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The map label for this gene is czcD [H]

Identifier: 213691735

GI number: 213691735

Start: 992556

End: 993494

Strand: Reverse

Name: czcD [H]

Synonym: Blon_0841

Alternate gene names: 213691735

Gene position: 993494-992556 (Counterclockwise)

Preceding gene: 213691736

Following gene: 213691732

Centisome position: 35.07

GC content: 59.32

Gene sequence:

>939_bases
ATGGCTCATACCCATGCACCCGCATCATCCACATCCGTAGACCCTGCCGCGCATCAGCGCAGGCTGATTGCCACGTTGAC
CGTCACCGGTTCGGTCTTCCTCATCGAAGTGGTGTCGGCCGTTTTAACCGGCTCACTGGCCCTGCTGGTGGATGCCGGTC
ATATGCTCACCGACATGTCCGTGCTGGTGGCATCCACAATCACCGCCATACTGATGCGCCGCAAGCCCAACAACACTCGT
ACTTGGGGCTGGGCCAGGCTTGAGGTGCTCACCGCTGCCGCAGGTGCCGTGGTGCTGCTCGTCGTTGGCATCTATGCGTT
GGTGGAGGCCGGCATGCGTCTGTTCGGCGGTTCCAAAGCGGAAATCGACGATATCGGCTTGCTGCTGTTCGTGGGCATTC
TGGGTCTTGCCGCAAATATCATCTCGATTTTCATCCTTGCCTCGCAGCGCGAAGACAACATGAATATGAAGGCCGCGTTC
CTCGAGGTGATGAATGACGCACTTGGCTCGGTGGCCGTGGTGGCCTCTGCCCTGGTAATGATCTCCACCGGATGGAATGG
CTTCGACGCCGTGGCCGGTGCCGTCATCGCACTGATGATGATTCCGCGCGCCATCAAGTTGCTGCACAACGCGGTCAAGG
TGCTGCTGGAGGAAACGCCGGATGGACTTGACCTCGATAAGGTACGCGAACATCTGGAAAGCATGCCGCATGTGCTTGCC
GTGCATGACCTCCACGCCAGCACGGTGTCCACCGGCATGCCGATTCTGATGGCCCACGTGGTAGTTGACAAAGACCTCAC
CATGGAAGATGCCGCCACAATCCTCACCCAACTGCAGGATTGCCTGCGCGAGCACTTCCCGGTCTCGATCCCCCACACCA
CCTTCCAGCTCGAGCCCGAGGGCTATAGCTCCCACTCCCCCAACGAATTCCACGAATAA

Upstream 100 bases:

>100_bases
TTACGAAACCCCGGCCTCGCGCCGGGGTTTCGTCGTATTCAGACCATATCGCAAATGGTATTGAGAAGCGGTTTCAACTC
GATAGAGCGAAGGAGTACAT

Downstream 100 bases:

>100_bases
AAAAATGCTCTCAACGGGAGCATTCAGCAGGGTATAGAAAATCGCTGCACATGCGCGACCTTCGTGCCGCACAAAGTGAA
GGCCTACAAAATAGGTCGAG

Product: cation diffusion facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MAHTHAPASSTSVDPAAHQRRLIATLTVTGSVFLIEVVSAVLTGSLALLVDAGHMLTDMSVLVASTITAILMRRKPNNTR
TWGWARLEVLTAAAGAVVLLVVGIYALVEAGMRLFGGSKAEIDDIGLLLFVGILGLAANIISIFILASQREDNMNMKAAF
LEVMNDALGSVAVVASALVMISTGWNGFDAVAGAVIALMMIPRAIKLLHNAVKVLLEETPDGLDLDKVREHLESMPHVLA
VHDLHASTVSTGMPILMAHVVVDKDLTMEDAATILTQLQDCLREHFPVSIPHTTFQLEPEGYSSHSPNEFHE

Sequences:

