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The map label for this gene is galE [H]

Identifier: 213691443

GI number: 213691443

Start: 604901

End: 605914

Strand: Direct

Name: galE [H]

Synonym: Blon_0538

Alternate gene names: 213691443

Gene position: 604901-605914 (Clockwise)

Preceding gene: 213691441

Following gene: 213691445

Centisome position: 21.35

GC content: 64.3

Gene sequence:

>1014_bases
ATGACAGTTCTCGTCACCGGCGGCTGCGGCTACATCGGCGCGCATGTCGTTCACGCACTCCATCAGGCCGGCGAAAAGGT
CGTCGTCGTCGACGATCTGAGCTACGGCAAGCCCACTCGCATCGAAGGCTCCCGCCTGTACGGCATGGATATTGCCGCCC
CGGGTGCCGGCGAGCGTCTGGCCGAAATCCTCGACGCCGAAGGCGTCGACTCCGTGATCCACTTCGCCGCGCGCAAGCAG
GTCGGCGAATCCGTGGAGAAGCCGCTGTGGTACTACCAGCAGAACATCAACGGCATGCTCAACGTGCTCACCGGCATGAC
CCAATCCAAGAACGCCAAGAAGCTCGTCTTCTCCTCCTCCGCCGCCACCTACGGTGTGCCGCCGGTCGACGTGGTGCCCG
AGGACGTCGTTCCGATGCTGCCGATCAACCCCTACGGCCAGACCAAGCTGTTCGGCGAATGGATGGCCCGCGCCTGCGAG
CAGCCGTTCGGCATCCGCTTCTGCGCGTTGCGCTACTTCAACGTGGCCGGCTGCGGCCCGGTCGAACTCGAAGACCCGGC
TATTCTGAACCTCATCCCGATGCTGTTCAACCGCCTCAAGCAGGGCAAGGCCCCCGCCATCTTCGGTGACGACTATCCGA
CCCCGGACGGCACCTGCGTGCGCGACTACATCCACGTTTCCGATCTGGCCGATGCCCACATCGCCGCCCTCAAGTACCTC
GATCGTGACGAGCGCAAGTACGACGCCTTCAATGTCGGCACCGGTGAAGGCACCTCCGTGCGTCAGATCGTCGACGAAGT
CAAGAAGGTCACCGGTCTGCCGTTCACCGAGGCCGTCATGGCCCGCCGCGCCGGCGACCCGCCGCACCTGATCGGCTCCC
CGAAGCGCATCAACGAGGAGATGGGCTGGCACGCCAAGTACGACGTGGAAGACATCGTCAAGTCCGCGTGGGATGCCTGG
CAGGCCAACCCCGAACACCACATCGACGTCGACACCTGGAAGCAGGCTGACTGA

Upstream 100 bases:

>100_bases
TACTAAAATTGTTTCAAAAGGTAACAAAGCGGACCAAAAGTGAACAGCCGCTGAACTCCCGACGGCCGACACTTGCAACC
CGCACAAGGAAAGGTCAACT

Downstream 100 bases:

>100_bases
GATTGACGATTGCTTTGCGGTGGATGCCGTGAAGCGTTTCCGTCCATAAGGGCGTGGCCGGGGTTCCGGTCGCGCCCTTC
GTCGTTTTGTGGATGTTTGT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTVLVTGGCGYIGAHVVHALHQAGEKVVVVDDLSYGKPTRIEGSRLYGMDIAAPGAGERLAEILDAEGVDSVIHFAARKQ
VGESVEKPLWYYQQNINGMLNVLTGMTQSKNAKKLVFSSSAATYGVPPVDVVPEDVVPMLPINPYGQTKLFGEWMARACE
QPFGIRFCALRYFNVAGCGPVELEDPAILNLIPMLFNRLKQGKAPAIFGDDYPTPDGTCVRDYIHVSDLADAHIAALKYL
DRDERKYDAFNVGTGEGTSVRQIVDEVKKVTGLPFTEAVMARRAGDPPHLIGSPKRINEEMGWHAKYDVEDIVKSAWDAW
QANPEHHIDVDTWKQAD

Sequences:

>Translated_337_residues
MTVLVTGGCGYIGAHVVHALHQAGEKVVVVDDLSYGKPTRIEGSRLYGMDIAAPGAGERLAEILDAEGVDSVIHFAARKQ
VGESVEKPLWYYQQNINGMLNVLTGMTQSKNAKKLVFSSSAATYGVPPVDVVPEDVVPMLPINPYGQTKLFGEWMARACE
QPFGIRFCALRYFNVAGCGPVELEDPAILNLIPMLFNRLKQGKAPAIFGDDYPTPDGTCVRDYIHVSDLADAHIAALKYL
DRDERKYDAFNVGTGEGTSVRQIVDEVKKVTGLPFTEAVMARRAGDPPHLIGSPKRINEEMGWHAKYDVEDIVKSAWDAW
QANPEHHIDVDTWKQAD
>Mature_336_residues
TVLVTGGCGYIGAHVVHALHQAGEKVVVVDDLSYGKPTRIEGSRLYGMDIAAPGAGERLAEILDAEGVDSVIHFAARKQV
GESVEKPLWYYQQNINGMLNVLTGMTQSKNAKKLVFSSSAATYGVPPVDVVPEDVVPMLPINPYGQTKLFGEWMARACEQ
PFGIRFCALRYFNVAGCGPVELEDPAILNLIPMLFNRLKQGKAPAIFGDDYPTPDGTCVRDYIHVSDLADAHIAALKYLD
RDERKYDAFNVGTGEGTSVRQIVDEVKKVTGLPFTEAVMARRAGDPPHLIGSPKRINEEMGWHAKYDVEDIVKSAWDAWQ
ANPEHHIDVDTWKQAD

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=342, Percent_Identity=38.5964912280702, Blast_Score=184, Evalue=7e-47,
Organism=Homo sapiens, GI56118217, Length=342, Percent_Identity=38.5964912280702, Blast_Score=184, Evalue=7e-47,
Organism=Homo sapiens, GI189083684, Length=342, Percent_Identity=38.5964912280702, Blast_Score=184, Evalue=7e-47,
Organism=Homo sapiens, GI7657641, Length=284, Percent_Identity=22.887323943662, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1786974, Length=343, Percent_Identity=37.3177842565598, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1788353, Length=356, Percent_Identity=23.876404494382, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI48994969, Length=289, Percent_Identity=25.2595155709343, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790049, Length=291, Percent_Identity=25.7731958762887, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=348, Percent_Identity=34.7701149425287, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71982038, Length=350, Percent_Identity=34.2857142857143, Blast_Score=167, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17568069, Length=241, Percent_Identity=29.4605809128631, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI115532424, Length=305, Percent_Identity=22.2950819672131, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6319493, Length=341, Percent_Identity=39.2961876832845, Blast_Score=196, Evalue=4e-51,
Organism=Drosophila melanogaster, GI19923002, Length=347, Percent_Identity=35.1585014409222, Blast_Score=174, Evalue=9e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 37039; Mature: 36907

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLVTGGCGYIGAHVVHALHQAGEKVVVVDDLSYGKPTRIEGSRLYGMDIAAPGAGERL
CEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCHHHH
AEILDAEGVDSVIHFAARKQVGESVEKPLWYYQQNINGMLNVLTGMTQSKNAKKLVFSSS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
AATYGVPPVDVVPEDVVPMLPINPYGQTKLFGEWMARACEQPFGIRFCALRYFNVAGCGP
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCC
VELEDPAILNLIPMLFNRLKQGKAPAIFGDDYPTPDGTCVRDYIHVSDLADAHIAALKYL
CCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DRDERKYDAFNVGTGEGTSVRQIVDEVKKVTGLPFTEAVMARRAGDPPHLIGSPKRINEE
CCCCHHCCCEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
MGWHAKYDVEDIVKSAWDAWQANPEHHIDVDTWKQAD
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVLVTGGCGYIGAHVVHALHQAGEKVVVVDDLSYGKPTRIEGSRLYGMDIAAPGAGERL
EEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCEEEEEEECCCCCHHHH
AEILDAEGVDSVIHFAARKQVGESVEKPLWYYQQNINGMLNVLTGMTQSKNAKKLVFSSS
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECC
AATYGVPPVDVVPEDVVPMLPINPYGQTKLFGEWMARACEQPFGIRFCALRYFNVAGCGP
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCC
VELEDPAILNLIPMLFNRLKQGKAPAIFGDDYPTPDGTCVRDYIHVSDLADAHIAALKYL
CCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DRDERKYDAFNVGTGEGTSVRQIVDEVKKVTGLPFTEAVMARRAGDPPHLIGSPKRINEE
CCCCHHCCCEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHH
MGWHAKYDVEDIVKSAWDAWQANPEHHIDVDTWKQAD
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]