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The map label for this gene is ung [H]

Identifier: 213691587

GI number: 213691587

Start: 793971

End: 794660

Strand: Reverse

Name: ung [H]

Synonym: Blon_0691

Alternate gene names: 213691587

Gene position: 794660-793971 (Counterclockwise)

Preceding gene: 213691591

Following gene: 213691586

Centisome position: 28.05

GC content: 60.29

Gene sequence:

>690_bases
ATGATCAAACCATTGAGCGAACTGGTAGAGCCGGGGTGGGCCCATGCCTTGGCCGACGTGGAGCCCACCATCCACCATAT
GGGCGATTTTCTTCGTGCGGAAAACGCCGCCGGACGCCCGTGGCTGCCGGCAAGCCACAATATTCTGCGCGCGTTCACCA
TCCCGTTCGATTCCATCAAGGTGCTGATTGTCGGCCAGGACCCCTACCCGACCCCGGGTCACCCGGTGGGCTTGAGCTTC
TGCGTGGCGCCGAATGTTCACCCGCTGCCGAAAAGCCTGGTCAATATTTATAAGGAATTGGTTGACGACCTTGGGGCGCC
CATGCCCACCAATGGCGATCTGACACCGTGGACGGAACGTGGGGTGATGTTGCTCAACAGATGTCTGACCGTCGGCGTCG
GGCGGCCGAATTCGCATCAGGGCAAAGGCTGGGAGGAAGTCACCGAGGCCGCGATTCGTGCGTTGAACGCGCGCACGGAC
GCCGATGGCAAGCCCAAGCCGCTGGTGGCGATTCTCTGGGGGCGTAATGCGCAAAGCCTCGAGCCATTGCTGACCAATGC
CTTCATTATCAAATCGCCTCACCCGAGTCCGCTGTCCGCTTCCCGCGGATTCTTCGGCTCCAAACCATTCTCCAGAGCCA
ATCAAGCCCTAGTCACCATGGGTGCCGAACCGGTGGATTGGACTCTTTAG

Upstream 100 bases:

>100_bases
CTGTCAAAACTACCCATGAGTGTAATCGGCAAACAACTCATCAGTCCACCACACCACGCCCCGTGCACCGGATATGCACG
TTTGACTACAGTGGTGAGTC

Downstream 100 bases:

>100_bases
ACAGACCAACAGTCATTGTAAGTAGTTACAGTGGGGACATGACTTTGTTCCCCACGCAACCGAACATACCTTCGCAGACC
ACCGCCGCACGACCGGTCAC

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MIKPLSELVEPGWAHALADVEPTIHHMGDFLRAENAAGRPWLPASHNILRAFTIPFDSIKVLIVGQDPYPTPGHPVGLSF
CVAPNVHPLPKSLVNIYKELVDDLGAPMPTNGDLTPWTERGVMLLNRCLTVGVGRPNSHQGKGWEEVTEAAIRALNARTD
ADGKPKPLVAILWGRNAQSLEPLLTNAFIIKSPHPSPLSASRGFFGSKPFSRANQALVTMGAEPVDWTL

Sequences:

>Translated_229_residues
MIKPLSELVEPGWAHALADVEPTIHHMGDFLRAENAAGRPWLPASHNILRAFTIPFDSIKVLIVGQDPYPTPGHPVGLSF
CVAPNVHPLPKSLVNIYKELVDDLGAPMPTNGDLTPWTERGVMLLNRCLTVGVGRPNSHQGKGWEEVTEAAIRALNARTD
ADGKPKPLVAILWGRNAQSLEPLLTNAFIIKSPHPSPLSASRGFFGSKPFSRANQALVTMGAEPVDWTL
>Mature_229_residues
MIKPLSELVEPGWAHALADVEPTIHHMGDFLRAENAAGRPWLPASHNILRAFTIPFDSIKVLIVGQDPYPTPGHPVGLSF
CVAPNVHPLPKSLVNIYKELVDDLGAPMPTNGDLTPWTERGVMLLNRCLTVGVGRPNSHQGKGWEEVTEAAIRALNARTD
ADGKPKPLVAILWGRNAQSLEPLLTNAFIIKSPHPSPLSASRGFFGSKPFSRANQALVTMGAEPVDWTL

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=172, Percent_Identity=43.0232558139535, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI6224979, Length=172, Percent_Identity=43.0232558139535, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI1788934, Length=199, Percent_Identity=39.6984924623116, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17556304, Length=208, Percent_Identity=40.8653846153846, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6323620, Length=240, Percent_Identity=39.5833333333333, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 24833; Mature: 24833

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKPLSELVEPGWAHALADVEPTIHHMGDFLRAENAAGRPWLPASHNILRAFTIPFDSIK
CCCCHHHHCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEE
VLIVGQDPYPTPGHPVGLSFCVAPNVHPLPKSLVNIYKELVDDLGAPMPTNGDLTPWTER
EEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
GVMLLNRCLTVGVGRPNSHQGKGWEEVTEAAIRALNARTDADGKPKPLVAILWGRNAQSL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHH
EPLLTNAFIIKSPHPSPLSASRGFFGSKPFSRANQALVTMGAEPVDWTL
HHHHHCEEEEECCCCCCCCCCCCCCCCCCHHHHCCEEEEECCCCCCCCC
>Mature Secondary Structure
MIKPLSELVEPGWAHALADVEPTIHHMGDFLRAENAAGRPWLPASHNILRAFTIPFDSIK
CCCCHHHHCCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEE
VLIVGQDPYPTPGHPVGLSFCVAPNVHPLPKSLVNIYKELVDDLGAPMPTNGDLTPWTER
EEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHH
GVMLLNRCLTVGVGRPNSHQGKGWEEVTEAAIRALNARTDADGKPKPLVAILWGRNAQSL
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHH
EPLLTNAFIIKSPHPSPLSASRGFFGSKPFSRANQALVTMGAEPVDWTL
HHHHHCEEEEECCCCCCCCCCCCCCCCCCHHHHCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]