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The map label for this gene is celR [H]

Identifier: 213691766

GI number: 213691766

Start: 1031960

End: 1033081

Strand: Direct

Name: celR [H]

Synonym: Blon_0874

Alternate gene names: 213691766

Gene position: 1031960-1033081 (Clockwise)

Preceding gene: 213691765

Following gene: 213691771

Centisome position: 36.43

GC content: 63.28

Gene sequence:

>1122_bases
ATGGGACCTGCTCGCGGGGCGTCATCGCCGGCGTCTACAGGTGCGCAGCGTGTGAGCTTGAAGGACATCGCGGACGAGCT
GGGCATTTCGCAGACCGCGGTGTCCTTTGCCATCAACGACCGGCCCGGCGTCTCCGAGCAGACCAGGCGGCGGGTCAAAC
AGGTCGCGGCGGAACTCGGATGGACGCCGGTCTACGCCGCGCAGGCGTTGGGTTCATCGAGAACCATGACCATAGGCTTC
GCGCCCGCGCGATCCGTGCAGGGACTCACCGATGAAACCTTCATGTTGCATTTCATGGCCGGCGTGCATACCTCGCTCAG
TCCCAAGGGATACGGTCTATTGTACCGACCATGCCGATCGTTGAACGAGGAGATGAGCGTCTATCGGGGCTGGGCGTCGA
GCAAGCGCGTGGATGGCGTGATTCTGGTCGACCTGCGGGCCGATGATCCGCGGCCCGCGCTGTTGAGGGAGTTGGGGGTC
CGCGCGGTGTTGGCGGGCGGACCCGATCCGAATGATTACGTTCCCTCCCTGTCCATCGATGATTCGCGCACCATGGGCAC
CGTGCTCGAACATCTGTCGTCGTTGGGGCATCGCCGGATCGCCTACCTTTCCGGCGACGCCAATCTGGATTATTCCCAGG
GGCGTGTGGCGGCGTTCCGCTCGTTCGCCAAGAGACGCAGACTGGAGTCCATCGCCATCGAGTTCACGAATTTCGCCGCC
GAACGGGCCGTGACGCTGACGATGGGGATGTTGCGCTCGCCGCAGCCGCCCACCGCGTTCATCTATGAGACGGAGATTCT
TGCGGCGGCGAGTCTGCATGCCATGGCCAAAGCCTATGCCACCTGTGCCGCCACCATTGGGCGATTGGCGTCGGGGGAGG
GGCGGTTCGCGGCATATCCCAGCGGATTGCCCGCCATCGTCAGTTTCGAGGACAGCTTCATCTGCGAGACGGCGTATCCG
TCGATCACTTCGGTGCACCGCGATGCCGGCGAATACGGCGTCAAAGTGGCGAGGCTGTTGCTCAAGGTGCTTGCCGGCGA
GCAGGTGGGTGGCAATAGGCGGATTCTCACCCCGAAACTGGTGGTCAGAGACAGTACGTCCGAACCAGTGGATCCGTCAT
GA

Upstream 100 bases:

>100_bases
GCTTCGGACATCCGGCGCGACAATCGGGGTGTGGTGCGCGGCGGGAAGCATAATGTGTTGTAGCGTGGTATTCGCATCGT
GGCTGCAAGGAGGAGTATTC

Downstream 100 bases:

>100_bases
CGCGGGCGGGGCGCATCACGGGACGATGTGCCGTGATGCGCCCCGCCCGCGTCAGCGATTGCCGGCGTGAGGACGCCACG
GCGATGGTCACGCCGCGTTT

Product: regulatory protein, LacI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MGPARGASSPASTGAQRVSLKDIADELGISQTAVSFAINDRPGVSEQTRRRVKQVAAELGWTPVYAAQALGSSRTMTIGF
APARSVQGLTDETFMLHFMAGVHTSLSPKGYGLLYRPCRSLNEEMSVYRGWASSKRVDGVILVDLRADDPRPALLRELGV
RAVLAGGPDPNDYVPSLSIDDSRTMGTVLEHLSSLGHRRIAYLSGDANLDYSQGRVAAFRSFAKRRRLESIAIEFTNFAA
ERAVTLTMGMLRSPQPPTAFIYETEILAAASLHAMAKAYATCAATIGRLASGEGRFAAYPSGLPAIVSFEDSFICETAYP
SITSVHRDAGEYGVKVARLLLKVLAGEQVGGNRRILTPKLVVRDSTSEPVDPS

