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The map label for this gene is carA [H]

Identifier: 213691633

GI number: 213691633

Start: 854757

End: 855980

Strand: Direct

Name: carA [H]

Synonym: Blon_0737

Alternate gene names: 213691633

Gene position: 854757-855980 (Clockwise)

Preceding gene: 213691632

Following gene: 213691634

Centisome position: 30.17

GC content: 63.07

Gene sequence:

>1224_bases
GTGAGCCAGAACGAGTCCGGGACCATCGCAATTCCGATGTATGACAAGGACGATGCAGTCCTCGTTTTGGAAGATGGACA
GGTATATGTGGGGGAGCCGTATGGCGCCCTCGGTGAGACGACCGGTGAGATCGTCTTCGCCACCGGTATGACCGGATACC
AGGAGACGCTCACCGATCCGAGCTACGATCGCCAGATCGTTGTGCAGACGTTCCCGCACATCGGCGATACCGGCGTCAAC
AGCGAAGACCCTGAGTCCTCCCGCATCTGGGTTGCCGGATACATCGTGCGTGATCCCTCTCCGAACGTGAGCAACTGGCG
TGCCGAAGGCAGCCTTGATGACGACCTCACCAAGAACGGCATCGTCGGCCTGAGCCACATCGACACCCGCAAGCTGGTGC
GTCACCTGCGTTCCGCAGGCGTGATGCGCGCCGGTATCTTCTCCGGCGACGCCCTGACCGACCAGGCCACCGGCGCGCTC
AAGACCATCGAGCAGCTGCTCGAAGACGTCAGGAACACCCCGCAGATGCAGGGCCTGAGCCTGTACGACGAGGTGTCCAC
CAAGGAGACCTACACCATCGAGCCATGCGGCGAGTACGAAGGCAAGGAGCCGCTGTACACCGTGGCCGCCGTGGACCTCG
GCATCAAGGGCATGACCCCGCACCGCATGGCCGAACGCGGCTGCCGCGTGCACGTGGTGCCCTCCACCATCACCTTCGCC
GAAATCGAGAGCCTGAACCCGGACGGCGTCTTCTTCTCCAACGGCCCGGGCGACCCGGAACAGGCCGGCCCCGAAATCGA
GCTGCTGCGCCAGGTGCTCGACGCCGGCTACCCGTTCTTCGGCATCTGCTTCGGCAACCAGCTGCTTGGCCGCGCGCTCG
GCTTCGGCACCTTCAAGCTCAAGTTCGGTCACCGTGGCATCAACCAGCCGGTCAAGGATCTGACCACCGGCAAGGTCGAG
GTCACCGCCCACAACCACGGCTTCGCGGTCGACGCTCCGATCGGCAAGCAGGTCGACGCGCCGTTTGAAAACGGCAAGTA
CGGCAAGGTGTTCGTCTCCCACATCGATCTGAACGACGACGTGGTCGAAGGCCTGCAGTGCGTGGACATCCCCGCATTCT
CCGTGCAGTACCACCCGGAGGCCGCAGCAGGCCCGCACGATGCGGCCTACCTGTTCGACCGTTTCTGCGAACTTATGAAG
AACAACTCCAAGGAAGGTAAGTGA

Upstream 100 bases:

>100_bases
CAGCCCCGCCAGCGGGGTGAGACTTTGCGCCCAACGGCGTGTGAGTCTGCGCTGGCCGTTAACCTTGGTACGAATACCCG
AAAAACATAAGGGGGTTTTG

Downstream 100 bases:

>100_bases
TATGCCGAAGCGCACCGACATCAAATCCGTGATGGTCATCGGCTCCGGCCCGATCGTGATCGGTCAGGCTGCGGAGTTCG
ATTACTCGGGCACCCAGGCA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MSQNESGTIAIPMYDKDDAVLVLEDGQVYVGEPYGALGETTGEIVFATGMTGYQETLTDPSYDRQIVVQTFPHIGDTGVN
SEDPESSRIWVAGYIVRDPSPNVSNWRAEGSLDDDLTKNGIVGLSHIDTRKLVRHLRSAGVMRAGIFSGDALTDQATGAL
KTIEQLLEDVRNTPQMQGLSLYDEVSTKETYTIEPCGEYEGKEPLYTVAAVDLGIKGMTPHRMAERGCRVHVVPSTITFA
EIESLNPDGVFFSNGPGDPEQAGPEIELLRQVLDAGYPFFGICFGNQLLGRALGFGTFKLKFGHRGINQPVKDLTTGKVE
VTAHNHGFAVDAPIGKQVDAPFENGKYGKVFVSHIDLNDDVVEGLQCVDIPAFSVQYHPEAAAGPHDAAYLFDRFCELMK
NNSKEGK

Sequences:

>Translated_407_residues
MSQNESGTIAIPMYDKDDAVLVLEDGQVYVGEPYGALGETTGEIVFATGMTGYQETLTDPSYDRQIVVQTFPHIGDTGVN
SEDPESSRIWVAGYIVRDPSPNVSNWRAEGSLDDDLTKNGIVGLSHIDTRKLVRHLRSAGVMRAGIFSGDALTDQATGAL
KTIEQLLEDVRNTPQMQGLSLYDEVSTKETYTIEPCGEYEGKEPLYTVAAVDLGIKGMTPHRMAERGCRVHVVPSTITFA
EIESLNPDGVFFSNGPGDPEQAGPEIELLRQVLDAGYPFFGICFGNQLLGRALGFGTFKLKFGHRGINQPVKDLTTGKVE
VTAHNHGFAVDAPIGKQVDAPFENGKYGKVFVSHIDLNDDVVEGLQCVDIPAFSVQYHPEAAAGPHDAAYLFDRFCELMK
NNSKEGK
>Mature_406_residues
SQNESGTIAIPMYDKDDAVLVLEDGQVYVGEPYGALGETTGEIVFATGMTGYQETLTDPSYDRQIVVQTFPHIGDTGVNS
EDPESSRIWVAGYIVRDPSPNVSNWRAEGSLDDDLTKNGIVGLSHIDTRKLVRHLRSAGVMRAGIFSGDALTDQATGALK
TIEQLLEDVRNTPQMQGLSLYDEVSTKETYTIEPCGEYEGKEPLYTVAAVDLGIKGMTPHRMAERGCRVHVVPSTITFAE
IESLNPDGVFFSNGPGDPEQAGPEIELLRQVLDAGYPFFGICFGNQLLGRALGFGTFKLKFGHRGINQPVKDLTTGKVEV
TAHNHGFAVDAPIGKQVDAPFENGKYGKVFVSHIDLNDDVVEGLQCVDIPAFSVQYHPEAAAGPHDAAYLFDRFCELMKN
NSKEGK

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=397, Percent_Identity=36.7758186397985, Blast_Score=210, Evalue=1e-54,
Organism=Homo sapiens, GI21361331, Length=397, Percent_Identity=35.0125944584383, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI169790915, Length=397, Percent_Identity=35.0125944584383, Blast_Score=192, Evalue=6e-49,
Organism=Escherichia coli, GI1786215, Length=399, Percent_Identity=42.6065162907268, Blast_Score=298, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI193204318, Length=395, Percent_Identity=39.4936708860759, Blast_Score=232, Evalue=3e-61,
Organism=Saccharomyces cerevisiae, GI6322331, Length=420, Percent_Identity=36.1904761904762, Blast_Score=213, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6324878, Length=391, Percent_Identity=34.7826086956522, Blast_Score=200, Evalue=3e-52,
Organism=Drosophila melanogaster, GI45555749, Length=404, Percent_Identity=33.9108910891089, Blast_Score=201, Evalue=8e-52,
Organism=Drosophila melanogaster, GI24642586, Length=404, Percent_Identity=33.9108910891089, Blast_Score=201, Evalue=9e-52,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 44281; Mature: 44150

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNESGTIAIPMYDKDDAVLVLEDGQVYVGEPYGALGETTGEIVFATGMTGYQETLTDP
CCCCCCCEEEEEEECCCCEEEEEECCCEEEECCCCCCCCCCCCEEEEECCCCHHHHCCCC
SYDRQIVVQTFPHIGDTGVNSEDPESSRIWVAGYIVRDPSPNVSNWRAEGSLDDDLTKNG
CCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEECCCCCCCCCCCC
IVGLSHIDTRKLVRHLRSAGVMRAGIFSGDALTDQATGALKTIEQLLEDVRNTPQMQGLS
EEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
LYDEVSTKETYTIEPCGEYEGKEPLYTVAAVDLGIKGMTPHRMAERGCRVHVVPSTITFA
HHHHCCCCCEEEECCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHCCCEEEEECCEEEEE
EIESLNPDGVFFSNGPGDPEQAGPEIELLRQVLDAGYPFFGICFGNQLLGRALGFGTFKL
HHHCCCCCCEEECCCCCCHHHCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCEEEE
KFGHRGINQPVKDLTTGKVEVTAHNHGFAVDAPIGKQVDAPFENGKYGKVFVSHIDLNDD
EECCCCCCCCHHHHCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHH
VVEGLQCVDIPAFSVQYHPEAAAGPHDAAYLFDRFCELMKNNSKEGK
HHCCCEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SQNESGTIAIPMYDKDDAVLVLEDGQVYVGEPYGALGETTGEIVFATGMTGYQETLTDP
CCCCCCEEEEEEECCCCEEEEEECCCEEEECCCCCCCCCCCCEEEEECCCCHHHHCCCC
SYDRQIVVQTFPHIGDTGVNSEDPESSRIWVAGYIVRDPSPNVSNWRAEGSLDDDLTKNG
CCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCEEECCCCCCCCCCCC
IVGLSHIDTRKLVRHLRSAGVMRAGIFSGDALTDQATGALKTIEQLLEDVRNTPQMQGLS
EEEECCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
LYDEVSTKETYTIEPCGEYEGKEPLYTVAAVDLGIKGMTPHRMAERGCRVHVVPSTITFA
HHHHCCCCCEEEECCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHCCCEEEEECCEEEEE
EIESLNPDGVFFSNGPGDPEQAGPEIELLRQVLDAGYPFFGICFGNQLLGRALGFGTFKL
HHHCCCCCCEEECCCCCCHHHCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCEEEE
KFGHRGINQPVKDLTTGKVEVTAHNHGFAVDAPIGKQVDAPFENGKYGKVFVSHIDLNDD
EECCCCCCCCHHHHCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHH
VVEGLQCVDIPAFSVQYHPEAAAGPHDAAYLFDRFCELMKNNSKEGK
HHCCCEEECCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA