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The map label for this gene is hisC [H]

Identifier: 213691719

GI number: 213691719

Start: 970951

End: 972111

Strand: Direct

Name: hisC [H]

Synonym: Blon_0824

Alternate gene names: 213691719

Gene position: 970951-972111 (Clockwise)

Preceding gene: 213691718

Following gene: 213691720

Centisome position: 34.28

GC content: 63.57

Gene sequence:

>1161_bases
ATGAGCTCGATTCCCGCAAACCTGCCGTTGCGCAACGACCTGATCGGTGAGGAGCCGTACGGCGCTCCCCAGCTGGACGT
GCCGGTGTGCCTGAACGTCAACGAGAACCCGTATGCGCCGGACCCGGCCGTATGCGACACCATCGCCAAGCGTGTGCGTG
AAATCGCCCCCACACTCAACCGATACCCGGACCGTGAGCACATCGAATTGCGTCAGGCATTCTCCGATTACCTGGCCCGC
GAATCCGGTACCCGTCTGGACGTGGACGAGCTGTGGGGCGCGAACGGCTCCAACGAGATCATGCTCCAGCTGTTCCAGGC
TTTCGGCGGCCCGGGCCGCACCGCACTCGGTGCCGACCCGACGTACTCCATGTACCCGGAGTACGCCCGCGACACCTTCA
CCGGTTGGAAGCTCGCCCACCGCAACGCCGACTTCACGCTGAACGTCGACAAGGTGCTTGAGGCCATCGCCGAGGTCAAG
CCCTCGATGGTGCTGCTCACCAGACCAAACAACCCGACTGGCACCCCGTTGCCGATGGAGGATATCGAGTGTATTCTCGC
CGCCTGCGAAACCGCTGAAGTGGCCGGCGCGGGCGAGGGCGTGCACCCGATTCTCGTCATCGACGAAGCGTACGTGGAAT
TCCGCAAGCCAGGCACCCCGAGCGCCGTGAGCCTGATCAAGGACCACCCGAACTTGGCCGTCAGCCGCACCATGAGCAAG
GCCTTTGCCTTCGCCGGAGCGCGAGTCGGCTACCTAGCCGCATCCAAGGGCATCATCGACTGCGTGCGCATCGTACGCAT
GCCGTACCACCTGTCCGCCGTGACCCAGGCCGCCGCACTGGCTGCCTTCGAACACACCGATGAACAGCTGAGCCGTGTCG
AGCACCTGCGCGAAACCCGCGAGGCCACCGCCGCATGGCTCAAGGAACAGACCTACAAGGACCAGCCGCTTGAAGTGGCC
GAATCCGGCTCGAACTTCCTTCTGTTCGGTGGGCACTTCGACAAGCGCGAAGCCATCTTCGACGAGCTCCTGAAGCGCGG
CGTACTCATCCGCGTGGTCGGACCGGACGGTTGGCTGCGCGTGTGCATGGGCACCGACGAGGAGATGGAGACCTTCCGTA
ACGCCCTTGTTGAAGTGCTTCGTATAGTGGAAGCAGCATAA

Upstream 100 bases:

>100_bases
AGGATCTGCCCGCCCACGGCGAGTGCGTGCTCTCCCGCTTCGTCAAGGATCCGTATGACAAGGCCACCCTGCGCGAGCAG
GAGAAGGGAGCCGGTCTGCG

Downstream 100 bases:

>100_bases
GGGACGTTTCTTTCCGATTGCGGCGAGACCCGAAGCGATTCGAGTCCCGCCGCAATCCAATATGACGAATCACACAGGAG
ACATGATGGCAAGAACCGCG

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSSIPANLPLRNDLIGEEPYGAPQLDVPVCLNVNENPYAPDPAVCDTIAKRVREIAPTLNRYPDREHIELRQAFSDYLAR
ESGTRLDVDELWGANGSNEIMLQLFQAFGGPGRTALGADPTYSMYPEYARDTFTGWKLAHRNADFTLNVDKVLEAIAEVK
PSMVLLTRPNNPTGTPLPMEDIECILAACETAEVAGAGEGVHPILVIDEAYVEFRKPGTPSAVSLIKDHPNLAVSRTMSK
AFAFAGARVGYLAASKGIIDCVRIVRMPYHLSAVTQAAALAAFEHTDEQLSRVEHLRETREATAAWLKEQTYKDQPLEVA
ESGSNFLLFGGHFDKREAIFDELLKRGVLIRVVGPDGWLRVCMGTDEEMETFRNALVEVLRIVEAA

