPEPVRERLEALKDAPGSVIVVGSMNADYTVTTKRLPKPGETVNGGAMKVL
CCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEE
PGGKGANQASAAARLGVNVQLLGAVGEDSNADFLLGKLDEAGVDTADILHVEGPSGTTVI
CCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCEEE
TVSAEGENTIVYSPGSNAKASASYVQSHRTTIAECAVLGLCLESPISTVIAAAQTAHDAG
EEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VTVLLNDSPFMDELPHELVEATDILLVNQHEAAQLLGLPDGDVESLDWYEVAERFTDYGF
EEEEECCCCCHHHHHHHHHHHHHEEEECCCCHHHEECCCCCCCCCCHHHHHHHHHHHCCC
DRAIVTLGASGAVVIENGRWHRVSAAQVNAVDTTGCGDSFMGTVLAGLAAGHTLLQSAQI
CEEEEEECCCCEEEEECCCEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GSYVSAYAATKLGAQSAYGTAEEVIAYFS
HHHHHHHHHHHHCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MISEEEHKQMPEPVRERLEALKDAPGSVIVVGSMNADYTVTTKRLPKPGETVNGGAMKVL
CCCCHHHHCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCEEEEE
PGGKGANQASAAARLGVNVQLLGAVGEDSNADFLLGKLDEAGVDTADILHVEGPSGTTVI
CCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCEEE
TVSAEGENTIVYSPGSNAKASASYVQSHRTTIAECAVLGLCLESPISTVIAAAQTAHDAG
EEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VTVLLNDSPFMDELPHELVEATDILLVNQHEAAQLLGLPDGDVESLDWYEVAERFTDYGF
EEEEECCCCCHHHHHHHHHHHHHEEEECCCCHHHEECCCCCCCCCCHHHHHHHHHHHCCC
DRAIVTLGASGAVVIENGRWHRVSAAQVNAVDTTGCGDSFMGTVLAGLAAGHTLLQSAQI
CEEEEEECCCCEEEEECCCEEEEECCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
GSYVSAYAATKLGAQSAYGTAEEVIAYFS
HHHHHHHHHHHHCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]