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The map label for this gene is thiM [H]

Identifier: 213691692

GI number: 213691692

Start: 924932

End: 925876

Strand: Reverse

Name: thiM [H]

Synonym: Blon_0797

Alternate gene names: 213691692

Gene position: 925876-924932 (Counterclockwise)

Preceding gene: 213691702

Following gene: 213691691

Centisome position: 32.68

GC content: 62.75

Gene sequence:

>945_bases
ATGAGCAATAGTGCATCATCGTTTGCCGATGTGTCCAGCGGTTGTACCGCCGGGACTCCGGTTCCAGCCGATTCACCCAT
CCGCGATAATATCGCCGATGCCGTTCGCCGCGTACGCGAGACGACTCCATTGGCCCAGTCATTCACCAATTTTGTGACCA
TCAATTTGGTTGCCAACGCGCAACTGGCGGCCGGCGGCACTGCGGCCATGAGTTTCCTGCCGGACGACGTGATCGAAACC
GCGAAAATCGCGGGCGCGAACTACATCAACGTGGGCACGCTGCTGCCGTTCTATAAGGATGCGCTGCCCGAAATCGCCCA
GCGACTCAACTACTTGGACAAGCCGTGGGTGCTCGACCCGGTGGCCGCCGGCATCGGCCACACCCGCACCGCCATTCTTC
AGACCTTCAAGGCCGCTCCCCCGACCATGATTCGCGCGAACGCCTCCGAGGTAATCGCGCTGGCGAACATGTGGGGGCTC
AATACCGAAACCGTGGGGGACGCTTCCGAGCACCGCCCCGCCGGAGTGGAATCCGTCGACGACGTGGAGTCCGCAACCGG
TGCGGCGGTGGCGCTGGCACAGTATCTGACCGAACAGCACGCCAAGCATTCCTCCCATGACGCTTCCACCCGCTGTGCAG
TGGCTGTGTCCGGCATCGCCGATCTGGTGACCGACGGCGAAACCGTGTACCGACTGCCGGGCGGCAGCGCGATGATGACC
AAGATCACCGGTGCAGGCTGCTCGCTGGGCGGCGTGGCTGCCACATATCTGGCGGTTTCCGATCCGTTGACCGCCGCTCT
GTCCGCATCTCTGCTGTACAACCGCGCGGCAGAGATAGCCGATACGACTTCGCACGGGCCGGGCTCGTTCCAGGTCGCGT
TCCTTGACGCGCTGTGGAATGTTACCGCCGAACAGGTGGCGGAATCCGAGATTTTGGTGCAGTAG

Upstream 100 bases:

>100_bases
CACTGTAGTGCAGGGGGACTCGCATGTGGTTCGCGAGTTGAGAAAGGCCTGAGCCTGACCCTTAGAACCTGTTGGTTAAG
ACCATCGTAGGGAGCAGTAA

Downstream 100 bases:

>100_bases
TTTCAGTTCCCTCTGATGAGGGAGCTCATAACAGTTTTTCCCAATAAGACTTCCACAAGAAACAACAAAGGTAGGAATAA
TAATGAGTAATGAATACCCA

Product: Hydroxyethylthiazole kinase

Products: NA

Alternate protein names: 4-methyl-5-beta-hydroxyethylthiazole kinase; TH kinase; Thz kinase [H]

Number of amino acids: Translated: 314; Mature: 313

Protein sequence:

>314_residues
MSNSASSFADVSSGCTAGTPVPADSPIRDNIADAVRRVRETTPLAQSFTNFVTINLVANAQLAAGGTAAMSFLPDDVIET
AKIAGANYINVGTLLPFYKDALPEIAQRLNYLDKPWVLDPVAAGIGHTRTAILQTFKAAPPTMIRANASEVIALANMWGL
NTETVGDASEHRPAGVESVDDVESATGAAVALAQYLTEQHAKHSSHDASTRCAVAVSGIADLVTDGETVYRLPGGSAMMT
KITGAGCSLGGVAATYLAVSDPLTAALSASLLYNRAAEIADTTSHGPGSFQVAFLDALWNVTAEQVAESEILVQ

