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The map label for this gene is tesB [H]

Identifier: 213691459

GI number: 213691459

Start: 625774

End: 626679

Strand: Reverse

Name: tesB [H]

Synonym: Blon_0554

Alternate gene names: 213691459

Gene position: 626679-625774 (Counterclockwise)

Preceding gene: 213691460

Following gene: 213691446

Centisome position: 22.12

GC content: 59.38

Gene sequence:

>906_bases
ATGGCTCAGGCAACCACCGTAACTCCATTGGACCATCTGGTGAAGGTGCTGAAGTTGGGCGAGCCTTCCGCTTACCGCAA
TCACACATACATCAATGGCGAGAGTATGTACTTCCCCACTGGCCGCGTCTACGGTGGCCAGGTCATCGCCCAGTCGGTGA
TCGCCGCGTCCAAAACAGTAGGCCCTTCACGCCTGCCGCATTCGGTACATGGCTATTTCATTGCCGCCGGCGATATTCGT
CAAGACCTGCTGTTTGACGTCGAGAACCTTCGCGACGGCCGCTCGTTCTCCGCTCGTCGGGTCAACGTCACCCAAGCCGA
GGGGTCGATTCTCACGGCCATCGCCTCCTTCCAGGAGACCGGTCAGGAGGGTGTGGAATTTGCCGATCCGATGCCGGAAA
ACCTGCCCGATCCCGAAACGTTGACTTCCGCCAAGGAGCTCATGCGCCCGTATGCCGCACAGTCGCCGTTCGCCAATTAC
TATGCCGAGAAATCGCCGTTCGATATCCGCCACGTGACGCCGACCGTGATGCTGCGCGCGGACAAGGATTCCGCCGAGCA
TGATTCCGGCAAGCAGATGGTGTGGATGAAGGCCGATGGCCACGTCGATGTGCCGCAGGTCATGCATCGTGCGATGCTGG
CACTCGGCTGCGATCAGGTGATGATGGAACCGGTGCTGCGCCGCGCCGGACTGTCGATTTCCACACCGGGCATTTCCTAT
GCGTCCATCGACCATTCGATGTGGTGGTATCAGGATATCGATATCAACGAATGGCATTTGTATGTGCAGGATACGCCTAT
CGCCGCGCACGGGCGCGGACTCGGCATCGCCAAAGTGTATGCGCAGAATGGCGACTTGGTGGCGGCCATCGCTCAGGAAG
CTATGGTTCGCGTGCCGCAGGAATAG

Upstream 100 bases:

>100_bases
GCTCCCGGAACTCTTAACCCCCACCGGATAGACTGCCAACCATAGGTTGGAATACGATAACCGAATATCGAACACAGCAG
AACAGGAATCGAGGAACGCC

Downstream 100 bases:

>100_bases
TGGGAATCGGCTTGGCCGATGGTGTGGTTTTTTCTTCTTCTCTCCCCCAGTCGGCTACGCCTACAGCCCCCTCGTCAGAG
GGGGCTTATCACGGATTATC

Product: acyl-CoA thioesterase

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MAQATTVTPLDHLVKVLKLGEPSAYRNHTYINGESMYFPTGRVYGGQVIAQSVIAASKTVGPSRLPHSVHGYFIAAGDIR
QDLLFDVENLRDGRSFSARRVNVTQAEGSILTAIASFQETGQEGVEFADPMPENLPDPETLTSAKELMRPYAAQSPFANY
YAEKSPFDIRHVTPTVMLRADKDSAEHDSGKQMVWMKADGHVDVPQVMHRAMLALGCDQVMMEPVLRRAGLSISTPGISY
ASIDHSMWWYQDIDINEWHLYVQDTPIAAHGRGLGIAKVYAQNGDLVAAIAQEAMVRVPQE

Sequences:

>Translated_301_residues
MAQATTVTPLDHLVKVLKLGEPSAYRNHTYINGESMYFPTGRVYGGQVIAQSVIAASKTVGPSRLPHSVHGYFIAAGDIR
QDLLFDVENLRDGRSFSARRVNVTQAEGSILTAIASFQETGQEGVEFADPMPENLPDPETLTSAKELMRPYAAQSPFANY
YAEKSPFDIRHVTPTVMLRADKDSAEHDSGKQMVWMKADGHVDVPQVMHRAMLALGCDQVMMEPVLRRAGLSISTPGISY
ASIDHSMWWYQDIDINEWHLYVQDTPIAAHGRGLGIAKVYAQNGDLVAAIAQEAMVRVPQE
>Mature_300_residues
AQATTVTPLDHLVKVLKLGEPSAYRNHTYINGESMYFPTGRVYGGQVIAQSVIAASKTVGPSRLPHSVHGYFIAAGDIRQ
DLLFDVENLRDGRSFSARRVNVTQAEGSILTAIASFQETGQEGVEFADPMPENLPDPETLTSAKELMRPYAAQSPFANYY
AEKSPFDIRHVTPTVMLRADKDSAEHDSGKQMVWMKADGHVDVPQVMHRAMLALGCDQVMMEPVLRRAGLSISTPGISYA
SIDHSMWWYQDIDINEWHLYVQDTPIAAHGRGLGIAKVYAQNGDLVAAIAQEAMVRVPQE

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=277, Percent_Identity=29.6028880866426, Blast_Score=126, Evalue=2e-29,
Organism=Escherichia coli, GI1786657, Length=269, Percent_Identity=34.2007434944238, Blast_Score=150, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI71988741, Length=273, Percent_Identity=29.6703296703297, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17558508, Length=279, Percent_Identity=30.8243727598566, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17531885, Length=276, Percent_Identity=26.4492753623188, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17531889, Length=276, Percent_Identity=26.4492753623188, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI115532456, Length=276, Percent_Identity=26.4492753623188, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71982224, Length=296, Percent_Identity=23.9864864864865, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI212645202, Length=277, Percent_Identity=28.5198555956679, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 33186; Mature: 33055

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQATTVTPLDHLVKVLKLGEPSAYRNHTYINGESMYFPTGRVYGGQVIAQSVIAASKTV
CCCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCEEECCCCCCCCHHHHHHHHHHHHHCC
GPSRLPHSVHGYFIAAGDIRQDLLFDVENLRDGRSFSARRVNVTQAEGSILTAIASFQET
CCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
GQEGVEFADPMPENLPDPETLTSAKELMRPYAAQSPFANYYAEKSPFDIRHVTPTVMLRA
CHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCEEEEEEE
DKDSAEHDSGKQMVWMKADGHVDVPQVMHRAMLALGCDQVMMEPVLRRAGLSISTPGISY
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCEECCCCCEE
ASIDHSMWWYQDIDINEWHLYVQDTPIAAHGRGLGIAKVYAQNGDLVAAIAQEAMVRVPQ
EECCCCEEEEEECCCCEEEEEEECCCEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCC
E
C
>Mature Secondary Structure 
AQATTVTPLDHLVKVLKLGEPSAYRNHTYINGESMYFPTGRVYGGQVIAQSVIAASKTV
CCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCCEEECCCCCCCCHHHHHHHHHHHHHCC
GPSRLPHSVHGYFIAAGDIRQDLLFDVENLRDGRSFSARRVNVTQAEGSILTAIASFQET
CCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
GQEGVEFADPMPENLPDPETLTSAKELMRPYAAQSPFANYYAEKSPFDIRHVTPTVMLRA
CHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECCEEEEEEE
DKDSAEHDSGKQMVWMKADGHVDVPQVMHRAMLALGCDQVMMEPVLRRAGLSISTPGISY
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCEECCCCCEE
ASIDHSMWWYQDIDINEWHLYVQDTPIAAHGRGLGIAKVYAQNGDLVAAIAQEAMVRVPQ
EECCCCEEEEEECCCCEEEEEEECCCEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]