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The map label for this gene is mntH [H]

Identifier: 213691353

GI number: 213691353

Start: 512082

End: 513392

Strand: Direct

Name: mntH [H]

Synonym: Blon_0444

Alternate gene names: 213691353

Gene position: 512082-513392 (Clockwise)

Preceding gene: 213691352

Following gene: 213691356

Centisome position: 18.08

GC content: 60.95

Gene sequence:

>1311_bases
ATGACGAACGCTGTGGCAGACATCGAACAGGAAACACCGGAAATCGAGAAGGAACGCCAGCTTGCCGGGGCCGGAGCAGG
GACGAACAACAAGGAAAAGCCGCATGACCATGCGCTGGCCAGCATCCTTGGCCCCGCGTTCGTGGCGGCCGTGGCCTACG
TCGATCCTGGTAATGTGGCGGCCAACATCACCTCCGGCGCACGATACGGCTACCTGTTGGTGTGGGTGCTGGTGCTCGCC
AACGCCATGAGCGTGCTCATCCAGTATCAGTCCGCCAAACTCGGCATCGTGACCAACAAATCCCTGCCGGAACTGCTGGG
CGAGCGTATGAGCGATGCCGGCCGCTTCATGTTCTTCATGCAGGCCGAGGTCATCGCCATCGCCACCGATCTGGCCGAGG
TGATCGGCGGCGCCATCGCCCTGAACCTGCTGTTCGGATTTCCACTGTTCATCGGCGGTTTGGCGATTGGCGTAATCTCC
ACGGTGATGCTGTGGTTCCAAGGCGGCAAGACACAGACCACATTCGAGCGCATCATCATCGTGATGCTGCTGATTATCAC
ATTCGGCTTCATCGCAGGCCTGTTCGTAGCCCCGCCGAACCCCGACGAAGTGGTCAAAGGCATGATTCCACGCTTCCAAG
GCGCCGACTCGGTGTTGATGGCCGCCTCGATTCTGGGCGCCACCGTGATGCCGCACGCCATCTACCTGCACTCCACGCTG
GTGAACGACCATTACGCAGGCGGCGAAAAGCCGTCGATCAAAACGCAGCTGAGAGGCTCGAAAATCGATGTGGCCTGGGC
GCTGTTGCTGGCCGGCACCGTGAATCTGGCGATGCTGGTGCTCGCCGCCAACTCGCTGCATGGCATGTCTGGCACGGACT
CCATCGACGGCGCACAGCGGGCGATCACGCAGGTGCTCGGCCCGGTGATCGGCACGATCTTTTCCATCGGCCTGCTGGCT
TCGTCGCTGAGCTCCACATCGGTCGGCACGTACGCCGGCTCGGAAATCATGCACGGTCTGCTGCACGTTAACGCCCCGAT
GTGGGCCTGCCGCGTGGTCACGCTGGTGCCGGCACTGATTGTGCTGTGGTTCGCCAAGGACCCGACTCAGGCGCTGGTCA
TCGGCCAGGTGGTGCTTTCCATCGGCATCCCGTTCGCCGTGATTCCGCTGATGCGATACACGCATAACAAGGAACTCATG
GGCAAGTGGGCTGATGGAACCGTCAAGCACGTGATCTTTATGATCGTCGTGGCGCTGATTGTGGCGTTGAACGTGCTGCT
GATTGTCCTGACGCTAATGGGCAGGGCGTAA

Upstream 100 bases:

>100_bases
GAAACATGCCTGTGCTATAACTGCGCGCGGTATGAAGGGAACAGGTACAAACAATATGGCAGTAACACACACCGAAGCAG
ATGCCACTGCGGCAACCACT

Downstream 100 bases:

>100_bases
TAGACTCCAGCTGAAATCCTGCGATAGCACAACATAATAAGAAGCCCCGGTGTTGGAAACCGGGGCTTCTTATTATGTTA
AGAATGGTTGAATCTGCCGT

Product: natural resistance-associated macrophage protein

Products: NA

Alternate protein names: BRAMP [H]

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MTNAVADIEQETPEIEKERQLAGAGAGTNNKEKPHDHALASILGPAFVAAVAYVDPGNVAANITSGARYGYLLVWVLVLA
NAMSVLIQYQSAKLGIVTNKSLPELLGERMSDAGRFMFFMQAEVIAIATDLAEVIGGAIALNLLFGFPLFIGGLAIGVIS
TVMLWFQGGKTQTTFERIIIVMLLIITFGFIAGLFVAPPNPDEVVKGMIPRFQGADSVLMAASILGATVMPHAIYLHSTL
VNDHYAGGEKPSIKTQLRGSKIDVAWALLLAGTVNLAMLVLAANSLHGMSGTDSIDGAQRAITQVLGPVIGTIFSIGLLA
SSLSSTSVGTYAGSEIMHGLLHVNAPMWACRVVTLVPALIVLWFAKDPTQALVIGQVVLSIGIPFAVIPLMRYTHNKELM
GKWADGTVKHVIFMIVVALIVALNVLLIVLTLMGRA

Sequences:

>Translated_436_residues
MTNAVADIEQETPEIEKERQLAGAGAGTNNKEKPHDHALASILGPAFVAAVAYVDPGNVAANITSGARYGYLLVWVLVLA
NAMSVLIQYQSAKLGIVTNKSLPELLGERMSDAGRFMFFMQAEVIAIATDLAEVIGGAIALNLLFGFPLFIGGLAIGVIS
TVMLWFQGGKTQTTFERIIIVMLLIITFGFIAGLFVAPPNPDEVVKGMIPRFQGADSVLMAASILGATVMPHAIYLHSTL
VNDHYAGGEKPSIKTQLRGSKIDVAWALLLAGTVNLAMLVLAANSLHGMSGTDSIDGAQRAITQVLGPVIGTIFSIGLLA
SSLSSTSVGTYAGSEIMHGLLHVNAPMWACRVVTLVPALIVLWFAKDPTQALVIGQVVLSIGIPFAVIPLMRYTHNKELM
GKWADGTVKHVIFMIVVALIVALNVLLIVLTLMGRA
>Mature_435_residues
TNAVADIEQETPEIEKERQLAGAGAGTNNKEKPHDHALASILGPAFVAAVAYVDPGNVAANITSGARYGYLLVWVLVLAN
AMSVLIQYQSAKLGIVTNKSLPELLGERMSDAGRFMFFMQAEVIAIATDLAEVIGGAIALNLLFGFPLFIGGLAIGVIST
VMLWFQGGKTQTTFERIIIVMLLIITFGFIAGLFVAPPNPDEVVKGMIPRFQGADSVLMAASILGATVMPHAIYLHSTLV
NDHYAGGEKPSIKTQLRGSKIDVAWALLLAGTVNLAMLVLAANSLHGMSGTDSIDGAQRAITQVLGPVIGTIFSIGLLAS
SLSSTSVGTYAGSEIMHGLLHVNAPMWACRVVTLVPALIVLWFAKDPTQALVIGQVVLSIGIPFAVIPLMRYTHNKELMG
KWADGTVKHVIFMIVVALIVALNVLLIVLTLMGRA

Specific function: H(+)-stimulated, highly selective, manganese uptake system [H]

COG id: COG1914

COG function: function code P; Mn2+ and Fe2+ transporters of the NRAMP family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the NRAMP family [H]

Homologues:

Organism=Homo sapiens, GI109255241, Length=435, Percent_Identity=30.1149425287356, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI295293175, Length=435, Percent_Identity=28.735632183908, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI295293173, Length=435, Percent_Identity=28.735632183908, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI10835169, Length=435, Percent_Identity=28.735632183908, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI295293167, Length=435, Percent_Identity=28.735632183908, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI295293178, Length=435, Percent_Identity=28.735632183908, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI295293171, Length=435, Percent_Identity=28.735632183908, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI295293169, Length=435, Percent_Identity=28.735632183908, Blast_Score=134, Evalue=2e-31,
Organism=Escherichia coli, GI1788736, Length=397, Percent_Identity=41.3098236775819, Blast_Score=278, Evalue=6e-76,
Organism=Caenorhabditis elegans, GI193210616, Length=469, Percent_Identity=28.1449893390192, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71999499, Length=468, Percent_Identity=27.1367521367521, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17569473, Length=366, Percent_Identity=30.8743169398907, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI71993856, Length=442, Percent_Identity=26.2443438914027, Blast_Score=137, Evalue=1e-32,
Organism=Saccharomyces cerevisiae, GI6323062, Length=394, Percent_Identity=32.741116751269, Blast_Score=173, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6324450, Length=470, Percent_Identity=28.936170212766, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321841, Length=407, Percent_Identity=29.97542997543, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24648607, Length=439, Percent_Identity=28.246013667426, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI281362176, Length=439, Percent_Identity=28.246013667426, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24648609, Length=439, Percent_Identity=28.246013667426, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI45553443, Length=415, Percent_Identity=29.3975903614458, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005025
- InterPro:   IPR023056
- InterPro:   IPR001046 [H]

Pfam domain/function: PF03358 FMN_red; PF01566 Nramp [H]

EC number: NA

Molecular weight: Translated: 46160; Mature: 46029

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNAVADIEQETPEIEKERQLAGAGAGTNNKEKPHDHALASILGPAFVAAVAYVDPGNVA
CCCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCE
ANITSGARYGYLLVWVLVLANAMSVLIQYQSAKLGIVTNKSLPELLGERMSDAGRFMFFM
EECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCHHEHHHH
QAEVIAIATDLAEVIGGAIALNLLFGFPLFIGGLAIGVISTVMLWFQGGKTQTTFERIII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VMLLIITFGFIAGLFVAPPNPDEVVKGMIPRFQGADSVLMAASILGATVMPHAIYLHSTL
HHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNDHYAGGEKPSIKTQLRGSKIDVAWALLLAGTVNLAMLVLAANSLHGMSGTDSIDGAQR
HCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
AITQVLGPVIGTIFSIGLLASSLSSTSVGTYAGSEIMHGLLHVNAPMWACRVVTLVPALI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
VLWFAKDPTQALVIGQVVLSIGIPFAVIPLMRYTHNKELMGKWADGTVKHVIFMIVVALI
HHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHH
VALNVLLIVLTLMGRA
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TNAVADIEQETPEIEKERQLAGAGAGTNNKEKPHDHALASILGPAFVAAVAYVDPGNVA
CCCHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEECCCCCE
ANITSGARYGYLLVWVLVLANAMSVLIQYQSAKLGIVTNKSLPELLGERMSDAGRFMFFM
EECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHCCHHEHHHH
QAEVIAIATDLAEVIGGAIALNLLFGFPLFIGGLAIGVISTVMLWFQGGKTQTTFERIII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
VMLLIITFGFIAGLFVAPPNPDEVVKGMIPRFQGADSVLMAASILGATVMPHAIYLHSTL
HHHHHHHHHHHHHEECCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VNDHYAGGEKPSIKTQLRGSKIDVAWALLLAGTVNLAMLVLAANSLHGMSGTDSIDGAQR
HCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
AITQVLGPVIGTIFSIGLLASSLSSTSVGTYAGSEIMHGLLHVNAPMWACRVVTLVPALI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHH
VLWFAKDPTQALVIGQVVLSIGIPFAVIPLMRYTHNKELMGKWADGTVKHVIFMIVVALI
HHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHH
VALNVLLIVLTLMGRA
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972; 9632246 [H]