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The map label for this gene is fucO [H]

Identifier: 213691445

GI number: 213691445

Start: 608598

End: 609749

Strand: Direct

Name: fucO [H]

Synonym: Blon_0540

Alternate gene names: 213691445

Gene position: 608598-609749 (Clockwise)

Preceding gene: 213691443

Following gene: 213691447

Centisome position: 21.48

GC content: 63.11

Gene sequence:

>1152_bases
ATGGTATACCGCATGATTTTCAACCAGACTGCATACTTCGGACGTGGCTCGATCAAGGAAATTCCGGCCGTCGCCAAGCA
GCACGGCTTCACCAAGGCATTTATCGTCACTGATCCGGTACTGCTGGAGACCGGCACCGCCGAGAAGGTCACCAAGGTTC
TGGATGAGGCCGGCCTGGCGTATGAGGTGTTCTCCAACGTCAAGCCGAACCCGCCGGTAGAGTGCATTAAGGACGGCGTC
GCCAAGTTCGCCGAATCCGGCGCGGACTTCCTGATTGGTCTGGGCGGCGGCTCCCCGCAAGACACCTGCAAGGGCATCGG
CATCATCACCGCCAACCCGGAGTTCGCCGACGTGCTGTCCCTGGAAGGCGTCGCGGATACCAAGAACCCGTCCGTCCCGA
TCTTCGGCGTGCCGACCACCGCCGGTACCGCTTCCGAGACGACCATCAACTACGTGGTCACCGATACCGCCAACAAGCGT
AAGTTCGTGGCCGTCGACCCGCACGACATCCCGATCGTCGCTTTCGTTGATCCTGATCTGACCGACTCGATGCCGCGCGG
CCTGAAGGTCGCCACCGGACTTGACGCCCTGACCCACGCCATCGAGGGTTACATTACCCCGGGTGCCTGGAGCCTGTCCG
ACTGCCTGTCCATGCAGACCATTCGCATGATTGCCCAGAACCTGGCCAAGTCCGCCGATGGCGACATTCCGGCTGGCGAG
CAGATGGCCTACGCGTCCTACATCACCGGCATGGCCTACTCGAACGTGGGCCTCGGCCTGGTGCACGGCATGGCTCACCC
GCTGGGCGGCCGTCTGGGCGTGGCCCACGGTGTGGCCAACGGCATTCTGCTGGCCCCGGTCATGGAATACAACAAGGACT
TCACCGGTGAGAAGTACCGCGACATCGCCGATGCGTTCGGCGTCGAGGACGCCTACACCGGCGACCTGGAGACTGTGCGC
GAAGAGGCCGTGCAGGCCGTCCACAAGCTGACCGTGGATCTGAAGAACCCGACCACGATTTCCGAAGTGGGCGCCACCGA
GGGCGACCTTGAGCCGCTGGCTCACGACGCCTTCAACGACGTGTGCACCCCCGGCAACCCGCGTCAGGCCACGCAGGAGG
ACATCCTCGCCATCTACAAGTCGCTGATGTGA

Upstream 100 bases:

>100_bases
CAGGTGAATGCTCATGCGCGGAGTAGACTGGGGAACCGTTGGACCACTCAAAGAGTGAGCGGACCACCAGTTAAGACACT
AGCTCAAAAGGAGAGTCCCT

Downstream 100 bases:

>100_bases
TTCGTCGATGACGCCGACGATGCCGGTGGGTTCCCCTCGTCGGGAACCCACCGGCATCGCTATCTCTCGTGCTTTTCGTC
GTAGACTTCGTCGGTGGTGG

Product: L-1,2-propanediol oxidoreductase

Products: NA

Alternate protein names: Propanediol oxidoreductase [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MVYRMIFNQTAYFGRGSIKEIPAVAKQHGFTKAFIVTDPVLLETGTAEKVTKVLDEAGLAYEVFSNVKPNPPVECIKDGV
AKFAESGADFLIGLGGGSPQDTCKGIGIITANPEFADVLSLEGVADTKNPSVPIFGVPTTAGTASETTINYVVTDTANKR
KFVAVDPHDIPIVAFVDPDLTDSMPRGLKVATGLDALTHAIEGYITPGAWSLSDCLSMQTIRMIAQNLAKSADGDIPAGE
QMAYASYITGMAYSNVGLGLVHGMAHPLGGRLGVAHGVANGILLAPVMEYNKDFTGEKYRDIADAFGVEDAYTGDLETVR
EEAVQAVHKLTVDLKNPTTISEVGATEGDLEPLAHDAFNDVCTPGNPRQATQEDILAIYKSLM

Sequences:

>Translated_383_residues
MVYRMIFNQTAYFGRGSIKEIPAVAKQHGFTKAFIVTDPVLLETGTAEKVTKVLDEAGLAYEVFSNVKPNPPVECIKDGV
AKFAESGADFLIGLGGGSPQDTCKGIGIITANPEFADVLSLEGVADTKNPSVPIFGVPTTAGTASETTINYVVTDTANKR
KFVAVDPHDIPIVAFVDPDLTDSMPRGLKVATGLDALTHAIEGYITPGAWSLSDCLSMQTIRMIAQNLAKSADGDIPAGE
QMAYASYITGMAYSNVGLGLVHGMAHPLGGRLGVAHGVANGILLAPVMEYNKDFTGEKYRDIADAFGVEDAYTGDLETVR
EEAVQAVHKLTVDLKNPTTISEVGATEGDLEPLAHDAFNDVCTPGNPRQATQEDILAIYKSLM
>Mature_383_residues
MVYRMIFNQTAYFGRGSIKEIPAVAKQHGFTKAFIVTDPVLLETGTAEKVTKVLDEAGLAYEVFSNVKPNPPVECIKDGV
AKFAESGADFLIGLGGGSPQDTCKGIGIITANPEFADVLSLEGVADTKNPSVPIFGVPTTAGTASETTINYVVTDTANKR
KFVAVDPHDIPIVAFVDPDLTDSMPRGLKVATGLDALTHAIEGYITPGAWSLSDCLSMQTIRMIAQNLAKSADGDIPAGE
QMAYASYITGMAYSNVGLGLVHGMAHPLGGRLGVAHGVANGILLAPVMEYNKDFTGEKYRDIADAFGVEDAYTGDLETVR
EEAVQAVHKLTVDLKNPTTISEVGATEGDLEPLAHDAFNDVCTPGNPRQATQEDILAIYKSLM

Specific function: Fucose metabolism; fourth step. [C]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=413, Percent_Identity=23.728813559322, Blast_Score=99, Evalue=9e-21,
Organism=Escherichia coli, GI1789163, Length=381, Percent_Identity=56.6929133858268, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI48994951, Length=373, Percent_Identity=37.8016085790885, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI87082107, Length=374, Percent_Identity=35.0267379679144, Blast_Score=205, Evalue=3e-54,
Organism=Escherichia coli, GI1787493, Length=393, Percent_Identity=33.3333333333333, Blast_Score=185, Evalue=4e-48,
Organism=Escherichia coli, GI1789386, Length=315, Percent_Identity=25.7142857142857, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17537053, Length=416, Percent_Identity=26.9230769230769, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321181, Length=376, Percent_Identity=35.6382978723404, Blast_Score=227, Evalue=3e-60,
Organism=Drosophila melanogaster, GI24657991, Length=429, Percent_Identity=25.8741258741259, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211
- InterPro:   IPR013460 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.77 [H]

Molecular weight: Translated: 40571; Mature: 40571

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYRMIFNQTAYFGRGSIKEIPAVAKQHGFTKAFIVTDPVLLETGTAEKVTKVLDEAGLA
CEEEEEECCHHHCCCCCHHHHHHHHHHCCCEEEEEEECCEEEECCCHHHHHHHHHHCCCH
YEVFSNVKPNPPVECIKDGVAKFAESGADFLIGLGGGSPQDTCKGIGIITANPEFADVLS
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCEEEECCCCHHHHHC
LEGVADTKNPSVPIFGVPTTAGTASETTINYVVTDTANKRKFVAVDPHDIPIVAFVDPDL
CCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCEEEEEECCCC
TDSMPRGLKVATGLDALTHAIEGYITPGAWSLSDCLSMQTIRMIAQNLAKSADGDIPAGE
CCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QMAYASYITGMAYSNVGLGLVHGMAHPLGGRLGVAHGVANGILLAPVMEYNKDFTGEKYR
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHH
DIADAFGVEDAYTGDLETVREEAVQAVHKLTVDLKNPTTISEVGATEGDLEPLAHDAFND
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHCCCCCCCCCHHHHHHHHC
VCTPGNPRQATQEDILAIYKSLM
CCCCCCCCCHHHHHHHHHHHHHC
>Mature Secondary Structure
MVYRMIFNQTAYFGRGSIKEIPAVAKQHGFTKAFIVTDPVLLETGTAEKVTKVLDEAGLA
CEEEEEECCHHHCCCCCHHHHHHHHHHCCCEEEEEEECCEEEECCCHHHHHHHHHHCCCH
YEVFSNVKPNPPVECIKDGVAKFAESGADFLIGLGGGSPQDTCKGIGIITANPEFADVLS
HHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCEEEECCCCHHHHHC
LEGVADTKNPSVPIFGVPTTAGTASETTINYVVTDTANKRKFVAVDPHDIPIVAFVDPDL
CCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEECCCCCEEEEEECCCC
TDSMPRGLKVATGLDALTHAIEGYITPGAWSLSDCLSMQTIRMIAQNLAKSADGDIPAGE
CCCCCCCEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
QMAYASYITGMAYSNVGLGLVHGMAHPLGGRLGVAHGVANGILLAPVMEYNKDFTGEKYR
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHH
DIADAFGVEDAYTGDLETVREEAVQAVHKLTVDLKNPTTISEVGATEGDLEPLAHDAFND
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHCCCCCCCCCHHHHHHHHC
VCTPGNPRQATQEDILAIYKSLM
CCCCCCCCCHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]