Sequences:

>Translated_373_residues
MGPARGASSPASTGAQRVSLKDIADELGISQTAVSFAINDRPGVSEQTRRRVKQVAAELGWTPVYAAQALGSSRTMTIGF
APARSVQGLTDETFMLHFMAGVHTSLSPKGYGLLYRPCRSLNEEMSVYRGWASSKRVDGVILVDLRADDPRPALLRELGV
RAVLAGGPDPNDYVPSLSIDDSRTMGTVLEHLSSLGHRRIAYLSGDANLDYSQGRVAAFRSFAKRRRLESIAIEFTNFAA
ERAVTLTMGMLRSPQPPTAFIYETEILAAASLHAMAKAYATCAATIGRLASGEGRFAAYPSGLPAIVSFEDSFICETAYP
SITSVHRDAGEYGVKVARLLLKVLAGEQVGGNRRILTPKLVVRDSTSEPVDPS
>Mature_372_residues
GPARGASSPASTGAQRVSLKDIADELGISQTAVSFAINDRPGVSEQTRRRVKQVAAELGWTPVYAAQALGSSRTMTIGFA
PARSVQGLTDETFMLHFMAGVHTSLSPKGYGLLYRPCRSLNEEMSVYRGWASSKRVDGVILVDLRADDPRPALLRELGVR
AVLAGGPDPNDYVPSLSIDDSRTMGTVLEHLSSLGHRRIAYLSGDANLDYSQGRVAAFRSFAKRRRLESIAIEFTNFAAE
RAVTLTMGMLRSPQPPTAFIYETEILAAASLHAMAKAYATCAATIGRLASGEGRFAAYPSGLPAIVSFEDSFICETAYPS
ITSVHRDAGEYGVKVARLLLKVLAGEQVGGNRRILTPKLVVRDSTSEPVDPS

Specific function: Binds to the 14-bp operator sequence 5'-TGGGAGCGCTCCCA- 3' in the upstream regions of cellulase genes; these operator sequences are modulated by cellobiose [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=355, Percent_Identity=24.7887323943662, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1786540, Length=359, Percent_Identity=26.4623955431755, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1790194, Length=352, Percent_Identity=23.8636363636364, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787948, Length=356, Percent_Identity=22.752808988764, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 40054; Mature: 39923

Theoretical pI: Translated: 9.23; Mature: 9.23

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPARGASSPASTGAQRVSLKDIADELGISQTAVSFAINDRPGVSEQTRRRVKQVAAELG
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHC
WTPVYAAQALGSSRTMTIGFAPARSVQGLTDETFMLHFMAGVHTSLSPKGYGLLYRPCRS
CCHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LNEEMSVYRGWASSKRVDGVILVDLRADDPRPALLRELGVRAVLAGGPDPNDYVPSLSID
HHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCC
DSRTMGTVLEHLSSLGHRRIAYLSGDANLDYSQGRVAAFRSFAKRRRLESIAIEFTNFAA
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAVTLTMGMLRSPQPPTAFIYETEILAAASLHAMAKAYATCAATIGRLASGEGRFAAYP
HHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECC
SGLPAIVSFEDSFICETAYPSITSVHRDAGEYGVKVARLLLKVLAGEQVGGNRRILTPKL
CCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCEE
VVRDSTSEPVDPS
EEECCCCCCCCCC
>Mature Secondary Structure 
GPARGASSPASTGAQRVSLKDIADELGISQTAVSFAINDRPGVSEQTRRRVKQVAAELG
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHC
WTPVYAAQALGSSRTMTIGFAPARSVQGLTDETFMLHFMAGVHTSLSPKGYGLLYRPCRS
CCHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHH
LNEEMSVYRGWASSKRVDGVILVDLRADDPRPALLRELGVRAVLAGGPDPNDYVPSLSID
HHHHHHHHHCCCCCCCCCEEEEEEEECCCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCC
DSRTMGTVLEHLSSLGHRRIAYLSGDANLDYSQGRVAAFRSFAKRRRLESIAIEFTNFAA
CCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAVTLTMGMLRSPQPPTAFIYETEILAAASLHAMAKAYATCAATIGRLASGEGRFAAYP
HHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECC
SGLPAIVSFEDSFICETAYPSITSVHRDAGEYGVKVARLLLKVLAGEQVGGNRRILTPKL
CCCCEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCEE
VVRDSTSEPVDPS
EEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10224066 [H]