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The map label for this gene is ywlC [H]

Identifier: 213691485

GI number: 213691485

Start: 657644

End: 658345

Strand: Direct

Name: ywlC [H]

Synonym: Blon_0582

Alternate gene names: 213691485

Gene position: 657644-658345 (Clockwise)

Preceding gene: 213691484

Following gene: 213691486

Centisome position: 23.22

GC content: 63.39

Gene sequence:

>702_bases
GTGAATACACAGGCGAACGGAGGTGGCGTGAGCGTGGAGGGCGGAACAACGCTGAAGGTCACGGATGAATCGCTGGCACA
GGCGGCGCGTGTCATCCGGGATGGTGGATTGGTCGTCATTCCAACGGATACGGTATATGGAGTGGCGTGCGATCCGCGTA
ATAAGGCCGCTATCGACCGTATCTACCGGCTCAAGCGTCGCCCGCGCTATAAGGCGTTGCAGGTACTGCTCGCATCCACC
GACCAGCTTGATGAGCTCAGTCTAGACCTGCCGTCTCCACTGAATCGTTTGTCGGCGGCGTTCCTGCCCGGCGCGTTCTC
GCCGATTGCCGTAGCCCGGCCCGACTGCACGTTGGAGACTTTGGCCGACACCGCCGATGGTCGCCCCGGCACGCAGGGCA
TCCGCATCCCCAATTCGGCGCTGTGCCTCGCGATTCTCAAGGCCACTGGTCCGCTGGCCGCGTCCAGCGCCAACCGTTCC
GGCGACGAAAGCGCACAGACCGTCCAGGAGGCGGTTGATGCGTTCGGCAGCGAAGTCGACCTGTATCTGGACGGCGGTCC
CACCCAAGGCCATGTCTCCAGCACCGTCGTCAAAGCCGATCCGTATGCGCGCGACGGCATCGAGATCCTGCGTGAAGGCG
TCATCGCCCAAAACGTGATTCGCAAGGCCCTCCACCTCAACGGCGGGGGACTTGGCGCATGA

Upstream 100 bases:

>100_bases
TCTACGGTCTGTGCGTGTGGGGCGAATCGGAAAACGGCAGTACGGCAAACGAGCGATGATGAACTATGCAAGTCGGGGCG
CAATGGTGCAATGGTAGATT

Downstream 100 bases:

>100_bases
GAATCTACTTACTGATTGCCGCCATCGCCGGTGGCGTCACCTGGCTGGTGACTCCGCTGATTCGCCACGTCGCCATCGAA
ATCGGTGCGGTTGGCGAGGT

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MNTQANGGGVSVEGGTTLKVTDESLAQAARVIRDGGLVVIPTDTVYGVACDPRNKAAIDRIYRLKRRPRYKALQVLLAST
DQLDELSLDLPSPLNRLSAAFLPGAFSPIAVARPDCTLETLADTADGRPGTQGIRIPNSALCLAILKATGPLAASSANRS
GDESAQTVQEAVDAFGSEVDLYLDGGPTQGHVSSTVVKADPYARDGIEILREGVIAQNVIRKALHLNGGGLGA

Sequences:

>Translated_233_residues
MNTQANGGGVSVEGGTTLKVTDESLAQAARVIRDGGLVVIPTDTVYGVACDPRNKAAIDRIYRLKRRPRYKALQVLLAST
DQLDELSLDLPSPLNRLSAAFLPGAFSPIAVARPDCTLETLADTADGRPGTQGIRIPNSALCLAILKATGPLAASSANRS
GDESAQTVQEAVDAFGSEVDLYLDGGPTQGHVSSTVVKADPYARDGIEILREGVIAQNVIRKALHLNGGGLGA
>Mature_233_residues
MNTQANGGGVSVEGGTTLKVTDESLAQAARVIRDGGLVVIPTDTVYGVACDPRNKAAIDRIYRLKRRPRYKALQVLLAST
DQLDELSLDLPSPLNRLSAAFLPGAFSPIAVARPDCTLETLADTADGRPGTQGIRIPNSALCLAILKATGPLAASSANRS
GDESAQTVQEAVDAFGSEVDLYLDGGPTQGHVSSTVVKADPYARDGIEILREGVIAQNVIRKALHLNGGGLGA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI87081864, Length=192, Percent_Identity=27.0833333333333, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI2367210, Length=196, Percent_Identity=29.0816326530612, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17537239, Length=218, Percent_Identity=30.2752293577982, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=191, Percent_Identity=30.3664921465969, Blast_Score=69, Evalue=5e-13,
Organism=Drosophila melanogaster, GI78707274, Length=201, Percent_Identity=31.3432835820896, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 24243; Mature: 24243

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTQANGGGVSVEGGTTLKVTDESLAQAARVIRDGGLVVIPTDTVYGVACDPRNKAAIDR
CCCCCCCCEEEECCCCEEEECHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHH
IYRLKRRPRYKALQVLLASTDQLDELSLDLPSPLNRLSAAFLPGAFSPIAVARPDCTLET
HHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCEEECCCCHHHH
LADTADGRPGTQGIRIPNSALCLAILKATGPLAASSANRSGDESAQTVQEAVDAFGSEVD
HHHCCCCCCCCCCEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
LYLDGGPTQGHVSSTVVKADPYARDGIEILREGVIAQNVIRKALHLNGGGLGA
EEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNTQANGGGVSVEGGTTLKVTDESLAQAARVIRDGGLVVIPTDTVYGVACDPRNKAAIDR
CCCCCCCCEEEECCCCEEEECHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHHHHH
IYRLKRRPRYKALQVLLASTDQLDELSLDLPSPLNRLSAAFLPGAFSPIAVARPDCTLET
HHHHHCCCHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHHHHCCCCCCCCEEECCCCHHHH
LADTADGRPGTQGIRIPNSALCLAILKATGPLAASSANRSGDESAQTVQEAVDAFGSEVD
HHHCCCCCCCCCCEECCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEE
LYLDGGPTQGHVSSTVVKADPYARDGIEILREGVIAQNVIRKALHLNGGGLGA
EEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]