Sequences:

>Translated_314_residues
MSNSASSFADVSSGCTAGTPVPADSPIRDNIADAVRRVRETTPLAQSFTNFVTINLVANAQLAAGGTAAMSFLPDDVIET
AKIAGANYINVGTLLPFYKDALPEIAQRLNYLDKPWVLDPVAAGIGHTRTAILQTFKAAPPTMIRANASEVIALANMWGL
NTETVGDASEHRPAGVESVDDVESATGAAVALAQYLTEQHAKHSSHDASTRCAVAVSGIADLVTDGETVYRLPGGSAMMT
KITGAGCSLGGVAATYLAVSDPLTAALSASLLYNRAAEIADTTSHGPGSFQVAFLDALWNVTAEQVAESEILVQ
>Mature_313_residues
SNSASSFADVSSGCTAGTPVPADSPIRDNIADAVRRVRETTPLAQSFTNFVTINLVANAQLAAGGTAAMSFLPDDVIETA
KIAGANYINVGTLLPFYKDALPEIAQRLNYLDKPWVLDPVAAGIGHTRTAILQTFKAAPPTMIRANASEVIALANMWGLN
TETVGDASEHRPAGVESVDDVESATGAAVALAQYLTEQHAKHSSHDASTRCAVAVSGIADLVTDGETVYRLPGGSAMMTK
ITGAGCSLGGVAATYLAVSDPLTAALSASLLYNRAAEIADTTSHGPGSFQVAFLDALWNVTAEQVAESEILVQ

Specific function: Thiamine biosynthesis. [C]

COG id: COG2145

COG function: function code H; Hydroxyethylthiazole kinase, sugar kinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Thz kinase family [H]

Homologues:

Organism=Escherichia coli, GI1788421, Length=274, Percent_Identity=35.4014598540146, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6325042, Length=310, Percent_Identity=27.0967741935484, Blast_Score=91, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000417 [H]

Pfam domain/function: PF02110 HK [H]

EC number: =2.7.1.50 [H]

Molecular weight: Translated: 32493; Mature: 32361

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSASSFADVSSGCTAGTPVPADSPIRDNIADAVRRVRETTPLAQSFTNFVTINLVANA
CCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHEEEEEEEECC
QLAAGGTAAMSFLPDDVIETAKIAGANYINVGTLLPFYKDALPEIAQRLNYLDKPWVLDP
EECCCCHHHHHHCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEECH
VAAGIGHTRTAILQTFKAAPPTMIRANASEVIALANMWGLNTETVGDASEHRPAGVESVD
HHHCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHH
DVESATGAAVALAQYLTEQHAKHSSHDASTRCAVAVSGIADLVTDGETVYRLPGGSAMMT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEE
KITGAGCSLGGVAATYLAVSDPLTAALSASLLYNRAAEIADTTSHGPGSFQVAFLDALWN
EECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHH
VTAEQVAESEILVQ
HHHHHHHHHHHCCC
>Mature Secondary Structure 
SNSASSFADVSSGCTAGTPVPADSPIRDNIADAVRRVRETTPLAQSFTNFVTINLVANA
CCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHEEEEEEEECC
QLAAGGTAAMSFLPDDVIETAKIAGANYINVGTLLPFYKDALPEIAQRLNYLDKPWVLDP
EECCCCHHHHHHCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEECH
VAAGIGHTRTAILQTFKAAPPTMIRANASEVIALANMWGLNTETVGDASEHRPAGVESVD
HHHCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHH
DVESATGAAVALAQYLTEQHAKHSSHDASTRCAVAVSGIADLVTDGETVYRLPGGSAMMT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCCEEEE
KITGAGCSLGGVAATYLAVSDPLTAALSASLLYNRAAEIADTTSHGPGSFQVAFLDALWN
EECCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHH
VTAEQVAESEILVQ
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA