Click here to switch to the map view.

The map label for this gene is tcyB [H]

Identifier: 213691657

GI number: 213691657

Start: 883405

End: 884067

Strand: Direct

Name: tcyB [H]

Synonym: Blon_0761

Alternate gene names: 213691657

Gene position: 883405-884067 (Clockwise)

Preceding gene: 213691656

Following gene: 213691658

Centisome position: 31.19

GC content: 53.39

Gene sequence:

>663_bases
ATGGACGCACGAGTATGGGGAATAGTCGTAGATTCCTTTGCTAAGCTACTGATTCCCGGTATCACTGTGACCATTCCGCT
GACGCTGATTTCCTTCGCTCTCGGTTTGATACTGGCGATTGTGGTGGCGCTGGTGCGTGTGGCTAAAGTACCTGTGGCCT
CCCAAATCGCGTGGTTCTACATTTGGGTGTTTCGTGGTACGCCGTTGCTGGTGCAGTTGTTCGTTATCTTCTTTGGATTG
CCGTCTGTTGGCATTACGATTCCGGCATTGCCTTCCGCGGTAATCGCGTTCTCGCTGAATGTGGGCGCCTATGCCGCCGA
AACATTGCGTGGTGCGATTCTTGCCGTGCCTAAGGGGCAGCTTGAAGCTGGCTTGGCGGCGAACATGCCGTATGTGACGA
TTATGCGCCGCATTATTCTGCCGCAAGCATTCCGCTCCGCCTTCCCTGCATTGTTCAACTCCTTCATCGCATTGGTCAAG
GACACGTCTCTCGCGGCGAACATCACCGTGGTGGAAATGTTCATGACGGCCCAGCGCATTGTGGCGATTTACTACGAGCC
GCTGGTCCTATACATTGAAGTGGGCTTGATCTACTTGCTCTTCTGCACGTTGCTTGGATGGCTTCAGGATTACTGCGAGA
AGAAGCTCAACGAACACTTCTGA

Upstream 100 bases:

>100_bases
TTTCCCGGCTCTCCTGTAATTAGGGGAGCCGGGAAATATGAGCTGGCCTCGTGAAGATTACGAGCAGGTGCAACATATAC
CACACAACAAAGGATGACCA

Downstream 100 bases:

>100_bases
TGTGTTTATATGGCGGCAGTGCTTGATTCAAGTCGGGTGTTTCCTTGGTTGAAATGCCCGACTTTGTTGTTTCTGACGTG
CGACTTGGCTGCTTCAAATA

Product: polar amino acid ABC transporter, inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MDARVWGIVVDSFAKLLIPGITVTIPLTLISFALGLILAIVVALVRVAKVPVASQIAWFYIWVFRGTPLLVQLFVIFFGL
PSVGITIPALPSAVIAFSLNVGAYAAETLRGAILAVPKGQLEAGLAANMPYVTIMRRIILPQAFRSAFPALFNSFIALVK
DTSLAANITVVEMFMTAQRIVAIYYEPLVLYIEVGLIYLLFCTLLGWLQDYCEKKLNEHF

Sequences:

>Translated_220_residues
MDARVWGIVVDSFAKLLIPGITVTIPLTLISFALGLILAIVVALVRVAKVPVASQIAWFYIWVFRGTPLLVQLFVIFFGL
PSVGITIPALPSAVIAFSLNVGAYAAETLRGAILAVPKGQLEAGLAANMPYVTIMRRIILPQAFRSAFPALFNSFIALVK
DTSLAANITVVEMFMTAQRIVAIYYEPLVLYIEVGLIYLLFCTLLGWLQDYCEKKLNEHF
>Mature_220_residues
MDARVWGIVVDSFAKLLIPGITVTIPLTLISFALGLILAIVVALVRVAKVPVASQIAWFYIWVFRGTPLLVQLFVIFFGL
PSVGITIPALPSAVIAFSLNVGAYAAETLRGAILAVPKGQLEAGLAANMPYVTIMRRIILPQAFRSAFPALFNSFIALVK
DTSLAANITVVEMFMTAQRIVAIYYEPLVLYIEVGLIYLLFCTLLGWLQDYCEKKLNEHF

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=212, Percent_Identity=46.6981132075472, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=34.3137254901961, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1788645, Length=210, Percent_Identity=32.8571428571429, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87082239, Length=207, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1787086, Length=210, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788646, Length=215, Percent_Identity=29.3023255813954, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787087, Length=219, Percent_Identity=31.0502283105023, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1786873, Length=221, Percent_Identity=28.9592760180996, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786874, Length=210, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI48994930, Length=89, Percent_Identity=38.2022471910112, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 24152; Mature: 24152

Theoretical pI: Translated: 9.03; Mature: 9.03

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDARVWGIVVDSFAKLLIPGITVTIPLTLISFALGLILAIVVALVRVAKVPVASQIAWFY
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
IWVFRGTPLLVQLFVIFFGLPSVGITIPALPSAVIAFSLNVGAYAAETLRGAILAVPKGQ
HHHHCCCHHHHHHHHHHHCCCCCCEECCCCHHHHHHHCCCCCHHHHHHHCCHHEECCCCH
LEAGLAANMPYVTIMRRIILPQAFRSAFPALFNSFIALVKDTSLAANITVVEMFMTAQRI
HHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VAIYYEPLVLYIEVGLIYLLFCTLLGWLQDYCEKKLNEHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDARVWGIVVDSFAKLLIPGITVTIPLTLISFALGLILAIVVALVRVAKVPVASQIAWFY
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
IWVFRGTPLLVQLFVIFFGLPSVGITIPALPSAVIAFSLNVGAYAAETLRGAILAVPKGQ
HHHHCCCHHHHHHHHHHHCCCCCCEECCCCHHHHHHHCCCCCHHHHHHHCCHHEECCCCH
LEAGLAANMPYVTIMRRIILPQAFRSAFPALFNSFIALVKDTSLAANITVVEMFMTAQRI
HHCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
VAIYYEPLVLYIEVGLIYLLFCTLLGWLQDYCEKKLNEHF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]