Sequences:

>Translated_386_residues
MSSIPANLPLRNDLIGEEPYGAPQLDVPVCLNVNENPYAPDPAVCDTIAKRVREIAPTLNRYPDREHIELRQAFSDYLAR
ESGTRLDVDELWGANGSNEIMLQLFQAFGGPGRTALGADPTYSMYPEYARDTFTGWKLAHRNADFTLNVDKVLEAIAEVK
PSMVLLTRPNNPTGTPLPMEDIECILAACETAEVAGAGEGVHPILVIDEAYVEFRKPGTPSAVSLIKDHPNLAVSRTMSK
AFAFAGARVGYLAASKGIIDCVRIVRMPYHLSAVTQAAALAAFEHTDEQLSRVEHLRETREATAAWLKEQTYKDQPLEVA
ESGSNFLLFGGHFDKREAIFDELLKRGVLIRVVGPDGWLRVCMGTDEEMETFRNALVEVLRIVEAA
>Mature_385_residues
SSIPANLPLRNDLIGEEPYGAPQLDVPVCLNVNENPYAPDPAVCDTIAKRVREIAPTLNRYPDREHIELRQAFSDYLARE
SGTRLDVDELWGANGSNEIMLQLFQAFGGPGRTALGADPTYSMYPEYARDTFTGWKLAHRNADFTLNVDKVLEAIAEVKP
SMVLLTRPNNPTGTPLPMEDIECILAACETAEVAGAGEGVHPILVIDEAYVEFRKPGTPSAVSLIKDHPNLAVSRTMSKA
FAFAGARVGYLAASKGIIDCVRIVRMPYHLSAVTQAAALAAFEHTDEQLSRVEHLRETREATAAWLKEQTYKDQPLEVAE
SGSNFLLFGGHFDKREAIFDELLKRGVLIRVVGPDGWLRVCMGTDEEMETFRNALVEVLRIVEAA

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=357, Percent_Identity=28.8515406162465, Blast_Score=108, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6322075, Length=389, Percent_Identity=26.7352185089974, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 42554; Mature: 42423

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIPANLPLRNDLIGEEPYGAPQLDVPVCLNVNENPYAPDPAVCDTIAKRVREIAPTLN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
RYPDREHIELRQAFSDYLARESGTRLDVDELWGANGSNEIMLQLFQAFGGPGRTALGADP
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCC
TYSMYPEYARDTFTGWKLAHRNADFTLNVDKVLEAIAEVKPSMVLLTRPNNPTGTPLPME
CHHCCCHHHHHCCCCCEEEECCCCEEEEHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHH
DIECILAACETAEVAGAGEGVHPILVIDEAYVEFRKPGTPSAVSLIKDHPNLAVSRTMSK
HHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHH
AFAFAGARVGYLAASKGIIDCVRIVRMPYHLSAVTQAAALAAFEHTDEQLSRVEHLRETR
HHHHHCCHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EATAAWLKEQTYKDQPLEVAESGSNFLLFGGHFDKREAIFDELLKRGVLIRVVGPDGWLR
HHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCEEE
VCMGTDEEMETFRNALVEVLRIVEAA
EECCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSIPANLPLRNDLIGEEPYGAPQLDVPVCLNVNENPYAPDPAVCDTIAKRVREIAPTLN
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
RYPDREHIELRQAFSDYLARESGTRLDVDELWGANGSNEIMLQLFQAFGGPGRTALGADP
CCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCC
TYSMYPEYARDTFTGWKLAHRNADFTLNVDKVLEAIAEVKPSMVLLTRPNNPTGTPLPME
CHHCCCHHHHHCCCCCEEEECCCCEEEEHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHH
DIECILAACETAEVAGAGEGVHPILVIDEAYVEFRKPGTPSAVSLIKDHPNLAVSRTMSK
HHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHCCCCCCHHHHHHHCCCCHHHHHHHHH
AFAFAGARVGYLAASKGIIDCVRIVRMPYHLSAVTQAAALAAFEHTDEQLSRVEHLRETR
HHHHHCCHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EATAAWLKEQTYKDQPLEVAESGSNFLLFGGHFDKREAIFDELLKRGVLIRVVGPDGWLR
HHHHHHHHHHHCCCCCHHHHHCCCCEEEECCCCCHHHHHHHHHHHCCEEEEEECCCCEEE
VCMGTDEEMETFRNALVEVLRIVEAA
EECCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]