>Translated_312_residues
MAHTHAPASSTSVDPAAHQRRLIATLTVTGSVFLIEVVSAVLTGSLALLVDAGHMLTDMSVLVASTITAILMRRKPNNTR
TWGWARLEVLTAAAGAVVLLVVGIYALVEAGMRLFGGSKAEIDDIGLLLFVGILGLAANIISIFILASQREDNMNMKAAF
LEVMNDALGSVAVVASALVMISTGWNGFDAVAGAVIALMMIPRAIKLLHNAVKVLLEETPDGLDLDKVREHLESMPHVLA
VHDLHASTVSTGMPILMAHVVVDKDLTMEDAATILTQLQDCLREHFPVSIPHTTFQLEPEGYSSHSPNEFHE
>Mature_311_residues
AHTHAPASSTSVDPAAHQRRLIATLTVTGSVFLIEVVSAVLTGSLALLVDAGHMLTDMSVLVASTITAILMRRKPNNTRT
WGWARLEVLTAAAGAVVLLVVGIYALVEAGMRLFGGSKAEIDDIGLLLFVGILGLAANIISIFILASQREDNMNMKAAFL
EVMNDALGSVAVVASALVMISTGWNGFDAVAGAVIALMMIPRAIKLLHNAVKVLLEETPDGLDLDKVREHLESMPHVLAV
HDLHASTVSTGMPILMAHVVVDKDLTMEDAATILTQLQDCLREHFPVSIPHTTFQLEPEGYSSHSPNEFHE

Specific function: Necessary for activation of the czc determinant [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=315, Percent_Identity=29.2063492063492, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI21361112, Length=307, Percent_Identity=27.6872964169381, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI21359890, Length=273, Percent_Identity=25.2747252747253, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI64762489, Length=274, Percent_Identity=25.9124087591241, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI289803013, Length=274, Percent_Identity=25.9124087591241, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI289803009, Length=274, Percent_Identity=25.9124087591241, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI289803007, Length=274, Percent_Identity=25.9124087591241, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI289803003, Length=274, Percent_Identity=25.9124087591241, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI52351208, Length=128, Percent_Identity=37.5, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI14210520, Length=228, Percent_Identity=28.5087719298246, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1786966, Length=291, Percent_Identity=35.7388316151203, Blast_Score=140, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI193210990, Length=321, Percent_Identity=28.0373831775701, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI32564488, Length=310, Percent_Identity=25.8064516129032, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17555796, Length=313, Percent_Identity=26.1980830670927, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17555794, Length=284, Percent_Identity=27.4647887323944, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323899, Length=136, Percent_Identity=34.5588235294118, Blast_Score=82, Evalue=9e-17,
Organism=Saccharomyces cerevisiae, GI6324892, Length=138, Percent_Identity=31.8840579710145, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583858, Length=343, Percent_Identity=27.6967930029155, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24656728, Length=304, Percent_Identity=27.9605263157895, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24656724, Length=304, Percent_Identity=27.9605263157895, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24656720, Length=304, Percent_Identity=27.9605263157895, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24656715, Length=304, Percent_Identity=27.9605263157895, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357035, Length=304, Percent_Identity=27.9605263157895, Blast_Score=91, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 33346; Mature: 33215

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHTHAPASSTSVDPAAHQRRLIATLTVTGSVFLIEVVSAVLTGSLALLVDAGHMLTDMS
CCCCCCCCCCCCCCHHHHHHHEEEEEEECCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHH
VLVASTITAILMRRKPNNTRTWGWARLEVLTAAAGAVVLLVVGIYALVEAGMRLFGGSKA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EIDDIGLLLFVGILGLAANIISIFILASQREDNMNMKAAFLEVMNDALGSVAVVASALVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISTGWNGFDAVAGAVIALMMIPRAIKLLHNAVKVLLEETPDGLDLDKVREHLESMPHVLA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEE
VHDLHASTVSTGMPILMAHVVVDKDLTMEDAATILTQLQDCLREHFPVSIPHTTFQLEPE
HHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
GYSSHSPNEFHE
CCCCCCCCCCCC
>Mature Secondary Structure 
AHTHAPASSTSVDPAAHQRRLIATLTVTGSVFLIEVVSAVLTGSLALLVDAGHMLTDMS
CCCCCCCCCCCCCHHHHHHHEEEEEEECCHHHHHHHHHHHHHCCHHHHHCCCHHHHHHH
VLVASTITAILMRRKPNNTRTWGWARLEVLTAAAGAVVLLVVGIYALVEAGMRLFGGSKA
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
EIDDIGLLLFVGILGLAANIISIFILASQREDNMNMKAAFLEVMNDALGSVAVVASALVM
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ISTGWNGFDAVAGAVIALMMIPRAIKLLHNAVKVLLEETPDGLDLDKVREHLESMPHVLA
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEE
VHDLHASTVSTGMPILMAHVVVDKDLTMEDAATILTQLQDCLREHFPVSIPHTTFQLEPE
HHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCC
GYSSHSPNEFHE
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]